Abstract: Anti CMV antibodies are provided. Thus an antibody of the present invention comprises an antigen recognition domain capable of binding an MHC molecule being complexed with a cytomegalovirus (CMV) pp65 or pp64 peptide, wherein the antibody does not bind said MHC molecule in an absence of said complexed peptide, and wherein the antibody does not bind said peptide in an absence of said MHC molecule. Also provided are methods of using the antibodies.

Abstract: A computerized method of creating a presentation of multidimensional objects in a multidimensional presentation space. The method comprises providing a core element which applies any of functions on a multidimensional object in a multidimensional presentation space, providing a plurality of adaptation components each contains instructions for converting any media object of another of different media types each to a multidimensional object in the multidimensional presentation space, receiving a media object, identifying a matching adaptation component from the adaptation components according to a respective media type of the media object, converting the media objects into a multidimensional object in the multidimensional presentation space using the matching adaptation component, and applying any of the functions on the multidimensional object, using the core element, according to a user selection.

Abstract: A cell culture comprising human foreskin cells, the human foreskin cells being capable of maintaining stem cells in an undifferentiated state when co-cultured therewith.

Abstract: Processes for forming quantum well structures which are characterized by controllable nitride content are provided, as well as superlattice structures, optical devices and optical communication systems based thereon.

Abstract: A method of operating a multi focused acoustic wave source. The method comprises providing the multi focused acoustic wave source, providing a plurality of target acoustic pressures to be applied on a plurality of regions of interest (ROIs) in at least one cellular tissue, computing a transmission pattern of multi-focal acoustic energy according to the plurality of target acoustic pressures, and operating the multi focused acoustic wave source according to the transmission pattern.

Abstract: A device for replenishing ionizable material in a field ionization apparatus is disclosed. The device comprises a heatable reservoir containing the ionizable material, a field ionization electrode structure, and a channel being in fluid communication with said heatable reservoir. The heatable reservoir and the channel are designed and constructed such that when the heatable reservoir is heated to an evaporation temperature of the ionizable material, a flux of vaporized ionizable material is directed along the channel to a tip of the field ionization electrode structure.

Abstract: A method of deforming a geometric object. The method comprises providing a data segment representing a geometric object, defining a contour enclosing the geometric object in the data segment, calculating a plurality of barycentric coordinates having a plurality of complex coefficients according to the enclosing contour, receiving user input to manipulate the enclosing contour to a target contour, and using the plurality of barycentric coordinates according to the target contour for mapping the geometric object to a target geometric object.

Abstract: A disposable endoscope body having an enclosure in its distal end for a non-disposable element, such as a video camera head. Because of its complexity and sensitivity, the camera head is non-disposable and cannot be sterilized. The camera head is sealed in the endoscope body, such that it does not contaminate the patient during the procedure. Sealing is achieved using an end cap. After use, the camera is withdrawn from the proximal end of the endoscope, which, being near to or within the workstation, has not been inserted into the subject and should be free of patient contamination. Passage of the camera out through the proximal end therefore avoids contamination by the patient, such that it can be used again without need for sterilization. A dispensing kit is described, for supplying the sterile endoscope body and for installing and sealing the camera with a minimum of manual intervention.

Abstract: The present disclosure provides pharmaceutical compositions and methods useful for modulating angiogenesis and for inhibiting metastasis, tumors, pulmonary alveolar proteinosis, and fibrosis in a mammalian tissue. Pharmaceutical compositions and methods include inhibitors of LOXL2 expression and activity, such as shRNA targeting LOXL2.

Abstract: Routing method for computing routes over uncertain geo-spatial data whereby only upon visiting the geographic entities it can be determined whether the needed service or product is actually provided and is adequate. When dealing with uncertain data, the returned route may need to go via several entities of the same type. Another routing method consists of finding an efficient and effective route from a starting point to an ending point going trough a predetermined number of objects, wherein each object represents a geographical entity of a unique type, and each object is selected from a distinct set of similar objects.

Abstract: A method of changing the volume of an intra-bilayer membrane space of at least one bilayer membranous structure of a target tissue. The method comprises providing at least one characteristic of a target tissue having at least one bilayer membranous structure, selecting an acoustic energy transmission pattern set to change a volume of an intra-bilayer membrane space of a bilayer membrane of the at least one bilayer membranous structure according to the at least one characteristic, and applying acoustic energy on the target tissue according to the selected acoustic energy transmission pattern.

