Patents Assigned to The University of Sydney
  • Publication number: 20160128491
    Abstract: A combination child carrier and stroller including a stroller (12; 200) having a frame to which is secured wheels; and a child carrier (14; 216) having a saddle-like seating arrangement in which a child is to be seated vertically is provided. The child carrier is configured to be releasably secured to the stroller. Additionally, the child carrier 5 includes a child harness assembly (44; 216) and a carrier harness assembly (50; 226), the child harness assembly including a back support and a child safety harness (64), while the carrier harness assembly includes a carrier frame structure (42) and shoulder straps (46) secured to the frame structure, in order to carry the child carrier on the back of a caregiver. The child harness assembly and the carrier harness assembly are 10 configured to be releasably secured to each other to form a backpack child carrier (14).
    Type: Application
    Filed: July 11, 2014
    Publication date: May 12, 2016
    Applicant: The University of Sydney
    Inventors: Alexandra Martiniuk, Roman Podrouzek, Milles Park, Elizabeth Slater
  • Patent number: 9320755
    Abstract: The present invention relates to methods for modulating angiogenesis, comprising administering to a subject, or cells or tissue derived therefrom: (i) one or more miRNA, or precursors or variants thereof, wherein at least one of said miRNA comprises a seed region comprising the sequence UCACAGU (SEQ ID NO:37) to inhibit angiogenesis; or (ii) one or more antagonists of a miRNA, wherein said miRNA comprises a seed region comprising the sequence UCACAGU (SEQ ID NO:37) to promote or induce angiogenesis. Also provided are methods of diagnosis of conditions associated with abnormal angiogenesis, or determining predisposition thereto. Suitable pharmaceutical compositions are also provided.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: April 26, 2016
    Assignees: CENTENARY INSTITUTE OF CANCER MEDICINE AND CELL BIOLOGY, UNIVERSITY OF SYDNEY, WENKART FOUNDATION
    Inventors: Jennifer Gamble, Mathew Vadas, Gregory Goodall, Jennifer Young
  • Publication number: 20160106762
    Abstract: The present disclosure provides compositions that include a nanoparticle and a compound that increases the biological activity of the vitamin D receptor (VDR) (e.g., a VDR agonist), and methods of using such compounds to increase retention or storage of vitamin A, vitamin D, and/or lipids by a cell, such as an epithelial or stellate cell. Such methods can be used to treat or prevent fibrosis.
    Type: Application
    Filed: October 23, 2015
    Publication date: April 21, 2016
    Applicants: Salk Institute for Biological Studies, The University of Sydney
    Inventors: Ning Ding, Michael Downes, Christopher Liddle, Ronald M. Evans
  • Patent number: 9297256
    Abstract: Methods and systems are described for generating a data representation of a geographical region as an adjunct to conducting autonomous operations within the region. The method comprises receiving information specifying a plurality of localized caused zones having operation-defined geographical boundaries within the region; receiving heterogeneous data descriptive of the region; associating the received data with respective localized zones; fusing the received data associated with the localized zones into data representations of the localized zones; and integrating the data representations of the localized zones into a common data representation of the geographical region.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: March 29, 2016
    Assignee: The University of Sydney
    Inventors: Eric Nettleton, Ross Hennessy, Hugh Durrant-Whyte, Ali Haydar Göktogan, Peter James Hatherly, Fabio Tozeto Ramos
  • Patent number: 9255198
    Abstract: The invention provides a method of preparing an aqueous dispersion of polymer encapsulated particulate material, the method comprising: providing a dispersion of the particulate material in a continuous aqueous phase, the dispersion comprising RAFT agent as a stabiliser for the particulate material; and polymerising ethylenically unsaturated monomer under the control of the RAFT agent to form polymer at the surface of the dispersed particulate material, thereby providing the aqueous dispersion of polymer encapsulated particulate material; wherein polymerisation of the ethylenically unsaturated monomer comprises: (a) polymerising a monomer composition that includes ionisable ethylenically unsaturated monomer so as to form a base responsive water swellable RAFT polymer layer that encapsulates the particulate material; and (b) polymerising a monomer composition that includes non-ionisable ethylenically unsaturated monomer so as to form an extensible, water and base permeable RAFT polymer layer that encapsulate
    Type: Grant
    Filed: December 1, 2010
    Date of Patent: February 9, 2016
    Assignee: The University of Sydney
    Inventors: Matthew P. Baker, Timothy W. Davey, Brian S. Hawkett, Duc N. Nguyen, Caitlin C. O'Brien, Christopher H. Such
  • Publication number: 20160022869
    Abstract: The invention relates to an activated metallic, semiconductor, polymer, composite and/or ceramic substrate, the substrate being bound through a mixed or graded interface to a hydrophilic polymer surface that is activated to enable direct covalent binding to a functional biological molecule, the polymer surface comprising a sub-surface that includes a plurality of cross-linked regions, as well as to such activated substrates that have been functionalised with a biological molecule and to devices comprising such functionalised substrates. Such substrates can be produced by a method comprising steps of: a.
