Abstract: Provided is an isolated population of human pluripotent stem cells comprising at least 50% human pluripotent stem cells characterized by an OCT4+/TRA1-60?/TRA1-81?/SSEA1+/SSEA4? expression signature, and novel methods of generating and maintaining same in a pluripotent, undifferentiated state a suspension culture devoid of cell clumps. Also provided are novel culture media, cell cultures and methods for culturing pluripotent stem cells in a suspension culture or a two-dimensional culture system while maintaining the cells in a proliferative, pluripotent and undifferentiated state. The novel culture media comprise interleukin 11 (IL11) and Ciliary Neurotrophic Factor (CNTF); bFGF at a concentration of at least 50 ng/ml and an IL6RIL6 chimera; or an animal contaminant-free serum replacement and an IL6RIL6 chimera. Also provided are methods for generating lineage-specific cells from the pluripotent stem cells.

Abstract: A specified proton concentration in a volume (80) is produced by passing a controlled electrophoresis current through an adjacent electrophoresis volume (28) between a working electrode (26) and a counter electrode (24). An array of such volumes with specified proton concentration is used to provide the pH gradient for isoelectric focusing.

Abstract: A method of creating a real time synthetic model tracking a dynamic physical entity, comprising: a) Receiving multiple points extracted from a sequence of 3D information depicting a dynamic physical entity, each point is associated with position and photometric information. b) Identifying, within the multiply of points, a cloud point which includes multiple entity representative points which portray a surface of the dynamic physical entity. c) Generating a points-surface for a synthetic model by creating spatial presentation of the entity representative points through calculation of principal curvatures for each entity representative point according to the respective position information. d) Generating a continuous surface for the synthetic model by texturing ellipsoidal shapes created for each entity representative point according to the respective photometric information.

Abstract: Provided are nucleic acid constructs which comprise a polynucleotide encoding adenosine phosphate-isopentenyltransferase (IPT) operably linked to a stress-related promoter. Also provided are host cells transformed with the nucleic acid constructs, transgenic plants expressing the IPT coding sequence under the transcriptional regulation of a stress-related promoter and methods of using same for increasing abiotic stress tolerance of a plant, and biomass of plants under stress or normal conditions.

Abstract: A system for generating a mechanical wave is disclosed. The system comprises a camshaft having plurality of rotatable cams, serially mounted on a shaft along an axis of an elastic tubular shell to form a varying phase angle along the shaft. The system further comprises a plurality of cam followers arranged circumferentially about each cam, such that a rotary motion of the cams generates a linear motion of the cam followers to radially bias in internal wall the shell. The variation of the phase angle is selected to generate a three-dimensional traveling wave along the shell.

Abstract: The present invention provides a halo-de-carboxylation process for the preparation of organic chlorides, organic bromides and mixtures thereof, from their corresponding carboxylic acids, using a chlorinating agent selected from trichloroisocyanuric acid (TCCA), dichloroisocyanuric acid (DCCA), or combination thereof, and a brominating agent.

Abstract: A microparticle for cell encapsulation is provided, having a core which comprises continuous fibers of decellularized extracellular matrix (ECM) and, optionally, an outer layer. Also provided are methods of encapsulating cells in the microparticle, pharmaceutical compositions comprising the microparticle, and methods of treating disease in animals employing the microparticles of the invention, for example, treating Diabetes.

Abstract: The present invention provides a process for the preparation of organic bromides, by a radical bromodecarboxylation of carboxylic acids with a bromoisocyanurate.

Abstract: The present invention is of methods of establishing and propagating human embryonic stem cell lines using feeder cells-free, xeno-free culture systems and stem cells which are capable of being maintained in an undifferentiated, pluripotent and proliferative state in culture which is free of xeno contaminants and feeder cells.

Abstract: A method of processing a set of images of a scene is disclosed. The set is represented by a plurality of picture-elements defining an image plane, and the images are characterized by different light intensity spatial distributions but the same viewpoint relative to the scene. The method comprises: for each of at least some picture-elements, independently selecting a direction parallel to the image plane, constructing a weighted vector field based on the selected direction, and calculating a height of a surface in the scene perpendicular to the image plane based on the constructed weighted vector field. The method further comprises reconstructing a three-dimensional spatial representation of the surface based on the heights; and transmitting the spatial representation to a computer readable medium.

