Patents Assigned to The University
  • Patent number: 12285793
    Abstract: A forming device and a forming method for a part with a regular cross-section are provided, and relates to the technical field of metal member forming and manufacturing. A part to be formed is heated by a part heating temperature control assembly to obtain required microstructure evolution, so that the forming performance is improved. A temperature control die assembly can be heated by setting die heating assemblies, so that hot stamping, die quenching and stress relaxation can be carried out. The internal stress state of the part is controlled by an axial force control assembly.
    Type: Grant
    Filed: March 31, 2024
    Date of Patent: April 29, 2025
    Assignees: DALIAN UNIVERSITY OF TECHNOLOGY, AVIC MANUFACTURING TECHNOLOGY INSTITUTE
    Inventors: Kailun Zheng, Dechong Li, Lihua Du, Yujie Han
  • Patent number: 12288132
    Abstract: Aspects of the present disclosure describe techniques that involve an active stabilization of coherent controllers using nearby qubits. In an aspect, a quantum information processing (QIP) system for stabilizing phase damping in qubits is described that provides a first and a second qubit ion, measuring magnetic field fluctuations using the second qubit ion, and generates one or more magnetic fields based on the measured magnetic field fluctuations, the one or more magnetic fields being applied near the first qubit ion to cancel the magnetic field fluctuations to stabilize the phase damping of the first qubit ion. Another such QIP system performs provides a first and a second qubit ion, locks a local oscillator to a frequency reference associated with the second qubit ion, and tracks, using the local oscillator, a frequency of the first qubit ion based on the frequency reference. Methods associated with these QIP systems are also described.
    Type: Grant
    Filed: June 29, 2021
    Date of Patent: April 29, 2025
    Assignees: University of Maryland, College Park, Duke University
    Inventors: Jungsang Kim, Kenneth Brown, Christopher Monroe
  • Patent number: 12287028
    Abstract: The present disclosure describes innovations to improve the use of noncircular gear pairs in a transmission, e.g., an infinitely variable transmission. The noncircular gear pair includes a first noncircular gear with a first pitch curve; and a second noncircular gear with a second pitch curve. The first pitch curve includes a plurality of elliptical portions, and a curvature of the first pitch curve is positive along the entire first pitch curve; and wherein the second pitch curve is a conjugate of the first pitch curve.
    Type: Grant
    Filed: October 21, 2022
    Date of Patent: April 29, 2025
    Assignee: UNIVERSITY OF MARYLAND, BALTIMORE COUNTY
    Inventors: Weidong Zhu, Gang Li
  • Patent number: 12285545
    Abstract: Methods of regenerating vital tooth tissue in situ after endodontic therapy include introducing a hydrogel scaffold into a root canal of a tooth in a patient after native pulp has been removed from the root canal. The hydrogel scaffold may comprise a sponge scaffold, and can be acellular. The hydrogel scaffold can contain chemotactic, angiogenic, neurogenic, and/or immunomodulatory biofactors that cause infiltration of endogenous cells from the patient into the root canal. Alternatively, such biofactors/drugs can be administered to the patient separately from the hydrogel scaffold. The hydrogel scaffold can fill the periapical space of an abscessed root.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: April 29, 2025
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Juan M. Taboas, Herbert L. Ray, Jingming Chen, Patrick Eugene Donnelly, Tyler Swenson
  • Patent number: 12285450
    Abstract: A Lactiplantibacillus plantarum strain ZFM518 deposited under CCTCC NO: M 2022442 is provided. Also provided is a composition including the strain ZFM518. Further provided is a method of treating a subject infected by Klebsiella pneumoniae ZFM4 deposited under CCTCC NO: M 20221900, including administrating to the subject a composition comprising a therapeutically effective amount of a fermentation supernatant of the Lactiplantibacillus plantarum strain ZFM518.
