Abstract: The present invention discloses a grain germinating system comprising a temperature controlling device, an incubation device, a drying device and a monitoring device. The temperature controlling device comprises a heat pump module, an air conditioning module and a piping module. The heat pump module can output a high or low temperature heat exchanging liquid. The temperature of a culture medium of a grain is adjusted by the incubation device. The incubated grain is dried by the drying device. The air conditioning module is for a plant building. The piping module is connected with the heat pump module, and is provided for the high or low temperature heat exchanging liquid to flow. The incubation device and the drying device are heated by the high temperature heat exchanging liquid. The drying device is cooled by the low temperature heat exchanging liquid provided for the air condition of the plant building to use.
Abstract: The present invention provides a composition for treating an articular cartilage defect and a manufacturing method thereof. The composition comprises a cartilage fragment and platelet-rich fibrin (PRF), and is transplanted to a surface of the defective cartilage of a mammal in order to treat the articular cartilage defect. Wherein the cartilage fragment is acquired from the cartilage of the same mammal, and the PRF is acquired from the blood of the same mammal.
Abstract: The invention provides an isolated antigen polypeptide that can be expressed in a subject with ovarian cancer. Also provided is the diagnosis of ovarian cancer by using the antigen polypeptide of the invention and the prevention and/or treatment of ovarian cancer by suppressing the gene of the antigen polypeptide of the invention.
Abstract: A method is provided for generating real-time haptic response information for a haptic simulating device during a surgery simulation performed by a virtual tool on an object volume that includes tissue voxels, null voxels, and object boundary points. The method includes: (a) receiving a select input of a selected virtual tool type; (b) obtaining tool boundary points of the virtual tool; (c) obtaining a current reference position of the virtual tool; (d) determining a current tool subvolume; and (e) when the current tool subvolume has at least one tissue voxel, (e-1) determining positions of the tool boundary points within the subvolume, (e-2) updating labels of the voxels within the subvolume and replacing an original set of the object boundary points within the subvolume with a new set of the object boundary points, (e-3) determining force-contributing ones of the tool boundary points, and (e-4) providing force information of a force to be generated by the haptic simulating device.
Type:
Application
Filed:
August 2, 2010
Publication date:
March 17, 2011
Applicants:
CHUNG YUAN CHRISTIAN UNIVERSITY, TAIPEI MEDICAL UNIVERSITY
Abstract: A method for increasing an amount of effective constituents from a plant in a solvent is provided. The method comprises steps of treating the solvent with a far-infrared radiating (FIR) material and extracting the effective constituents from the plant by the treated solvent for increasing the amount of the effective constituents dissolved in the solvent.
Type:
Grant
Filed:
September 18, 2007
Date of Patent:
March 15, 2011
Assignees:
National Applied Research Laboratories, Taipei Medical University
Abstract: Aryl substituted sulfonamide compounds of formula (I): wherein bond, X, Y, R1, R2, R3, m, and n are defined herein. Also disclosed is a method for treating cancer with these compounds.
Type:
Application
Filed:
August 9, 2010
Publication date:
February 17, 2011
Applicants:
Taipei Medical University, DCB-USA LLC
Abstract: This invention discloses a method for making rice bran flour by treating rice bran under high pressure and high temperature for a long period of time in two separate steps, the method comprising: husking and grinding the rice, then collecting the rice bran; inactivating the lipase of the rice bran; treating the rice bran under high pressure and high temperature; drying and screening the rice bran; treating the rice bran flour so obtained under high pressure and high temperature again; and cooling the rice bran. Said rice bran flour made from said method is effective in lowering glycosylated hemoglobin and increasing insulin of diabetes mellitus patients.
Abstract: The invention provides a dry powder microparticle for pulmonary delivery, which comprises at least one nanoparticle in the form of liposome or micelle wherein the nanopaparticle encapsulates one or more therapeutic agent therein, and a diluent layer surrounding the nanaparticles.
Type:
Application
Filed:
June 8, 2009
Publication date:
December 9, 2010
Applicant:
TAIPEI MEDICAL UNIVERSITY
Inventors:
Tsuimin Tsai, Chin-Tin Chen, Jen-Chang Yang, Yu-Tsai Yang
Abstract: The invention provides a Pyracantha koidzumii extract and new compounds isolated from the extract and their derivatives. This extract and these compounds have activity in inhibiting tyrosinase.
Type:
Grant
Filed:
January 23, 2009
Date of Patent:
November 23, 2010
Assignee:
Taipei Medical University
Inventors:
Mei-Hsien Lee, Feng-Lin Hsu, Yan-Ling Liu
Abstract: The present invention provides a method for the treatment and/or prevention of bacterial infection caused by Klebsiella pneumoniae and other gram-negative bacteria in central nervous system and/or peripheral blood circulation in a mammal by administering effective amount of outer membrane protein A (OmpA) or its derivatives to a mammal. Also provided are a method for vaccinating a mammal to produce an antibody against bacterial infection caused by Enterobacteriaceae family in central nervous system and/or peripheral blood circulation and a method of detecting or diagnosing bacterial infections caused by Enterobacteriaceae family in central nervous system and/or peripheral blood circulation in a mammal.
Abstract: The invention develops a high-throughput screening method based on charcoal-sorbent peptide binding assay (CPBA) which does not need a solid phase and can simultaneously detect plural target biomolecules in a sample. The method of the invention can achieve high-throughput screening of biomolecules (such as antibodies and antigens) with a molecular weight of more than 10 KD.
Abstract: This invention relates to the use of pterosin compounds of formula I for treating diabetes including type I and type II. Also disclosed is the use of the pterosin compounds for treating obesity.
