Patents Assigned to Technische Universität München
  • Patent number: 11709471
    Abstract: A method includes: receiving a mathematical model of a control system, with state variables and control parameters; discretizing at least a part of a space to obtain a set of tuples; determining for each tuple at least one successor state; obtaining an initial winning set of tuples; determining an updated winning set of tuples, including comparing the at least one successor state with the initial winning set of tuples, where the comparison is distributed over available processing elements by choosing one processing element from the available processing elements for each tuple to perform the comparison and where the available processing elements are used simultaneously at least in part; repeating the determination of the updated winning set of tuples to obtain a new updated winning set of tuples if a convergence measure does not meet a criterion, and constructing a controller for the control system from the new updated winning set.
    Type: Grant
    Filed: October 2, 2019
    Date of Patent: July 25, 2023
    Assignee: Technische Universität München
    Inventors: Mahmoud Khaled Mohamed Mahmoud, Majid Zamani
  • Patent number: 11685810
    Abstract: A catalyst/initiator system that can be used for polymerizing ?-butyrolactone is described. The catalyst/initiator system includes a rare earth metal, a chiral ligand, at least one nucleophilic ligand, optionally at least one solvent ligand, and optionally an alkali based co-catalyst. The chiral ligand can have the structure of Formula A, as shown below: wherein Y represents rare earth metal Yttrium, Ph represents Phenyl radical and thf represents tetrahydrofuran solvent ligand.
    Type: Grant
    Filed: June 1, 2022
    Date of Patent: June 27, 2023
    Assignee: Technische Universität München
    Inventors: Friederike Adams, Bernhard Rieger
  • Publication number: 20230195906
    Abstract: An information processing device, wherein the information processing device includes circuitry configured to: copy, in response to an instruction for play back of a content, encrypted content data; decrypt the copied encrypted content data for obtaining the content data representing the content; and apply a data protection algorithm on the content data to generate protected content data representing protected content, wherein the protected content is played back.
    Type: Application
    Filed: December 8, 2022
    Publication date: June 22, 2023
    Applicants: Sony Semiconductor Solutions Corporation, Technische Universität München - TUM
    Inventors: Shivangi ANEJA, Lev MARKHASIN, Matthias NIEßNER, Stefan UHLICH, Bi WANG
  • Publication number: 20230173113
    Abstract: The invention provides conjugates of cyclic peptides as ligands for cellular surface receptors, in particular, as ligands for ?v?6-integrin. The conjugates further contain effector moieties and are suitable for use as therapeutic agent, diagnostic agent, agent for imaging, targeting moiety and as biomolecular research tool. The invention specifically relates to the use of conjugates with signalling moieties or radionuclides for in-vivo addressing of ?v?6-integrin.
    Type: Application
    Filed: March 12, 2021
    Publication date: June 8, 2023
    Applicant: Technische Universität München
    Inventors: Johannes Notni, Neil Quigley, Katja Steiger
  • Patent number: 11578321
    Abstract: The present invention discloses a method for assessing the capacity of a substance to treat or prevent hepadnavirus infection. A reporter virus carrying genetic information for a first fragment of a recombinase and a reporter cell expressing a second fragment of the recombinase are used. When the reporter virus infects the reporter cell, the two fragments of the recombinase associate and excise a stop cassette that is flanked by two recombination sites and blocks the expression of a reporter gene. Accordingly, the present invention relates to a method of assessing the capacity of a substance to treat or prevent hepadnavirus infection, a hepadnavirus comprising a nucleic acid encoding a first fragment of a recombinase and a mammalian hepatocyte or hepatoma cell comprising a nucleic acid encoding a second fragment of a recombinase and a nucleic acid comprising a stop cassette flanked by two recombination sites fused to a reporter gene.
