Abstract: The present invention relates to a method for compensation, for example, for temperature compensation of a fiber optic measurement system designed for determining a mechanical quantity. First and second fiber Bragg gratings have a respective Bragg wavelength, wherein the fiber Bragg gratings are irradiated with primary light. After applying a mechanical quantity to the first and second fiber Bragg gratings, the Bragg wavelengths of the fiber Bragg gratings are changed by the mechanical quantity.

Abstract: Device for contacting electrical energy storage cells of an energy store, which are each connected at their poles to a printed circuit board via an electrically and thermally conductive contact element, said printed circuit board being provided to separate an electrical current, received by the respective energy storage cell via the contact element, from a heat flow received via the contact element.

Abstract: The present invention relates to a method of producing a modified protein having an increased stability and/or improved folding efficiency as compared to the unmodified protein, the method comprising (i) modifying a nucleic acid molecule encoding a protein comprising at least one immunoglobulin constant domain-like region by (a-i) replacing the nucleotides encoding at least one amino acid, preferably an uncharged amino acid, in the loop separating the C strand from the D strand with nucleotides encoding a charged amino acid selected from the group consisting of Arg, Lys, His, Glu and Asp and/or replacing the nucleotides encoding at least one amino acid, preferably an uncharged amino acid, in the helix connecting the E strand with the F strand with nucleotides encoding a charged amino acid selected from the group consisting of Arg, Lys, His, Glu and Asp; (a-ii) replacing the nucleotides encoding at least one amino acid not having a side chain that can form a hydrogen bond in the loop separating the C strand fr

Abstract: The present invention is directed to a cross-reactive antibody, which specifically inhibits or blocks the mammalian Toll-like receptor 2 (TLR2)-mediated immune cell activation. The invention is further directed to an isolated nucleic acid or vector coding for the variable regions of the heavy and/or light chain of the antibody. It is further providing a pharmaceutical composition comprising the antibody, nucleic acid or vector and is directed to the use of the composition in the prevention and/or treatment of inflammatory processes or any other process induced by bacterial infection, trauma, or chronic inflammation, or for the prevention and/or treatment of bacteriaemia or sepsis.

Abstract: Shown is a ski binding for fastening a ski boot with a firm or flexible sole onto a ski, which encompasses the following: a forefoot-fixing module with a fastening section and movable section and a support for the heel of the ski boot, wherein the movable section of the forefoot-fixing module encompasses a front receptacle and a rear receptacle, wherein the front and rear receptacle are together suitable for fastening a front section of the ski boot in the forefoot-fixing module, and releasing the latter given a correspondingly high torque. The ski binding has a Telemark downhill mode and/or a climbing mode and/or an alpine downhill mode.

Abstract: The invention relates to a method for presetting a vehicle seat (1) for a passenger (2) using the vehicle seat. Said vehicle seat comprises at least parts of a presetting device (12). The invention is characterized in that in a first step, information about the passenger is transmitted to the presetting device transmits and in a second step, the vehicle seat (1) is modified by said presetting device (12) such that the vehicle seat (1) adopts as the presetting for the passenger (2), a first vehicle seat configuration based on the transmitted information.

Abstract: A system and method for the evaluation of hearing implant signal processing is described. A cochlear implant signal processor converts a speech signal input into multi-channel stimulation pulse sequences for a cochlear implant electrode array. A temporal feature processing module extracts temporal feature information from the stimulation pulse sequences. A speech recognition engine evaluates the temporal information using automatic speech recognition to produce speech recognition outputs corresponding to the speech signal input.

Abstract: A method for the adjustment of an optical measurement system comprises providing an optical measurement system, which comprises, as optical elements, a beam splitter; a first photo sensor, exposed by a first partial beam from the beam splitter; an optical filter; a second photo sensor, arranged downstream of the optical filter, exposed by a second partial beam from the beam splitter. Additionally, the angularity and relative position between multiple optical elements is designed to be adjustable.

Abstract: A method and system for prediction of respiratory motion from 3D thoracic images is disclosed. A patient-specific anatomical model of the respiratory system is generated from 3D thoracic images of a patient. The patient-specific anatomical model of the respiratory system is deformed using a biomechanical model. The biomechanical model is personalized for the patient by estimating a patient-specific thoracic pressure force field to drive the biomechanical model. Respiratory motion of the patient is predicted using the personalized biomechanical model driven by the patient-specific thoracic pressure force field.

Abstract: An approach is described for evaluating a selected hearing stimulation strategy in a hearing impaired patient. A healthy neurogram represents a normal auditory neural response to a selected sound input by a healthy auditory system. An impaired neurogram represents an impaired auditory neural response to the selected sound input by a hearing impaired patient auditory system using the hearing stimulation strategy. The impaired neurogram is compared to the healthy neurogram based on: i. partitioning the neurograms into corresponding temporal and frequency domain tiles, ii. determining local variability between corresponding individual tiles by comparison of selected tile features, iii. determining global variability between the neurograms by weighted averaging of the individual tile comparisons, and iv. developing from the local and global variabilities a perception estimate representing effectiveness of the selected hearing stimulation strategy in approaching normal healthy hearing for the implanted patient.