Type:
Application
Filed:
January 26, 2010
Publication date:
July 29, 2010
Applicants:
Taipei Medical University, National Taiwan University, National Tsing Hua University, DCB-USA, LLC
Inventors:
Feng-Lin Hsu, Shing-Hwa Liu, Biing-Jiun Uang
Abstract: The invention provides a Pyracantha koidzumii extract and new compounds isolated from the extract and their derivatives. This extract and these compounds have activity in inhibiting tyrosinase.
Type:
Application
Filed:
January 23, 2009
Publication date:
July 29, 2010
Applicant:
TAIPEI MEDICAL UNIVERSITY
Inventors:
Mei-Hsien Lee, Feng-Lin Hsu, Yan-Ling Liu
Abstract: The present invention provides an extract of Taiwanese wild grape (Vitis thunbergii var. taiwaniana), which is prepared by extracting one or more tissues of Vitis thunbergii var. taiwaniana with 10 wt % to 100 wt % alcohol solution or water to obtain an extract solution, and then drying said extract solution. The extract of Vitis thunbergii var. taiwaniana of the present invention has the function of regulating blood pressure, and therefore can be used to prevent and treat hypertension. The present invention also provides a method for purifying (+)-vitisin A and ampelopsin C from Vitis thunbergii var. taiwaniana and a use of these two compounds for hypertension prevention and treatment.
Abstract: An electrospinning equipment is provided. The electrospinning equipment includes a power supply, a collector and a material supply electrically connected to the power supply facing the collector and having a spinneret and a guide unit coupled to the spinneret and bent toward the collector, and the spinneret is configured at a central portion of the guide unit.
Type:
Application
Filed:
March 15, 2010
Publication date:
July 8, 2010
Applicants:
NATIONAL APPLIED RESEARCH LABORATORIES, TAIPEI MEDICAL UNIVERSITY
Inventors:
Kuen-Wey Shieh, Chien-Chung Chen, Yung-Sheng Lin
Abstract: The present invention relates to a method for controlling blood glucose level and a method for the prophylaxis or treatment of diabetes mellitus and/or its complications. The present invention further relates to an anti-diabetic formulation for controlling blood glucose level and/or for the prophylaxis or treatment of diabetes mellitus and/or its complications.
Abstract: A series of indoline-sulfonamide compounds is disclosed. The formula of indoline-sulfonamide compounds is shown as formula (I). In formula (I), R1 is H or halogen; R2 is Ar, Ar—C(O)—, Ar—CH2—, Ar—SO2—, Ar—O—C(O), or R?—C(O)—, and Ar is a substituted or unsubstituted C5-C20 aryl, cyclyl, heterocyclyl, or heteroaryl, R? and R? independently is C1-C10 alkyl, or C1-C10 alkoxyl; and R3 is C5-C15 aryl or C1-C10 alkyl. The indoline-sulfonamide compounds disclosed in the present invention are characterized in inhibiting tubulin polymerization, and treating cancers and other tubulin polymerization-related disorders with a suitable pharmaceutical acceptable carrier.
Type:
Grant
Filed:
May 10, 2007
Date of Patent:
June 22, 2010
Assignees:
Taipei Medical University, National Health Research Institutes
Abstract: A novel amorphous divalent metal ion salt for enhancing the manageability of a Portland cement and its application in dental field are disclosed. Typical formula (I), (II), or (III) of this amorphous metal ion salt are shown as following: M 2 + ? A x - ? B 2 - x - ( I ) M 2 + ? A y 2 - ? C ( 4 - y ) 4 2 - ( II ) M 2 + ? A z 3 - ? D ( 6 - z ) 9 3 - ( III ) wherein, M2+, A?, B?, C?2, D?3, x, y, and z are defined the same as the specification. A novel tooth filling material comprises: a Portland cement, a bone substitute substance, and an amorphous divalent metal ion salt with formula of (I), (II), or (III). In addition, a novel root canal filling material comprises: a Portland cement, a radiopaque substance, and an amorphous divalent metal ion salt with formula of (I), (II), or (III).
Type:
Application
Filed:
December 1, 2009
Publication date:
June 10, 2010
Applicant:
Taipei Medical University
Inventors:
Jeng-Chang Yang, Pei-Ying Lee, Dain-Yu Ji, Nain-Chia Teng, Sung-Chih Hsieh, Sheng-Yang Lee
Abstract: The invention relates to the compounds isolated from Evodia rutaecarpa (Juss.), in that has been demonstrated to inhibit topoisomerase I. Evodiamine, an alkaloidal compound is reported the topoisomerase I inhibitory activity. The effect of evodiamine acts by stabilizing the covalent complex between topoisomerase I and DNA, which results in a blockade of DNA replication and transcription.
Abstract: A method for preparing amorphous calcium phosphate (ACP) and oral care composition containing ACP prepared by the same are disclosed, wherein the method comprises the following steps: (a) cleaning and pulverizing the oyster shells; (b) sintering the oyster shells to obtain a calcium-containing powder; (c) dissolving the calcium-containing powder in water to obtain a calcium-containing solution; and (d) mixing the calcium-containing solution with a other phosphate-containing solution, to produce amorphous calcium phosphate. The method of the present invention not only can simplify the process and reduce the cost, but also can solve the problem of environment pollution resulting from wasted oyster shells. In addition, the ACP prepared in accordance with the method of the present invention further comprises some trace elements, such as strontium (Sr) and fluoride (F), which can improve dental health.
Type:
Application
Filed:
August 28, 2009
Publication date:
June 10, 2010
Applicant:
Taipei Medical University
Inventors:
Jen-Chang Yang, Dian-Yu Ji, Chien-Chung Chen, Haw-Ming Huang, Sheng-Yang Lee