Patents Assigned to Technion Research & Development
  • Publication number: 20200156015
    Abstract: An article comprised of an oxidized carbon nanotube (CNT) membrane is disclosed. Incorporation of the article in a filtration system is further disclosed. A method for oxidizing a surface of a CNT membrane, e.g., by applying a direct-current (DC) potential in/on said CNT membrane is further disclosed.
    Type: Application
    Filed: July 23, 2018
    Publication date: May 21, 2020
    Applicant: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Viatcheslav FREGER, Karen Adie TANKUS
  • Publication number: 20200151904
    Abstract: A method for estimating a plurality of camera, comprising using at least one processor executing a code for: extracting a plurality of image features of a plurality of landmarks from a plurality of images captured by at least one camera from at least one pose, the plurality of landmarks calibrated with respect to a certain coordinate system; identifying among the plurality of image features at least one image feature documented in at least some of the images; producing scale values of at least one common image feature by analyzing the at least some of the images; determining a plurality of estimated poses of the at least one camera with respect to the certain coordinate system by using the scale values in calculating a minimal re-projection error between the plurality of image features and a plurality of predicted image features; and outputting the plurality of estimated poses.
    Type: Application
    Filed: January 20, 2020
    Publication date: May 14, 2020
    Applicant: Technion Research & Development Foundation Limited
    Inventor: Vadim INDELMAN
  • Publication number: 20200148837
    Abstract: Doubly-crosslinked hydrogel polyHIPEs (DC-PHs), which exhibit rapid water absorption, enhanced mechanical properties, and shape memory behavior, are provided herein, as well as processes of producing the same and uses thereof. DC-PHs comprise a continuous HIPE-templated doubly-crosslinked hydrogel, formed from hydrogel-forming monomers, ligand-bearing monomers, and crosslinking monomers.
    Type: Application
    Filed: January 21, 2020
    Publication date: May 14, 2020
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Michael S. Silverstein, Tao Zhang
  • Patent number: 10646160
    Abstract: A method for locating a vessel, the method comprising illuminating at least a portion of the vessel with a background light having a substantially high susceptibility to absorption by particles in said portion of the vessel; detecting backscattered light from said illuminated portion of the vessel; reproducing an image from said backscattered light; and identifying dark regions within said reproduced image.
    Type: Grant
    Filed: January 17, 2013
    Date of Patent: May 12, 2020
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Dvir Yelin, Lior Golan
  • Patent number: 10639107
    Abstract: A system and method for ensuring safe and tolerable insertion of a needle into a subject's body according to a preplanned or continuously monitored sequence of insertion steps. The system comprises a gripping device for gripping the needle in order to perform robotic insertion steps, yet for releasing the grip between such insertion steps, until the next insertion step is initiated. Thereby, the robot has full control of the needle during insertion steps, but does not constrain the needle between insertions, such that movement of the subject can cause neither damage nor discomfort. The gripping and insertion steps may be coordinated to keep in synchronization with the subject's breathing cycles, such that the insertion steps may be performed in the same segment of each cycle of motion of the subject's chest. The gripper can either fully disconnect from the needle, or can partially disconnect but constrain motion within limits.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: May 5, 2020
    Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
    Inventors: Daniel Glozman, Gonen Daskal, Moshe Shoham, Michael Arad, Yoav Pinsky
  • Patent number: 10644304
    Abstract: Disclosed is a method for activating a surface of metals, such as self-passivated metals, and of metal-oxide dissolution, effected using a fluoroanion-containing composition. Also disclosed is an electrochemical cell utilizing an aluminum-containing anode material and a fluoroanion-containing electrolyte, characterized by high efficiency, low corrosion, and optionally mechanical or electrochemical rechargeability. Also disclosed is a process for fusing (welding, soldering etc.) a self-passivated metal at relatively low temperature and ambient atmosphere, and a method for electrodepositing a metal on a self-passivated metal using metal-oxide source.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: May 5, 2020
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Yair Ein-Eli, Danny Gelman, Boris Shvartsev, Alexander Kraytsberg
  • Publication number: 20200123338
    Abstract: Provided are compositions-of-matter comprising a continuous elastomeric matrix that is structurally-templated by an external phase of a high internal phase emulsion (HIPE), and a liquid dispersed and entrapped in the elastomeric matrix in a form of a plurality of discrete liquid-filled voids. Also provided are processes for obtaining said compositions-of-matter and uses thereof.
