Patents Assigned to TNO
  • Plant growing material
    Publication number: 20060185237
    Abstract: A growing material for plants comprising a coherent substrate material for including and therein roots of a plant to be supported by the substrate material, wherein in the substrate, locally, provisions (4) have been embedded which are manufactured from a material impenetrable by roots and are, at least partly, surrounded by material penetrable by roots, thereby forming, locally, embedded, in the substrate for the roots, a layer in the form of a porous net-shaped or sieve-shaped barrier so that during growing the roots are forced to deflect and bend through the porous net-shaped or sieve-shaped barrier, thereby spreading over the substrate material in an optimal manner and growing roots therein more intensively.
    Type: Application
    Filed: March 5, 2004
    Publication date: August 24, 2006
    Applicant: Netherlandse Organisatie voor toegepast- natuurweten schappelijk Onderzoek TNO
    Inventors: Rene van der Meulen, Davy de Witt, Albert van Duijn
  • Detection of demyelination
    Publication number: 20060166270
    Abstract: The present invention relates to a method for the detection of demyelinization in a mammal, comprising providing an NMR spectrum of metabolites in a body fluid of an individual of said mammal in which demyelinization is suspected and comparing said NMR spectrum with a difference profile, comprising a plurality of NMR spectral line positions, which express the normalized difference between one or more NMR spectra of metabolites in a body fluid of one or more healthy individuals of said mammal, and one or more corresponding NMR spectra of metabolites in a corresponding body fluid of one or more individuals of said mammal in which demyelinization has been diagnosed. The invention further relates to the said difference profile for the detection of demyelinization in a mammal and to methods for the manufacture thereof.
    Type: Application
    Filed: November 10, 2003
    Publication date: July 27, 2006
    Applicant: NEDERLANDSE ORGANISATIE voortoegepastnatuurweten schappelijk ONDERZOEK TNO
    Inventors: Jacobus Vogels, Lybert 'T Hart
  • Reinforced filter material
    Patent number: 7071247
    Abstract: The invention relates to a porous mold for use in a pressure casting process, which mold is manufactured of a polymeric material forming a matrix into which a clay and a block copolymer or a graft copolymer have been incorporated, wherein the block copolymer or graft copolymer comprises one or more first structural units (A), which are compatible with the clay, and one or more second structural units (B), which are compatible with the polymeric matrix. The invention further relates to a process for producing said mold and to the use of said mold in a pressure casting process.
    Type: Grant
    Filed: July 2, 2001
    Date of Patent: July 4, 2006
    Assignee: Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek TNO
    Inventors: Hartmut Rudolf Fischer, Lawrence Fabian Batenburg, Leonardus Johannus Maria Dortmans
  • Modification of collagenous materials and medical treatment, diagnosis and monitoring of fibrotic conditions
    Publication number: 20060141568
    Abstract: The present invention relates to the gene PLOD2 which codes for telopeptide lysyl hydroxylase (TLH). This enzyme converts telopeptidyl Lys into telopeptidyl Hyl, that can subsequently be converted into hydroxyallysine cross-links. Collagen with hydroxyallysine cross-links shows a higher resistance to degradation by proteinases than collagen with cross-links derived from allysine. In one aspect, the invention provides methods and compositions to prepare collagenous materials with varying biodegradation rates by varying the ratio of hydroxyallysine cross-links over allysine cross-links. In another aspect, the invention provides methods and compositions to lower the ratio of hydroxyallysine cross-links over allysine cross-links in fibrotic processes, in order to obtain a collagenous network that is more easy to degrade.
    Type: Application
    Filed: October 11, 2005
    Publication date: June 29, 2006
    Applicant: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO
    Inventors: Rudolf Bank, Annemarie van der Slot, Anne-Marie Zuurmond, Johannes te Koppele
  • Method and apparatus for determining a phase transition of a substance
    Publication number: 20060140247
    Abstract: A method for determining a phase transition of a substance, comprising: generating a first measuring signal by measuring a substance-directed heat flow; generating a phase-shifted measuring signal which is phase-shifted in relation to the first measuring signal; determining a difference signal between the first measuring signal and the phase-shifted measuring signal and determining the phase transition if a property of the difference signal meets a predetermined condition.
