Patents Assigned to Technische Universität München
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Patent number: 11709471Abstract: A method includes: receiving a mathematical model of a control system, with state variables and control parameters; discretizing at least a part of a space to obtain a set of tuples; determining for each tuple at least one successor state; obtaining an initial winning set of tuples; determining an updated winning set of tuples, including comparing the at least one successor state with the initial winning set of tuples, where the comparison is distributed over available processing elements by choosing one processing element from the available processing elements for each tuple to perform the comparison and where the available processing elements are used simultaneously at least in part; repeating the determination of the updated winning set of tuples to obtain a new updated winning set of tuples if a convergence measure does not meet a criterion, and constructing a controller for the control system from the new updated winning set.Type: GrantFiled: October 2, 2019Date of Patent: July 25, 2023Assignee: Technische Universität MünchenInventors: Mahmoud Khaled Mohamed Mahmoud, Majid Zamani
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Patent number: 11685810Abstract: A catalyst/initiator system that can be used for polymerizing ?-butyrolactone is described. The catalyst/initiator system includes a rare earth metal, a chiral ligand, at least one nucleophilic ligand, optionally at least one solvent ligand, and optionally an alkali based co-catalyst. The chiral ligand can have the structure of Formula A, as shown below: wherein Y represents rare earth metal Yttrium, Ph represents Phenyl radical and thf represents tetrahydrofuran solvent ligand.Type: GrantFiled: June 1, 2022Date of Patent: June 27, 2023Assignee: Technische Universität MünchenInventors: Friederike Adams, Bernhard Rieger
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Publication number: 20230195906Abstract: An information processing device, wherein the information processing device includes circuitry configured to: copy, in response to an instruction for play back of a content, encrypted content data; decrypt the copied encrypted content data for obtaining the content data representing the content; and apply a data protection algorithm on the content data to generate protected content data representing protected content, wherein the protected content is played back.Type: ApplicationFiled: December 8, 2022Publication date: June 22, 2023Applicants: Sony Semiconductor Solutions Corporation, Technische Universität München - TUMInventors: Shivangi ANEJA, Lev MARKHASIN, Matthias NIEßNER, Stefan UHLICH, Bi WANG
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Publication number: 20230173113Abstract: The invention provides conjugates of cyclic peptides as ligands for cellular surface receptors, in particular, as ligands for ?v?6-integrin. The conjugates further contain effector moieties and are suitable for use as therapeutic agent, diagnostic agent, agent for imaging, targeting moiety and as biomolecular research tool. The invention specifically relates to the use of conjugates with signalling moieties or radionuclides for in-vivo addressing of ?v?6-integrin.Type: ApplicationFiled: March 12, 2021Publication date: June 8, 2023Applicant: Technische Universität MünchenInventors: Johannes Notni, Neil Quigley, Katja Steiger
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Patent number: 11578321Abstract: The present invention discloses a method for assessing the capacity of a substance to treat or prevent hepadnavirus infection. A reporter virus carrying genetic information for a first fragment of a recombinase and a reporter cell expressing a second fragment of the recombinase are used. When the reporter virus infects the reporter cell, the two fragments of the recombinase associate and excise a stop cassette that is flanked by two recombination sites and blocks the expression of a reporter gene. Accordingly, the present invention relates to a method of assessing the capacity of a substance to treat or prevent hepadnavirus infection, a hepadnavirus comprising a nucleic acid encoding a first fragment of a recombinase and a mammalian hepatocyte or hepatoma cell comprising a nucleic acid encoding a second fragment of a recombinase and a nucleic acid comprising a stop cassette flanked by two recombination sites fused to a reporter gene.Type: GrantFiled: August 15, 2019Date of Patent: February 14, 2023Assignees: Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Technische Universität MünchenInventors: Wen-Min Chou, Ulrike Protzer-Knolle, Martin Mueck-Haeusl, Chunkyu Ko, Jochen Wettengel
