Abstract: According to the present invention, there is provided a superconducting induction rotating machine 1 that has a stator for which a plurality of superconducting armature coils are placed along the circumferential direction, and a rotor provided rotatably around a central axis line in a state opposing the stator with a predetermined gap interposed, wherein the rotor is configured of a complex consisting of a cylindrical electrically conductive material layer disposed on a side opposing the stator, and a magnetic material layer disposed on an opposite side to the side opposing the stator of the electrically conductive material layer, and wherein the superconducting induction rotating machine 1 rotationally drives the rotor by generating a rotational torque in the rotor with a rotating magnetic field created by the armature coils while the superconducting armature coils disposed on the stator being cooled to a superconducting state.
Type:
Grant
Filed:
April 24, 2020
Date of Patent:
December 31, 2024
Assignees:
KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
Abstract: An improved carrier frequency offset synchronization method for the VDE-TER system includes matching and filtering the data at a receiver of the system, extracting a training sequence from an information data segment after matching and filtering; performing a carrier frequency offset estimation based on the training sequence to obtain a frequency offset estimated value; based on the frequency offset estimated value, performing a frequency offset compensation on the information data segment to obtain a first-level compensation data segment; performing a phase tracking on the first-level compensation data segment to obtain a cumulative phase compensation value, thereby obtaining a second-level compensation data segment; and demodulating the second-level compensation data segment to obtain the received information after synchronization.
Abstract: Compounds and treatment methods with compounds exhibiting antiviral activity and/or inhibition of viral replication against viruses, particularly those belonging to the picornavirus-like supercluster, including coronavirus having a formula: or a prodrug or pharmaceutically-acceptable salt thereof, where: each X comprises at least one cyclic moiety directly attached to the oxygen or connected via an alkyl linkage, where at least one of the linkage and/or the X moiety comprises a deuterium substitution; and Z is selected from the group consisting of aldehydes and bisulfite salts, or the ester or carbamate prodrugs thereof.
Type:
Grant
Filed:
June 9, 2021
Date of Patent:
December 31, 2024
Assignees:
Kansas State University Research Foundation, Wichita State University, University of Iowa Research Foundation
Inventors:
Kyeong-Ok Chang, Yunjeong Kim, William C. Groutas, Stanley Perlman
Abstract: Articles including a solid porous material having a selenium nanomaterial bound to a surface of and within the solid porous material. The article may be a include no polymeric stabilizer or proteinaceous stabilizer. The solid porous material may be a sponge, a film, a fabric, a non-woven material, or a metal-organic framework (MOF), or a combination thereof. The article may be produced by treating a solid porous material with an aqueous selenous acid solution and heating the solid porous material to form the selenium nanomaterial on the surface of and within the solid porous material.
Abstract: The present disclosure relates to an optical clearing method called lipid-preserving index matching for prolonged imaging depth (LIMPID). The optical clearing method can include simply immersing a sample in an optical clearing solution before imaging (e.g., with microscopy or optical coherence tomography). The optical clearing solution can include water; an iodine-containing non-ionic radiocontrast agent; and urea.
Type:
Grant
Filed:
November 9, 2018
Date of Patent:
December 31, 2024
Assignees:
CASE WESTERN RESERVE UNIVERSITY, UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER, VANDERBILT UNIVERSITY
Abstract: A rotor cooling structure includes a turbine blower structure provided on first and second sides of a rotor for an induction motor; a refrigerant passage including a plurality of refrigerant passage inlet openings provided on a bottom surface of the turbine blower structure and a plurality of refrigerant passage outlet openings provided at an axial center of the rotor, which fluidically communicates with the refrigerant passage inlet openings and the refrigerant passage outlet openings and is provided along conductor bars of the rotor; and a plurality of micro groove patterns that hold the refrigerant passage outlet openings and are provided on both axial sides of the rotor on an external periphery of the rotor.
Type:
Grant
Filed:
June 21, 2022
Date of Patent:
December 31, 2024
Assignees:
Hyundai Motor Company, Kia Corporation, IUCF-HYU (Industry-University Cooperation Foundation Hanyang University)
Inventors:
Jin Ho Choi, Jong Seok Lee, Sang Jin Park, Sung Woo Hwang, Jae Hyun Kim, Myung Seop Lim
Abstract: A microfluidic device having an array for cell trapping is used to analyze cell-cell interaction at single-cell level. The microfluidic trapping array efficiently pairs single cells in isolated compartments in an easy-to-operate manner. A first cell is squeezed through an opening of a first cavity by a strong forward flow. Subsequently, a second cell is pushed into a second cavity by a low reverse flow. The trapped cell pairs are sealed by an oil phase or hydrogel into isolated compartments, thereby eliminating interference from other cell pairs or the surrounding media.
