Abstract: A classifying device for classifying cells in real-time, comprising: as alignment unit configured to align a cell to be classified along the cell's major axis; and a classifying unit configured to classify the aligned cell using a multilayer perceptron, MLP; wherein the MLP classifies the aligned cell based on one or more images of the aligned cell. By executing the classifying device, an improved and efficient cell classification in real-time based on cell images can be provided, while labelling of the cells to be classified can be avoided.

Abstract: A dual-mode microwave applicator for treating tissue comprises a control unit, a rod-shaped element, a coaxial line, and a metal sleeve. The control unit controls the applicator in an application mode and a sensing mode. In the application mode microwave radiation is applied and during the sensing mode tumorous tissue is detected. The rod-shaped element comprises a tip. The coaxial line is formed in the rod-shaped element to relay microwaves to the tip for treatment of the tissue. The coaxial line comprises an inner conductor and an outer conductor. The outer conductor includes a slot of a slot length formed at a slot distance from the tip. The metal sleeve at a sleeve distance from the slot. The sleeve distance is about 0.55 mm, the slot length is about 1.75 mm, and the slot distance is about 7.7 mm.

Abstract: A method for recycling powdered paint waste is provided in which, the powdered paint waste is being treated with the aid of a reactant in such a way that its adhesion to surfaces and especially to metal surfaces is reduced or eliminated. The treatment of the powdered paint waste allows the powdered paint waste to be additionally processed under the influence of heat and to use it as a starting material in various recycling processes or in other processes.

Abstract: In a method for setting up a pipeline section of a pipe system in a heat network, which is provided for transferring a heat transfer fluid between a heat provider and a heat consumer, the pipeline section is subdivided into segments in a segmentation step. A segment characteristic variable is determined for each segment based on a physical soil characteristic variable. The determined segment characteristic variables of two adjacent segments differ by more than a predefined segment characteristic variable difference value. In a bedding determination step, segment embedding of a pipeline segment, introduced in the trench in this segment, in a water-permeable segment bedding material is predefined for each segment such that a heat loss of the heat transfer fluid transferred in the pipeline segment, which is averaged over the segment and is based on a unit of length, is lower than a predefined heat loss limit value.

Abstract: The present invention relates to polymeric particles comprising a biodegradable polymer, and at least one microorganism in a total concentration of at least 108 CFU/g dry weight that is stable for at least 35 weeks at 30° C. and optionally additional carriers and additives as well as to methods for producing polymeric particles and use thereof.

Abstract: The invention relates to a method for actively balancing a rotor (1), comprising: providing a device with a rotor (1) that can be rotated around an axis of rotation and a mechanism (2) allocated to the rotor (1) for actively balancing, in which a magnetic fluid (7) is received in a fluid chamber (6) formed on the rotor (1), which partially fills the fluid chamber (6) and contains at least one of the following fluids: ferrofluid and magnetorheological fluid; holding the magnetic fluid (7) by means of a permanent magnetic field of a permanent magnet (5) arranged on the rotor (1) in an initial position in the fluid chamber (6); rotating the rotor (1) around the axis of rotation (3), and passing the fluid chamber (6) and permanent magnet (5) by an electrical exciter system with a fixedly arranged electromagnet (8) during the rotation of the rotor (1), wherein the permanent magnetic field of the permanent magnet (5) and an electromagnetic field of the electromagnet (8) here overlap in an activated state for active

Abstract: The present invention relates to the field of immunology, molecular biology and therapeutics. In particular, the invention relates to novel artificial feeder cells for activation and expansion of natural killer (NK) cells. The artificial feeder cell expresses endogenous ligands (HLA C1, C2, 5 and Bw4 type) for killer cell immunoglobulin-like receptors (KIRs), non-KIR binding Bw6 ligand, endogenous HLA-E-ligand for inhibitory NKG2A receptor, and comprises at least one stimulatory cytokine either membrane bound or secreted or at least one co-stimulatory ligand where those ligands and cytokines each specifically bind to a cognate receptor on a NK cell of interest, thereby mediating expansion of the NK cell. The invention can be used as an “off the 10 shelf” artificial feeder cell that can be readily designed to expand a NK cell or a NK subset of interest and also specifically expand NK cells modified with a chimeric antigen receptor (CAR).

Abstract: The present invention discloses a method for assessing the capacity of a substance to treat or prevent hepadnavirus infection. A reporter virus carrying genetic information for a first fragment of a recombinase and a reporter cell expressing a second fragment of the recombinase are used. When the reporter virus infects the reporter cell, the two fragments of the recombinase associate and excise a stop cassette that is flanked by two recombination sites and blocks the expression of a reporter gene. Accordingly, the present invention relates to a method of assessing the capacity of a substance to treat or prevent hepadnavirus infection, a hepadnavirus comprising a nucleic acid encoding a first fragment of a recombinase and a mammalian hepatocyte or hepatoma cell comprising a nucleic acid encoding a second fragment of a recombinase and a nucleic acid comprising a stop cassette flanked by two recombination sites fused to a reporter gene.

Abstract: The invention relates to a method for operating a sorption system (1), the sorption system comprising the following: a cooling fluid circuit (8), which has a cooling fluid; a process medium circuit (6), which has a refrigerant and a solvent; an absorber (3), which is connected to the cooling fluid circuit (8) and to the process medium circuit (6); a condenser (5), which is connected to the cooling fluid circuit (8) and to the process medium circuit (6); and a control device. During operation of the sorption system (1), the cooling fluid is fed to the absorber (3) and to the condenser (5), and a feed of the cooling fluid to the absorber (3) and a feed of the cooling fluid to the condenser (5) are controlled differently from each other by means of the control device. The invention further relates to an arrangement for a sorption system (1) and to a sorpotion system (1).

