Abstract: The invention relates to an improved process for forming a stabilised precursor that is suitable for the manufacture of carbon materials, such as carbon fibre. The process can convert a precursor comprising polyacrylonitrile into a stabilised precursor with greater efficiency. The invention also relates to a process for preparing a carbon fibre that utilises the stabilised precursor.
Type:
Grant
Filed:
December 1, 2023
Date of Patent:
December 31, 2024
Assignee:
Deakin University
Inventors:
Stephen Paul Atkiss, Maxime Robert Maghe
Abstract: The presently disclosed subject matter provides native extracellular matrix-derived membrane inserts for organs-on-chips, multilayer microfluidics microdevices, bioreactors, tissue culture inserts, and two-dimensional and three-dimensional cell culture systems. A microfluidic cell culture is provided that can include at least one membrane including extracellular matrix (ECM) material. The ECM material can be used to construct a perfusable microfluidic system including a plurality of layers of microfabricated cell culture chambers. The microfluidic cell culture can further include a lower layer including a microchannel on which the at least one membrane is placed and an upper layer including another microchannel. The upper layer can be bonded to the lower layer.
Type:
Grant
Filed:
February 11, 2020
Date of Patent:
December 31, 2024
Assignee:
The Trustees of the University of Pennsylvania
Inventors:
Dongeun Huh, Mark Mondrinos, Alex Yoon Yi, Jeongyun Seo
Abstract: A method for processing a salt solution together with carbon dioxide is disclosed. The method comprises: extracting lignin from biomass; and treating the salt solution with the lignin residue and the carbon dioxide.
Abstract: The technology described herein is directed to inducible and repressible polypeptides and polypeptide systems. In particular, described herein are split sequence-specific nucleases and split recombinases that are linked to drug-inducible or drug-repressible dimerization domains. In some embodiments, the polypeptides comprise sequestering domains and/or have their expression controlled by an inducible promoter. In multiple aspects described herein are polynucleotides, vectors, cells, and pharmaceutical compositions comprising said polypeptides or polypeptide systems. Also described herein are methods of using said polypeptide systems to modulate the expression of a target polypeptide or to treat a subject in need of a cell therapy.
Abstract: A method for producing crystalline ?-Fe2O3 nanoparticles involving ultrasonic treatment of a solution of an iron (III)-containing precursor and an extract from the seeds of a plant in the family Linaceae. The method involves preparing an aqueous extract from the seeds of a plant in the family Linacae and dropwise addition of the extract to the solution of an iron (III)-containing precursor. The method yields crystalline nanoparticles of ?-Fe2O3 having a spherical morphology with a diameter of 100 nm to 300 nm, a mean surface area of 240 to 250 m2/g, and a type-II nitrogen adsorption-desorption BET isotherm with a H3 hysteresis loop. A method for the photocatalytic decomposition of organic pollutants using the nanoparticles is disclosed. An antibacterial composition containing the crystalline ?-Fe2O3 nanoparticles is also disclosed.
Abstract: A surgical system is provided. The surgical system includes a camera operable to capture images and/or video. A projector is operable to project light, and a controller is communicatively coupled with the camera and the projector. The controller is operable to track movement of bone in real-time during surgery based on the images and/or video captured by the camera, and control the projector to project the light including a cutting line on the bone to indicate a cutting plane for cutting the bone during surgery.
Type:
Grant
Filed:
March 8, 2023
Date of Patent:
December 31, 2024
Assignees:
Navisect, Inc., The Research Foundation for The State University of New York_
Inventors:
Fazel Khan, Michael Bielski, Jafar Khan, Imin Kao, Guangyu He
Abstract: Subway tunnel intelligent monitoring method and system relate to the field of track detection. The method includes: activating the inspection device to inspect the track section and detect foreign objects; when the inspection device detects the foreign object during foreign object detection, identifying and acquiring a volume of the foreign object, and according to a correspondence between a range interval to which the volume of the foreign object belongs and a processing scheme, determining the processing scheme for the foreign object with the corresponding volume; implementing the processing scheme for the foreign object with the corresponding volume.