    Type: Application
    Filed: July 10, 2018
    Publication date: April 23, 2020
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Michael S. SILVERSTEIN, Sharon NIV
  • Patent number: 10606341
    Abstract: A system comprising: a camera configured to capture one or more images of a user's hand; and a computer configured to: receive the one or more captured images, apply a mapping function to the received one or more images, thereby yielding one or more coordinates associated with at least one feature of the user's hand, wherein the mapping function is derived from a set of labeled images that are produced by applying a machine learning algorithm to training data which comprises images of a trainer's hand, wherein the images are labeled with coordinates obtained from multiple magnetic sensors attached to the trainer's hand.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: March 31, 2020
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Aaron Wetzler, Ron Kimmel
  • Patent number: 10597635
    Abstract: Provided is an isolated population of human pluripotent stem cells comprising at least 50% human pluripotent stem cells characterized by an OCT4+/TRA1-60?/TRA1-81?/SSEA1+/SSEA4? expression signature, and novel methods of generating and maintaining same in a pluripotent, undifferentiated state a suspension culture devoid of cell clumps. Also provided are novel culture media, cell cultures and methods for culturing pluripotent stem cells in a suspension culture or a two-dimensional culture system while maintaining the cells in a proliferative, pluripotent and undifferentiated state. The novel culture media comprise interleukin 11 (IL11) and Ciliay Neurotrophic Factor (CNTF); bFGF at a concentration of at least 50 ng/ml and an IL6RIL6 chimera; or an animal contaminant-free serum replacement and an IL6RIL6 chimera. Also provided are methods for generating lineage-specific cells from the pluripotent stem cells.
    Type: Grant
    Filed: January 11, 2017
    Date of Patent: March 24, 2020
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Michal Amit, Joseph Itskovitz-Eldor
  • Patent number: 10590382
    Abstract: The present invention is of methods of establishing and propagating human embryonic stem cell lines using feeder cells-free, xeno-free culture systems and stem cells which are capable of being maintained in an undifferentiated, pluripotent and proliferative state in culture which is free of xeno contaminants and feeder cells.
    Type: Grant
    Filed: September 3, 2018
    Date of Patent: March 17, 2020
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Michal Amit, Joseph Itskovitz-Eldor
  • Publication number: 20200078386
    Abstract: A new class of pseudo-trisaccharide aminoglycosides having an alkyl group at the 5? position, exhibiting efficient stop codon mutation readthrough activity, low cytotoxicity and high selectivity towards eukaryotic translation systems are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders, as well as processes of preparing these aminoglycosides. The disclosed aminoglycosides can be represented by the general formula I: or a pharmaceutically acceptable salt thereof, wherein R1 is selected from the group consisting of alkyl, cycloalkyl and aryl; and all other variables and features are as described in the specification.
    Type: Application
    Filed: August 23, 2019
    Publication date: March 12, 2020
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Timor BAASOV, Dana ATIA-GLIKIN, Jeyakumar KANDASAMY, Valery BELAKHOV
  • Patent number: 10583273
    Abstract: A self-propelled device for locomotion through a lumen, comprising a set of serially arranged inflatable chambers, the end ones of which expand at least radially when inflated. Connecting passages provide fluid communication between each pair of adjacent chambers. A fluid source is attached to one of the end chambers. The connecting passages are such that the fluid inflates the chambers in a sequence, beginning with the chamber closest to the source, and ending with the chamber furthest from the source. The same sequence occurs when the chambers deflate, beginning with the chamber closest to the source, and ending with the chamber furthest from the source. The fluid source can either be a fluid supply tube, extending to a supply outside the lumen, or it can be built-in and carried by the device. The device can crawl either along the lumen wall or on an inserted guide wire.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: March 10, 2020
    Assignee: Technion Research & Development Foundation Ltd.
    Inventors: Moshe Shoham, Noam Hassidov, Daniel Glozman
  • Patent number: 10579390
    Abstract: A GPGPU-compatible architecture combines a coarse-grain reconfigurable fabric (CGRF) with a dynamic dataflow execution model to accelerate execution throughput of massively thread-parallel code. The CGRF distributes computation across a fabric of functional units. The compute operations are statically mapped to functional units, and an interconnect is configured to transfer values between functional units.
    Type: Grant
    Filed: December 3, 2017
    Date of Patent: March 3, 2020
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.
    Inventors: Yoav Etsion, Dani Voitsechov
  • Publication number: 20200055897
    Abstract: Peptoids are described herein, as well as compositions comprising an aqueous liquid and a peptoid soluble in the aqueous liquid. The peptoids comprise a plurality of N-substituted glycine residues and/or N-substituted ?-alanine residues, and at least one heteroalicyclic residue having a general formula: wherein W, X, Y1, Y2, Z1 and Z2 are as defined herein.