Type:
Grant
Filed:
August 7, 2020
Date of Patent:
December 31, 2024
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Abstract: Provided are methods for sequential radiotherapies, such as XRT. In some embodiments, a higher dosage of an XRT may first be administered to a subject, optionally in combination with an immunotherapy, and subsequently a lower dosage XRT is administered to the subject to treat a cancer. Separating the dosage and intensity of the radiotherapies can be used to achieve improved therapeutic responses, such as improved anti-cancer responses, survival times, and/or abscopal effects.
Type:
Grant
Filed:
December 9, 2019
Date of Patent:
December 31, 2024
Assignee:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Inventors:
James Welsh, Maria Angelica Cortez, David Hong, Hampartsoum Berj Barsoumian
Abstract: This discloses that compounds of Formula 1 have antifibrotic properties. In particular, this discloses a pharmaceutical composition including one or more compounds of Formula 1 and methods of using compounds of Formula 1 in fibrosis treatment and inhibiting type 1 collagen synthesis.
Type:
Grant
Filed:
November 22, 2022
Date of Patent:
December 31, 2024
Assignees:
Florida State University Research Foundation, Inc., The Florida International University Board of Trustees
Abstract: A method for slope geological disaster treatment and mineral resource recovery includes the following steps: S1: dividing a mountain top into a plurality of treatment sections and treatment segments; S2, selecting an easy-to-slide area at the upper portion of a first treatment segment and blasting an easy-to-slide body to make the easy-to-slide body roll down to a bottom of the slope; S3, forming a regular initial slope bench; S4, mining coal at the coal seam in a grouped mining adit manner, and laying grouting pipelines in the primary mining adits; S5, forming closed mining adits; S6, excavating secondary mining adits at intervals of the primary mining adits in sequence; S7, continuing mining in an adjacent second treatment segment in the same manner; and S8, continuing mining the first treatment segment of the second treatment section in the same manner.
Type:
Grant
Filed:
July 26, 2022
Date of Patent:
December 31, 2024
Assignee:
CHINA UNIVERSITY OF MINING AND TECHNOLOGY
Inventors:
Shuzhao Chen, Liu Han, Cangyan Xiao, Meng Yang
Abstract: A vibration-driven energy harvesting device includes a vibration-driven energy harvesting element that generates power according to vibrations of an electrode; an output unit that, when connected to a load resistor, extracts power generated by the vibration-driven energy harvesting element; a judgment unit that judges whether or not a power value of the power is greater than a predetermined threshold value; a determination unit that determines an input impedance of the output unit based on a judgment result obtained by the judgment unit; and an adjustment unit that adjusts the input impedance of the output unit according to a determination made by the determination unit.
Type:
Grant
Filed:
December 17, 2021
Date of Patent:
December 31, 2024
Assignees:
Saginomiya Seisakusho, Inc., Keio University
Inventors:
Hiroyuki Mitsuya, Hisayuki Ashizawa, Song-Ju Kim, Masashi Aono
Abstract: A method for preparing a weathered coal-derived humic acid/urea-formaldehyde slow-release fertilizer granule by reactive extrusion process with depolymerization-activation-polycondensation trinity is provided. In an alkaline environment, paraformaldehyde is depolymerized into formaldehyde small molecules, which react with urea to form monohydroxymethylurea and dihydroxymethylurea. Under the strong shearing action of screws of the twin-screw reactive extruder, the macromolecular weathered coal-derived humic acid is depolymerized into relatively small molecule weathered coal-derived humic acid, and abundant active carboxyl groups are exposed, some of which immediately undergo dehydration condensation with —NH2 on the urea-formaldehyde molecule produced by the polycondensation of hydroxymethylurea during the reactive extrusion process to generate weathered coal-derived humic acid/urea-formaldehyde and its granules.
Type:
Grant
Filed:
February 3, 2024
Date of Patent:
December 31, 2024
Assignees:
NORTH UNIVERSITY OF CHINA, SHANXI ZHONGBEI NEW MATERIAL TECHNOLOGY CO., LTD.
Abstract: It is an object of an aspect of the present invention to provide (i) transformants, whose proliferation depends on phosphite, of various species of organism and (ii) a method for detecting the presence of a reduced phosphorous compound with use of such a transformant. Use is made of a transformant which is defective in functions of a gene encoding a phosphate transporter protein and a gene encoding a phosphate ester transporter protein and into which a gene encoding a hypophosphite transporter protein is introduced, a signal peptide of a hypophosphite binding protein being substituted with a signal peptide derived from a host or a species of organism closely related to the host.