    Type: Application
    Filed: September 4, 2003
    Publication date: June 29, 2006
    Applicant: Nederlandse Organisatie voor toegepastnatuurwetens chappelijk Onderzoek TNO
    Inventor: Huib Blokland
  • Light emitting diode
    Publication number: 20060138447
    Abstract: The invention relates to a light emitting diode having at least one (semi)conductive electroluminescent active layer which comprises at least two different electroluminescent functionalities, wherein the emission spectrum of the diode exhibits at least two intensity maxima. The invention further relates to a detector which comprises a light emitting diode which is capable of emitting light at least two mutually separate intensity maxima.
    Type: Application
    Filed: June 17, 2004
    Publication date: June 29, 2006
    Applicant: Nederlandse organisatie voor toegepast- natuurwetenschappelijk Onderzoek TNO
    Inventors: Harmannus Schoo, Hermanus Hendricus Bekman, Jacobus Van Veen
  • Measuring wavelength change
    Patent number: 7061609
    Abstract: An optical wavelength analyser including: an entrance slit (4) for receiving a light beam (3) including signals with various wavelengths and passing the beam at least partly; a diffractor (6, 7, 9) for receiving the passed beam and diffracting the signals dependent on their wavelength; a detector (8) including adjacent detector elements (32, 33, 35, 36, 38, 39) for receiving the diffracted signals and generating their output signals; a processor (21) for determining the wavelengths from the output signals, in which the received light beam has a spatially uniform intensity; the diffractor diffracts each signal on a different detector element subset, consisting of at least a first element (32, 33, 35, 36, 38, 39.) for receiving at least a first signal with a first signal level; the processor determines each signal's wavelength dependent on the first signal level and a calibration value.
    Type: Grant
    Filed: May 1, 2001
    Date of Patent: June 13, 2006
    Assignee: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO
    Inventor: Lun Kai Cheng
  • Method for absorption of acid gases
    Publication number: 20060117954
    Abstract: The invention relates to a method for the absorption of acid gases, such as CO2 and H2S, from gas mixtures. According to the invention, acid gases are absorbed from a gas mixture by contacting this gas mixture with a liquid in which is dissolved so high a concentration of an amino acid or a salt thereof that a precipitate is formed. The contact takes place in a column of the packing-free type or a column suitable for processing slurries.
    Type: Application
    Filed: May 7, 2003
    Publication date: June 8, 2006
    Applicant: NEDERLANDSE ORGANISATIE voortoegepastnatenschappel ijk ONDERZOEK TNO
    Inventors: Geert Versteeg, Paramasivam Kumar, Johannes Hogendoorn, Paul Feron
  • Method and system for identifying and quantifying chemical components of a mixture
    Patent number: 7056434
    Abstract: Method and system for processing and evaluating data from combination chromatographic and mass spectrometric data. The methods and system comprise data smoothing and determination of an quality factor for a chromatogram of a data set based on a determined entropy value. In one embodiment, the methods and system further comprise data baseline correction prior to entropy value determination. In a further embodiment, a correlation is determined between chromatograms processed according to the invention and one or more chromatograms of one or more data sets. Preferably, said correlation is performed using a multivariate analysis.
    Type: Grant
    Filed: April 22, 2004
    Date of Patent: June 6, 2006
    Assignee: Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek TNO
    Inventors: Jan van der Greef, Jacibus Thomas Wilhelmus Elisabeth Vogels, Florian Wulfert, Albert Tas
  • Process for cleaning filters
    Patent number: 7052557
    Abstract: Filters used in the food and beverage industry can be cleaned by contacting the filters with a cyclic nitroxyl compound and a reoxidator or with a nitroxonium compound in a bromine-free process. The nitroxyl can be TEMPO or its 4-acetamido or 4-acetoxy derivative, and the nitroxonium compound can be the corresponding oxidized ion obtained by enzymatic or metal catalyzed oxidation. The reoxidator may be a peracid, such as peracetic acid, persulphuric acid or permanganic acid, or a metal complex with a hydroperoxide.
