Patents Assigned to The Board of Supervisors of Louisiana State University
  • Rice cultivar designated ‘CL272’
    Patent number: 11006600
    Abstract: The herbicide-tolerant rice cultivar designated ‘CL272’ and its hybrids and derivatives are disclosed. CL272 is a novel, herbicide-resistant, early maturing, semidwarf, medium-grain rice cultivar with improved yield and improved disease resistance. This invention also pertains to methods for producing a hybrid or new variety by crossing the rice variety ‘CL272’ with another rice line, one or more times. This invention allows for single-gene converted plants of ‘CL272.’ This invention also provides regenerable cells for use in tissue culture of rice plant ‘CL272.’ The present invention provides a method for treating rice.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: May 18, 2021
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: Steven D. Linscombe
  • Compositions and methods for ameliorating pain and reducing fever
    Patent number: 11007199
    Abstract: This invention is directed to compositions, methods and kits that can be used for the treatment or amelioration of pain and fever.
    Type: Grant
    Filed: January 9, 2020
    Date of Patent: May 18, 2021
    Assignees: The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, University of Alcala De Hernares, South Rampart Pharma, LLC
    Inventors: Nicolas Bazan, Hernan Bazan, Julio Alvarez-Builla Gomez, Dennis Paul, Carolina Burgos Garcia
  • Methods of detecting, diagnosing, and treating carotid plaque vulnerability
    Patent number: 11009514
    Abstract: Disclosed are methods of, and assay and kits for, detecting and diagnosing methods of detecting, diagnosing, vulnerable carotid artery disease capable of becoming acutely symptomatic using the levels of Resolvin D1 (RvD1), docosahexaenoic acid (DHA), and arachidonic acid (AA). Also disclosed are methods of treating carotid artery disease and methods of identifying agents for use in the treatment of carotid artery disease.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: May 18, 2021
    Assignees: OCHSNER HEALTH SYSTEM, THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURE AND MECHANICAL COLLEGE, THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND
    Inventors: Hernan A. Bazan, Yan Lu, Song Hong, Zhide Fang, Bokkyoo Jun, Thomas C. Woods
  • Rice cultivar designated ‘CL153’
    Patent number: 11006595
    Abstract: The herbicide-tolerant rice cultivar designated ‘CL153’ and its hybrids and derivatives are disclosed. CL153 is a novel, herbicide-resistant, high yielding, early maturing, semidwarf, long-grain rice cultivar with excellent grain yield, good grain quality, and produces plans with very good resistance to blast disease. This invention also pertains to methods for producing a hybrid or new variety by crossing the rice variety ‘CL153’ with another rice line, one or more times. This invention allows for single-gene converted plants of ‘CL153.’ This invention also provides regenerable cells for use in tissue culture of rice plant ‘CL153.’ The present invention provides a method for controlling weeds in the vicinity of rice.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: May 18, 2021
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: Steven D. Linscombe
  • HIGH PERFORMANCE AND RECYCLABLE THERMOSET INK FOR 3D OR 4D PRINTING
    Publication number: 20210122865
    Abstract: A UV-curable and recyclable thermoset shape memory polymer is provided. The polymer includes a vitrimer-based monomer and a photoinitiator. The vitrimer-based monomer includes a first unit rendering a high chain stiffness upon polymerization of the monomer, and a second photopolymerizable unit for photopolymerization of the monomer under a UV irradiation. The polymer has high strength, high stiffness, high recovery stress, high energy storage, reasonable recycling efficiency, and is printable using SLA with high resolution.
    Type: Application
    Filed: April 30, 2019
    Publication date: April 29, 2021
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Ang LI, Guoqiang LI
  • Green alga bicarbonate transporter and uses thereof
    Patent number: 10982226
    Abstract: Provided herein are green alga Cia8 polypeptides and the polynucleotides that encode them. Also provided herein are transformed cells and transgenic plants that include one or more of the polynucleotides and/or polypeptides provided herein.
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: April 20, 2021
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: James V. Moroney, Marylou C. Machingura, Joanna N. Bajsa-Hirschel
  • Isothiocyanatostilbenes as a novel method and product for treating cancer
    Patent number: 10980765
    Abstract: Products and methods for treating cancer in a human patient comprising administering to the patient therapeutically effective amount of a first pharmaceutically active agent, wherein the first pharmaceutically active agent is one of an isothiocyanatostilbene and a pharmacologically acceptable salt, solvate, ester, amide, clathrate, stereoisomer, enantiomer, prodrug or analog thereof, or a combination thereof.