Abstract: A self cleaning inlet head for use on a shunt. The head has a tube with openings disposed in predetermined positions in its wall, and a cleaning element installed inside the tube. The cleaning element may comprise a central shaft with a number of bristles protruding therefrom, preferably in locations substantially identical to the positions of the openings in the wall of the tube. Mutual vibratory motion between the cleaning element and the tube causes at least some of the bristles to enter the openings, thereby keeping them clear, and preventing tissue growth into them. The vibratory motion may be generated by the action of an external field on a responsive part of the cleaning element, such as an external magnetic field operating on a magnetic or magnetized part of the cleaning element or the bristles. Alternatively, the external field may be an ultrasound field operating on the bristles.

Abstract: A system for converting an input oscillation having an input frequency into an output oscillation having an output frequency is disclosed. The system comprises: a controller configured for receiving the input oscillation and responsively generating a multi-component drive signal. A frequency of at least one component of the drive signal is other than two times the input frequency. In some embodiments, a frequency of another component of the drive signal equals about two times the output frequency. The system also comprises an oscillator for generating pump oscillations responsively to the drive signal and applying parametric excitation to the input oscillation at the pump oscillations.

Abstract: Isolated peptides and compositions comprising same are provided. Further, methods for targeting mitochondria in a cell, methods for assessing mitochondrial function in a cell and methods for diagnosing mitochondria associated diseases are provided.

Abstract: A method of processing a query to a graph database using processors. The method comprises providing threads to be executed on processors, each the thread is associated with one of a plurality of unique thread identifiers, providing a graph database having a plurality of graph database nodes and a plurality of graph database edges, each the graph database edge represents a relationship between two of the plurality of graph database nodes, receiving a query tree that defines a tree comprising plurality of query nodes connected by a plurality of query tree edges, and searching at least part of the graph database for a match with the query tree, wherein the searching is executed by the processors, and wherein each processor searches one of a plurality of sub-graphs of the graph database, each the sub-graph is defined by one of the plurality of thread identifiers.

Abstract: A new class of pseudo-trisaccharide aminoglycosides having an alkyl group at the 5? position, exhibiting efficient stop codon mutation readthrough activity, low cytotoxicity and high selectivity towards eukaryotic translation systems are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders, as well as processes of preparing these aminoglycosides. The disclosed aminoglycosides can be represented by the general formula I: or a pharmaceutically acceptable salt thereof, wherein R1 is selected from the group consisting of alkyl, cycloalkyl and aryl; and all other variables and features are as described in the specification.

Abstract: A computerized method of creating a circuit logic model of a VLSI device, comprising mapping a plurality of logic function patterns of one or more circuits of a VLSI device through a plurality of probe iterations and generating a circuit logic model of the circuit(s) by reconstructing a logical function of a combinatorial logic of the circuit(s) based on analysis of the logic function patterns. Each of the probe iteration comprises switching between scan shift mode and functional mode of the VLSI device such that while the VLSI device operates in scan shift mode register(s) associated with the circuit(s) is accessed and while the VLSI device operates in functional mode external pin(s) of the VLSI device associated with the circuit(s) is probed and mapping a respective one of the logic function patterns according to a logic state of one or more bits in the register(s) and/or the external pin(s).

Abstract: A method for managing communication among a plurality of social network members. The method comprises defining a multi participant task, setting at least one forward rule limiting the distribution an invitation message for participating in the multi participant task, forwarding the invitation message to at least one addressee from a plurality of social network members, allowing the at least one addressee to forward the invitation message to at least one additional addressee from the plurality of social network members under the at least one forward rule, monitoring a plurality of feedbacks to the invitation message to determine whether the multi participant task is achieved, and updating a status of the multi participant task according to the determination.

Abstract: An inflatable connector comprising a bladder having at least two pipe securing areas formed as at least two separate cylindrical voids, respectively, in said bladder, wherein said at least two separate cylindrical voids are completely separated by a portion of said bladder and are configured to at least partially encompass at least two pipe portions, respectively, wherein said bladder is configured, when deflated, to enable insertion of said at least two pipe portions into said at least two pipe securing areas, respectively, and wherein said bladder is configured, when inflated, to secure said at least two pipe portions in said at least two pipe securing areas, respectively.

Abstract: Methods and compositions for treating microbial infections associated with an emergence of resistance of a pathogenic microorganism to an antimicrobial agent, following treatment with antimicrobial agent are disclosed. The methods are effected by using a polymer which exhibits antimicrobial re-sensitizing activity, for re-sensitizing the pathogenic microorganisms to the antimicrobial agent, in combination with the antimicrobial agent. Further disclosed are novel polymers having an antimicrobial re-sensitizing activity.

Abstract: A method for making an oil-in-water dispersion or water-in-oil dispersion is disclosed. The method comprises the step of mixing a hydrophilic medium, a hydrophobic composition and non-derivatized cellulose solution in an ionic liquid.