Abstract: A copolymer that has sufficient dispersibility to various kinds of cements, including those having low fluidity (difficult cement). The copolymer is obtained by polymerizing monomer components including an unsaturated (poly)alkylene glycol ether monomer (a), an unsaturated carboxylic acid monomer (b), and an unsaturated cross-linkable monomer (c) or an unsaturated cross-linkable monomer (d). The unsaturated cross-linkable monomer (c) is allyl itaconate or allyl citraconate, or ester thereof. The unsaturated cross-linkable monomer (d) is an ester obtained by reaction of at least one acid, selected from the group consisting of (meth)acrylic acid, maleic acid, fumaric acid, itaconic acid, and citraconic acid and ester derived from the acids, with a (poly)alkylene glycol or a (poly)alkylene glycol ether.

Abstract: A device adapted for generating a rotatory ultrasonic vibration on a tool that includes a first part which is adapted for the rotationally fixed connection of the device to a spindle of a machine tool that rotates about an axis of rotation, and a second part which is adapted for the rotationally fixed connection of the device to a tool. The device also includes a claw coupling which is configured to connect the first and second parts for rotation with one another and has a form fit of at least one first flank on the first part and at least one second flank, lying opposite the first flank, on the second part. The device also includes at least one piezoelectric oscillation element arranged between first and second flanks of the claw coupling configured for generating a rotatory ultrasonic vibration about the axis of rotation.

Abstract: A method for state monitoring of a rotor blade of a wind turbine is described. The method comprises: measuring an acceleration of the rotor blade with a first signal, wherein the acceleration is measured at a first position at a predetermined distance from the rotor blade root in at least one direction comprising a first directional component orthogonal to the axis of the rotor blade, measuring a strain of the rotor blade with a second signal, wherein the strain is measured at a second position disposed in the area of the first position to the rotor blade root, determining a first positional change at the first position on the basis of the acceleration, determining a first value corresponding to the rotor blade stiffness or to the rotor blade elasticity by means of calculation on the basis of the first positional change and the strain, and determining the rotor blade state from the first value.

Abstract: The present invention provides a method for installing at least one sensor device within a rotor blade of a wind turbine. A first substantially planar light beam is emitted in the interior of the rotor blade. Finally, at least one second substantially planar light beam is emitted in the interior of the rotor blade, wherein the plane of the first planar light beam is oriented at a predetermined angle to the plane of the second planar light beam. Further, the planes of the first and second planar light beams are aligned on the blade flange of the rotor blade. At least one sensor device is subsequently aligned in reference to the planar light beams.

Abstract: Increased in vivo and/or in vitro stability is imparted to a biologically active protein by fusing to an amino acid sequence consisting of at least about 100 amino acid residues, which consist essentially of Alanine, Serine and Proline, which form a random coil conformation. Specific examples are described. Also described are related nucleic acids, vectors and cells encoding such amino acids; compositions of biologically active proteins fused to a random coil domain, and methods of making and using the compounds and compositions of the invention.

Abstract: We discovered that a biosynthetic polypeptide, consisting of at least about 50 proline (Pro) and alanine (Ala) amino acid residues, forms a random coil, and increases the stability of other compounds to which it is conjugated, such as small molecules and polypeptides. We describe such biosynthetic polypeptides, constructs containing such polypeptides, ways of making them, and their use.

Abstract: A shaft power plant for energy conversion of a discharge between a headwater and a tailwater, comprising a vertical shaft, the top of which forms an inflow plane which is parallel to the bed and extends below the headwater water level, wherein the shaft is open toward the top and is closed by a base at its bottom end, a unit composed of a turbine and an electrical machine, wherein the unit is arranged entirely under water in the shaft and wherein the turbine is arranged for water to pass through vertically, and an outflow, which is connected to the turbine, represents a closed flow channel and leads through a through-passage in the shaft to the tailwater, wherein, in a horizontal plane of a turbine runner of the turbine, a first cross-sectional area of the shaft is much larger than a second cross-sectional area taken up by the turbine runner.

Abstract: The invention relates to a friction stir welding apparatus for joining workpieces 1, 2, having a welding pin 3, which is rotatable about its center axis 9 by means of a drive, and having at least one clamping apparatus for clamping the workpieces 1, 2 to be joined, characterized in that the clamping apparatus comprises at least two clamping elements 10, 11, which respectively have an undercut guideway 12, the guideways 12 being arranged parallel to one another and parallel to a joining region 8, in that between the clamping elements 10, 11 is arranged a sliding element 13, which is secured by the guideways 12 against the workpieces 1, 2 and is translatorily displaceable along the guideways 12, and in that the sliding element 12 is provided with an opening 14 for the lead-through of the welding pin 3, and further relates to a method for friction stir welding, using the above-stated apparatus.

Abstract: An industrial truck is shown with a lifting frame, on which a load-receiving section is arranged so as to be movable vertically. The load-receiving section has at least one degree of movement freedom with respect to the lifting frame, which lies in a plane perpendicular to the main direction of travel of the industrial truck and has at least one horizontal component. In addition, a vibration control system is provided for damping or preventing vibrations in the relative position of load-receiving section and lifting frame.

Abstract: The invention relates to a nucleic acid construct comprising an adenoviral E2 late promoter or a fragment thereof and a nucleic acid. The nucleic acid is selected from the group of transgenes, genes and nucleic acids which are respectively different from adenoviral nucleic acid controlled by an E2 late promoter. The invention also relates to the uses of said nucleic acid construct.