Abstract: A three-dimensional fibrin engineered tissue construct is provided selected from: (i) a fibrin gel matrix comprising a combination of tissue-specific cells and at least one type of vascular cells; and (ii) a hybrid scaffold of fibrin gel and a polymeric synthetic scaffold comprising at least one type of vascular cells or a combination of tissue-specific cells and at least one type of vascular cells.

Abstract: A method of expanding and maintaining human embryonic stem cells (ESCs) in an undifferentiated state by culturing the ESCs in a suspension culture under culturing conditions devoid of substrate adherence is provided. Also provided are a method of deriving ESC lines in the suspension culture and methods of generating lineage-specific cells from ESCs which were expanded in the suspension culture of the present invention.

Abstract: Provided is a superabsorbent structure based on a covalently crosslinked copolymer having a microstructure of a HIPE, and characterized by hydrophobic and hydrophilic segments of at least five residues; the unique chemical and structural properties of the copolymer afford a polymeric superabsorbent structure that is capable of swelling in polar as well as apolar media. Also provided are processes of manufacturing the superabsorbent structure, and uses thereof.

Abstract: A method tor the preparation of a highly polarized nuclear spins containing sample of an organic or inorganic material, containing H or OH groups or adsorbed water molecules. Such highly polarized nuclear spins containing samples can be subjected to nuclear magnetic resonance (NMR) measurement and/or can be thawed and immediately administered to an individual undergoing a magnetic resonance imaging (MRI) scan. The method is based on generating unstable radicals on the surface of the sample in the presence of ionized environment followed by cooling the sample to cryogenic temperatures. A device for carrying out a particular step of said method is also discloses.

Abstract: A system and method to measure blood oxygenation levels and total hemoglobin on individually selected blood vessels, to provide a representation of the subject condition and of tissue perfusion that may be used for diagnosing specific tissue conditions. Reflection spectra from individual blood vessels or a collection of vessels are measured by using wide-field imaging for selecting target vessels and a narrow-field confocal detection system to enable measuring local blood oxygenation and hemoglobin. Optical fibers may be used to illuminate the target vessel and to detect light diffusively reflected therefrom. The reflection spectra may be analyzed in a spectrometer to extract the ratio of the deoxy- to oxyhemoglobin and to determine their absolute concentration for computing total hemoglobin levels. An alternative implementation uses image processing on camera images of a blood vessel, generated at an isosbestic wavelength of the deoxy- and oxyhemoglobin, and optionally also at neighboring wavelengths.

Abstract: A sensing device that may include a substrate; a single-ended SPAD; first electrical components; second electrical components; and capacitors. The SPAD, the first electrical components and the second electrical components are formed on the substrate. The SPAD and the first electrical components belong to a high voltage domain of the sensing device. The high voltage domain is configured to receive a high supply voltage that exceeds a breakdown voltage of the SPAD. The second electrical components belong to a low voltage domain of the sensing device. The capacitors are coupled between the low voltage domain and the high voltage domain. The first electrical components and the second electrical components belong to an electrical circuit that is configured to perform quenching of the SPAD.

Abstract: An atmospheric moisture harvesting system, in which water vapor is separated from the air using a liquid desiccant subsystem. The moisture charged liquid desiccant enters a desorber and condensation system, where the moisture is extracted. Cooling and condensation are performed on the extracted water vapor only, thereby saving the energy for cooling air containing the water vapor, as is done in direct cooling systems. The system thus operates as a single stage vapor separation system since the vapor concentration remains in the liquid desiccant which is circulated to the separation and condensation subsystems without air laden with the moisture. Low grade or solar heat can be used as the energy source for the vapor desorption. A heat exchanger utilizes unwanted heat from regenerated desiccant to heat up charged desiccant entering the regenerating stage. The system has substantial energy savings over prior art systems using direct cooling of air.

Abstract: A composite comprised of: (i) at least one inverse freezing material, and (ii) an additive in the form of at least one solid particle. Articles made of the composites, and uses of the composites or the articles incorporating same, particularly for reducing incoming shockwaves, are also disclosed.

Abstract: The invention provides compositions, kits and methods for depositing a composition comprising a plurality of magnetic particles, to a target site of a subject by delivering the composition via controlled inhalation to a region of the subject's respiratory tract and applying a magnetic field to a target site within the region of the subject's respiratory tract to capture the particles in said target site.

Abstract: A method for detecting a pattern of events, comprising: receiving a template defining the pattern of events to detect; producing a join query for a relational database from the template; selecting a cost function for the join query, wherein a computation cost of the join query is equivalent to a computation cost of matching between a plurality of events from a plurality of streams of events and the template; identifying a preferred plan for executing the join query according to a minimal value of the cost function; producing an ordered set of a plurality of patterns, according to the preferred plan, by converting a plurality of database operations of the preferred plan into the ordered set of the plurality of patterns; and using the ordered set as an input for detecting a plurality of matches between the plurality of patterns and the plurality of events.

