Patents Assigned to Technion Research & Development
  • Vessel imaging system and method
    Patent number: 10646160
    Abstract: A method for locating a vessel, the method comprising illuminating at least a portion of the vessel with a background light having a substantially high susceptibility to absorption by particles in said portion of the vessel; detecting backscattered light from said illuminated portion of the vessel; reproducing an image from said backscattered light; and identifying dark regions within said reproduced image.
    Type: Grant
    Filed: January 17, 2013
    Date of Patent: May 12, 2020
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Dvir Yelin, Lior Golan
  • Method for passive metal activation and uses thereof
    Patent number: 10644304
    Abstract: Disclosed is a method for activating a surface of metals, such as self-passivated metals, and of metal-oxide dissolution, effected using a fluoroanion-containing composition. Also disclosed is an electrochemical cell utilizing an aluminum-containing anode material and a fluoroanion-containing electrolyte, characterized by high efficiency, low corrosion, and optionally mechanical or electrochemical rechargeability. Also disclosed is a process for fusing (welding, soldering etc.) a self-passivated metal at relatively low temperature and ambient atmosphere, and a method for electrodepositing a metal on a self-passivated metal using metal-oxide source.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: May 5, 2020
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Yair Ein-Eli, Danny Gelman, Boris Shvartsev, Alexander Kraytsberg
  • LIQUID-RETAINING ELASTOMERIC COMPOSITIONS, PROCESS OF PREPARATION AND USES THEREOF
    Publication number: 20200123338
    Abstract: Provided are compositions-of-matter comprising a continuous elastomeric matrix that is structurally-templated by an external phase of a high internal phase emulsion (HIPE), and a liquid dispersed and entrapped in the elastomeric matrix in a form of a plurality of discrete liquid-filled voids. Also provided are processes for obtaining said compositions-of-matter and uses thereof.
    Type: Application
    Filed: July 10, 2018
    Publication date: April 23, 2020
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Michael S. SILVERSTEIN, Sharon NIV
  • Methods of generating lineage-specific cells from undifferentiated human pluripotent stem cells cultured in a single cell suspension culture
    Patent number: 10597635
    Abstract: Provided is an isolated population of human pluripotent stem cells comprising at least 50% human pluripotent stem cells characterized by an OCT4+/TRA1-60?/TRA1-81?/SSEA1+/SSEA4? expression signature, and novel methods of generating and maintaining same in a pluripotent, undifferentiated state a suspension culture devoid of cell clumps. Also provided are novel culture media, cell cultures and methods for culturing pluripotent stem cells in a suspension culture or a two-dimensional culture system while maintaining the cells in a proliferative, pluripotent and undifferentiated state. The novel culture media comprise interleukin 11 (IL11) and Ciliay Neurotrophic Factor (CNTF); bFGF at a concentration of at least 50 ng/ml and an IL6RIL6 chimera; or an animal contaminant-free serum replacement and an IL6RIL6 chimera. Also provided are methods for generating lineage-specific cells from the pluripotent stem cells.
    Type: Grant
    Filed: January 11, 2017
    Date of Patent: March 24, 2020
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Michal Amit, Joseph Itskovitz-Eldor
  • Medium comprising transforming growth factor beta 1 and basic fibroblast growth factor
    Patent number: 10590382
    Abstract: The present invention is of methods of establishing and propagating human embryonic stem cell lines using feeder cells-free, xeno-free culture systems and stem cells which are capable of being maintained in an undifferentiated, pluripotent and proliferative state in culture which is free of xeno contaminants and feeder cells.
    Type: Grant
    Filed: September 3, 2018
    Date of Patent: March 17, 2020
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Michal Amit, Joseph Itskovitz-Eldor
  • AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS
    Publication number: 20200078386
    Abstract: A new class of pseudo-trisaccharide aminoglycosides having an alkyl group at the 5? position, exhibiting efficient stop codon mutation readthrough activity, low cytotoxicity and high selectivity towards eukaryotic translation systems are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders, as well as processes of preparing these aminoglycosides. The disclosed aminoglycosides can be represented by the general formula I: or a pharmaceutically acceptable salt thereof, wherein R1 is selected from the group consisting of alkyl, cycloalkyl and aryl; and all other variables and features are as described in the specification.
