Abstract: A method for optimization of photonic devices is disclosed. The method includes receiving a set of unconstrained latent variables; mapping the set of unconstrained latent variables to a constrained space to generate a constrained device; calculating the permittivity across each element of the constrained device; determining a permittivity-constrained width gradient based at least partially on the permittivity across each element; and optimizing the set of unconstrained latent variables by at least partially using the permittivity-constrained width gradient.

Abstract: A biomedical device includes a zinc-based material including a matrix including zinc, and nanostructures dispersed in the matrix. Embodiments of this disclosure are directed to zinc (Zn)-based materials including dispersed nanostructures for biomedical applications and devices, such as bioresorbable vascular stents, bioresorbable ureteral stents, endoluminal springs for distraction enterogenesis, biodegradable bone implants with tunable modulus, guided bone generation membranes, bioresorbable dental membranes, and other biomedical implants, as well as other functional applications, such as biodegradable electronics and sensors.

Abstract: An under-driven prosthetic hand with a self-adaptive grasping function is provided, which belongs to the field of medical equipment. The prosthetic hand simultaneously controls four fingers to implement bending and stretching movements by a first motor through structural designs of a prosthetic hand body, a finger transmission module, an inter-finger transmission module, and a thumb driving module, and limits the transmission torque between the motor and screws using a damping shaft and in cooperation with the telescopic characteristic of a telescopic component. On the one hand, mechanical damage to the prosthetic hand structure due to excessive torque outputted by the motor can be prevented. On the other hand, the self-adaptive grasping function of the prosthetic hand can be implemented. The disclosure can also effectively solve issues such as excessive volume or mass of the prosthetic hand, complicated control system, and low operation precision.

Abstract: The present invention provides a novel heat exchange medium to replace lead. A carbon-steel wire 1A heated in a heating furnace 11 is passed through a bath 12A filled with a liquid-phase Mg—Al—Ca alloy 20 obtained by melting a Mg—Al—Ca alloy in which the main constituent elements are Mg (magnesium), Al (aluminum) and Ca (calcium). When it passes through the bath 12A, the carbon-steel wire 1A, which has been heated for example to about 950° C. in the heating furnace 11, is cooled to about 550° C. The Mg—Al—Ca alloy is non-toxic and has no environmental impact as well.

Abstract: The present disclosure relates a method of treating chondrosarcoma or suppressing metastasis or recurrence thereof by regulating HIF-2?. The present method can be effectively used for treating chondrosarcoma or suppressing metastasis or recurrence thereof by inhibiting HIF-2? during the development and metastasis of chondrosarcoma, particularly dedifferentiated chondrosarcoma.

Abstract: The invention relates to compositions of nicotinoyl ribosides and nicotinamide riboside derivatives and their methods of use. In some embodiments, the invention relates to methods of making nicotinoyl ribosides. In some embodiments, the invention relates to pharmaceutical compositions and nutritional supplements containing a nicotinoyl riboside. In further embodiments, the invention relates to methods of using nicotinoyl ribosides and nicotinamide riboside derivatives that promote the increase of intracellular levels of nicotinamide adenine dinucleotide (NAD+) in cells and tissues for improving cell and tissue survival.

Abstract: A method for the delivery of power to subthreshold (sub-Vt) circuits uses unused current during idle-mode operation of super-threshold (super-Vt) circuits is used to supply sub-Vt circuits. Algorithmic and circuit techniques use dynamic management of idle cores when reusing the leakage current of the idle cores. A scheduling algorithm, longest idle time-leakage reuse (LIT-LR) enables energy efficient reuse of leakage current, which generates a supply voltage of 340 mV with less than ±3% variation across the tt, ff, and ss process corners. The LIT-LR algorithm reduces the energy consumption of the switch and the peak power consumption by, respectively, 25% and 7.4% as compared to random assignment of idle cores for leakage reuse. Second, a usage ranking based algorithm, longest idle time-simultaneous leakage reuse and power gating (LIT-LRPG) enables simultaneous implementation of power gating (PG) and leakage reuse in a multiprocessor system-on-chip (MPSoC) platform.

Abstract: The present invention relates to the use of the recombinant antibacterial protein Ablysin for effectively killing multidrug-resistant pathogenic bacteria. The recombinant protein Ablysin of the present invention exhibits apoptosis against antibiotic-resistant Acinetobacter baumannii, Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Enterococcus faecium to prevent or treat infectious diseases caused by these bacteria and thus it can be widely used in antibiotics, disinfectants, food additives, feed additives, and the like. In particular, the Ablysin uses peptidoglycan, which is a component of the cell wall of bacteria, as a substrate, and exhibits bacterial killing ability due to peptidoglycan degradation.

Abstract: A highly thixotropic 3D printing concrete and a manufacturing method therefor are provided. The weight percentage of each component calculated per cube of concrete is: 35-40% of cement, 0.1-0.4% of polycarboxylate superplasticizer, 0.1-0.4% of polypropylene fiber, 1.0-3.0% of special thixotropic agent for 3D printing concrete, and 12.5-14.5% of water, and the remainder is sand.

Abstract: A defrost or thaw measuring device has a dumbbell or hourglass-shaped rotatable compartment with a cavity, the cavity being partly filled with at least two phase change materials having different melting points. The measuring device may determine the time period of thawing at two or more temperature intervals in the refrigeration space.