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: April 20, 2021
    Assignees: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY, BOARD OF SUPERVISORS FOR THE UNIVERSITY OF LOUISIA
    Inventors: Alana Lea Gray, James Cardelli, David Thomas Coleman, Khalid El-Sayed, Mohamed M. Mohyeldin
  • Palatable Foods for a Methionine-Restricted Diet
    Publication number: 20210100268
    Abstract: A method is disclosed for making palatable methionine-restricted foods, to deliver a methionine-restricted diet to human or veterinary patients. A protein or a food product containing protein is partially oxidized, preferably with ozone, to oxidize nearly all of the methionine and cysteine. After oxidation, tryptophan and lysine are optionally added back since they tend to be oxidized also. Optionally, a small amount of methionine is also added back so that the final methionine is within a preferred range of about 0.85 to about 1.8 gram methionine per 100 gram total protein, preferably about 1.2 gram per 100 gram total protein.
    Type: Application
    Filed: December 16, 2020
    Publication date: April 8, 2021
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: John W. Finley, Thomas Gettys, Frank L. Greenway
  • Method for harvesting stem and progenitor cells and method of treatment of kidney disease and neurological disease
    Patent number: 10968433
    Abstract: A method of generating one of podocyte progenitor cells and neural stem/progenitor cells comprising the steps of collecting a urine specimen from a patient; centrifuging the urine specimen; and removing the one of podocyte progenitor cells and neural stem/progenitor cells.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: April 6, 2021
    Assignee: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY
    Inventor: Yuping Wang
  • Compositions and methods for detecting proteinopathies
    Patent number: 10962553
    Abstract: This invention is directed to compositions and methods for detecting proteinopathies.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: March 30, 2021
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: Shyamal D. Desai
  • Methods for treating c-Met-dependent cancers
    Patent number: 10959968
    Abstract: A method of treating cancer or a precancer condition in a mammal comprising administering a therapeutically effective amount of a homovanillyl sinapate analog or pharmacologically acceptable salt, solvate, ester, amide, clathrate, stereoisomer, enantiomer, prodrug or analog thereof, or a combination thereof.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: March 30, 2021
    Assignee: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY
    Inventors: James Allen Cardelli, Ana-Maria Dragoi, Khalid El-Sayed, Mohamed M. Mohyeldin
  • Load dissipating arthoplasty prostheses
    Patent number: 10959852
    Abstract: A load dissipating arthroplasty prosthesis comprising a shell, an articular device extending into the shell through a collar defined in the sell, a head and neck portion of the articular device extending from the collar, a shaft portion of the articular device extending into the shell, and a plurality of shock absorbing arcuate linkers spacing and allowing limited movement between the shell and the articular device.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: March 30, 2021
    Assignee: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY
    Inventors: Gulshan Neville Sunavala-Dossabhoy, Kevin McCarthy
  • Delivery of bioactive, nanoencapsulated antioxidants
    Patent number: 10952974
    Abstract: Methods and compositions are disclosed for delivering lutein or other antioxidant to target tissues such as the eye, in bioactive form, while protecting the antioxidant from degradation. The antioxidant is encapsulated in nanoparticles comprising a protein such as zein or a polymer such as poly(lactic-co-glycolic acid) (PLGA). Preferably a surfactant is associated with the nanoparticles as well, further helping to protect the antioxidant. After the nanoparticles are administered to the target tissue, bioactive antioxidant is released to the tissue over time. Optionally, the nanoparticles are admixed with a thermosensitive, bioadhesive gel to promote slow release of antioxidant. The methods and compositions are useful for treating or preventing conditions such as age-related macular degeneration or cataracts.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: March 23, 2021
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Cristina M. Sabliov, Carlos E. Astete, Ede Bodoki, Oliviu Vostinaru, Ovidiu Ciprian Samoil{hacek over (a)}, Elena Dinte
  • Methods for temporary fracture isolation
    Patent number: 10954767
    Abstract: Methods for temporary fracture isolation are provided. An existing fracture is treated with a chemical diverter. The chemical diverter is exposed to conditions causing it to expand, plugging the fracture. A new fracture can be created through the application of pressure and fluid, without disrupting the plugged fracture. The chemical diverter can then be removed through biodegradation or the application of a solvent to reopen the first fracture.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: March 23, 2021
    Assignee: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY
    Inventors: Arash Dahi Taleghani, Guoqiang Li
  • Smart rutting and cracking resistant asphalt pavement incorporating shape memory polymers
    Patent number: 10954390
    Abstract: The low temperature cracking and high temperature rutting of polymer-modified asphalt concrete pavement can be reduced. The composite includes asphalt and at least one polymer that expands at low temperature, triggered by cooling-induced tensile stress, to reduce thermal cracking. The composite includes at least one polymer that expands at high temperature, so that the composite recovers after compression induced by traffic loading at higher temperatures, thereby reducing rutting. The system reduces thermal stress, and reduces or even eliminates thermal cracking and rutting. Shape memory polymers (SMPs) are used to improve asphalt compositions so that they better resist both thermal cracking and rutting. The SMP(s) can be incorporated into the asphalt, or a portion of fine aggregates can be replaced with SMP particles or SMP fibers, or aggregate replacement and asphalt modification can be combined.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: March 23, 2021
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: Guoqiang Li
  • System and Method for Focusing Color Schlieren Diagnostics
    Publication number: 20210080389
    Abstract: Embodiments of the present application are directed toward a focusing Schlieren technique that is capable of adding color-coded directional information to the visualization of density gradients. Other advantages of the technique can include that it does not require manual calibration, has a simple design and is sensitive enough to be used in compact experimental setups. Certain embodiments include the use of a color-coded source image that replaces the conventional source grid. The technique may benefit from a computer-controlled digital background, which is used for both illumination and display of color-coded source images.
