Abstract: A method for preparing an electrowetting display support plate (5), comprising the following steps: preparing a substrate (7) having an electrode layer; preparing a hydrophobic insulating layer (13) and pixel walls (20) on the substrate (7) having an electrode layer, the pixel walls (20) being made of a hydrophilic material; performing plasma etching on the substrate (7) having the pixel walls (20), the power of the plasma etching being 30-1,000 W/m2; and heating the substrate (7) subjected to the plasma etching, so as to recover the hydrophobicity of the hydrophobic insulating layer (13). According to the method, the technical bias that the display support plate (5) being treated by means of the plasma etching would influence the quality of the hydrophobic insulating layer (13) is eliminated.

Abstract: Provided herein are compounds and methods for modulating the phosphodiesterase PDE4. More particularly, provided are selective inhibitors PDE4 and the uses of such inhibitors in regulating diseases and disorders, e.g., to treat cancer, inflammatory diseases, neurological diseases, neurodegenerative diseases, and addiction.

Abstract: The present invention relates to methods for producing immuno-stimulatory autologous dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from hyper-proliferative disease such as cancer.

Abstract: The disclosure provides compositions comprising peptide-based nanofiber precursors and methods of using the same to inhibit cancerous cell growth and/or to deliver therapeutic or diagnostic agents to cells, e.g., cancerous cells. The compositions of the present technology include peptide-based nanofiber precursors as well as carrier complexes comprising a therapeutic or diagnostic agent, and a peptide-based nanofiber precursor. Also provided herein are methods for delivering a therapeutic or diagnostic agent to a cell comprising contacting the cell with a carrier complex including a therapeutic or diagnostic agent, and a peptide-based nanofiber precursor.

Abstract: A method for preparing an organic complex microelement fertilizer for engineering wound soil remediation includes compounding chitosan oligosaccharide or/and earthworm dung or/and silkworm sand, water or/and hydrogen peroxide, an organic complex trace element solution, polyethylene glycol octyl phenyl ether, and polysorbate under certain conditions. The present invention can significantly improve physical and chemical properties of engineering wounds, enhance effectiveness of trace elements in soil, and prevent plant physiological diseases due to lack of trace elements, and promote plant growth and development.

Abstract: The present disclosure provides compositions and methods for increasing resistance to PCV2 infection in pigs. The increased resistance may be the result of siRNA or genetic modification through CRISPR or a vectored virus targeting SNPs that are resistant to PCV2 infection.

Abstract: A method for sequentially encrypting and decrypting doubly linked lists based on double key stream ciphers comprises: establishing a plaintext set M according to a plaintext file; using the plaintext set M as an initial value and performing iterative decryption to obtain a ciphertext set C, wherein a key set P and an algorithm set A are used during the iterative decryption; for the ciphertext set C, performing multiple decryptions by calling the key set P and keys in the key set P, wherein a key set P and an algorithm set A are used during the decryptions; and, converting the obtained result of decryption into a plaintext file.

Abstract: A solenoid valve includes a main valve, a first auxiliary valve, a second auxiliary valve, a main valve body, and an auxiliary valve body. The main and auxiliary valve bodies are axially parallel and detachably connected. The main valve is mounted on the main valve body, the first and second auxiliary valves are mounted on the auxiliary valve body, which is provided with an air inlet, a cylinder port and an air discharging port. The air inlet communicates with the main valve through a first air passage. The cylinder port is sequentially in communication with the first and second auxiliary valves and the main valve through a second air passage. The air discharging port sequentially communicates with the first and second auxiliary valves and the main valve through a third air passage. The main and second auxiliary valves are solenoid valves. The first auxiliary valve is a hand-operated valve.

Abstract: Various aspects of a systems and method for place recognition based on a 3D point cloud are disclosed herein. A computer-implemented method for place recognition based on a 3D point cloud, comprising: capturing a 3D point cloud of an area in which the mobile agent is traveling; extracting local features of each point in the captured 3D point cloud; generating a global descriptor of each point of the 3D point cloud using a deep neural network, based on the extracted local features; constructing a place descriptor map of the area based on the generated global descriptors; and recognizing the area by using the generated place descriptor map.

Abstract: A film comprising a first plurality of voids is provided, wherein respective ones of the first plurality of voids have a regular n-gon geometry, and the first plurality of voids are arranged on a regular n-gon lattice having a first size. The film may comprise a second plurality of voids arranged on a regular n-gon lattice having a second size different from the first size. An optical element and manufacturing method are also provided.

Abstract: A pressure regulator module for a chip-based microfluidic platform is provided. The module includes a microfluidic channel for passing flowable material from the inlet region through the outlet region and into a downstream compartment; one or more microvalves fluidly connected to the microfluidic channel and upstream of the outlet region; and one or more reservoirs fluidly connected to the microvalves, for receiving flowable material diverted by the microvalves, where a flow of flowable material passing from the inlet region toward the downstream compartment is at least partially diverted by the microvalves into the reservoirs as a result of a pressure increase in the microfluidic channel. In some versions, the microvalves are capillary burst valves. A microfluidic chip containing the module and a method of using the module are provided.

Abstract: An electromagnetic semi-continuous device comprises a crystallizer frame, an internal sleeve, a primary cooling water cavity, a secondary cooling water cavity and a tertiary cooling water cavity. An electromagnetic semi-continuous casting method comprises the steps of (1) adjusting angles of the adjustable spherical nozzles; (2) inserting a dummy bar head in a bottom of the internal sleeve; (3) feeding cooling water to the primary cooling water cavity and the secondary cooling water cavity, then spraying the cooling water to form primary cooling water and secondary cooling water, and exerting a magnetic field on the internal sleeve; (4) pouring the melts into the internal sleeve, starting the dummy bar head, and beginning to perform continuous casting; and (5) spraying tertiary cooling water through the tertiary cooling water cavity, so that casting billets reduce temperature until the continuous casting is completed.