Abstract: The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms.
Type:
Grant
Filed:
June 15, 2021
Date of Patent:
December 31, 2024
Assignees:
The Regents of the University of California, University of Vienna
Inventors:
Jennifer A. Doudna, Martin Jinek, Krzysztof Chylinski, Emmanuelle Charpentier
Abstract: Methods of fabricating 3D printed structures from biocompatible proteins include forming a photoreactive, proteinaceous resin, and 3D printing biocompatible structures from the resin by the patterned application of light in a select wavelength to cure the resin into the desired structures. Suitable photoreactive proteinaceous resins can be formed by reacting an aqueous solution of an acrylated or methacrylated globular protein with a photoreactive comonomer or photoinitiator. Structures printed from the photoreactive, proteinaceous resin can be photo-cured and dried to form bioplastic structures.
Type:
Grant
Filed:
June 16, 2020
Date of Patent:
December 31, 2024
Assignee:
University of Washington
Inventors:
Alshakim Nelson, Siyami Millik, Ryan Thomas Shafranek, Patrick Smith
Abstract: A charge detection mass spectrometer (CDMS) includes an electrostatic linear ion trap (ELIT), a processor, and a memory having instructions stored therein executable by the processor to (a) control the ELIT to trap an ion, (b) collect ion measurement information as the trapped ion oscillates back and forth through the ELIT, the ion measurement information including charge induced by the ion on a charge detector of the ELIT during each pass of the ion through the ELIT and timing of the induced charges relative to one another, (c) process the ion measurement information in the time-domain for each of a plurality of sequential time windows of the ion measurement information to determine a charge magnitude of the ion during each time window, and (d) determine the magnitude of charge of the trapped ion based on the charge magnitudes of each of the time windows.
Abstract: An improved modal decomposition method applicable to the analysis and reconstruction of the measured flow fields of internal solitary waves includes the following steps: S1. generating internal solitary waves and measuring a two-dimensional flow field sequence during the interaction of the internal solitary waves with the terrain; S2. extracting a target information from the two-dimensional flow field sequence and obtaining a flow field snapshot; S3. stitching the snapshots into a snapshot matrix in time order; S4. plotting the information density curve; S5. normalizing the information density curve and determining split points; S6. setting the snapshot matrix between two adjacent split points as a linear evolutionary characteristic stage; and S7. performing dynamic mode decomposition on the linear evolutionary characteristic stages.
Abstract: A piezoelectric transducer is provided herein, comprising a three-dimensional structure made of a plurality of peptides, the peptides being self-assembling and the structure being piezoelectric, wherein at least a portion, or each, of said plurality of peptides comprises peptides of 2 to 10 amino acid residues, provided that the plurality of peptides is not consisted of a plurality of Phe-Phe dipeptides. Further described herein are peptides having an amino acid sequence Hyp-Phe-Phe, Boc-Dip-Dip, (L)Trp-(D)Trp or (D)Trp-(L)Trp, as well as three-dimensional structures comprising such peptides.
Type:
Grant
Filed:
March 25, 2020
Date of Patent:
December 31, 2024
Assignees:
Ramot at Tel-Aviv University Ltd., Xidian University
Inventors:
Ehud Gazit, Santu Bera, Yu Chen, Sharon Gilead, Kai Tao, Sigal Lazar, Rusen Yang, Sudipta Mondal, Vasantha Basavalingappa
Abstract: A two-dimensional photonic-crystal surface-emitting laser includes an active layer, a two-dimensional photonic crystal, and electrodes. The two-dimensional photonic crystal contains a plate-shaped base material arranged on one side of the active layer and different refractive index portions arranged at lattice points of a predetermined lattice in the base material and having a refractive index different from that of the base material, a band edge frequency for each position in an electric current supply region, which is at least a part of the two-dimensional photonic crystal, is monotonically increased in one direction parallel to the base material. Such a two-dimensional photonic crystal occurs when the different refractive index portion has a refractive index smaller than that of the base material, a filling factor, which is a ratio of a volume occupied by the different refractive index portion in a unit lattice constituting the lattice, is monotonically increased in the one direction.
Type:
Grant
Filed:
August 4, 2020
Date of Patent:
December 31, 2024
Assignee:
KYOTO UNIVERSITY
Inventors:
Susumu Noda, Takuya Inoue, Masahiro Yoshida, Menaka De Zoysa