    Type: Grant
    Filed: September 25, 2024
    Date of Patent: April 29, 2025
    Assignee: Zhejiang Gongshang University
    Inventors: Qing Gu, Yingjuan Zhang, Qingqing Zhou, Zhongdu Ye, Ping Li
  • Patent number: 12286508
    Abstract: A shape-memory polymer that is melt-recyclable with high processability and little performance loss, in contrast to known Crosslinked semicrystalline shape-memory networks that are capable of storing large amounts of elastic energy with negligible plastic deformation but as thermosets are not easily melt-processed or recycled. In examples herein, catalyst-free isocyanate chemistry is used to prepare two linear poly(caprolactone)s with bisurea hydrogen bonding groups periodically positioned along the main chain. Compared to an entangled poly(caprolactone) homopolymer of similar molecular weight, the segmented poly(bisurea)s exhibit minimal stress relaxation when elastically strained at identical conditions. Furthermore, the materials' single relaxation times indicate chain reptation, and at sufficient temperatures, disentanglement occurs rapidly enough to perform melt-processing.
    Type: Grant
    Filed: February 24, 2022
    Date of Patent: April 29, 2025
    Assignee: University of Rochester
    Inventor: Mitchell Anthamatten
  • Patent number: 12286627
    Abstract: The present invention discloses a method for preventing dsRNA bacterial solutions from being degraded by UV light and application thereof in control of silverleaf whiteflies which relates to technical field of pest control. The method for preventing dsRNA bacterial solutions from being degraded by UV light of present invention is to mix dsRNA bacterial solutions with nanomaterial solutions to prepare mixed solutions of nanomaterial as well as dsRNA bacterial solutions, wherein the nanomaterial is one of MON, Fe3O4, TiC and SiC. Nanomaterials are used to protect dsRNA bacterial solutions from being degraded by UV light, so that lethal effect of dsGawky on silverleaf whiteflies can achieve purpose of pest control. The method is easy to operate, low in cost, good in effectiveness as well as sensitivity, high in insecticidal efficiency, and has other advantages such as environmental friendliness as well as good application prospects.
    Type: Grant
    Filed: October 29, 2024
    Date of Patent: April 29, 2025
    Assignee: QINGDAO AGRICULTURAL UNIVERSITY
    Inventors: Dong Chu, Zhishao Cen, Lili Wang, Xinxi Ren, Yunli Tao
  • Patent number: 12285404
    Abstract: The disclosure demonstrates the role of mast cell stabilizers in treating rosacea. The disclosure also shows the role of mast cells, cathelicidin, serine protease and/or vitamin D3 in rosacea pathology and the use of antagonists and inhibitors thereof to treat rosacea.
    Type: Grant
    Filed: June 7, 2022
    Date of Patent: April 29, 2025
    Assignee: The Regents of the University of California
    Inventors: Richard L. Gallo, Anna Di Nardo, Yumiko Muto
  • Patent number: 12286348
    Abstract: An embodiment of the present invention provides a noble gas hydride having the following formula 1: NgnHm. In formula 1, Ng represents a noble gas atom, n represents an integer from 1-8, and m represents an integer from 1-46.
    Type: Grant
    Filed: July 6, 2020
    Date of Patent: April 29, 2025
    Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATION
    Inventor: Kazuo Watanabe
  • Patent number: 12286488
    Abstract: Disclosed is a hybridoma cell strain that secretes anti-dinitolmide monoclonal antibodies applicable to the field of food safety immunoassay methods. The hybridoma cell strain DAS3H10 that secretes anti-dinitolmide monoclonal antibodies has been deposited in Comprehensive Microbiology Center of China Microbial Culture Collection Management Committee (CGMCC), addressed in No. 1 Hospital No. 3 Institute of Microbiology of the Chinese Academy of Sciences, North Chenxi Road, Beijing Chaoyang District in Beijing. It is classified as a monoclonal cell strain. The deposit date is Nov. 28, 2019, and the deposit number is MCCC No. 19165. The monoclonal antibody secreted by the hybridoma cell strain DAS3H10 has a good affinity and high sensitivity to dinitolmide. Because of IC50 to dinitolmide up to 9.01 ng/mL, the monoclonal antibody could be used to prepare dinitolmide immunoassay kits and colloidal gold test strips, and can further provide a powerful means for detecting dinitolmide in animal-derived foods.