    Type: Application
    Filed: August 23, 2019
    Publication date: March 12, 2020
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Timor BAASOV, Dana ATIA-GLIKIN, Jeyakumar KANDASAMY, Valery BELAKHOV
  • Tip propelled device for motion through a passage
    Patent number: 10583273
    Abstract: A self-propelled device for locomotion through a lumen, comprising a set of serially arranged inflatable chambers, the end ones of which expand at least radially when inflated. Connecting passages provide fluid communication between each pair of adjacent chambers. A fluid source is attached to one of the end chambers. The connecting passages are such that the fluid inflates the chambers in a sequence, beginning with the chamber closest to the source, and ending with the chamber furthest from the source. The same sequence occurs when the chambers deflate, beginning with the chamber closest to the source, and ending with the chamber furthest from the source. The fluid source can either be a fluid supply tube, extending to a supply outside the lumen, or it can be built-in and carried by the device. The device can crawl either along the lumen wall or on an inserted guide wire.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: March 10, 2020
    Assignee: Technion Research & Development Foundation Ltd.
    Inventors: Moshe Shoham, Noam Hassidov, Daniel Glozman
  • MODIFIED PEPTOIDS
    Publication number: 20200055897
    Abstract: Peptoids are described herein, as well as compositions comprising an aqueous liquid and a peptoid soluble in the aqueous liquid. The peptoids comprise a plurality of N-substituted glycine residues and/or N-substituted ?-alanine residues, and at least one heteroalicyclic residue having a general formula: wherein W, X, Y1, Y2, Z1 and Z2 are as defined herein.
    Type: Application
    Filed: April 26, 2018
    Publication date: February 20, 2020
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Galia MAAYAN, Kaniraj Jeya PRATHAP
  • USE OF CASPASE-3 INHIBITORS AND CASPASE-3 ACTIVATORS IN THE MANUFACTURE OF MEDICAMENT FOR TREATING CANCER AND WOUND HEALING
    Publication number: 20200046796
    Abstract: Provided are methods of selecting a treatment for a cancer in a subject in need thereof, by analyzing activity of Yes associated protein 1 (YAP) in cancer cells of the subject, and methods of treating cancer using a therapeutically effective amount of an caspase-3 inhibitor. Also provided are methods of improving wound healing by administering a wound healing effective amount of a caspase-3 activator.
    Type: Application
    Filed: October 13, 2017
    Publication date: February 13, 2020
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Yaron FUCHS, Yahav YOSEFZON, Despina SOTERIOU
  • INTERACTIVE CHANNEL
    Publication number: 20200045509
    Abstract: A channel distribution system has a channel carrying content, and an interactive receiver which receives content and provides to a user. The interactive receiver has an interface to allow the user to interact with the content. The channel also includes a broadcast label superimposed on the content which invites the user to interact with the content. The label includes an interactive link with a digital instruction containing handling information for the interactive receiver device. The handling information tells the interactive receiver how to handle a user interaction coinciding with the label.
    Type: Application
    Filed: October 14, 2019
    Publication date: February 6, 2020
    Applicant: Technion Research & Development Foundation Limited
    Inventor: Oded SHMUELI
  • METHODS AND SYSTEM FOR HYDROGEN PRODUCTION BY WATER ELECTROLYSIS
    Publication number: 20200040467
    Abstract: A system and method for generating hydrogen gas from an aqueous solution are disclosed herein. The system comprises a compartment with a working electrode for reducing water in response to an applied voltage to generate hydrogen and a redox-active electrode capable of reversibly undergoing oxidation and reduction. The system may further comprise a second compartment with a working electrode for generating oxygen and redox-active electrode electrically connectable to the redox-active electrode in the first compartment. The method comprises applying a voltage between a working electrode and a redox-active electrode of a system described herein and/or between comprising a working electrode of one compartment and a working electrode of a second compartment of a system described herein.
    Type: Application
    Filed: October 11, 2019
    Publication date: February 6, 2020
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Avner ROTHSCHILD, Gideon GRADER, Gennady SHTER, Avigail LANDMAN, Hen DOTAN
  • System and method for image capture device pose estimation
    Patent number: 10546385
    Abstract: A method for estimating a plurality of camera, comprising using at least one processor executing a code for: extracting a plurality of image features of a plurality of landmarks from a plurality of images captured by at least one camera from at least one pose, the plurality of landmarks calibrated with respect to a certain coordinate system; identifying among the plurality of image features at least one image feature documented in at least some of the images; producing scale values of at least one common image feature by analyzing the at least some of the images; determining a plurality of estimated poses of the at least one camera with respect to the certain coordinate system by using the scale values in calculating a minimal re-projection error between the plurality of image features and a plurality of predicted image features; and outputting the plurality of estimated poses.
    Type: Grant
    Filed: February 23, 2017
    Date of Patent: January 28, 2020
    Assignee: Technion Research & Development Foundation Limited
    Inventor: Vadim Indelman
  • SUPERABSORBENT POLYMERIC STRUCTURES
    Publication number: 20200016574
    Abstract: Provided herein is a superabsorbent polyHIPE composition-of-matter comprising a majority of ionizable pendant groups, capable of absorbing up to 300-fold by mass water while exhibiting a notable mechanical strength in both the dry and wet form, as well as various uses thereof.