    Type: Application
    Filed: November 11, 2020
    Publication date: March 18, 2021
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: Ingmar SCHOEGL
  • Feral Hog Toxicant
    Publication number: 20210068398
    Abstract: A composition and method for killing feral hogs: a bait that is attractive to hogs is mixed with a lethal amount of sodium nitrite, along with sufficient base to inhibit decomposition of the sodium nitrite. At sufficiently high pH, encapsulation of the sodium nitrite is not required to inhibit decomposition. In the absence of substantial decomposition, the sodium nitrite itself is not aversive to the pigs, and may even enhance acceptance of the baits by the pigs. Optionally, an anti-emetic compound is added to the mixture to reduce the likelihood the bait will be vomited. Optionally, an additional toxicant such as luteolin is added to the mixture.
    Type: Application
    Filed: August 24, 2020
    Publication date: March 11, 2021
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Glen Gentry, John Pojman, Baylen Thompson
  • HIGH-STRENGTH CONCRETE-LIKE FLUOROGYPSUM-BASED BLENDS AND PRODUCTION METHOD
    Publication number: 20210061713
    Abstract: High-strength concrete-like FG blends and methods for producing them are described. The blend includes FG, hydraulic cement, additional alkali material, and pozzolanic material. The blend further includes an admixture used in the formulation of concrete. The blend further includes an aggregate. The aggregate is a coarse aggregate or a fine aggregate.
    Type: Application
    Filed: November 12, 2020
    Publication date: March 4, 2021
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Michele Barbato, Yasser Bigdeli, Maria Teresa Gutierrez-Wing, Charles Davis Lofton
  • PHASE CONTRAST X-RAY INTERFEROMETRY
    Publication number: 20210065924
    Abstract: A phase contrast X-ray imaging system includes: an illumination source adapted to illuminate a region of interest; a diffraction grating adapted to receive illumination from the illuminated region of interest, the diffraction grating comprising a spatial structure having a first periodicity superimposed with a second periodicity that is different from the first periodicity; and a detector adapted to detect illumination passing through the diffraction grating, wherein the spatial structure is defined by varying height and/or pitch, and wherein the spatial structure imparts a first phase dependence based on the first periodicity and an additional phase dependence based on the second periodicity on the illumination passing through the diffraction grating.
    Type: Application
    Filed: November 13, 2020
    Publication date: March 4, 2021
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Joyoni Dey, Narayan Bhusal, Leslie Butler, Jonathan P. Dowling, Kyungmin Ham, Varshni Singh
  • Composition and method of making two-way shape memory polymer based sealant
    Patent number: 10934381
    Abstract: A sealant composition and method for its manufacture are disclosed. A two-way shape memory polymer (2W-SMP) sealant expands upon cooling and contracts upon heating, and thus provides improved sealing for pavements and other structures. The base resin for the sealant is polybutadiene with a high cis content. Uses for the sealant include, but are not limited to: sealant for expansion joint, contraction joint, or construction joint in cement concrete pavement; sealant or sealer for transverse cracks or block cracks in cement concrete pavement or asphalt concrete pavement; sealant for pipelines, lightweight composite structures, roofs, buildings, bridge decks, dams, offshore platforms; sealant for other structures and devices that have previously typically used polymer sealants.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: March 2, 2021
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Lu Lu, Jinbao Cao, Guoqiang Li