Abstract: A method for managing distributed computing. The method comprises estimating, for each of a plurality of local computing nodes, a distribution of multidimensional values in a space. Each multidimensional value is calculated according to a plurality of locally monitored parameters. The method further includes calculating safe zones in the space where each safe zone is defined according to a respective estimated distribution under a global geometric constraint in the space and setting local geometric constraints for the local computing nodes according to the respective safe zones. Each local geometric constraint is defined such that a detection of at least one monitored multidimensional value violating it by a respective local computing node induces a communication event between the respective local computing node and one or more central computing nodes.

Abstract: A method for locating a vessel, the method comprising illuminating at least a portion of the vessel with a background light having a substantially high susceptibility to absorption by particles in said portion of the vessel; detecting backscattered light from said illuminated portion of the vessel; reproducing an image from said backscattered light; and identifying dark regions within said reproduced image.

Abstract: In a data storage and retrieval system wherein data is stored and retrieved in pages, said data comprising connected nodes arranged such that each page stores only complete nodes, said connected nodes being connected via a plurality of overlapping tree structures, a method of minimizing page retrieval in the face of changing relationships between nodes comprising: selecting at least two of said overlapping tree structures; incrementally adjusting a page node structure dynamically based on real time workload, separately according to each selected tree structure, to form modified partitions for each tree structure, each modified partition being so as to minimize page faults; for each modified partition calculating a modification gain to indicate which partition has provided a greater minimization of page faults; and selecting the tree structure and modified partition corresponding to the best modification gain.

Abstract: A method for estimating the location and orientation of a mobile robot with respect to landmarks whose positions are given using a sensor for measuring bearings of the landmarks with respect to the robot, where bias errors are present. The method comprises using the sensor to obtain bearings the landmarks. The location and orientation of the robot with respect to the landmarks is estimated, based on the measured bearings, and bias errors associated with the measured bearings are corrected to obtain corrected bearings. A correction function is used to finds the minimal sum of squared errors between measured bearings and the corrected bearings. The location and the orientation of the robot is determined to be where the sum of squared errors between measured bearings and the corrected bearings is minimal.

Abstract: A method of generating pancreatic progenitor cells is disclosed. The method comprises: (a) differentiating stem cells under conditions such that at least a portion of the cells express glucose transporter 2 (GLUT2) so as to generate GLUT2-expressing cells; and (b) enriching for the GLUT2-expressing cells so as to generate a population of GLUT2 enriched cells, wherein at least 80% of the population of GLUT2 enriched cells express GLUT2, thereby generating pancreatic progenitor cells. Isolated populations of cells generated according to the method, pharmaceutical compositions comprising same and uses thereof are also disclosed.

Abstract: A semiconductor device which produces at least 1 W/m2 two photon emission power per area, when operating at one or more temperatures greater than 20 K.

Abstract: Polymeric foams and elastomer/hydrogel bicontinuous composite structures derived from high internal phase emulsions and possessing shape-memory characteristics are disclosed, as well as processes for forming the same and uses thereof in, for example, manufacturing of various articles.

Abstract: A porous scaffold is disclosed, the porous scaffold comprising electrospun polymeric nanofibers, wherein an average diameter of a pore of the porous scaffold is about 300 ?m is disclosed. An average diameter of the polymeric nanofibers ranges from about 100 to 400 nm. The scaffold may comprise a plurality of particles, the particles being greater than about 1 ?m in diameter. Methods of fabricating scaffolds, methods for generating tissue and methods of using scaffolds for tissue reconstruction are also disclosed.

Abstract: A method of evaluating a semantic relatedness of terms. The method comprises providing a plurality of text segments, calculating, using a processor, a plurality of weights each for another of the plurality of text segments, calculating a prevalence of a co-appearance of each of a plurality of pairs of terms in the plurality of text segments, and evaluating a semantic relatedness between members of each the pair according to a combination of a respective the prevalence and a weight of each of the plurality of text segments wherein a co-appearance of the pair occurs.