Abstract: A method for improving a biogas production is provided in which an organic substrate is pretreated by various methods. In particular, the method includes a combination of a magnetic and an enzymatic pretreatment of the substrate with an attractive specific energy gain.

Abstract: By accurately predicting industrial aging processes (IAP), such as the slow deactivation of a catalyst in a chemical plant, it is possible to schedule maintenance events further in advance, thereby ensuring a cost-efficient and reliable operation of the plant. So far, these degradation processes were usually described by mechanistic models or simple empirical prediction models. In order to accurately predict IAP, data-driven models are proposed, comparing some traditional stateless models (linear and kernel ridge regression, as well as feed-forward neural networks) to more complex stateful recurrent neural networks (echo state networks and long short-term memory networks). Additionally, variations of the stateful models are discussed. In particular, stateful models using mechanistical pre-knowledge about the degradation dynamics (hybrid models).

Abstract: The present invention relates to specific complexes comprising heavy metal ions having an atomic number of 23 or higher and 83 or lower (in particular Ag1+, Ba2+, Pb2+, Gd3+ and Bi3+) and one or more hematein ligand(s). In particular, the invention relates to the use of the complexes as ex vivo contrast agents for a computed tomography scanning of a biological sample. Moreover, the invention relates to specific ex vivo methods for investigating a biological sample by means of computed tomography scanning methods, wherein the method comprises staining the biological sample with a solution comprising one or more of the complex(es); or wherein the method comprises staining the biological sample with a staining solution comprising hematein, and separately contacting the biological sample with one or more staining solution(s) comprising one or more heavy metal ions having an atomic number of 23 or higher and 83 or lower (in particular Ag1+, Ba2+, Pb2+, Gd3+ and Bi3+).

Abstract: A method of operating a storage means, wherein for writing and storing a storage item to the storage means the storage item to be written and stored—in particular by using the concept and theory of identification—is provided, a encoding process by means of randomization is applied to the storage item to generate and to provide a randomized encoded storage item, and the randomized encoded storage item is written and stored to the storage means. At least a first randomization process is underlying the encoding process and is a randomization process dedicated and assigned to the underlying storage means. The present disclosure further refers to a unit for operating a storage means, to a storage means and to a system for processing data. By having two randomization processes underlying the encoding process, a distinction can be made between a secrecy insuring and secrecy non-ensuring randomization processes.

Abstract: The invention relates to a method for operating a memory assembly. A physical address is received. The physical address is associated with a first memory segment of a memory assembly. The physical address is modified to a modified physical address. The modified physical address is associated with a second memory segment of the memory assembly.

Abstract: The present invention relates to a method for producing a substrate (2) which is coated with an alkali metal (1), in which method a promoter layer (3) which is composed of a material which reacts with the alkali metal (1) by at least partial chemical reduction of the promoter layer (3) is applied to a surface of the substrate (2) and a surface of the promoter layer (3) is acted on by an alkali metal (1) and then the alkali metal (1) is converted into the solid phase and a coating containing the alkali metal is formed.

Abstract: To determine the sex of a bird egg, a hole is produced at the blunt end of the bird egg, wherein the hole affects the calcareous shell and the outer shell membrane, whereas the inner shell membrane remains intact. In the region of the hole at the blunt end, beneath the intact inner shell membrane, at least one blood vessel is registered and the blood therein is excited by means of a preset incident radiation, the back-scattered radiation of which blood is measured, detected and evaluated for the sex determination.

Abstract: A particulate matter sensor system for sensing particulate matter in a fluid includes a substrate and a cover disposed on the substrate. The cover defines at least a portion of a flow path through the microfluidic system. The sensor system includes a particulate matter sensor disposed in an interior space between the cover and the substrate. The particulate matter sensor includes an integrated sensor device electrically connected to the substrate. The flow path is defined through the particulate matter sensor. The sensor system includes a fluid circulation device disposed in the interior space between the cover and the substrate and configured to cause fluid to flow along the flow path through the microfluidic system.

Abstract: The present invention relates to a sigma-delta analogue-to-digital converter. The sigma-delta analogue-to-digital converter comprises a transconductance stage having first, second and third terminals. A capacitor is connected in parallel at the third terminal. Further, the sigma-delta analogue-to-digital converter comprises a quantiser at the third terminal of the transconductance stage with feedback by a voltage digital-to-analogue converter for feeding back a feedback signal to one of the terminals of the transconductance stage.

Abstract: A device for control and closed-loop control of an actuating system of an aircraft is disclosed. The device has a first input interface, which is configured to receive first input data indicating a reference variable, a second input interface, which is configured to receive second input data indicating a controlled variable, and a control output, which is configured to output a control signal. The control signal indicates a manipulated variable for an actuating system of an aircraft, which is to be controlled by means of the actuating system. The reference variable indicates a target acceleration at a point of the aircraft that is to be controlled by means of the actuating system, and the controlled variable indicates an actual acceleration of the aircraft at the point.

Abstract: Use of Keplerate type polyoxomolybdates of the general structure Mo72M30, wherein M is selected from the group consisting of Fe, Cr, V or Mo2, for decontaminating aqueous media (water) from inorganic and organic pollutants.