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Patent number: 11497819Abstract: The present invention relates to compounds which bind and/or inhibit prostate-specific membrane antigen (PSMA) comprising at least one group electron dense substituent (EDS), and at least one moiety which is amenable to radiolabeling; and therapeutic and diagnostic uses thereof.Type: GrantFiled: December 11, 2018Date of Patent: November 15, 2022Assignee: Technische Universität MünchenInventors: Hans-Jurgen Wester, Alexander Schmidt, Mara Parzinger
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Patent number: 11459423Abstract: A process for polymerizing ?-butyrolactone that includes contacting racemic ?-butyrolactone or an enantiomer thereof with a catalyst/initiator system which includes a rare earth metal, a chiral ligand, at least one nucleophilic ligand, optionally at least one solvent ligand, and optionally an alkali based co-catalyst. The chiral ligand is an enantiomer of a unit of formula I Each Rz independently is substituted or unsubstituted linear C1-C20 alkyl, or substituted or unsubstituted branched, or cyclic C3-C20 alkyl, substituted or unsubstituted C6-C20 aryl, substituted or unsubstituted C5-C20 heteroaryl, or halogen. Each Ra independently is H, Me+, (MeZ)+, wherein Z is a charge equalizing anion, or wherein two Ra together are alkaline earth metal, wherein Me+ is alkali metal or alkaline earth metal.Type: GrantFiled: November 21, 2018Date of Patent: October 4, 2022Assignee: Technische Universität MünchenInventors: Friederike Adams, Bernhard Rieger
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Patent number: 11422032Abstract: Disclosed herein is a device (100) for multicolor optical imaging of a sample (102) with wavelength-dependent optical path length enhancement, the device (100) comprising an optical resonator (106) for enhancing an optical path length, wherein the optical resonator (106) has a first finesse at a first wavelength and a second finesse at a second wavelength; a sample holder (104) for mounting the sample (102) in the optical resonator (106), wherein the sample holder (104) is configured to hold the sample (102) such that an optical axis (112) of the optical resonator (106) intersects with the sample (102);a first imaging system (114) for imaging the sample (102) at the first wavelength with a first imaging technique, and a second imaging system (126) for imaging the sample (102) at the second wavelength with a second imaging technique, wherein the second wavelength is different from the first wavelength; wherein the first finesse and the second finesse are chosen such that the optical resonator (106) enhances aType: GrantFiled: October 25, 2019Date of Patent: August 23, 2022Assignee: Technische Universität MünchenInventors: Hristo Iglev, Oliver Hayden, Reinhard Kienberger, Markus Wurzer, Albert Schletter, Johann Riemensberger
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Patent number: 11413360Abstract: The present invention relates to a ligand-SIFA-chelator conjugate, comprising, within in a single molecule three separate moieties: (a) one or more ligands which are capable of binding to a disease-relevant target molecule, (b) a silicon-fluoride acceptor (SIFA) moiety which comprises a covalent bond between a silicon atom and a fluorine atom, and (c) one or more chelating groups, optionally containing a chelated nonradioactive or radioactive cation.Type: GrantFiled: July 30, 2018Date of Patent: August 16, 2022Assignees: Technische Universität München, Technische Universität München—Klinikum Rechts der IsarInventors: Alexander Josef Wurzer, Hans-Jürgen Wester, Matthias Johannes Eiber
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Patent number: 11398726Abstract: A method for identifying the switch topology of multiple energy storage module connected in parallel and/or in series, which respectively have at least one energy storage element, each module has a switch element for selectively activating and deactivating the module and a unique identifier, wherein each module is assigned to a module string in that a total current flowing across the switch topology is checked, and individual modules are activated successively via the switch element until the total current is detectable.Type: GrantFiled: July 10, 2018Date of Patent: July 26, 2022Assignee: Technische Universität MünchenInventor: Thomas Zimmermann
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Patent number: 11352254Abstract: A molecular machine comprising a movement part (2) including a first molecular element (4), a second molecular element (5), and a linking element (6) for constraining a relative movement of the first molecular element (4) and the second molecular element (5), and a control part configured to generate an electrical field around the movement part (2), wherein the first molecular element (4) is fixed relative to the control part, wherein the second molecular element (5) is movable relative to the first molecular element (4) in at least one degree of freedom, and wherein the second molecular element (5) is electrically charged such that the second molecular element (5) aligns to said electrical field.Type: GrantFiled: April 6, 2018Date of Patent: June 7, 2022Assignee: Technische Universität MünchenInventors: Enzo Kopperger, Jonathan List, Friedrich C. Simmel
