Abstract: A phosphole compound represented by the formula (wherein Ar1 and Ar2 are the same or different, and represent an optionally substituted aromatic hydrocarbon ring or an optionally substituted heteroaromatic ring; Ar3 represents a divalent ?-conjugated unit; R1 represents an optionally substituted alkyl group, an optionally substituted cycloalkyl group, an optionally substituted aryl group, or an optionally substituted heteroaryl group; R2 and R3 are the same or different, and represent a hydrogen atom, an optionally substituted alkyl group, an optionally substituted cycloalkyl group, an optionally substituted aryl group, or an optionally substituted heteroaryl group; and Z represents a reactive group) can provide a fluorescent dye capable of maintaining a high fluorescence quantum yield irrespective of solvent polarity, and providing an improved fluorescence quantum yield and light resistance even in environments containing large amounts of water.

Abstract: The present invention provides homing peptides that localize in central nervous system tissue characterized by neuroinflammation and methods of using the same.

Abstract: Techniques and apparatus for parameter error detection in a power system based on state estimation are described. In one embodiment, for example, an efficient process may be used to derive and compute only the necessary subset of the gain matrix and covariance matrix, thus avoiding the computation and storage of large dense matrices. The described efficient process can be applied either to single-scan or multiple-scan schemes. Other embodiments are described.

Abstract: Technologies for quantum sensing are disclosed. In the illustrative embodiment, a sensor system may be operated by coupling an electromagnetic wave from a measurement line to a first resonator. The sensor system includes a second resonator that is non-reciprocally coupled to the first resonator. In the absence or a perturbation, there is no reciprocal coupling between the first resonator and the second resonator, but a perturbation may cause reciprocal coupling between the first and second resonator. With appropriate selection of the non-reciprocal coupling, the signal at the output of the measurement line may allow for fast determination of whether the perturbation is present.

Abstract: Provided are an anion exchange resin being capable of producing an electrolyte membrane, a binder for forming an electrode catalyst layer and a battery electrode catalyst layer, which have improved electrical properties and chemical properties. For example, used is an anion exchange resin which has a hydrophobic unit being composed of bisphenol AF residues repeated via carbon-carbon bond and a hydrophilic unit being composed of hydrophilic groups repeated via carbon-carbon bond, in which the hydrophilic group is formed by connecting an anion exchange group to a fluorene backbone via a divalent saturated hydrocarbon group, and in which the hydrophobic unit and the hydrophilic unit are connected via carbon-carbon bond.

Abstract: The invention provides novel deoxybenzoin-containing polymers exhibiting branched (including hyperbranched) architectures, and related methods and uses thereof.

Abstract: A system for distinguishing between a human voice generated command and an electronic speaker generated command is provided. An exemplary system comprises a microphone array for receiving an audio signal collection, preprocessing circuitry configured for converting the audio signal collection into processed recorded audio signals, energy balance metric determination circuitry configured for calculating a final energy balance metric based on the processed recorded audio signals, and energy balance metric evaluation circuitry for outputting a command originator signal based at least in part on the final energy balance metric.

Abstract: The smart multiband antenna system is used in a communications system having an array of multiple identical antennas configured to operate as a single multiband antenna, such as a phased array. A tunable or variable capacitor, such as a varactor, is integrated between each adjacent pair of antennas in the array to adjust the electrical length or spacing between the antennas in order to optimize antenna performance characteristics, such as beam steering. For a phased array, the tunable capacitor may be adjusted to maintain an antenna spacing of ?/2 between adjacent antennas. The multiband antenna is designed to operate on several bands, and may be used for efficient multiplexing.

Abstract: Disclosed are peptides comprising an amphiphilic backbone and a cationic heparin-binding motif peptide. The peptides can be used in methods of antimicrobial treatment.

Abstract: A malleable bone graft composition is described. The composition comprises: (a) keratose; (b) particulate filler; (c) antibiotic; and (d) water. The invention may be provided in sterile form in an container, and optionally lyophilized. Methods of treating a fracture with such compositions are also described.

Abstract: Described herein are diagnostic and control fusion protein reagents and methods for use thereof in simple rapid and inexpensive hemagglutinin assays for the detection of subject antibodies directed to the SARS-CoV-2 virus.