    Type: Application
    Filed: October 1, 2015
    Publication date: January 28, 2016
    Applicant: THE UNIVERSITY OF SYDNEY
    Inventors: Marcela Bilek, David McKenzie, Yongbai Yin
  • Publication number: 20160018417
    Abstract: The invention relates to methods and assays for identifying compounds as candidates in the development of a drug for the treatment of various diseases including those associated with pathological Tau. The invention also relates to methods and assays for identifying compounds for the treatment of various diseases including those associated with pathological Tau. The invention also relates to cell lines and constructs for use in an assay of the invention. The methods and assays identify a compound as useful in the treatment of a tauopathy if said compound modulates Sil1 expression or activity.
    Type: Application
    Filed: March 6, 2014
    Publication date: January 21, 2016
    Applicant: THE UNIVERSITY OF SYDNEY
    Inventors: Lars Matthias ITTNER, Janet VAN EERSEL
  • Patent number: 9224050
    Abstract: Described herein is a method and system for vehicle localization in an open pit mining environment having intermittent or incomplete GPS coverage. The system comprises GPS receivers associated with the vehicles and providing GPS measurements when available, as well as one or more cameras 50,55 overlooking the mine region 10. The cameras 50,55 are at a known location and are used for generating a sequence of images in a field of view with predetermined calibration in a fixed coordinate system. The system further comprises a vehicle recognition processor 120 for analyzing individual images from the camera to identify and locate within an image a vehicle in the mine region, as well as a vehicle tracking processor 130 for analyzing a sequence of images from the camera to track the identified vehicle location in the sequence of images.
    Type: Grant
    Filed: March 16, 2011
    Date of Patent: December 29, 2015
    Assignee: The University of Sydney
    Inventors: Pantelis Elinas, Linthotage Dushantha Lochana Perera, Eric Nettleton, Hugh Durrant-Whyte
  • Patent number: 9220806
    Abstract: The present invention relates to a biocompatible material and in particular to a two-phase or composite biocompatible ceramic material, wherein the first phase is a doped calcium zinc silicate and the second phase is a metal oxide. In an embodiment, the invention has been developed for use in tissue regeneration including bone tissue. In other embodiments, the invention has been developed as a coating to improve the long-term stability of prior art implantable medical devices.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: December 29, 2015
    Assignee: The University of Sydney
    Inventors: Hala Zreiqat, Seyed-Iman Roohani-Esfahani, Colin Dunstan, Jiao Jiao Li
  • Publication number: 20150343037
    Abstract: The invention relates generally to the field of bone diseases. More specifically, the invention relates to methods and compositions for the treatment of osteoporosis and related disorders.
    Type: Application
    Filed: September 13, 2012
    Publication date: December 3, 2015
    Applicants: NEPEAN BLUE MOUNTAINS LOCAL HEALTH DISTRICT, THE UNIVERSITY OF SYDNEY
    Inventors: Gustavo Duque, Christopher Vidal
  • Patent number: 9199849
    Abstract: A process for producing nitric acid is disclosed in which a gaseous oxidizer feed composed at least substantially of ammonia, steam and an oxidizing gas is exposed to conditions whereby the ammonia is oxidized to produce a reaction mixture including nitrogen monoxide and water vapor. The reaction mixture is then cooled in a heat exchanger whereby: a) the nitrogen monoxide is oxidized and the water vapor is caused to condense, b) the products of the nitrogen monoxide oxidation react with and are absorbed by the condensed water, and c) substantially all of the nitrogen monoxide in the reaction mixture is converted to nitric acid. Also disclosed is a nitric acid solution when produced by the disclosed process.
    Type: Grant
    Filed: December 1, 2011
    Date of Patent: December 1, 2015
    Assignees: ORICA INTERNATIONAL PTE LTD, THE UNIVERSITY OF SYDNEY
    Inventors: Anthony Matthew Johnston, Brian Scott Haynes
  • Publication number: 20150319943
    Abstract: Disclosed herein is a plant watering device (10) comprising a vessel, for example a tube (14), arranged to be fastened to at least one plant propagule. The tube 14 is further arranged such that when the at least one propagule (18) is so fastened water received by the tube (14) is drawn by the at least one propagule (18) through a portion of the tube (14).
    Type: Application
    Filed: February 4, 2012
    Publication date: November 12, 2015
    Applicants: NEWSOUTH INNOVATIONS PTY LIMITED, THE UNIVERSITY OF SYDNEY
    Inventors: Gregory Lawrence Leslie, Bruce Gregory Sutton, Alice Antony
  • Publication number: 20150299691
    Abstract: The invention relates to structures for the immobilisation and protection of organic molecules, in particular, functional biological molecules. In one aspect the invention provides a structure comprising a substrate having a nanostructured spacer on a surface thereof; and an organic molecule immobilised on the surface of the substrate. Structures of the invention have a variety of potential utilities, including in protection of catalysts used in continuous flow, in medical devices and in protection of ligands for the binding of analytes in biosensors and diagnostic devices.
