Patents Assigned to The University
  • Patent number: 11180788
    Abstract: The present invention discloses a method for preparing lower graft degree GSGs, and belongs to the technical field of biosynthesis of sweeteners. The method uses amylase to catalyze hydrolysis of GSGs with a high graft degree, thereby obtaining GSGs with low graft degree mainly containing GSGs with a low grafting number. The content of mono- and di-glucosyl substituents in the SGs in the product was 60% or more of the total glycosides, and the mass percent of the GSGs with a glucosyl grafting number of 3 or less was higher than 70% of the total glycosides. The mono- and di-substituted GSGs obtained by enzyme catalysis by the present invention were structurally similar to those, belong to a mixture of the isomers thereof, and have good sweetness and a flavoring function.
    Type: Grant
    Filed: July 30, 2019
    Date of Patent: November 23, 2021
    Assignees: Jiangnan University, Dongtai Haorui Biotechnology Co., Ltd.
    Inventors: Yongmei Xia, Liping Zhu, Tongtong Zhang, Guoying Du, Xiang Liu, Yun Fang
  • Patent number: 11179428
    Abstract: A novel alga mutant having improved pigment productivity is provided. The mutant can be used to produce carotenoid-based pigments, particularly, xanthophyll by using a small amount of energy, and thus can effectively produce pigment on an industrial level. In addition, the mutant can be used as a source for foods, health functional foods, and medications which contain a pigment. Further, when account is taken of the physiological characteristics of the euryhaline microalgae Dunaliella and the geological characteristics of Korean, the three sides of which are in contact with the sea, sea-water can be used as a culture medium, with the expectation of reducing the cost and leading to the development of related industries.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: November 23, 2021
    Assignee: Industry-University Cooperation Foundation Hanyang University
    Inventors: Eon Seon Jin, Min Jae Kim
  • Patent number: 11180382
    Abstract: A process for removing lead from a liquid is provided. The liquid is brought into contact with PbrD proteins having an amino acid sequence which has at least 80% identity to SEQ ID NO: 2, and these proteins bind to lead ions present in the liquid, thus removing the lead ions from the liquid. The bound lead ions are subsequently recovered, such as in the form of an insoluble salt or compound or by cation exchange chromatography, and can then be recycled. The PbrD protein can be immobilized before being brought into contact with the liquid. The proteins are typically immobilized in a matrix of nanoparticles. The PbrD proteins can be recombinantly expressed, such as in a bacterial system (e.g. E. coli) or a yeast expression system.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: November 23, 2021
    Assignee: UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG
    Inventors: Kulsum Kondiah, Paul John Franklyn, Vidya Keshav
  • Patent number: 11183068
    Abstract: Various examples are provided related to multi-purpose context-aware bumps (CABs) that can support dynamic adaptation of form factors and functionality. In one example, a CAB system can include sensors distributed in a traffic network and communicatively coupled to a remotely located computing environment; context-aware bumps (CABs) placed in the traffic network and communicatively coupled to the remotely located computing environment; and a CAB application configured to adjust a form factor of a CAB in response to information obtained from the sensors and/or CABs. In another example, a method can include receiving, by a remotely located computing environment, traffic information from sensors distributed in a traffic network or CABs placed in the traffic network; communicating, by the remotely located computing environment, a form factor control to a CAB in response to the traffic information; and adjusting a form factor of the CAB in response to the form factor control.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: November 23, 2021
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Swarup Bhunia, Prabuddha Chakraborty, Lili Du, Sandip Ray
  • Patent number: 11184025
    Abstract: An LDPC decoding method of a received signal including a plurality of received symbols is provided. A decoding apparatus selects a perturbation space in which perturbation is to be performed based on a code length of the received signal and a maximum number of perturbation rounds indicating a number of perturbation rounds that can be performed, and performs a perturbation round. The decoding apparatus performs perturbation on a corresponding received symbol among the plurality of received symbols in each perturbation round, and decodes the received signal on which the perturbation has been performed. The decoding apparatus determines that decoding is successful when there is a perturbation round in which a decoding result of the received signal satisfies a predetermined condition.