Abstract: A method of generating pancreatic progenitor cells is disclosed. The method comprises: (a) differentiating stem cells under conditions such that at least a portion of the cells express glucose transporter 2 (GLUT2) so as to generate GLUT2-expressing cells; and (b) enriching for the GLUT2-expressing cells so as to generate a population of GLUT2 enriched cells, wherein at least 80% of the population of GLUT2 enriched cells express GLUT2, thereby generating pancreatic progenitor cells. Isolated populations of cells generated according to the method, pharmaceutical compositions comprising same and uses thereof are also disclosed.

Abstract: A light emitting system is disclosed. The system comprises an active region having a stack of bilayer quantum well structures separated from each other by barrier layers. Each bilayer quantum well structure is formed of a first layer made of a first semiconductor alloy for electron confinement and a second layer made of a second semiconductor alloy for hole confinement, wherein a thickness and composition of each layer is such that a characteristic hole confinement energy of the bilayer quantum well structure is at least 200 meV.

Abstract: Provided is a device comprising at least two layers, said at least two layers being at least partially overlapping (e.g., superposed) and contacting one another, wherein a first layer of said at least two layers comprises a non-biodegradable mesh, and wherein a second layer of the at least two layers comprises an electrospun element, and wherein the device is devoid of an extracellular matrix generated by mesenchymal progenitor cells, which are characterized by a reduced differentiation potential into an adipogenic lineage by at least about 50% as compared to differentiation potential of mesenchymal stem cells from an adult adipose source under identical assay conditions, and by an increased osteogenic differentiation potential by at least about 20% as compared to the osteogenic differentiation potential of adipose-derived MSCs under identical assays conditions.

Abstract: Anti CMV antibodies are provided. Thus an antibody of the present invention comprises an antigen recognition domain capable of binding an MHC molecule being complexed with a cytomegalovirus (CMV) pp65 or pp64 peptide, wherein the antibody does not bind said MHC molecule in an absence of said complexed peptide, and wherein the antibody does not bind said peptide in an absence of said MHC molecule. Also provided are methods of using the antibodies.

Abstract: An isolated primate embryonic cell is provided as well as cell cultures and cell lines derived therefrom. Also provided are methods of generating and using such cells.

Abstract: A method and pharmaceutical compositions useful for inhibiting the growth of solid tumors are provided. Specifically, the method is effected by administering to a subject in need thereof an agent capable of upregulating the expression level and/or activity of at least a functional portion of Sef, wherein the functional portion being capable of inhibiting RTK-mediated cell proliferation. Also provided are methods and kits for diagnosing and staging of cancer by detecting the expression level of hSef in a tissue sample, wherein a decrease in hSef expression level is indicative of cancer.

Abstract: Antibodies are provided. For as example, an antibody capable of binding an artificial receptor which comprises a hydroquinone monolayer and is incapable of binding the artificial receptor when comprising a benzoquinone monolayer. Also provided are methods and systems using same for control delivery of a molecule-of-interest into a tissue.

Abstract: A robotic system for steering a flexible needle during insertion into soft-tissue using imaging to determine the needle position. The control system calculates a needle tip trajectory that hits the desired target while avoiding potentially dangerous obstacles en route. Using an inverse kinematics algorithm, the maneuvers required of the needle base to cause the tip to follow this trajectory are calculated, such that the robot can perform controlled needle insertion. The insertion of a flexible needle into a deformable tissue is modeled as a linear beam supported by virtual springs, where the stiffness coefficients of the springs varies along the needle. The forward and inverse kinematics of the needle are solved analytically, enabling both path planning and correction in real-time. The needle shape is detected by image processing performed on fluoroscopic images. The stiffness properties of the tissue are calculated from the measured shape of the needle.

Abstract: Methods of generating and expanding proliferative, multipotent connective tissue progenitor cells from embryonic stem cells and embryoid bodies are provided. Also provided are methods of generating functional tendon grafts in vitro and bone, cartilage and connective tissues in vivo using the isolated cell preparation of connective tissue progenitor cells.