    Type: Application
    Filed: April 26, 2018
    Publication date: February 20, 2020
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Galia MAAYAN, Kaniraj Jeya PRATHAP
  • Patent number: 10561823
    Abstract: A self-propelled device for locomotion through a lumen, comprising a set of serially arranged inflatable chambers, adjacent chambers being fluidly connected, and a fluid source attached to one end of the set, such that the chambers inflate sequentially. The chambers are constructed of an elastic material and have a wall thickness and dimensions such that they have a characteristic with a non-monotonous relationship between the inflation pressure within the chamber and the chamber's inflated size. The characteristic is such that after an initial inflation pressure peak, the non-monotonous relationship adopts a negative slope, such that the volume of the chamber increases more rapidly than the volume of fluid flowing into it, and the inflation pressure of the chamber falls. This effect causes the chamber to inflate and anchor rapidly, while essentially slowing down the inflation of the succeeding chamber until inflation of the first is complete.
    Type: Grant
    Filed: July 24, 2016
    Date of Patent: February 18, 2020
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.
    Inventors: Daniel Glozman, Noam Hassidov, Moshe Shoham
  • Patent number: 10561707
    Abstract: The present invention relates, according to some embodiments, method of treating eye diseases, such as AMD by administering Semaphorin 3C (Sema3C) or a variant thereof having amino acid modifications at furin-like pro-protein convertase cleavage sites, rendering these sites resistant to cleavage.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: February 18, 2020
    Assignees: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD., RAMBAM MED-TECH LTD.
    Inventors: Shira Toledano, Ofra Kessler, Gera Neufeld, Yoreh Barak, Yelena Mumblat
  • Publication number: 20200046796
    Abstract: Provided are methods of selecting a treatment for a cancer in a subject in need thereof, by analyzing activity of Yes associated protein 1 (YAP) in cancer cells of the subject, and methods of treating cancer using a therapeutically effective amount of an caspase-3 inhibitor. Also provided are methods of improving wound healing by administering a wound healing effective amount of a caspase-3 activator.
    Type: Application
    Filed: October 13, 2017
    Publication date: February 13, 2020
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Yaron FUCHS, Yahav YOSEFZON, Despina SOTERIOU
  • Publication number: 20200040467
    Abstract: A system and method for generating hydrogen gas from an aqueous solution are disclosed herein. The system comprises a compartment with a working electrode for reducing water in response to an applied voltage to generate hydrogen and a redox-active electrode capable of reversibly undergoing oxidation and reduction. The system may further comprise a second compartment with a working electrode for generating oxygen and redox-active electrode electrically connectable to the redox-active electrode in the first compartment. The method comprises applying a voltage between a working electrode and a redox-active electrode of a system described herein and/or between comprising a working electrode of one compartment and a working electrode of a second compartment of a system described herein.
    Type: Application
    Filed: October 11, 2019
    Publication date: February 6, 2020
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Avner ROTHSCHILD, Gideon GRADER, Gennady SHTER, Avigail LANDMAN, Hen DOTAN
  • Publication number: 20200045509
    Abstract: A channel distribution system has a channel carrying content, and an interactive receiver which receives content and provides to a user. The interactive receiver has an interface to allow the user to interact with the content. The channel also includes a broadcast label superimposed on the content which invites the user to interact with the content. The label includes an interactive link with a digital instruction containing handling information for the interactive receiver device. The handling information tells the interactive receiver how to handle a user interaction coinciding with the label.
    Type: Application
    Filed: October 14, 2019
    Publication date: February 6, 2020
    Applicant: Technion Research & Development Foundation Limited
    Inventor: Oded SHMUELI
  • Patent number: 10548670
    Abstract: A robotic device for performing intracranial procedures, comprising a baseplate for mounting on the subject's skull and a rotatable base element rotating on the baseplate. The rotatable base element has a central opening through which a cannulated needle can protrude such that it can rotate around an axis perpendicular to the baseplate. This cannulated needle is robotically controlled to provide motion into and out of the subject's skull. A flexible needle is disposed coaxially within the cannulated needle, and it is controlled to move into and out of a non-axial aperture in the distal part of the cannulated needle. Coordinated control of the insertion motion of the cannulated and flexible needles, and rotation of the combined cannulated/flexible needle assembly enables access to be obtained to a volume of a region of the brain having lateral dimensions substantially larger than the width of the cannulated needle.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: February 4, 2020
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.
    Inventors: David Zarrouk, Moshe Shoham, Menashe Zaaroor, Hadas Ziso