    Type: Grant
    Filed: July 6, 2021
    Date of Patent: April 29, 2025
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Chuanlai Xu, Jie Liu, Hua Kuang, Liguang Xu, Maozhong Sun, Liqiang Liu, Xiaoling Wu, Changlong Hao, Shanshan Song, Yongming Hu, Qiankun Zheng
  • Patent number: 12285453
    Abstract: A method for treating leukemia and in particular, lymphoblastic leukemia is provided. The method includes a step of administering an FMD to a subject identified as having leukemia optionally in combination with a chemotherapeutic agent and/or an autophagy inhibitor.
    Type: Grant
    Filed: December 1, 2021
    Date of Patent: April 29, 2025
    Assignee: University of Southern California
    Inventors: Valter D. Longo, Roberta Buono
  • Patent number: 12285580
    Abstract: This invention provides parasitic millirobots that can effectively adapt to an unstructured environment and coherently interact with diverse objects in order to fulfil various application needs. Particularly, a minimalist millirobot construction strategy by splashing composited agglutinate magnetic spray (M-spray) is adopted, which is capable of self-turning multifarious milli-/centi-objects into parasitic millirobots on-demand. Through taking full advantage of the objects' inherent structure and a covered thin drivable film, the M-spray demonstrates superior handling (from 1-D to 3-D structures) and loading capabilities (up to thousand-fold and hundred-fold of its volume and weight, respectively) while with neglectable size increment (as low as 1%) to target.
    Type: Grant
    Filed: December 13, 2021
    Date of Patent: April 29, 2025
    Assignee: City University of Hong Kong
    Inventors: Yajing Shen, Xiong Yang
  • Patent number: 12285737
    Abstract: Amine-supported mesoporous carbon and a preparation method and use thereof are provided.
    Type: Grant
    Filed: November 27, 2024
    Date of Patent: April 29, 2025
    Assignee: Zhejiang University
    Inventors: Minghui Tang, Hongxian Li, Shengyong Lu, Qi Liu, Zhiyuan Gong, Jianhua Yan
  • Patent number: 12286354
    Abstract: A method for manufacturing a humidity alarm device based on laser-induced graphene is performed as follows. Carbon-based films are coated with a hydroxide ion-containing solution and processed by a laser device to generate hydrophilic graphene layers. The hydrophilic graphene layers are peeled off from the carbon-based films, wetted, and respectively wrapped around shaping rods varying in diameter. The wrapped rods are heated and shaped by a drying oven to obtain curled graphene switches. Each curled graphene switch is connected in series with an alarm lamp to form an alarm component. The alarm components are connected in parallel, and then connected to a positive terminal and a negative terminal of a power supply to form the humidity alarm device.
    Type: Grant
    Filed: December 16, 2024
    Date of Patent: April 29, 2025
    Assignee: Guangdong University of Technology
    Inventors: Yun Chen, Bin Xie, Yuanhui Guo, Hao Zhang, Maoxiang Hou, Li Ma, Xin Chen
  • Patent number: 12289071
    Abstract: An induction machine with localized voltage unbalance compensation is disclosed. The use of an induction machine with a voltage unbalance correction compensator (VUC) may be used to maintain proper working conditions of the machine during intervals of voltage unbalance.