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Patent number: 11332498Abstract: Disclosed are compounds represented by the following general formula (I): Cyclo-(Arg-Gly-Asp-X1-X2-X3-X4-X5) (I) wherein the variables groups X1 to X5 have the following meanings X1: Leu, Ile, Nle, Val, Tyr, Phe; X2: D-amino acid such as D-Pro, N-Me-D-Phe; X3: Pro, N-Me-amino acid such as N-Me-Lys, N-Me-Lys(Ac); Pro-Rx3, N-Me-Lys-Rx4; X4: Gly, Ala, Ser, Thr; X5: Leu, Ala, Tyr, His, Ile, Nle, Val, Phe wherein Pro-Rx3 represents a proline residue that carries at the C-3, C-4 or C-5 carbon atom and preferably the C-4 carbon atom a functional group selected from —NH2, —OH, —NH—Ac, —NH-hexyne, and wherein Lys-Rx4 represents a lysine residue, wherein the ?-amino nitrogen atom carries a group of the formula -L4-R4, wherein L4 is selected from the group consisting of covalent bond, —C(O)—, and —C(O)—O—, . . .Type: GrantFiled: March 16, 2018Date of Patent: May 17, 2022Assignee: Technische Universitat MunchenInventors: Horst Kessler, Tobias Kapp, Florian Reichart, Oleg Maltsev
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Publication number: 20220096669Abstract: A ligand-SiFA conjugate compound represented by formula (1) wherein: RL is a ligand moiety which is capable of binding to prostate-specific membrane antigen (PSMA); RSiFA is a silicon-fluoride acceptor (SiFA) moiety which can be labeled with 18F or which is labeled with 18F; L is a linking moiety; RH is a hydrophilic moiety which comprises (i) a linear or branched sequence of 2 to 10 hydrophilic amino acid units AH, each of which is independently derived from a natural or non-natural amino acid carrying a hydrophilic side chain, and optionally one amino acid unit AN derived from a natural or non-natural amino acid which is devoid of a hydrophilic side chain, wherein the hydrophilic amino acid units and, if present, the unit AN, are bound to each other via a direct covalent bond or via a coupling unit; and which optionally further comprises (ii) one or more hydrophilic residues RT, each of which may be bound to an amino group, a carboxylic acid group, or to a hydrophilic side chain of an amino acid unit; or aType: ApplicationFiled: January 29, 2020Publication date: March 31, 2022Applicant: Technische Universität MünchenInventors: Daniel DI CARLO, Hans-Jürgen WESTER
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Patent number: 11224949Abstract: The invention relates to a speed-changing shearing or forming active element insert which is designed to be detachably connected to an active element receptacle of a machine tool, the speed-changing shearing or forming active element insert having a speed-changing unit which is in the form of a hydraulic force/distance transducer, the force/distance transducer comprising a housing, the housing interior of which is supplied with a hydraulic fluid, and the force/distance transducer comprising a first piston which is in oo contact with the hydraulic fluid via one piston end and a second piston which is in contact with the hydraulic fluid via one piston end and the cross-sectional area of which is smaller than the cross-sectional area of the first piston. The invention also relates to the use of the speed-changing changing shearing or forming active element insert in a machine tool.Type: GrantFiled: July 26, 2017Date of Patent: January 18, 2022Assignee: Technische Universität MünchenInventors: Tim Benkert, Martin Feistle, Thomas Kopp, Roland Golle
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Patent number: 11108411Abstract: The present application concerns an encoding device comprising a FC 11 configured to generate m FC-output-bit-sequences by executing m polar encoding steps upon m FC-input-bit-sequences that comprise frozen and unfrozen bits, wherein m?2. In an i-th polar encoding step of the m polar encoding steps at least one frozen bit is based on at least one unfrozen bit. The present application also concerns a decoding device comprising a processor configured to decode successively a polar-coded-bitstream comprising m-polar decoding steps, wherein m?2. In an i-th polar decoding step of the m polar decoding steps at least one frozen bit is based on at least one unfrozen bit. Further, the present application concerns also correspondingly arranged encoding and decoding methods.Type: GrantFiled: October 18, 2019Date of Patent: August 31, 2021Assignees: Huawei Technologies Duesseldorf GmbH, Technische Universität MünchenInventors: Tobias Prinz, Peihong Yuan, Georg Boecherer, Gerhard Kramer, Onurcan Iscan, Ronald Boehnke, Wen Xu