Type:
Grant
Filed:
July 3, 2024
Date of Patent:
December 31, 2024
Assignee:
Shenzhen University
Inventors:
Xiangsheng Chen, Xiaohua Bao, Hongzhi Cui, Jun Shen
Abstract: Isolated or recombinant EphA5 or GRP78 targeting antibodies are provided. In some cases, antibodies of the embodiments can be used for the detection, diagnosis and/or therapeutic treatment of human diseases, such as cancer. A method of rapidly identifying antibodies or antibody fragments for the treatment of cancer using a combination of in vitro and in vivo methodologies is also provided.
Type:
Grant
Filed:
June 10, 2022
Date of Patent:
December 31, 2024
Assignee:
Rutgers, The State University of New Jersey
Inventors:
Renata Pasqualini, Wadih Arap, Fernanda Iamassaki Staquicini, Fortunato Ferrara, Sara D'Angelo, Andrew R. M. Bradbury
Abstract: The present application discloses a testing device and a testing method for multiple piston assembly of a cam-lobe hydraulic motor. N cylinder blocks are installed on the cylinder block base, and piston assemblies to be tested are installed on the cylinder blocks. A driving plate is installed on the cylinder block base, and N uniformly-distributed driving plate clamping grooves are formed in the driving plate. A cylinder block protrusion is arranged at the bottom of each cylinder block, and the cylinder block protrusions are clamped in the driving plate clamping grooves. When the driving plate is rotated, the N driving plate clamping grooves drive the N cylinder blocks to rotate synchronously through the cylinder block protrusions, to synchronously change the pressure angle between a driving shaft and each piston assembly.
Abstract: A method includes: sending a pause frame followed by a migrate frame when a value of one of per-flow buffer usage (FBU) counters (referred to as a counter value) exceeds a pause threshold; stopping dequeuing one of pause egress queues (PEQs) when receiving a pause frame; enqueuing a packet into one of the PEQs when receiving a migrate frame; sending a resume frame followed by a migrate-back frame when a previous counter value exceeds the pause threshold and a current counter value is smaller than a resume threshold; when receiving a resume frame, resuming dequeuing one of the PEQs until empty, and then dequeuing a default egress queue (DEQ); and enqueuing a packet into the DEQ when receiving a migrate-back frame.
Type:
Grant
Filed:
August 31, 2022
Date of Patent:
December 31, 2024
Assignee:
National Yang Ming Chiao Tung University
Abstract: The present disclosure provides a mechanical linkage device including a ground link comprising an inverse center linked to one end of the ground link. The mechanical linkage device further includes a movement link connecting the ground link to a control point. The mechanical linkage device further includes two or more linkages having a first link of the two or more linkages including a first end linked to the control point and a second link of the two or more linkages including second end linked to an end point. The end point, the control point, and the inverse center of the ground link remain co-linear. The control point and the end point have an inverse relationship such that movement of the control point is inversely translated to the end point. The ground link, the movement link, and at least one of the two or more linkages do not all he in a plane throughout an entire range of motion of the mechanical linkage device.
Abstract: Described herein are methods of epigenetic modification of fungi and uses thereof. Also described herein are compounds that can have antileishmanial activity and formulations thereof. Also described herein are methods of treating leishmanial infection in a subject that include the step of administering a compound or formulation thereof described herein to the subject.
Type:
Grant
Filed:
August 18, 2021
Date of Patent:
December 31, 2024
Assignees:
UNIVERSITY OF SOUTH FLORIDA, INSTITUTO POLITÉCNICO NACIONAL, KING ABDULAZIZ UNIVERSITY
Inventors:
Bill J. Baker, Dennis E. Kyle, Mario Alberto Rodriguez-Pérez, Anne-Claire D. Limon, Ala Azhari
Abstract: Provided are a fluororesin-containing composition having significantly improved fluidity and a method for producing the same. The fluororesin-containing composition contains 99.99 to 97% by mass of a fluororesin having a melting point of 205° C. to 225° C. and 0.01 to 2% by mass of a thermotropic liquid crystal polymer. The method for producing the fluororesin-containing composition includes kneading polychlorotrifluoroethylene and a thermotropic liquid crystal polymer at 285° C. to 320° C.