Abstract: A new class of pseudo-trisaccharide aminoglycosides having an alkyl group at the 5? position, exhibiting efficient stop codon mutation readthrough activity, low cytotoxicity and high selectivity towards eukaryotic translation systems are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders, as well as processes of preparing these aminoglycosides. The disclosed aminoglycosides can be represented by the general formula I: or a pharmaceutically acceptable salt thereof, wherein R1 is selected from the group consisting of alkyl, cycloalkyl and aryl; and all other variables and features are as described in the specification.

Abstract: A method for error detection includes storing in an associative memory multiple data entries, each data entry including a data item together with one or more check symbols computed with respect to the data item. A predetermined sequence of search keys is applied to the memory, thereby causing the memory to generate, in parallel, match results with respect to the data entries. The match results are processed in order to identify an error in at least one of the data entries.

Abstract: An optical device includes a substrate, a metallic layer, a dielectric filling and a light collection element. The substrate has first and second opposite surfaces, and has a funnel-shaped cavity between a first aperture on the first surface and a second aperture on the second surface. The metallic layer covers an inner wall of the funnel-shaped cavity. The dielectric filling is disposed over the metallic layer and fills the funnel-shaped cavity. The light collection element is coupled to the second aperture, and is configured to collect light that impinges on the first aperture and is directed to the second aperture by the metallic layer and dielectric filling.

Abstract: An apparatus arranged for examining particles, comprising: a cartridge having at least one microchannel, a viscoelastic fluid flowing in the microchannel, the fluid comprising a suspension of particles, thereby effecting alignment of the particles in at least one-dimensional array parallel to the fluid flow, and an optical magnifying means generating an image of the particles in the microchannel.

Abstract: Articles of manufacturing comprising electrospun elements having continuous or stepwise gradients of porosity, average pore size, weight per volume and/or of agents for promoting cell colonization, differentiation, extravasation and/or migration are provided. Also provided are methods of manufacturing and using same for guiding tissue regeneration.

Abstract: A temporal focusing system is disclosed. The temporal focusing system is configured for receiving a light beam pulse and for controlling a temporal profile of the pulse to form an intensity peak at a focal plane. The temporal focusing system has a prismatic optical element configured for receiving the light beam pulse from an input direction parallel to or collinear with the optical axis of the temporal focusing system and diffracting the light beam pulse along the input direction.

Abstract: A method of separating a mixture of a plurality of molecular analytes having different isoelectric points (pIs). The method comprises placing a solution containing a mixture of a plurality of molecular analytes in a separation volume, generating a pH profile having a plurality of pH zones across an axis of the separation volume, and adjusting a profile of the pH profile to induce a migration of a first molecular analyte along the axis apart from a second molecular analyte. The first and second molecular analytes having different pIs.

Abstract: An apparatus includes an optical ring resonator, first and second optical couplers, and control circuitry. The first optical coupler is configured to modulate an input optical signal traversing an optical waveguide, by tuning cross-coupling of energy between the optical waveguide and the ring resonator with a first variable coupling coefficient. The second optical coupler is configured to tune cross-coupling of energy between the ring resonator and an auxiliary optical signal, different from the input optical signal, with a second variable coupling coefficient. The control circuitry is configured to modulate the first coupling coefficient with a first control signal so as to modulate the input optical signal, and to modulate the second coupling coefficient with a second control signal, so as to retain a constant electrical-field complex envelope in the ring resonator.

Abstract: A neural network is disclosed. The neural network comprises a plurality of optogenetically modified neural cells being three-dimensionally distributed in a hydrogel medium and being disconnected from any solid support having a shear modulus above 1 GPa.

Abstract: A cell culture comprising human foreskin cells, the human foreskin cells being capable of maintaining stem cells in an undifferentiated state when co-cultured therewith.

Abstract: A method for signal processing includes accepting an analog signal, which consists of a sequence of pulses confined to a finite time interval. The analog signal is sampled at a sampling rate that is lower than a Nyquist rate of the analog signal and with samples taken at sample times that are independent of respective pulse shapes of the pulses and respective time positions of the pulses in the time interval. The sampled analog signal is processed.