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Patent number: 11097858Abstract: Embodiments described herein include a satellite cover panel for covering a satellite, particularly a payload bay of a satellite comprising an energy storage module, at least one energy generating module defining, at least partially, a first outer surface of the satellite cover panel, and a logic board defining, at least partially, a second outer surface of the satellite cover panel, wherein the first outer surface and the second outer surface face away from each other and from the energy storage module.Type: GrantFiled: July 23, 2018Date of Patent: August 24, 2021Assignee: Technische Universität MünchenInventors: Thomas Grübler, Martin Langer
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Publication number: 20210234618Abstract: Encoders and decoders for encoding and decoding data according to a coding scheme. The encoder converts N bits of input data into M voltage signals for transmission over M parallel wires to a decoder having one or two decoding stages that recover the N bits of data from the M voltage signals. The coding scheme is an N-bit, M-wire PAM-Q code in which each voltage signal wi has one of Q voltage levels I1-IQ, where I1<I2< . . . <IQ, and the different sets of M voltage signals for the different N-bit input values are permutations of a single set of M voltage signals. The decoder has a comparator stage. For the decoder having one other decoding stage, the other decoding stage is a computation stage or a logic stage that is before or after the comparator stage.Type: ApplicationFiled: January 24, 2020Publication date: July 29, 2021Applicants: Nokia Solutions and Networks Oy, Technische Universität MünchenInventors: Ariel Leonardo Vera Villarroel, Gerhard Kramer
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Patent number: 11045090Abstract: A medical imaging apparatus for combined X-ray and optical visualization is provided. It comprises: an X-ray detector positioned above a patient; an X-ray source positioned below a patient; a control device; and a camera setup adapted to deliver an optical stereoscopic or 3D image. Thereby, the camera setup is positioned adjacent to the X-ray detector above the patient, and the control device is adapted to calculate an optical 2D image or a 3D surface from the data delivered by the camera setup, that optical 2D image or 3D surface having a virtual viewpoint similar to the viewpoint of the X-ray source. It is further adapted to superimpose an X-ray image acquired by the X-ray detector and the optical 2D image or 3D surface in order to achieve an augmented optical/X-ray image.Type: GrantFiled: September 28, 2016Date of Patent: June 29, 2021Assignee: Technische Universität MünchenInventor: Nassir Navab
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Patent number: 11038525Abstract: A method (C) for converting a data signal (U), comprising (i) providing an input symbol stream (B) representative of the data signal (U), (ii) demultiplexing (DMX) the input symbol stream (B) to consecutively decompose the input symbol stream (B) into a number m of decomposed partial symbol streams (B_1, . . . , B_m), (iii) applying on each of the decomposed partial symbol streams (B_1, . . . , B_m) an assigned distribution matching process (DM_1, . . . , DM_m), thereby generating and outputting for each decomposed partial symbol stream (B_1, . . . , B_m) a respective pre-sequence (bn_1, . . . , bn_m) or n_j symbols as an intermediate output symbol sequence, and (iv) supplying the pre-sequences (bn_1, . . . , bn_m) to at least one symbol mapping process (BM) to generate and output a signal representative for a final output symbol sequence (S) as a converted data signal. Each of the distribution matching processes (DM_1, . . .Type: GrantFiled: September 29, 2017Date of Patent: June 15, 2021Assignee: Technische Universität MünchenInventors: Georg Böcherer, Patrick Schulte, Fabian Steiner
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Patent number: 10959088Abstract: A communication method (S) for communication between mobile units (10, 20), and in particular between vehicles, in which information transmitted between the mobile units (10, 20) is encoded on the transmitter side by means of an encoder (12-1, 22-1) and is decoded on the receiver side by means of a decoder (12-2, 22-2), and the mobile units (10, 20) are synchronized in communication (S3) with an external interface unit (30) outside the mobile units (10, 20) prior to communication (S5) with one another in that a codebook (Cj) defining or specifying an encoder (12-1, 22-1) and/or a decoder (12-2, 22-2) is determined (S2) by the external interface unit (30) and is communicated (S3) to the mobile units (10, 20).Type: GrantFiled: April 24, 2018Date of Patent: March 23, 2021Assignees: Technische Universität München, Bayerische Motoren Werke AktiengesellschaftInventors: Holger Boche, Christian Arendt