Abstract: The present invention relates to a biomarker and uses thereof for liver cancer diagnosis or prognosis prediction. The biomarker according to the present invention may be used as a marker for liver cancer diagnosis and prognosis prediction with improved specificity and sensitivity. Thus, the biomarker may be used not only to diagnose or prognose liver cancer with high accuracy and reliability, but also to effectively screen a liver cancer treatment agent.

Abstract: An active energy ray-curable composition is disclosed including: an anionically polymerizable compound represented by (1): wherein EWG represents an electron-withdrawing group, X represents a single bond or an oxygen atom (—O—), R represents an n-valent organic group, and n represents an integer of 1 to 6; when n is an integer of 2 to 6, the respective EWG and the respective X may be the same or different; and when n is 1, EWG and R may be bonded; and a compound (photobase generator) represented by (2): wherein ring A represents an aromatic ring that may be substituted or a heteroaromatic ring that may be substituted; R1 and R2 are the same or different and each represents a hydrogen atom or an alkyl group; R1 and R2 may be bonded to each other to form a ring together with an adjacent nitrogen atom; and the ring may be substituted.

Abstract: Functional in vitro assays are provided for determining patient specific responsiveness to immunotherapy agents within a clinically actionable time frame.

Abstract: An apparatus to determine if a constituent member has been damaged. The constituent member can be a medical product comprising a coating, or a substance kneaded into the product, which emits a fluorescence in the near-infrared region. The apparatus to determine if this constituent member has been damaged includes an irradiation light source, an optical filter, an imaging unit, a display unit and a control unit connected to the light source, the optical filter and the imaging unit to determine and inform that damage has occurred in the constituent member.

Abstract: A dry adhesive includes a first plurality of fiber segments mechanically interlocked with a second plurality of fiber segments. A dry adhesive can include a first plurality of fibers mechanically interlocked with a second plurality of fibers or a single plurality of fibers having a first end region mechanically interlocked with a second end region. The fiber segments and fibers can be aligned, electrospun nanofibers. One or more continuous and scalable methods of making aligned fibers are also provided. One or more apparatuses are also provided.

Abstract: A Disease Severity Index (DSI) is provided for assessment of chronic liver disease in a patient using non-invasive liver function test results. A DSI was derived from non-invasive liver function test results based on hepatic blood flow. The DSI is used in methods for prediction of clinical outcomes, prediction of response to antiviral treatment, and assessment of progression of chronic liver diseases. Non-invasive methods to diagnose three distinct categories of patients with Primary Sclerosing Cholangitis (PSC) are provided. The methods can be used to diagnose PSC patients as Slow Progressors, Moderate Progressors and Rapid Progressors.

Abstract: Described are a genetically modified microorganism and corresponding methods and products. The genetically modified microorganism may include a first gene that encodes an acyl transferase and a second gene that encodes a peptide or protein. One or both of the first and second gene may be heterologous. The genetically modified microorganism may include a modified acyl-CoA biosynthetic pathway configured for one or more of: inducible biosynthesis of an acyl-CoA and over-accumulation of the acyl-CoA. The genetically modified microorganism may be effective upon fermentation to cause acylation of the peptide or protein by the acyl transferase using the acyl-CoA to provide a N-acylated peptide or protein product.

Abstract: A composite material comprising NiMoO4—CoMoO4 nanosheets can be an electrode in a hybrid supercapacitor. A hybrid supercapacitor having a cathode comprising the composite material exhibits a large operating window, high energy density and high cycling stability. The heterostructure material may be formed by a one-step chemical bath deposition process.

Abstract: A hybrid method and system for data encryption significantly reduces the computational cost of encryption and reduces the cost of the processors needed to perform encryption and decryption.

Abstract: Provided herein are microfluidic devices that can be configured to generate an electrophoretic flow that is in opposition to a fluid flow through a microcapillary of a microfluidic device provided herein. Also provided herein are methods that include adding an amount of particle to the inlet area of a microfluidic device as provided herein, generating a first fluid flow through a microcapillary of a microfluidic device provided herein; and applying a uniform electric field to the microfluidic device, where the uniform electric field generates an electrophoretic flow that is in opposition to the fluid flow.