    Type: Grant
    Filed: January 27, 2021
    Date of Patent: November 23, 2021
    Assignees: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE, RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY
    Inventors: Sang-Hyo Kim, Gi Yoon Park, Ok-Sun Park, Hyunjae Lee, Hyosang Ju, Jaesheung Shin
  • Patent number: 11181266
    Abstract: Disclosed is a method for calculating combustion in the bed of a waste incinerator. The method is based on a model of combustion in a waste incinerator bed and comprises a water evaporation model, a volatile matter analysis model, a volatile matter combustion model, and a fixed carbon combustion model. The volatile matter of the volatile matter combustion model comprises CO, H2, CH4, NH3, and H2S. The volatile matter combustion model comprises a combustion reaction equation for said volatile matter and O2, and respective equations for CO and CH4 reacting with water vapor. Equations governing the model of combustion in the bed of a waste incinerator comprise a continuity equation, an energy equation, a momentum equation, and a component equation. Boundary conditions of said governing equations comprise: equations of heat transfer and mass transfer from an upper boundary layer of the bed to the exterior; and equations of heat transfer and mass transfer from lower boundary layer of the bed to the exterior.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: November 23, 2021
    Assignee: TIANJIN UNIVERSITY
    Inventors: Guanyi Chen, Tianbao Gu, Wenchao Ma, Chen Ma, Li'an Hou, Beibei Yan, Bin Liu
  • Patent number: 11179342
    Abstract: Described herein is a composition for delivery of an active agent. The composition includes a peptide coacervate, wherein the peptide coacervate includes one or more peptides derived from histidine-rich proteins, and an active agent encapsulated in the peptide coacervate. Further provided are a method for encapsulation of an active agent in a peptide coacervate, a method for delivery of an active agent, and a method for treating or diagnosing a condition or disease in a subject in need thereof.
    Type: Grant
    Filed: June 20, 2019
    Date of Patent: November 23, 2021
    Assignee: NANYANG TECHNOLOGICAL UNIVERSITY
    Inventors: Ali Gilles Tchenguise Miserez, Yuan Ping, Zhi Wei Lim, Bartosz Piotr Gabryelczyk
  • Patent number: 11179374
    Abstract: The present invention includes compositions and methods for treating or preventing certain dermal disorders including dermal atrophy, pseudoscars, actinic keratosis, seborrheic or actinic keratoses, lentigines, focal areas of dermal thickening, and coarse wrinkles. In certain embodiments, the compositions useful within the invention comprise a therapeutically effective amount of a mTORC1 inhibitor and a dermatologically acceptable carrier.
    Type: Grant
    Filed: May 21, 2020
    Date of Patent: November 23, 2021
    Assignee: Drexel University
    Inventors: Christian Sell, Timothy Nacarelli, Ashley Azar
  • Patent number: 11181597
    Abstract: The present disclosure provides an operating method of an automatic analysis system on magnetic resonance imaging (MRI), which includes steps as follows. Images are received from of the subject's brain from the MRI machine. Contrast-enhanced T1-weighted images and T2-weighted images are obtained from the images, and the pre-processing is performed on the images. The ratio of T2-weighted images to contrast-enhanced T1-weighted images is calculated to generate contrast-enhanced images. The unsupervised clustering is performed on the region of interest in the contrast-enhanced image to separate a cystic part and a non-cystic part so as to calculate the feature parameters. After radiosurgery is performed on the brain tumor corresponding to the region of interest, the volume change of the tumor is analyzed. The linear regression analysis of the feature parameters and the volume change of the tumor is performed for prognostic evaluation.
    Type: Grant
    Filed: November 9, 2020
    Date of Patent: November 23, 2021
    Assignees: Taipei Medical University (TMU), TAIPEI VETERANS GENERAL HOSPITAL
    Inventors: Syu-Jyun Peng, Chih-Ying Huang, Cheng-Chia Lee, Huai-Che Yang, Hsiu-Mei Wu
  • Patent number: 11183596
    Abstract: Provided is a thin film transistor including a source electrode, a drain electrode, and a channel layer connecting the source electrode and the drain electrode. The channel layer includes a tin-based oxide represented by SnMO, wherein M includes at least one of a non-metal chalcogen element or a halogen element.