    Type: Grant
    Filed: August 15, 2019
    Date of Patent: February 14, 2023
    Assignees: Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Technische Universität München
    Inventors: Wen-Min Chou, Ulrike Protzer-Knolle, Martin Mueck-Haeusl, Chunkyu Ko, Jochen Wettengel
  • Patent number: 11497819
    Abstract: The present invention relates to compounds which bind and/or inhibit prostate-specific membrane antigen (PSMA) comprising at least one group electron dense substituent (EDS), and at least one moiety which is amenable to radiolabeling; and therapeutic and diagnostic uses thereof.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: November 15, 2022
    Assignee: Technische Universität München
    Inventors: Hans-Jurgen Wester, Alexander Schmidt, Mara Parzinger
  • Patent number: 11459423
    Abstract: A process for polymerizing ?-butyrolactone that includes contacting racemic ?-butyrolactone or an enantiomer thereof with a catalyst/initiator system which includes a rare earth metal, a chiral ligand, at least one nucleophilic ligand, optionally at least one solvent ligand, and optionally an alkali based co-catalyst. The chiral ligand is an enantiomer of a unit of formula I Each Rz independently is substituted or unsubstituted linear C1-C20 alkyl, or substituted or unsubstituted branched, or cyclic C3-C20 alkyl, substituted or unsubstituted C6-C20 aryl, substituted or unsubstituted C5-C20 heteroaryl, or halogen. Each Ra independently is H, Me+, (MeZ)+, wherein Z is a charge equalizing anion, or wherein two Ra together are alkaline earth metal, wherein Me+ is alkali metal or alkaline earth metal.
    Type: Grant
    Filed: November 21, 2018
    Date of Patent: October 4, 2022
    Assignee: Technische Universität München
    Inventors: Friederike Adams, Bernhard Rieger
  • Patent number: 11422032
    Abstract: Disclosed herein is a device (100) for multicolor optical imaging of a sample (102) with wavelength-dependent optical path length enhancement, the device (100) comprising an optical resonator (106) for enhancing an optical path length, wherein the optical resonator (106) has a first finesse at a first wavelength and a second finesse at a second wavelength; a sample holder (104) for mounting the sample (102) in the optical resonator (106), wherein the sample holder (104) is configured to hold the sample (102) such that an optical axis (112) of the optical resonator (106) intersects with the sample (102);a first imaging system (114) for imaging the sample (102) at the first wavelength with a first imaging technique, and a second imaging system (126) for imaging the sample (102) at the second wavelength with a second imaging technique, wherein the second wavelength is different from the first wavelength; wherein the first finesse and the second finesse are chosen such that the optical resonator (106) enhances a
    Type: Grant
    Filed: October 25, 2019
    Date of Patent: August 23, 2022
    Assignee: Technische Universität München
    Inventors: Hristo Iglev, Oliver Hayden, Reinhard Kienberger, Markus Wurzer, Albert Schletter, Johann Riemensberger
  • Patent number: 11413360
    Abstract: The present invention relates to a ligand-SIFA-chelator conjugate, comprising, within in a single molecule three separate moieties: (a) one or more ligands which are capable of binding to a disease-relevant target molecule, (b) a silicon-fluoride acceptor (SIFA) moiety which comprises a covalent bond between a silicon atom and a fluorine atom, and (c) one or more chelating groups, optionally containing a chelated nonradioactive or radioactive cation.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: August 16, 2022
    Assignees: Technische Universität München, Technische Universität München—Klinikum Rechts der Isar
    Inventors: Alexander Josef Wurzer, Hans-Jürgen Wester, Matthias Johannes Eiber
  • Patent number: 11398726
    Abstract: A method for identifying the switch topology of multiple energy storage module connected in parallel and/or in series, which respectively have at least one energy storage element, each module has a switch element for selectively activating and deactivating the module and a unique identifier, wherein each module is assigned to a module string in that a total current flowing across the switch topology is checked, and individual modules are activated successively via the switch element until the total current is detectable.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: July 26, 2022
    Assignee: Technische Universität München
    Inventor: Thomas Zimmermann
  • Patent number: 11352254
    Abstract: A molecular machine comprising a movement part (2) including a first molecular element (4), a second molecular element (5), and a linking element (6) for constraining a relative movement of the first molecular element (4) and the second molecular element (5), and a control part configured to generate an electrical field around the movement part (2), wherein the first molecular element (4) is fixed relative to the control part, wherein the second molecular element (5) is movable relative to the first molecular element (4) in at least one degree of freedom, and wherein the second molecular element (5) is electrically charged such that the second molecular element (5) aligns to said electrical field.