Abstract: The invention provides methods and apparatus comprising a multi-wavelength laser source that uses a single unfocused pulse of a low intensity but high power laser over a large sample area to collect Raman scattered collimated light, which is then Rayleigh filtered and focused using a singlet lens into a stacked fiber bundle connected to a customized spectrograph, which separates the individual spectra from the scattered wavelengths using a hybrid diffraction grating for collection onto spectra-specific sections of an array photodetector to measure spectral intensity and thereby identify one or more compounds in the sample.
Type:
Grant
Filed:
July 13, 2022
Date of Patent:
December 31, 2024
Assignee:
UNIVERSITY OF MARYLAND BALTIMORE COUNTY
Inventors:
Bradley Arnold, Christopher Cooper, John Cataldi
Abstract: Therapeutic oligonucleotides comprising pharmacokinetic (PK)-modifying anchors are provided. Methods for treating diseases or disorders comprising administering to a subject a therapeutic oligonucleotide comprising one or more PK-modifying anchors are provided.
Type:
Grant
Filed:
April 20, 2022
Date of Patent:
December 31, 2024
Assignee:
UNIVERSITY OF MASSACHUSETTS
Inventors:
Anastasia Khvorova, Bruno Miguel da Cruz Godinho, Matthew Hassler
Abstract: A method comprising: receiving, as input, training images, wherein at least a majority of the training images represent normal data instances; receiving, as input, a target image; extracting (i) a set of feature representations from a plurality of image locations within each of the training images, and (ii) target feature representations from a plurality of target image locations within the target image; calculating, with respect to a target image location of the plurality of target image locations in the target image, a distance between (iii) the target feature representation of the target image location, and (iv) a subset from the set of feature representations comprising the k nearest the feature representations to the target feature representation; and determining that the target image location is anomalous, when the calculated distance exceeds a predetermined threshold.
Type:
Grant
Filed:
March 25, 2021
Date of Patent:
December 31, 2024
Assignee:
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
Inventors:
Yedid Hoshen, Liron Bergman, Niv Cohen, Tal Reiss
Abstract: The method of metered switching for a high-performance liquid chromatography (HPLC) sample injector is a method of controlled switching for a HPLC sample injector to control the amount of the sample being transferred to the HPLC separation column. In a load mode of the HPLC sample injector, a sample to be tested is injected therein until a sample loop is filled. The HPLC sample injector is switched into an injection mode such that a pressurized mobile phase pushes the sample through the sample loop and out of an outlet port. The HPLC sample injector is then switched back into the load mode at a selected time corresponding to a desired volume of the sample to be dispensed from the outlet port. The time-dependent correspondence between a flow rate of the pressurized mobile phase and the desired volume of the sample for the sample loop is already known.
Type:
Grant
Filed:
February 19, 2024
Date of Patent:
December 31, 2024
Assignee:
KING SAUD UNIVERSITY
Inventors:
Ahmad Aqel Ifseisi, Mohamed Ali Ouladsmane, Ahmed Yacine Badjah Hadj Ahmed, Zeid Abdullah Alothman
Abstract: There is provided an RF sputtering apparatus for controlling an atomic layer of a thin film. The RF sputtering apparatus includes: a sputtering main body including a substrate, a target facing the substrate, and a chamber for performing a sputtering process to deposit the target on the substrate; a power supply unit connected to the target of the sputtering main body via a network to apply RF power; a roughing pump unit for forming vacuum inside the chamber of the sputtering main body; and a gas supply unit for supplying reaction gas to the inside of the chamber. A power cable for supplying a power source to the power supply unit is formed with a single crystal copper wire.
Type:
Grant
Filed:
August 31, 2021
Date of Patent:
December 31, 2024
Assignee:
PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION
Inventors:
Se Young Jeong, You Sil Lee, Su Jae Kim, Sang Eon Park, Mi Yeon Cheon