    Type: Grant
    Filed: November 6, 2019
    Date of Patent: November 23, 2021
    Assignee: IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY)
    Inventors: Jae Kyeong Jeong, Taikyu Kim, Baekeun Yoo
  • Patent number: 11179579
    Abstract: An image-guided radiation therapy apparatus comprises: a high-energy ray source configured for radiation therapy of an object; and a KV ray source, a first and second PET detectors, and a CT detector for KV CT and PET imaging for guiding the radiation therapy. The KV ray source is placed on, or at an inner or outer side of the first PET detector; the second PET detector and the CT detector are configured to receive the KV ray to perform KV CT imaging; the PET detectors are further configured to receive gamma ray emitted by the object to perform PET imaging.
    Type: Grant
    Filed: December 29, 2018
    Date of Patent: November 23, 2021
    Assignee: Tsinghua University
    Inventors: Hewei Gao, Zhiqiang Chen, Li Zhang, Yuxiang Xing
  • Patent number: 11180538
    Abstract: The invention provides a plasmid comprising two or more anti-obesity genes. Also provided by the invention are compositions and host cells comprising the plasmid and methods of increasing the metabolic activity in a mammal. The invention provides a plasmid comprising two or more of (a) a nucleic acid sequence encoding islet amyloid polypeptide (IAPP), (b) a nucleic acid sequence encoding leptin (LEP), and (c) a nucleic acid sequence encoding fibronectin type III domain containing 5 (FNDC5).
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: November 23, 2021
    Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: You Han Bae, Hongsuk Park, Sungpil Cho
  • Patent number: 11180816
    Abstract: The present invention relates to novel primers and sloppy molecular beacon and molecular beacon probes for amplifying segments from different genes in Mycobacterium tuberculosis for identifying the presence of M.tb DNA and/or resistance to anti-tuberculosis drugs.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: November 23, 2021
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: David Alland, Soumitesh Chakravorty
  • Patent number: 11180820
    Abstract: The present application provides a hot-work die steel and a preparation method thereof wherein the chemical constituents of the hot-work die steel in mass percentage are as follows: C: 0.20-0.32 wt %, Si: ?0.5 wt %, Mn: ?0.5 wt %, Cr: 1.5-2.8 wt %, Mo: 1.5-2.5 wt %, W: 0.5-1.2 wt %, Ni: 0.5-1.6 wt %, V: 0.15-0.7 wt %, Nb: 0.01-0.1 wt %, and a balance of iron, wherein an alloying degree is 5-7%; a tensile strength of the hot-work die steel at 700° C. is 560-700 MPa; a value of hardness of the hot-work die steel at room temperature is 32-38 HRC after holding at 700° C. for 3-5 h; and the hot-work die steel has an elongation of 14% to 16% at room temperature, a percentage reduction of area of 48% to 65%, and an impact toughness of 52-63 J at room temperature. The hot-work die steel of the present application has an excellent thermal stability as well as a good plasticity and a toughness at room temperature.