Abstract: A system for assaying forces applied by cells includes an optically transparent substrate comprising a soft material having a Young's modulus within the range of about 3 kPa to about 100 kPa. An array of molecular patterns is disposed on a surface of the optically transparent substrate, the molecular patterns include fluorophore-conjugated patterns adherent to cells. The system includes at least one light source configured to excite the fluorophore-conjugated patterns and an imaging device configured to capture fluorescent light emitted from the fluorophore-conjugated patterns. Dimensional changes in the size of the patterns are used to determine contractile forces imparted by cells located on the patterns.

Abstract: The present invention provides methods and compositions for the stimulation of immune responses. In particular, the invention provides methods and compositions for enhancing an immune response to one or more antigens. Compositions and methods of the invention are useful for the treatment and/or prevention of microbial infections, such as infections caused by bacteria, viruses, fungi and parasites, as well as the treatment and/or prevention of cancer and malignant diseases. Compositions and methods of the invention include one or more antigens/immunogens together with an adjuvant formulation comprising an emulsion delivery system in combination with one or more immunostimulatory compounds (e.g., a compound that stimulates the innate immune system (e.g., a toll-like receptor antagonist (e.g., synthetic oligodeoxynucleotides (ODN)))) that enhance immune responses to the one or more antigens/immunogens when administered to a subject.

Abstract: Provided are RNA inhibitory molecules, particularly siRNA molecules silencing the expression of Voltage-Dependent Ion Chanel-1 (VDAC1) for the induction of cancer stem cell differentiation and reduction of TAMs abundance and tumor angiogenesis, thereby preventing tumor invention and recurrence.

Abstract: The disclosure relates to a complexed iodine-based electrolyte, a redox flow battery comprising the complexed iodine-based electrolyte, and a method for producing the redox flow battery.

Abstract: The present invention relates to a method for concentrating a biological sample containing nucleic acids by using magnetic chitosan microparticles and subsequently performing a PCR reaction on the nucleic acids captured on the microparticles. The chitosan microparticles added to the biological sample at a PCR compatible pH are mechanically agitated to provide for cell lysis and simultaneous DNA capture, and then serve as a solid support for the nucleic acid template during the PCR reaction. As the chitosan microparticles are utilized for lysis and the nucleic acids do not need to be removed from the microparticles before PCR, the ease of the sample preparation procedure is dramatically improved.

Abstract: A microdevice containing a plurality of nanowires on a biocompatible surface, and methods of making and using the same are provided. Aspects of the present disclosure include forming a plurality of microdevices on a substrate where each microdevice includes a plurality of nanowires. The nanowires may be loaded with an active agent by disposing the active agent onto the surface of the nanowires. Also provided herein are kits that include the subject microdevices.

Abstract: A low-temperature high-performance thermoelectric material possesses a chemical formula of (AgyCu2?y)1?xTe1?zSez, wherein ?0.025?x?0.075, 0.6?y?1.4, 0<z?0.25, diffraction peaks of a main phase of the thermoelectric material are indexed as a cubic structure at room temperature of 300 K, a highest ZT value between 300 K and 673 K is in range of 0.4 to 1.6, an average ZT value (ZT)avg is in range of 0.2 to 1.4. The highest ZT value of this material at the room temperature is comparable to that of Bi2Te3, which is an excellent complement to existing low-temperature thermoelectric materials. At the same time, the present invention also indicates a new strategy to improve the low-temperature thermoelectric performance of Cu2X-based (here, X is S, Se, Te) materials, and lays a foundation for the application of Cu2X-based materials in the field of low-temperature thermoelectricity.

Abstract: Disclosed herein, in certain embodiments, are composite materials, methods, tools and abrasive materials comprising a tungsten-based metal composition, a tungsten carbide, and an alloy. In some cases, the composite materials or matrix are resistant to oxidation.

Abstract: The present disclosure relates to evaluating an ovaling mode in a cylindrical object and determining a quality of the cylindrical object by analysis of the ovaling mode. In an embodiment, the present disclosure relates to a method for determining a structural quality of a cylindrical element, comprising measuring, as a result of a single applied force, surface vibrations of the cylindrical element via four or more surface transducers arranged on the cylindrical element along a circumference of the cylindrical element, the four or more surface transducers being equally spaced along the circumference, processing digital signals corresponding to each of the four or more surface transducers in order to generate a composite digital signal, transforming the composite digital signal to a frequency domain, comparing the transformed composite digital signal to a reference composite digital signal, and determining, based on the comparing, the structural quality of the cylindrical element.