Abstract: Apparatus for use in four wave mixing is disclosed, comprising a nonlinear medium for receiving a plurality of light beams copropagating along an optical path through the nonlinear medium, the plurality of light beams including at least one signal wave having a signal frequency and one or two pump waves having respective pump frequencies, the light beams generating one or more unwanted idler waves in the nonlinear medium. The apparatus further comprises phase adjusting means arranged to selectively apply to wavelengths of light in the nonlinear medium, respective wavelength-dependent phase shifts to adjust the phase difference between the or each pump wave and the signal wave, such that unwanted idler waves are generated along the optical path of the nonlinear medium so as to destructively interfere, suppressing unwanted idler waves at an output of the nonlinear medium. A method of configuring the phase adjusting means is disclosed.

Abstract: The present invention provides a piezoelectric speaker, including: a frame; a cantilever plate actuator disposed on the frame; a spring connected to the frame and the cantilever plate actuator; and a central diaphragm connected to the spring, wherein when the cantilever plate actuator vibrates, the central diaphragm vibrates with the spring.

Abstract: The present discloses systems and methods for tissue analysis, biopsy, and treatment utilizing at least exogenous fluorophores and near infrared light. A method is disclosed for optically determining the presence of abnormal cells, such as cancer, in tissue. The method includes applying one or more exogenous fluorophores into tissue in an animal body, wherein the exogenous fluorophores include a targeting moiety formulated to bond with a selected site on abnormal cells. The method includes illuminating the one or more exogenous fluorophores in the tissue with near infrared light from an elongated optical probe to generate fluorescent light from exogenous fluorophores present in the tissue. The method includes receiving fluorescent light generated from the one or more exogenous fluorophores in the tissue. The method includes determining if abnormal cells are present in the tissue based on the fluorescent light generated from the one or more exogenous fluorophores in the tissue.

Abstract: The filter for carbon dioxide adsorption according to the present invention is composed of multiple unit filters that are mutually connected and stacked, and the unit filters include a repeating three-dimensional patterned part formed using one selected from vat photopolymerization, powder bed fusion, or additive manufacturing processes; flow paths formed in the three-dimensional patterned part; a three-dimensional exposed surface that is exposed to the mixed gas flowing through the flow paths; and a carbon dioxide adsorption layer coated on the exposed surface.

Abstract: In accordance with an embodiment, a noise reduction device includes a housing; and a slit located inside the housing and having a unit cell located therein, the unit cell comprising a sound absorbing layer configured to absorb noise generated from a sound source inside the housing, and a meta-material panel layer located on one surface of the sound absorbing layer, the meta-material panel layer comprising a sound meta-material.

Abstract: Disclosed is a perovskite light-emitting device with reduced defects in a perovskite thin film. The passivation layer in the perovskite light-emitting device is formed on the upper part of the perovskite thin film to eliminate defects in the perovskite nanocrystalline particles and resolve charge imbalance in the device, thereby improving maximum efficiency and maximum luminance of the light-emitting device.

Abstract: A hard optical film, a method for producing the same and use thereof. The film is an optical film with a nano-dual-phase structure, and features a regulable thickness, high visible light transmittance and hardness, a flat and uniform surface, and a great application prospect. The hard optical film is prepared on a surface of a substrate by magnetron sputtering, having high binding force between the obtained film and the substrate, such that the substrate has a very high hardness, a very strong abrasion resistance and certain corrosion resistance.

Abstract: Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.

Abstract: Methods and compositions are provided for activating transcription in a mammalian cell.

Abstract: A transparent photovoltaic cell is proposed. The transparent photovoltaic cell may include a transparent substrate, a plurality of micro-pillars arranged on an upper part of the transparent substrate and formed with respective transparent windows, through which incident sunlight transmits, on respective upper parts thereof. The transparent photovoltaic cell may also include a photoelectric converter formed on an upper surface of the transparent substrate between each of the plurality of micro-pillars and on side surfaces of each micro-pillar, and configured to generate power through absorption of incident sunlight.