    Type: Grant
    Filed: September 15, 2020
    Date of Patent: November 23, 2021
    Assignee: University of Science and Technology Beijing
    Inventors: Jinfeng Huang, Jin Zhang, Cheng Zhang, Chao Zhao, Yong Lian, Jianqiang Li, Cheng Zhang
  • Patent number: 11181727
    Abstract: One aspect of the present disclosure relates to systems and methods that can be used for super-sensitivity multiphoton frequency-domain fluorescence lifetime imaging microscopy (MPM-FD-FLIM). One or more laser light sources can deliver excitation light with an intensity modulated by a periodic function to a sample, which includes a fluorophore concentration. A receiver can receive a fluorescence signal emitted from the fluorophore concentration over a time period. A computing device can transform the fluorescence signal to the frequency domain and measure a fluorescence lifetime associated with the sample in the frequency domain based on a DC component and at least one higher harmonic component generated by non-linear optical mixing of the modulated excitation light. Using the DC component and the at least one higher harmonic component can increase the sensitivity of an image created by the MPM-FD-FLIM system.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: November 23, 2021
    Assignee: UNIVERSITY OF NOTRE DAME DU LAC
    Inventors: Scott Howard, Genevieve Vigil, Yide Zhang
  • Patent number: 11183604
    Abstract: Provided is a field shaping multi-well photomultiplier and method for fabrication thereof. The photomultiplier includes a field-shaping multi-well avalanche detector, including a lower insulator, an a-Se photoconductive layer and an upper insulator. The a-Se photoconductive layer is positioned between the lower insulator and the upper insulator. A light interaction region, an avalanche region, and a collection region are provided along a length of the photomultiplier, and the light interaction region and the collection region are positioned on opposite sides of the avalanche region.
    Type: Grant
    Filed: October 1, 2020
    Date of Patent: November 23, 2021
    Assignee: The Research Foundation for The State University of New York
    Inventors: Amirhossein Goldan, Wei Zhao
  • Patent number: 11179065
    Abstract: Systems, methods and software products determine an overall motion and/or flexibility envelope for an individual. Movement and position data of the individual is captured and processed to generate an overall motion and/or flexibility envelope for the individual defining overall motion and/or flexibility of the individual. The systems include a flexibility server with memory and a processor adapted to receive movement and position data of the individual, a motion and/or flexibility analyzer, implemented as machine readable instructions stored in the memory and executed by the digital processor, capable of processing the movement and position data to generate an overall motion and/or flexibility envelope for the individual defining overall motion and/or flexibility of the individual.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: November 23, 2021
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
    Inventor: Marvin J. Slepian
  • Patent number: 11181874
    Abstract: The present invention discloses an N-1 static security analysis method for integrated energy system, including the following steps: constructing a static model of the IES including electro-gas-thermal coupling elements, calculating multiple energy flow equations, and calculating the multiple energy flow of the IES to obtain an operating status of the IES; constructing a N-1 preconceived accident set, calculating multiple energy flow of the IES, and performing security verification to the status of the coupling elements in each preconceived accident set, respectively; analyzing the security verification results by comparing the results of static security analysis under different control modes, so that an N-1 static security analysis is achieved. The present invention fully researches the security of the IES, comprehensively considers the influence of the output changes of the coupling elements on the operating point of the energy system, and evaluates the security and stability of the IES.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: November 23, 2021
    Assignee: NORTHEAST ELECTRIC POWER UNIVERSITY
    Inventors: Tao Jiang, Houhe Chen, Xue Li, Junyan Shao, Guoqing Li, Rufeng Zhang, Benxin Li, Changjiang Wang, Song Zhang, Shuguang Li, Xiaohui Li
  • Patent number: 11179493
    Abstract: The present disclosure relates to injectable compositions capable of forming a scaffold in situ at an intervertebral disc site, the composition comprising: (a) a biocompatible polymer; and (b) a biocompatible solvent system in sufficient amount to solubilize the biocompatible polymer in sufficient degree to allow injectable delivery to a disc site.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: November 23, 2021
    Assignee: Rowan University
    Inventors: Andrea Jennifer Vernengo, Thomas Richard Christiani, Cristina Iftode, Jennifer Kadlowec
  • Patent number: 11179411
    Abstract: An object of the present invention is to provide ASO that can effectively suppress a formation of RNA foci spontaneously occurring in neurons having SCA36 mutation, without inducing the cleavage of NOP56 pre-mRNA. The present invention provides an oligonucleotide comprising a nucleotide sequence in which one or more nucleotide sequences represented by SEQ ID NO: 2 are consecutively connected and is complementary to pre-mRNA of NOP56 gene, wherein a structure formed by the hybridization of the oligonucleotide to the pre-mRNA is resistant to RNaseH.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: November 23, 2021
    Assignee: KYOTO UNIVERSITY
    Inventors: Haruhisa Inoue, Keiko Imamura, Kosuke Matsuzono