    Type: Grant
    Filed: April 6, 2018
    Date of Patent: June 7, 2022
    Assignee: Technische Universität München
    Inventors: Enzo Kopperger, Jonathan List, Friedrich C. Simmel
  • Patent number: 11332498
    Abstract: Disclosed are compounds represented by the following general formula (I): Cyclo-(Arg-Gly-Asp-X1-X2-X3-X4-X5) (I) wherein the variables groups X1 to X5 have the following meanings X1: Leu, Ile, Nle, Val, Tyr, Phe; X2: D-amino acid such as D-Pro, N-Me-D-Phe; X3: Pro, N-Me-amino acid such as N-Me-Lys, N-Me-Lys(Ac); Pro-Rx3, N-Me-Lys-Rx4; X4: Gly, Ala, Ser, Thr; X5: Leu, Ala, Tyr, His, Ile, Nle, Val, Phe wherein Pro-Rx3 represents a proline residue that carries at the C-3, C-4 or C-5 carbon atom and preferably the C-4 carbon atom a functional group selected from —NH2, —OH, —NH—Ac, —NH-hexyne, and wherein Lys-Rx4 represents a lysine residue, wherein the ?-amino nitrogen atom carries a group of the formula -L4-R4, wherein L4 is selected from the group consisting of covalent bond, —C(O)—, and —C(O)—O—, . . .
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: May 17, 2022
    Assignee: Technische Universitat Munchen
    Inventors: Horst Kessler, Tobias Kapp, Florian Reichart, Oleg Maltsev
  • Publication number: 20220096669
    Abstract: A ligand-SiFA conjugate compound represented by formula (1) wherein: RL is a ligand moiety which is capable of binding to prostate-specific membrane antigen (PSMA); RSiFA is a silicon-fluoride acceptor (SiFA) moiety which can be labeled with 18F or which is labeled with 18F; L is a linking moiety; RH is a hydrophilic moiety which comprises (i) a linear or branched sequence of 2 to 10 hydrophilic amino acid units AH, each of which is independently derived from a natural or non-natural amino acid carrying a hydrophilic side chain, and optionally one amino acid unit AN derived from a natural or non-natural amino acid which is devoid of a hydrophilic side chain, wherein the hydrophilic amino acid units and, if present, the unit AN, are bound to each other via a direct covalent bond or via a coupling unit; and which optionally further comprises (ii) one or more hydrophilic residues RT, each of which may be bound to an amino group, a carboxylic acid group, or to a hydrophilic side chain of an amino acid unit; or a
    Type: Application
    Filed: January 29, 2020
    Publication date: March 31, 2022
    Applicant: Technische Universität München
    Inventors: Daniel DI CARLO, Hans-Jürgen WESTER
  • Patent number: 11224949
    Abstract: The invention relates to a speed-changing shearing or forming active element insert which is designed to be detachably connected to an active element receptacle of a machine tool, the speed-changing shearing or forming active element insert having a speed-changing unit which is in the form of a hydraulic force/distance transducer, the force/distance transducer comprising a housing, the housing interior of which is supplied with a hydraulic fluid, and the force/distance transducer comprising a first piston which is in oo contact with the hydraulic fluid via one piston end and a second piston which is in contact with the hydraulic fluid via one piston end and the cross-sectional area of which is smaller than the cross-sectional area of the first piston. The invention also relates to the use of the speed-changing changing shearing or forming active element insert in a machine tool.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: January 18, 2022
    Assignee: Technische Universität München
    Inventors: Tim Benkert, Martin Feistle, Thomas Kopp, Roland Golle
  • Patent number: 11108411
    Abstract: The present application concerns an encoding device comprising a FC 11 configured to generate m FC-output-bit-sequences by executing m polar encoding steps upon m FC-input-bit-sequences that comprise frozen and unfrozen bits, wherein m?2. In an i-th polar encoding step of the m polar encoding steps at least one frozen bit is based on at least one unfrozen bit. The present application also concerns a decoding device comprising a processor configured to decode successively a polar-coded-bitstream comprising m-polar decoding steps, wherein m?2. In an i-th polar decoding step of the m polar decoding steps at least one frozen bit is based on at least one unfrozen bit. Further, the present application concerns also correspondingly arranged encoding and decoding methods.