Abstract: Provided are a polymer viscosity reducer for a water-based drilling fluid and a preparation method thereof. The polymer viscosity reducer for the water-based drilling fluid is prepared from raw materials including, in parts by mass: 100 parts to 150 parts of water, 30 parts to 50 parts of acrylic acid, 10 parts to 20 parts of maleic anhydride, 40 parts to 60 parts of allyl polyethylene glycol, 3 parts to 6 parts of an initiator, 1 part to 3 parts of a pH regulator, 10 parts to 20 parts of a diamine, and 5 parts to 10 parts of a saturated organic acid.

Abstract: Aspects of this disclosure relate to driving a capacitive micromachined ultrasonic transducer (CMUT) with a pulse train of unipolar pulses. The CMUT may be electrically excited with a pulse train of unipolar pulses such that the CMUT operates in a continuous wave mode. In some embodiments, the CMUT may have a contoured electrode.

Abstract: A code sequence based intelligent key code identification method includes extracting Smali code sequence by decompiling an application, vectorizing the extracted Smali code sequence to construct a training dataset, training a deep learning model with the vectorized Smali code sequence to generate a classifier, generating a category classification result using Smali code sequence of a target application as input of the classifier, and identifying and providing important Smali code sequence from which the classification result of the target application is derived. Accordingly, it is possible to objectively evaluate the application using Smali code sequence of the application being actually run.

Abstract: A UV-curable durable coating composition is described that forms a transparent, antismudge coating. The composition includes a photoinitiator, a di-, tri-, or multi-functional monomer that bears double bonds, epoxide groups, or a combination, and a graft copolymer that bears pendant double bonds, epoxide groups or a combination and bears PDMS, polyisobutyl or perfluorinated polyether side chains.

Abstract: In an aspect, a method for additive manufacture of a three-dimensional object based on a computational model comprises steps of: grayscale photohardening a precursor material to form a portion of the object; and applying a hardened meniscus coating at a feature of the object; wherein the three-dimensional object is formed via at least the combination of the steps of gray scale photohardening and applying the meniscus coating. In some embodiments, the grayscale photohardening step is a grayscale photopolymerization step. In some embodiments, the applying a hardened meniscus coating step is a meniscus equilibrium post-curing step.

Abstract: Methods and systems for sensing a physiological characteristic of a subject. At least one receiver antenna can be provided in proximity to a portion of the subject's body to obtain at least one receiver signal resulting from at least one transmitter signal that has propagated to the receiver antenna and has been reflected, diffracted, scattered, or transmitted by or through the portion of the subject's body. One or more coherent signal pairs can be formed. Then, amplitude and phase information of a plurality of frequency components for each signal pair can be determined. A set of comparison values can be determined for each signal pair by comparing respective frequency component phases and respective frequency component amplitudes of the signals. Physiological characteristics of the subject can then be determined from these comparison values.

Abstract: Provided herein are, inter alia, methods of identifying agents that are capable of inhibiting the binding (e.g., coupling) between a ROR1 protein and a ROR2 protein. By interfering with ROR1-ROR2 coupling (binding) the agents identified using the methods provided herein inhibit non-canonical Wnt5a signaling. Thus, the agents identified by the methods provided herein may, inter alia, be useful for cancer diagnosis and therapy.

Abstract: Foundry casting elements and methods of forming the same, the methods including: forming an aqueous slurry including an inorganic binder precursor, shaping the slurry using a pattern, curing the shaped slurry using a low temperature solidification process to form a casting element, and removing the pattern from the casting element.

Abstract: Three compounds having a common molecular template of 2-(5-(N-acylamino)pyridin-2-yl)-N-benzylacetamide (Compounds I, II and I) are identified as potential anticancer therapeutic agents, and for the treatment of Acute Myeloid Leukemia (AML) in particular. Compound I was specifically designed to target AML cells, inhibit growth, and induce cell death. Compound I demonstrated a dose-dependent effect on AML cell lines HL-60, Mv4-11, KG-1a, and K562.

Abstract: Embodiments described herein provide systems and methods to prevent, or provide a countermeasure, to a co-existence attack, for example, that may occur in a Security Credential Management System (SCMS) where both regular butterfly key (RBK) protocol and unified butterfly key (UBK) protocol are supported. Embodiments described herein provide, support, employ, or implement hardware acceleration for a Hardware Security Module (HSM), for example, for cryptographic operations (e.g., block ciphers, digital signature schemes, and key exchange protocols).