    Type: Grant
    Filed: August 18, 2023
    Date of Patent: April 29, 2025
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Thomas A. Lipo, Akihiro Imakiire
  • Patent number: 12285464
    Abstract: The present invention relates to methods and compositions for specifically modulating the Hippo pathway transcription factor TAZ (WWTR1), as a therapeutic target for inhibiting or preventing liver conditions including the progression of steatosis-to-NASH in a patient.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: April 29, 2025
    Assignees: The Trustees of Columbia University in the City of New York, The Brigham and Women's Hospital, Inc.
    Inventors: Ira Tabas, Xiaobo Wang, Omid Farokhzad, Xiaoding Xu
  • Patent number: 12288346
    Abstract: Methods, systems, and storage media are described for motion estimation in video frame interpolation. Disclosed embodiments use feature pyramids as image representations for motion estimation and seamlessly integrates them into a deep neural network for frame interpolation. A feature pyramid is extracted for each of two input frames. These feature pyramids are wrapped together with the input frames to the target temporal position according to the inter-frame motion estimated via optical flow. A frame synthesis network is used to predict interpolation results from the pre-warped feature pyramids and input frames. The feature pyramid extractor and the frame synthesis network are jointly trained for the task of frame interpolation. An extensive quantitative and qualitative evaluation demonstrates that the described embodiments utilizing feature pyramids enables robust, high-quality video frame interpolation. Other embodiments may be described and/or claimed.
    Type: Grant
    Filed: January 14, 2020
    Date of Patent: April 29, 2025
    Assignee: PORTLAND STATE UNIVERSITY
    Inventors: Feng Liu, Simon Niklaus
  • Patent number: 12286719
    Abstract: Disclosed are methods for direct electrodeposition of a metal from the liquid medium. The methods include electro-reduction of lithium anions on cathode electrodes in the presence of various metal deposition selectivity enhancements. The selectivity enhancement disclosed herein comprises the presence of a magnet, a solvent that is immiscible with an original liquid medium comprising the desired metal ions or various separators. Also disclosed are systems for electrodeposition of the desired metals from the liquid medium.
    Type: Grant
    Filed: April 26, 2022
    Date of Patent: April 29, 2025
    Assignee: Board of Regents, The University of Texas System
    Inventors: Thomas C. Underwood, Sheila Gerardo, Wen Song
  • Patent number: 12288584
    Abstract: A machine-readable medium and methods of reading and writing same are disclosed. The machine-readable medium comprises a substrate having an array of addressable locations thereon, each addressable location adapted to be physically associated with a collection of non-polymeric molecules. The molecules in each collection are selected from a set of unambiguously identifiable molecules, each molecule uniquely associated with a predetermined position in a numerical value, wherein the presence of the molecule in the collection indicates a predetermined digit at the associated position and the absence of said molecule in the collection indicates a zero at said associated position.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: April 29, 2025
    Assignees: President and Fellows of Harvard College, Northwestern University
    Inventors: George M. Whitesides, Brian J. Cafferty, Alexei S. Ten, Michael J. Fink, Daniel J. Preston, Milan M. Mrksich, Amit A. Nagarkar
  • Patent number: 12285357
    Abstract: Embodiments of the instant disclosure relate to intraocular drug delivery devices for and methods of, delivering at least one therapeutic agent to an eye of a subject. Methods include implanting an intraocular implant into the eye and adjacent to a fluid-permeable membrane of the eye of the patient. Intraocular implants are supported in a position at a surface of the fluid-permeable membrane. Intraocular implants include a drug delivery component having at least one therapeutic agent embedded within a non-bioerodible, non-biodegradable polymer matrix. Devices and methods disclosed herein can further include delivering the at least one therapeutic agent to the eye of the subject according to a near zero-order elution rate of the at least one therapeutic agent.
    Type: Grant
    Filed: July 20, 2023
    Date of Patent: April 29, 2025
    Assignees: SpyGlass Pharma, Inc., The Regents of the University of Colorado, a body corporate
    Inventors: Craig Alan Cable, II, Malik Y. Kahook, Ryan Absalonson, Glenn R. Sussman