    Type: Grant
    Filed: October 18, 2019
    Date of Patent: August 31, 2021
    Assignees: Huawei Technologies Duesseldorf GmbH, Technische Universität München
    Inventors: Tobias Prinz, Peihong Yuan, Georg Boecherer, Gerhard Kramer, Onurcan Iscan, Ronald Boehnke, Wen Xu
  • Patent number: 11097858
    Abstract: Embodiments described herein include a satellite cover panel for covering a satellite, particularly a payload bay of a satellite comprising an energy storage module, at least one energy generating module defining, at least partially, a first outer surface of the satellite cover panel, and a logic board defining, at least partially, a second outer surface of the satellite cover panel, wherein the first outer surface and the second outer surface face away from each other and from the energy storage module.
    Type: Grant
    Filed: July 23, 2018
    Date of Patent: August 24, 2021
    Assignee: Technische Universität München
    Inventors: Thomas Grübler, Martin Langer
  • Publication number: 20210234618
    Abstract: Encoders and decoders for encoding and decoding data according to a coding scheme. The encoder converts N bits of input data into M voltage signals for transmission over M parallel wires to a decoder having one or two decoding stages that recover the N bits of data from the M voltage signals. The coding scheme is an N-bit, M-wire PAM-Q code in which each voltage signal wi has one of Q voltage levels I1-IQ, where I1<I2< . . . <IQ, and the different sets of M voltage signals for the different N-bit input values are permutations of a single set of M voltage signals. The decoder has a comparator stage. For the decoder having one other decoding stage, the other decoding stage is a computation stage or a logic stage that is before or after the comparator stage.
    Type: Application
    Filed: January 24, 2020
    Publication date: July 29, 2021
    Applicants: Nokia Solutions and Networks Oy, Technische Universität München
    Inventors: Ariel Leonardo Vera Villarroel, Gerhard Kramer
  • Patent number: 11045090
    Abstract: A medical imaging apparatus for combined X-ray and optical visualization is provided. It comprises: an X-ray detector positioned above a patient; an X-ray source positioned below a patient; a control device; and a camera setup adapted to deliver an optical stereoscopic or 3D image. Thereby, the camera setup is positioned adjacent to the X-ray detector above the patient, and the control device is adapted to calculate an optical 2D image or a 3D surface from the data delivered by the camera setup, that optical 2D image or 3D surface having a virtual viewpoint similar to the viewpoint of the X-ray source. It is further adapted to superimpose an X-ray image acquired by the X-ray detector and the optical 2D image or 3D surface in order to achieve an augmented optical/X-ray image.
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: June 29, 2021
    Assignee: Technische Universität München
    Inventor: Nassir Navab
  • Patent number: 11038525
    Abstract: A method (C) for converting a data signal (U), comprising (i) providing an input symbol stream (B) representative of the data signal (U), (ii) demultiplexing (DMX) the input symbol stream (B) to consecutively decompose the input symbol stream (B) into a number m of decomposed partial symbol streams (B_1, . . . , B_m), (iii) applying on each of the decomposed partial symbol streams (B_1, . . . , B_m) an assigned distribution matching process (DM_1, . . . , DM_m), thereby generating and outputting for each decomposed partial symbol stream (B_1, . . . , B_m) a respective pre-sequence (bn_1, . . . , bn_m) or n_j symbols as an intermediate output symbol sequence, and (iv) supplying the pre-sequences (bn_1, . . . , bn_m) to at least one symbol mapping process (BM) to generate and output a signal representative for a final output symbol sequence (S) as a converted data signal. Each of the distribution matching processes (DM_1, . . .
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: June 15, 2021
    Assignee: Technische Universität München
    Inventors: Georg Böcherer, Patrick Schulte, Fabian Steiner
  • Patent number: 10959088
    Abstract: A communication method (S) for communication between mobile units (10, 20), and in particular between vehicles, in which information transmitted between the mobile units (10, 20) is encoded on the transmitter side by means of an encoder (12-1, 22-1) and is decoded on the receiver side by means of a decoder (12-2, 22-2), and the mobile units (10, 20) are synchronized in communication (S3) with an external interface unit (30) outside the mobile units (10, 20) prior to communication (S5) with one another in that a codebook (Cj) defining or specifying an encoder (12-1, 22-1) and/or a decoder (12-2, 22-2) is determined (S2) by the external interface unit (30) and is communicated (S3) to the mobile units (10, 20).
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: March 23, 2021
    Assignees: Technische Universität München, Bayerische Motoren Werke Aktiengesellschaft
    Inventors: Holger Boche, Christian Arendt