Abstract: A gravity irrigation system includes a distribution piping having apertures to distribute water to a field, and a valve located upstream of the distribution piping. The valve limits a pressure of the water being delivered to the distribution piping. The system also includes a sump to receive the water at a lowest elevation of the field, a depth sensor disposed within the sump, and a return pump disposed at least partially within the sump to move the water to an elevated portion of the field. The system also includes a motor to drive the return pump, and a power source coupled to a variable frequency drive that powers the motor and controls a motor speed proportionately to an indication of the depth sensor. The system also includes a transfer piping to bring the water from the return pump to a check valve and to the distribution piping.

Abstract: This invention relates to the design and function of a compressible valve replacement prosthesis which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.

Abstract: A communications system provides for accurate fingerprinting of devices across a communications channel. A transmitter device modifies a physical layer signal prior to transmission as a function of signal modification parameters. A receiver device classifies a received physical layer signal and to outputs a classification indicator and a score. The receiver further analyzes the classification indicator and the score to produce an updated set of signal modification parameters provides the parameters to the transmitter device. The transmitter device, in turn, updates its signal modification parameters accordingly, thereby generating subsequent communications that more clearly indicate a fingerprint of the transmitter device.

Abstract: Three proteins, BCL-G (BCL2L14), CMPK2, and LAMP3, were discovered to independently restrict HIV-1 replication both in-vivo and in-vitro. Methods are described wherein subjects are given an effective amount of a pharmaceutical composition comprising a protein selected from the group consisting of BCL-G, CMPK2, LAMP3, functional parts thereof, recombinant proteins thereof, and combinations thereof, for the purpose of treating or preventing HIV.

Abstract: The present invention relates to a ball picking robot, comprising a walking mechanism, a ball picking mechanism, a ball pushing mechanism and a ball storage mechanism. The ball picking mechanism comprises a ball picking basket, an air cylinder used for driving the ball picking basket to move up and down, an air storage tank used for providing an air source for the air cylinder, a solenoid valve arranged at the air outlet of the air storage tank, a micro air pump connected to the air storage tank, and a shielding assembly arranged at an opening in the rear end of the ball picking basket. A first gear is mounted at the input end of the micro air pump. The ball pushing mechanism comprises a rotary ball discharging assembly, comprising an either-rotation motor, a rotary impeller connected to a first output shaft of the either-rotation motor through a belt assembly.

Abstract: A method, system, and apparatus for remote patient monitoring or tracking sepsis-related indicators or markers in ambulatory patients or outpatients. The method, system, and apparatus is devised or configured to provide remote patient monitoring of patient vitals signs for determining the risk for sepsis.

Abstract: Compositions and methods that utilize anti-CD11b antibodies, anti-CD18 antibodies, anti-myeloperoxidase (MPO) antibodies, anti-integrin ?V antibodies, anti-integrin ?1 antibodies, Abciximab, neutrophil inhibitory factor (NIF) protein, and/or combinations thereof to treat solid tumors are described.

Abstract: Medical devices having engineered mechanically functional cartilage from adult human mesenchymal stem cells and method for making same.

Abstract: Methods and software utilizing artificial neural networks (ANNs) to estimate density and/or flow (speed) of objects in one or more scenes each captured in one or more images. In some embodiments, the ANNs and their training configured to provide reliable estimates despite one or more challenges that include but are not limited to, low-resolution images, low framerate image acquisition, high rates of object occlusions, large camera perspective, widely varying lighting conditions, and widely varying weather conditions. In some embodiments, fully convolutional networks (FCNs) are used in the ANNs. In some embodiments, a long short-term memory network (LSTM) is used with an FCN. In such embodiments, the LSTM can be connected to the FCN in a residual learning manner or in a direct connected manner. Also disclosed are methods of generating training images for training an ANN-based estimating algorithm that make training of the estimating algorithm less costly.

Abstract: A method and system that includes a wearable device having a plurality of EEG sensors to detect an EEG signal in a window of a predetermined length, a bandpass filter to remove frequency bands of the EEG signal to obtain a combined signal of remaining frequency bands, and a wireless device connection for wireless transmission of information from the wearable device. The information including the EEG signal and the combined signal. A mobile device includes a communication device for receiving the transmitted information, at least one processor for processing a machine learning model. The machine learning model classifies the combined signal to obtain a classification result of mental stress or not mental stress, and a display device displays a mental stress assessment based on the EEG signal and the classification result.