Abstract: An optical tweezer phonon laser system and method for modulating mechanical vibrations of an optically levitated mechanical oscillator to produce coherence is disclosed. A feedback loop is configured to simultaneously supply an electro-optic modulator with an amplification signal and a cooling signal representing an amplification force linear in the mechanical oscillator momentum and a cooling force nonlinear in the mechanical oscillator variable position and linear in the momentum, respectively controlling the intensity of a trap beam levitating the mechanical oscillator.

Abstract: Wirelessly powered dielectric sensor in accordance with embodiments of the invention are disclosed. In many embodiments, a wirelessly powered dielectric sensor includes an RF-power receiving antenna that receives electromagnetic power, a power management unit (PMU) including a capacitor to rectify and store the electromagnetic power, and a dielectric constant sensing sensor, where the PMU monitors harvested energy and operates the dielectric sensing sensor; and where the dielectric sensing sensor senses a dielectric constant of a material that is in close proximity.

Abstract: A portable liquid collection device includes a liquid collector, a guide tube and a liquid collection tube. The liquid collector includes a flowing liquid hole and an anti-slip structure. The guide tube includes two ends, one end connects to the liquid collector, and the other end is in a needle-shaped structure and connects to the liquid collection tube. A gas channel and a liquid channel are disposed in a tube body of the guide tube. The guide tube is provided with an outer annular structure. The liquid collection tube includes a collection tube body and a collection tube cover. The collection tube cover includes a tube cover body and a blocking plug. A placing slot for placing the blocking plug is disposed between the top and the bottom of the tube cover body.

Abstract: The present disclosure provides a system and method for using widely available ultrasound imaging to overcome the limitations of imaging guidewires and other small objects that may be subwavelength in size relative to an ultrasound wavelength. The system and method can reduce the use of X-rays and exposure to the dangerous effects of radiation and avoids the expense of MRI technology. The subwavelength object, such as a guidewire, can be detected using several methods and associated systems described herein, including the object changing positions at a frequency that creates a brighter ultrasound image of the object as the object progresses across a scanned region of the ultrasound detector. In some embodiments, the movement of the small object causes a different speckle signature than the object itself would otherwise generate. Analysis of changes in speckle patterns due to progressive movement of an object can yield a detectable object.

Abstract: Specific parameter sets are provided that makes the transcranial focused ultrasound to selectively activate a certain neuronal type at cortical brain and enables the transcranial focused ultrasound to non-invasively induce long-term effects at deep brain. A type of ultrasound collimator with incidence angle control is designed and validated through acoustic field pressure mapping in order to target brain areas at different depths. Multi-elements transducer arrays are also used to achieve transmission of focused ultrasound.

Abstract: The present invention relates to a fault-tolerant modular permanent magnet assisted synchronous reluctance motor (PMaSynRM) and provides a modular winding connection method. The modular winding connection is to change the positions of inlet and outlet coils based on the slot electrical potential star vectogram. Then, each module has a separate set of winding and the left and right relative distribution will be adopted on the winding connection. The invention has the advantages of modularization in structure, high independence between the modules, effectively avoiding overlapping of magnetic lines between the modules, and improving fault tolerance and reliability of the motor. The invention has the advantages of modularization in structure, high independence between the modules, magnetic decoupling between the modules, and improvement of fault tolerance and reliability of the motor.

Abstract: To reduce cost for the method for separating semiconducting carbon nanotube from a mixture of metallic and semiconducting carbon nanotubes. The separation method includes preparing a dispersion by mixing a first substance, a second substance, SDS, SC, and a mixture of metallic and semiconducting carbon nanotubes with a solvent, wherein the dispersion into two layers, which are a first layer mainly containing the first substance and a second layer mainly containing the second substance, whereby the semiconducting carbon nanotube is transferred into the first layer, and the metallic carbon nanotube is transferred into the second layer, wherein the first substance is an ?-glucan which is composed of glucose linked via ?-glucosidic linkage and which has a weight average molecular weight Mw of 4,000 to 7,000 and has a ratio in amount of ?-1, 6 linked glucose residues to the entire glucose residues of 40 to 70%.

Abstract: A method of mapping transverse relaxation in a magnetic resonance (MR) scan data, comprises receiving a multi-echo spin-echo MR scan protocol comprising a plurality of MR imaging parameters, and for each echo of the multi-echo spin-echo MR scan protocol: generating, based on the parameters, a simulated echo modulation curve using a set of refocusing coherence pathways, for each of a plurality of predetermined transverse relaxation times; calculating, for each transverse relaxation time, diffusion attenuation based on a respective subset of the refocusing coherence pathways; and correcting the echo modulation curve using the diffusion attenuation. The method can also comprise comparing the scan data to the corrected echo modulation curve for each of at least a portion of the transverse relaxation values, and generating a displayed output comprising a map of transverse relaxation based on the comparison.

Abstract: A device and method are disclosed for intravenous cannulation. The device employs a spring to precisely and accurately control the force and velocity imparted to a piercing needle, with mechanical constraints built into the device to precisely and accurately control the distance through which the piercing needle travels. A sheathed-needle configuration is used with an outer, echogenic needle that can be seen via ultrasound; and an inner needle used to pierce the vein. The operator releases the piercing needle with a controlled velocity, controlled force, and controlled travel distance. The device reduces the human error and complications that have previously been associated with manually piercing a vein for cannulation.

Abstract: An eyedrop composition, and methods of making and using the same, may include one or more hydrogel forming polymer having an intrinsic viscosity [?] of at least 3 dL/g in the composition, wherein a concentration CT of such hydrogel forming polymer in the composition is at most about 5 mg/mL.