Abstract: An optical sensor for detecting chemical, biochemical or biological substances includes a laser and a semiconductor chip. The sensor includes at least one photodetector and at least one high-contrast grating that are monolithically integrated in the semiconductor chip. The high-contrast grating is configured to optically couple radiation emitted by the laser into the photodetector. The coupling behavior of the high-contrast grating depends on the optical properties of external substances that are brought near to or in contact with the high-contrast grating.

Abstract: A method and apparatus for modeling smoke turbulence is disclosed. The method of modeling smoke turbulence includes detecting a turbulent area comprising smoke turbulence in a low-resolution image, and searching for a high-resolution patch matching the turbulent area in a memory that comprises high-resolution patches representing smoke turbulence extracted from high-resolution images. The method also models the smoke turbulence by synthesizing the retrieved patch to the low-resolution image.

Abstract: A device for electromechanically assisted roller burnishing (EMRB) may comprise: a roller burnishing tool with exactly one current-leading roller burnishing element for burnishing a workpiece, wherein the roller burnishing element represents a first electrical contact element for electrically contacting first location of the workpiece, and a second electrical contact element for electrically contacting second location of the workpiece; wherein the first and the second electrical contact elements can be positioned at a settable spatial distance to one another, so that on moving the roller burnishing element on the workpiece, a current path in the workpiece between the first and the second contact elements is always a constant length.

Abstract: The invention relates to a method for production of single-stranded macronucleotides by amplifying and ligating an extended monomeric single-stranded target nucleic acid sequence (targetss) into a repetitive cluster of double-stranded target nucleic acid sequences (targetds), and subsequently cloning the construct into a vector (aptagene vector). The aptagene vector is transformed into host cells for replication of the aptagene and isolated in order to optain single-stranded target sequences (targetss). The invention also relates to single-stranded nucleic acids, produced by a method of the invention.

Abstract: The present invention relates to a method and a device for an error correction of transmitted data. For this purpose, the transmitted data are encoded in a block code, wherein the block code comprises a number of data bits and an additional number of redundant bits. Herein the block code is described by a parity-check matrix H, wherein columns of the parity-check matrix Hare inherently related to the data bits of the block code.

Abstract: The present invention relates to hydroxyindalpine derivatives of formula (I) as defined herein and pharmaceutical compositions comprising these compounds, as well as their medical use, particularly in the treatment or prevention of gastrointestinal diseases/disorders, such as constipation and functional dyspepsia.

Abstract: The invention relates to a method for producing an organic component in which a layer stack comprising an electrode, a counter-electrode and one or more organic layers is produced and in which a functional layer with metal particle nanoclusters is formed in the layer stack, wherein here in the layer stack a base layer of an inorganic material is produced on an underlying stack region which comprises at least one organic layer and an arrangement of isolated metal particle nanoclusters is formed on the base layer. The invention further relates to an organic component.

Abstract: The invention relates to a method for the construction of a shaped body from photopolymerizable material by using lithography-based generative production (rapid prototyping), in which a layer of liquid photopolymerizable material is defined on a production platform (1, 2, 3, 4), the layer is polymerized in an exposure region having a predetermined contour by exposure, a further layer of photopolymerizable material is defined on the polymerized layer, the layer defined last is polymerized by exposure in an exposure region having a predetermined contour for the layer defined last, and the latter two steps are repeated until a shaped body having a predetermined shape has been formed by the sequence of cured layers with contours predetermined layer by layer, wherein ink is applied onto at least one layer inside the predetermined contour, wherein the production platform is suspended moveably and wherein the production platform is brought, after the polymerization of a layer in a processing station for polymerizing

Abstract: A shaft power plant for generating electricity by energy conversion of an outflow between upper water and lower water in a river includes at least two power plant modules, each having a vertical shaft with an open top and a shaft crown forming an inflow plane. The inflow plane is substantially parallel with the river bed and extends below a water level of the upper water. Each of the power plant modules also has a turbine generator unit arranged in the shaft. The power plant also includes an ecological connecting channel formed as an outflow from the upper water into the lower water without generating electricity by energy conversion.

Abstract: The present invention provides a method and apparatus for depth image acquisition of an object wherein at least two time-of-flight cameras are provided and the object is illuminated with a plurality of different light emission states by emitting light signals from each camera. Measurements of the light reflected by the object during each light emission state are obtained at all the cameras wherein the measurements may then be used to optimize the depth images at each of the cameras.

Abstract: The invention relates to a method for producing activated carbon provided and/or impregnated with a metal-organic framework substance (MOF material), the activated carbon being in particular in the form of discrete activated carbon particles, and preferably for producing an activated carbon with a reactive and/or catalytic action. The metal-organic framework substance is produced in situ in the pores and/or in the pore system of the activated carbon, starting from at least one metal precursor compound (MP) containing a metal and at least one ligand precursor (LP).