Abstract: A system for generating cold plasma is presented, suitable for use in in-vivo treatment of biological tissue. The system comprising: a control unit connectable to an elongated member at a first proximal end of the elongated member. The elongated member comprises a plasma generating unit at a second distal end thereof and gas and electricity transmission channels extending from said first proximal end towards said plasma generating unit. The control unit comprises a gas supply unit configured to provide predetermined flow rate of selected gas composition through said gas transmission channel and a power supply unit configured to generate selected sequence of high-frequency electrical pulses, typically in mega Hertz range, directed through said electricity transmission channel, thereby providing power and gas of said selected composition to the plasma generating unit for generating cold plasma.

Abstract: A digital to analog converter is constructed using a neural network layer. The converter has inputs for receiving parallel bits of a digital input signal and an output for outputting an analog signal which is based on the digital input. Connecting the input and the output is a neural network layer which is configured to convert the parallel bits into an output analog signal that is representative of the digital input signal. The neural network may be hardwired and the synapses may rely on memristors as programmable elements.

Abstract: A method of applying proof of lottery to select block forgers in a blockchain, comprising performing the following at a certain one of a plurality of computing nodes connected to a blockchain network: (1) transmitting one or more of a plurality of participation transactions submitted by at least some of the plurality of computing nodes for participating in selection process conducted to select forgers from the plurality of computing nodes to forge blocks to be added to the blockchain; (2) determining a respective forger, during each selection process, by applying a selection function to an outcome of a hash function and a plurality of participation transactions extracted from a first subset of blocks preceding the respective block, the hash function is applied to a second subset of blocks preceding the respective block; and (3) forging the respective block in case the certain computing node is selected as the respective forger.

Abstract: A method of manipulating a living cell is disclosed. The method comprises, directing a pulsed optical field to at least one conductive nanoparticle present in the vicinity of the cell, so as to generate cavitations at or near the conductive nanoparticle at sufficient amount to effect at least one cell modification selected from the group consisting of cell-damage and cell-fusion.

Abstract: Provided herein is a superabsorbent polyHIPE composition-of-matter comprising a majority of ionizable pendant groups, capable of absorbing up to 300-fold by mass water while exhibiting a notable mechanical strength in both the dry and wet form, as well as various uses thereof.

Abstract: A hybrid computer that comprises a sequential processor, a single instruction massively parallel (SIMD) processor, and shared memory module that is shared between the sequential processor and the SIMD processor.

Abstract: A tracking system, comprising: multiple beacons, each associated with a different cyclic equivalence class of code-word length n, and each configured to broadcast a bit-stream comprising a repeating code-word, where the code-word belongs to the associated cyclic equivalence class; and a mobile tracking unit, comprising: a sensor, and a processor, wherein the sensor is configured to simultaneously detects at least some of the bit streams, and provide each sensed bit stream in real-time to the processor, wherein for each bit-stream received by the processor from the sensor, the processor is configured to identify the beacon that broadcasted the bit-stream using the first n received bits.

Abstract: Provided are physico-chemical processes for continuous and simultaneous water disinfection, oxidation of off flavor agents, minimization of trihalomethane (THM) production, reduction of nitrate and nitrite production and oxidation of ammonia so as to remove nitrogen species, in saline (for example, seawater) based aquaculture systems. The aquaculture system may be any handling/storage/transport system, for example, recirculated aquaculture systems (RAS), for fish or other aquaculture species.

Abstract: An imaging apparatus (20) includes an interface (50) and a processor (30). The interface is configured to receive a sequence of images of an object (38) acquired at respective acquisition times, the object is labeled with fluorescent emitters. The images depict intensity fluctuations of emitters on an acquisition grid, and the intensity fluctuations being uncorrelated among the emitters and during an overall time over which the images in the sequence are acquired. The a processor is configured to calculate a temporal correlation function of the intensity fluctuations over the sequence of images, and to estimate locations of the emitters on a super-resolution grid having a higher resolution than the acquisition grid, by applying to the temporal correlation function a recovery process in which the locations on the super-resolution grid are assumed to be sparse or compressible in a predefined domain. The recovery process includes a sparse-recovery process or a regularized process.

Abstract: A new class of pseudo-trisaccharide aminoglycosides having an alkyl group at the 5? position, exhibiting efficient stop codon mutation readthrough activity, low cytotoxicity and high selectivity towards eukaryotic translation systems are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders, as well as processes of preparing these aminoglycosides. The disclosed aminoglycosides can be represented by the general formula I: or a pharmaceutically acceptable salt thereof, wherein R1 is selected from the group consisting of alkyl, cycloalkyl and aryl; and all other variables and features are as described in the specification.