Abstract: A catalyst for an oxychlorination process of hydrocarbons, a preparation method thereof, and a method for preparing an oxychlorination compound of hydrocarbons using the same.

Abstract: Methods of imaging described herein comprises disposing a first and second ultrasound-switchable fluorophore in an environment; exposing the environment to an ultrasound beam to create an activation region; disposing the first and/or second fluorophore within the activation region to switch the first and/or second fluorophore from an off state to an on state; exposing the environment to a beam of electromagnetic radiation; detecting a first photoluminescence signal at a first location within the environment, the photoluminescence signal comprising at least one of a first ultrasound fluorescence signal emitted by the first fluorophore, a first fluorescence signal emitted by the second fluorophore, and a background signal; correlating the first photoluminescence signal with a first reference signal to generate a correlation coefficient for the first location; and multiplying the first photoluminescence signal by the first correlation coefficient for the first location to generate a first modified photoluminesce

Abstract: The disclosure relates to compounds and compositions for bone formation, fracture treatment, bone grafting, bone fusion, cartilage maintenance and repair and methods related thereto. In certain embodiments, the disclosure relates to compositions comprising one or more compound(s) disclosed herein, such as clotrimazole, honokiol, magnolol, tacrolimus, pimecrolimus, sirolimus, everolimus, temsirolimus, spironolactone, fluticasone, fluticasone propionate, fluticasone furoate, linezolid, telmisartan, chlorambucil, retinol, isotretinoin, acitretin, etretinate, retinoic acid (tretinoin), teniposide, mitomycin C, cytarabine, decitabine, vinblastine, vincristine, vindesine, vinorelbine, valrubicin, doxorubicin, daunorubicin, epirubicin, idarubicin, mitoxantrone, pixantrone, plicamycin, pazopanib, topotecan, camptothecin, irinotecan, sunitinib, derivatives, or salt thereof, for use in bone growth processes.

Abstract: A corrosion inhibitor composition, which includes (i) a date palm leaves extract, (ii) a benzimidazole compound having at least one a carbamate group, (iii) a pyridine compound, (iv) a thiourea compound, (v) a cinnamaldehyde compound, (vi) a metal iodide, (vii) urotropin, and (viii) a base fluid containing an alcohol and an organic acid. A method of inhibiting corrosion of metal during acid cleaning is also disclosed, whereby the metal is treated with an acidic treatment fluid containing 1 to 5 wt. % of an acid, based on a total weight of the acidic treatment fluid, and 0.1 to 5 vol. % of the corrosion inhibitor composition, based on a total volume of the acidic treatment fluid.

Abstract: A desalination system includes a distillation unit to which a fluid to be desalinated is provided and through which a heat transfer fluid flows, and a solar concentration unit configured to heat the heat transfer fluid. The solar concentration unit includes an array of linear Fresnel reflectors, each linear Fresnel reflector of the array of linear Fresnel reflectors rotating about a respective axis, a receiver configured for absorption of light redirected by the array of linear Fresnel reflectors, the receiver comprising tubing through which the heat transfer fluid flows, and a frame supporting and positioning the receiver relative to the array of linear Fresnel reflectors. The frame defines a track along which the receiver is movable to adjust a relative position of the receiver along the respective axis of each linear Fresnel reflector of the array of linear Fresnel reflectors.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating bone diseases comprising a fusion peptide in which a bone tissue-selective peptide bound to parathyroid hormone (PTH) or a fragment thereof. More particularly, the present invention relates to a pharmaceutical composition and biomaterial for preventing or treating bone diseases comprising a fusion peptide in which a bone tissue-selective peptide represented by an amino acid sequence of SEQ ID NO. 3 bound to parathyroid hormone (PTH) or a fragment thereof represented by an amino acid sequence of SEQ ID NO. 4 or 5. The fusion peptide can improve effects of PTH by selectively binding to bone tissue and can reduce administration frequency by increasing the half-life. The fusion peptide can be used as a subcutaneous or intravenous injection-type pharmaceutical composition for treating osteoporosis and fracture, and can be used in combination with a medical device for tissue recovery to increase formation of bone tissue.

Abstract: The present invention provides dioxetane-based chemiluminescence probes, more specifically fluorophore-tethered dioxetane-based chemiluminescence probes and compositions thereof. The chemiluminescence probes disclosed are useful for both diagnostics and in vivo imaging.

Abstract: The present disclosure provides compositions and methods for labeling a single stranded target nucleic acid. Subject compositions include a Cas9 protein, a Cas9 guide RNA, and a quenched PAMmer. A subject quenched PAMmer is a single stranded oligonucleotide having (i) a protospacer adjacent motif (PAM) sequence; (ii) a detectable label; (iii) a quencher moiety that quenches the detectable label; and (iv) at least one of: a specificity segment positioned 5? of the PAM sequence, and an orientation segment positioned 3? of the PAM sequence. In the subject methods, the Cas9 protein cleaves the quenched PAMmer at a cleavage site positioned between the detectable label and the quencher moiety to produce: (a) a first cleavage product that is hybridized with the target nucleic acid and comprises the detectable label; and (b) a second cleavage product that is not hybridized with the target nucleic acid and comprises the quencher moiety.