Abstract: The present invention relates to a method for compensation, for example, for temperature compensation of a fiber optic measurement system designed for determining a mechanical quantity. First and second fiber Bragg gratings have a respective Bragg wavelength, wherein the fiber Bragg gratings are irradiated with primary light. After applying a mechanical quantity to the first and second fiber Bragg gratings, the Bragg wavelengths of the fiber Bragg gratings are changed by the mechanical quantity.

Abstract: Method for the automatic analysis of an image of a biological sample with respect to a pathological relevance, wherein a)local features of the image are aggregated to a global feature of the image using a bag of visual word approach, b) step a) is repeated at least two times using different methods resulting in at least two bag of word feature datasets, c) computation of at least two similarity measures using the bag of word features obtained from a training image dataset and bag of word features from the image, d) the image training dataset comprising a set of visual words, classifier parameters, including kernel weights and bag of word features from the training images, e) the computation of the at least two similarity measures is subject to an adaptive computation of kernel normalization parameters and/or kernel width parameters, f) for each image one score is computed depending on the classifier parameters and kernel weights and the at least two similarity measures, the at least one score being a measure

Abstract: Device for contacting electrical energy storage cells of an energy store, which are each connected at their poles to a printed circuit board via an electrically and thermally conductive contact element, said printed circuit board being provided to separate an electrical current, received by the respective energy storage cell via the contact element, from a heat flow received via the contact element.

Abstract: An embodiment of the invention relates to a method for generating short optical pulses comprising the steps of: operating a single section semiconductor laser in a nonlinear regime to emit chirped optical pulses at an output facet of the laser cavity, and compressing the chirped optical pulses outside the laser cavity using a dispersive element in order to generate the short optical pulses.

Abstract: An embodiment of the present invention relates to a radiation emitting device comprising: a radiation emitter for generating radiation; a waveguide; a lens placed between the radiation emitter and the waveguide and directing a first portion of the radiation towards the waveguide; a sleeve that comprises a reflective inner surface and is placed between the radiation emitter and the waveguide, said inner reflective surface coupling a second portion of the radiation into the waveguide; wherein the lens and the sleeve are separate components that can be positioned relative to each other during fabrication of the radiation emitting device.

Abstract: In a method for producing a substrate for soil improvement with water-storing property on the basis of lignin, lignin is provided and oxidized alternatively in an aqueous alkaline or a pH-neutral aqueous suspension, wherein the pH-neutral aqueous suspension after oxidation of the lignin is converted into an alkaline medium. The lignin is cross-linked in an aqueous alkaline medium by multi-functional compounds. Subsequently, the lignin is neutralized, dried, and comminuted. The produced lignin is used as a substrate for improvement of soil properties in that the substrate is used as a water storage that, compared to water storages of non-modified technical lignins, exhibits a significantly higher water adsorption capacity or swelling capacity.

Abstract: The present invention relates to a method of producing a modified protein having an increased stability and/or improved folding efficiency as compared to the unmodified protein, the method comprising (i) modifying a nucleic acid molecule encoding a protein comprising at least one immunoglobulin constant domain-like region by (a-i) replacing the nucleotides encoding at least one amino acid, preferably an uncharged amino acid, in the loop separating the C strand from the D strand with nucleotides encoding a charged amino acid selected from the group consisting of Arg, Lys, His, Glu and Asp and/or replacing the nucleotides encoding at least one amino acid, preferably an uncharged amino acid, in the helix connecting the E strand with the F strand with nucleotides encoding a charged amino acid selected from the group consisting of Arg, Lys, His, Glu and Asp; (a-ii) replacing the nucleotides encoding at least one amino acid not having a side chain that can form a hydrogen bond in the loop separating the C strand fr

Abstract: The invention relates to a composition which contains at least one anti-slan antibody and to its diagnostic and therapeutic use. The composition according to the invention comprises: a) at least one anti-slan antibody, b) at least one binding unit which binds to a co-stimulus binding to a co-stimulus-specific receptor on dendritic cells, thereby bringing about the modulation, preferably the activation, of said dendritic cells, and c) at least one antigen. The invention furthermore comprises anti-slan antibodies which include CDRs with the following sequences: variable region of the heavy chain: CDR1 (SEQ ID No. 1), CDR2 (SEQ ID No. 2), where Xaa is selected from among M, L, F, or I, preferably from among M or I, CDR3 (SEQ ID No. 5) and variable region of the light chain: CDR1 (SEQ ID No. 6), where Xaa is selected from among S, T, N, Q, H, K or R, preferably from among S or N, CDR2 (SEQ ID No. 9) and CDR3 (SEQ ID No. 10).

Abstract: The invention relates to a method for the separation of a polarizable bioparticle comprising the steps: a) dielectrophoretic preseparation of a polarizable bioparticle from a suspension of bioparticles; b) fluidic separation of the selected bioparticle by fixing the bioparticle in a dielectrophoretic field cage and circulating fluid around the bioparticle; c) transferring the separated bioparticle from the dielectrophoretic field cage to a culture chamber; d) dielectrophoretic fixing of the separated bioparticle in the culture chamber and study, observation, manipulation and/or culturing of the separated bioparticle. The invention further relates to a microfluidic system and use thereof.