    Type: Application
    Filed: November 22, 2013
    Publication date: October 22, 2015
    Applicant: THE UNIVERSITY OF SYDNEY
    Inventors: Aleksey Kondyurin, Marcela Bilek
  • Patent number: 9156916
    Abstract: Provided herein are methods for modulating one or more of a T-helper cell or monocyte lineage cell-mediated immune response in a subject, the method comprises administering to the subject an effective amount of a compound which binds to surface membrane immunoglobulin D (smIgD). Also provided are methods of diagnosis of one or more of a T-helper cell or monocyte lineage cell-mediated immune disease, and compositions and kits for use in such methods.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: October 13, 2015
    Assignees: The University of Sydney, Northern Sydney and Central Coast Area Health Service
    Inventors: Tue G. Nguyen, Jonathan M. Morris, Eileen D. M. Gallery, Sharon McCracken
  • Publication number: 20150276767
    Abstract: Systems and methods for identifying tumors having activated progesterone receptors are provided. Patients suspected of having a tumor susceptible to growth inhibition by anti-progestins can be treated with an anti-progestin.
    Type: Application
    Filed: March 11, 2015
    Publication date: October 1, 2015
    Applicant: THE UNIVERSITY OF SYDNEY
    Inventors: Christine L. CLARKE, J. Dinny GRAHAM
  • Patent number: 9146553
    Abstract: A hierarchical control system (203) for supervising operations of an autonomous operator located within a defined geographical region containing a localized zone having an operation-defined boundary. The control system (203) has a primary controller (604) associated with the defined geographical region and a secondary controller (605) associated with the localized zone. The secondary controller (605) is responsive to the supervisory control of the primary controller (604). The autonomous operator, if located within the localized zone, is responsive to the supervisory control of the secondary controller (605).
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: September 29, 2015
    Assignee: The University of Sydney
    Inventors: Eric Nettleton, Ross Hennessy, Hugh Durrant-Whyte, Ali Haydar Göktogan, Surya P N Singh
  • Patent number: 9135510
    Abstract: Apparatus for and method of processing sensor data for the purpose of navigating a vehicle (for example an autonomous or semi-autonomous vehicle), the sensor data being from a sensor (for example a camera) mounted on the vehicle. The method can include can include: for a number of time-steps, measuring a value of a parameter of a scene using the sensor to produce a sequence of images of the scene; determining a value of one or more image quality metrics (for example, spatial entropy and spatial information) in each image in the sequence; and identifying as either valid or invalid, a sub-sequence of images in the sequence based on the determined metric values.
    Type: Grant
    Filed: August 24, 2011
    Date of Patent: September 15, 2015
    Assignee: UNIVERSITY OF SYDNEY
    Inventors: Thierry Peynot, Christopher Brunner
  • Patent number: 9129236
    Abstract: Forming a sequence plan for a machine to travel to a series of specified locations is described. An initial cost table (414) and a pattern of locations (412) is inputted to a Sequential Ordering Problem (SOP) solver (402). The resulting sequence (410) is processed by a motion planner (404) to derive by a motion planning procedure a plan of machine motions through the sequence. A cost table update (408) is performed based on the motion plan, which is then used for another iteration of the SOP solver (402).
    Type: Grant
    Filed: April 16, 2010
    Date of Patent: September 8, 2015
    Assignee: The University of Sydney
    Inventors: Pantelis Elinas, Surya P. N. Singh
  • Patent number: 9119805
    Abstract: The present invention provides methods for the therapy and prevention of problem drinking in alcohol-dependent and non-dependent subjects and those at risk of developing problem drinking behavior, and compositions of matter comprising oxytocin or an analog or derivative thereof or an agonist or partial agonist of an oxytocin receptor that are useful in preventing or treating problem drinking.
    Type: Grant
    Filed: September 29, 2010
    Date of Patent: September 1, 2015
    Assignee: THE UNIVERSITY OF SYDNEY
    Inventors: Iain Stewart McGregor, Dean Samuel Carson, Adam John Guastella, Michael Thomas Bowen
  • Patent number: 9113281
    Abstract: Equipment (10) for reconstructing a recorded sound field includes a sensing arrangement (12) for measuring the sound field to obtain recorded data. A signal processing module (14) is in communication with the sensing arrangement (12) and processes the recorded data for the purposes of at least one of (a) estimating the sparsity of the recorded sound field and (b) obtaining plane-wave signals to enable the recorded sound field to be reconstructed.
    Type: Grant
    Filed: October 6, 2010
    Date of Patent: August 18, 2015
    Assignee: THE UNIVERSITY OF SYDNEY
    Inventors: Craig Jin, Andre van Schaik, Nicolas Epain