    Type: Application
    Filed: September 24, 2019
    Publication date: January 16, 2020
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Sebastijan KOVACIC, Michael S. SILVERSTEIN
  • Logic design with unipolar memristors
    Patent number: 10516398
    Abstract: Logic gates are made from first and second resistive elements connected together to form a voltage divider. One or both of the resistive elements is a unipolar memristor. OR and NOT gates may be constructed to make a digital logic system.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: December 24, 2019
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Shahar Kvatinsky, Avishay Drori, Elad Amrani
  • Similarity of binaries
    Patent number: 10514909
    Abstract: A computer implemented method of estimating a similarity of binary records comprising executable code, comprising converting a first binary record and a second binary record to a first intermediate representation (IR) and a second IR respectively, decomposing each of the first IR and the second IR to a plurality of strands which are partial dependent chains of program instructions, calculating a probability score for each of the plurality of strands of the first IR to have an equivalent counterpart in the second IR by comparing each strand of the first IR to one or more strands of the second IR, adjusting the probability score for each strand according to a significance value calculated for each strand and calculating a similarity score defining a functional similarity between the first IR and the second IR by aggregating the adjusted probability score of the plurality of strands.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: December 24, 2019
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Eran Yahav, Nimrod Sebban Partush, Moshe Yaniv David
  • ANTIMICROBIAL SUSCEPTIBILITY TEST KITS
    Publication number: 20190374948
    Abstract: A microfluidic device may include a microstructure formed in a substrate, the microstructure including a primary channel with a first end and a second end, and a plurality of chambers that open to the primary channel. At least two openings coupled to the first end of the primary channel may be used to load at least two fluid streams into the device through the first end of the primary channel to flow along the primary channel from the first end to the second end into the plurality of chambers, each chamber of the plurality of chambers having a volume less than 100 nanoliters and connected by a vent to a secondary channel in the micro structure, a width of the vent configured to enable a gas to escape from the chamber to the secondary channel while inhibiting the flow of said at least first and second fluid streams into the secondary channel.
    Type: Application
    Filed: February 23, 2018
    Publication date: December 12, 2019
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Jonathan AVESAR, Shulamit LEVENBERG, Dekel ROSENFELD, Yaron Joseph BLINDER
  • Electronic device
    Patent number: 10497789
    Abstract: A transistor structure is configured as a vertical type transistor. The transistor structure has a patterned electrode located between a gate electrode and a channel region of the transistor structure. The patterned electrode has one or more regions of discontinuity of the electrode. The patterned source electrode has at least two layers having at least a first and second barriers for injection of charge carriers into the channel region. The patterned electrode is configured such that a second layer having a second, higher, barrier for injection of charge carriers is configured to provide a physical barrier for flow of charge carriers from the electrode into the channel region.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: December 3, 2019
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Nir Tessler, Ariel Jacques Ben Sasson, Michael Greenman
  • Methods and system for hydrogen production by water electrolysis
    Patent number: 10487408
    Abstract: A system and method for generating hydrogen gas from an aqueous solution are disclosed herein. The system comprises a compartment with a working electrode for reducing water in response to an applied voltage to generate hydrogen and a redox-active electrode capable of reversibly undergoing oxidation and reduction. The system may further comprise a second compartment with a working electrode for generating oxygen and redox-active electrode electrically connectable to the redox-active electrode in the first compartment. The method comprises applying a voltage between a working electrode and a redox-active electrode of a system described herein and/or between comprising a working electrode of one compartment and a working electrode of a second compartment of a system described herein.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: November 26, 2019
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Avner Rothschild, Gideon Grader, Gennady Shter, Avigail Landman, Hen Dotan
  • LOGIC DESIGN WITH UNIPOLAR MEMRISTORS
    Publication number: 20190326913
    Abstract: Logic gates are made from first and second resistive elements connected together to form a voltage divider. One or both of the resistive elements is a unipolar memristor. OR and NOT gates may be constructed to make a digital logic system.
    Type: Application
    Filed: May 9, 2019
    Publication date: October 24, 2019
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Shahar KVATINSKY, Avishay DRORI, Elad AMRANI
  • Superabsorbent polymeric structures
    Patent number: 10449516
    Abstract: Provided herein is a superabsorbent polyHIPE composition-of-matter comprising a majority of ionizable pendant groups, capable of absorbing up to 300-fold by mass water while exhibiting a notable mechanical strength in both the dry and wet form, as well as various uses thereof.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: October 22, 2019
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Sebastijan Kovacic, Michael S. Silverstein