    Type: Grant
    Filed: January 20, 2003
    Date of Patent: May 30, 2006
    Assignee: Nederlandse Organisatie voor Toegepast-Natuurwetenschappelijk Onderzoek (TNO)
    Inventors: Jan Matthijs Jetten, Jan Pieter Van Der Lugt, Hendrik Arend Van Doren, Mario Tarcisius Raymundus Van Wandelen
  • Prevention therapy and prognosis/monitoring in sepsis and septic shock
    Publication number: 20060111283
    Abstract: The invention relates to the use of a peptide which binds to lipopolysaccharide (LPS) or lipoteichoic acid (LTA), for manufacturing a pharmaceutical composition for treating sepsis or septic shock, wherein the peptide comprises the amino acid sequence of apolipoprotein CI (apoCI) or a part thereof that comprises at least the amino acids of the C-terminal helix of apoCI. The use of human apoCI is preferred. The peptide can be administered clinically to patients who have sepsis or threaten to develop sepsis. Measurement of the apoCI content in blood can be utilized for determining the severity and prognosis of the course of the septic condition or for monitoring an anti-sepsis treatment.
    Type: Application
    Filed: June 27, 2003
    Publication date: May 25, 2006
    Applicant: Nederlandse Oranisatie Voor Toegepastnatuurwetenschappelijk Onderzoek TNO
    Inventors: Patrick Rensen, Aloysinus Havekes
  • Modification of collagenous materials and medical treatment, diagnosis and monitoring of fibrotic conditions
    Patent number: 7045600
    Abstract: The present invention relates to the gene PLOD2 which codes for telopeptide lysyl hydroxylase (TLH). This enzyme converts telopeptidyl Lys into telopeptidyl Hyl, that can subsequently be converted into hydroxyallysine cross-links. Collagen with hydroxyallysine cross-links shows a higher resistance to degradation by proteinases than collagen with cross-links derived from allysine. In one aspect, the invention provides methods and compositions to prepare collagenous materials with varying biodegradation rates by varying the ratio of hydroxyallysine cross-links over allysine cross-links. In another aspect, the invention provides methods and compositions to lower the ratio of hydroxyallysine cross-links over allysine cross-links in fibrotic processes, in order to obtain a collagenous network that is more easy to degrade.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: May 16, 2006
    Assignee: Nederlandse Organisatie voor Toegepastnatuur-Wetenschappelijk Ondrezoek TNO
    Inventors: Rudolf Antonius Bank, Annemarie Jozefien van der Slot, Anne-Marie Zuurmond, Johannes Maria te Koppele
  • Method for displaying data
    Patent number: 7019747
    Abstract: A method is described for displaying data, wherein the data consists of a number of samples Nr that is much larger than the number of samples Ns that can be displayed on a display. According to the invention sets of Nc=Nr/Ns samples are formed and for each set Nc a single value xt is determined according to a specific algorithm by which important features as reflected by the samples, despite the reduction in samples, still can be displayed with a better SNR than with presently known methods.
    Type: Grant
    Filed: May 30, 2002
    Date of Patent: March 28, 2006
    Assignee: Nederlandse Organisatie Voor Toegepastnatuurwetenschappelijk Onderzoek Tno
    Inventor: Pascal Alfred M. de Theije
  • System for performing tests on intelligent road vehicles
    Patent number: 7013704
    Abstract: A system for carrying out research on a drivable vehicle or a component thereof, includes: a test stand on which the vehicle or the component can be positioned, which vehicle or which component is provided with at least one sensor for receiving signals from the environment of the vehicle or of the component, at least one object which is situated in the vicinity of the test stand, elements for generating a relative movement between the test stand and the at least one object, and a control computer for coordinating the relative movement between the test stand and the object.
    Type: Grant
    Filed: June 22, 2001
    Date of Patent: March 21, 2006
    Assignee: Nederlandse Organisatie Voor Toegepast—Natuurwetenschappelijk Onderzoek Tno
    Inventors: Leonardus Johannes J. Kusters, Ralph Jacques A. Kleuskens, Dirk Jan Verburg, Albertus Clemens M. van der Knaap
  • Method for drying finely divided substances
    Patent number: 6986213
    Abstract: A method for drying a granular solid, the finely divided solid to be dried being mixed with zeolite granules, after which drying takes place by removal of water from the solid. The solid dried by removal of moisture is then separated from the zeolite. According to the invention, the solid to be dried is dried in a mixer without external supply of heat, after which the dried solid is at least virtually completely separated from the zeolite granules after a residence time in the mixer. This is advantageous in particular when drying foods, such as wheat flour.
    Type: Grant
    Filed: May 23, 2001
    Date of Patent: January 17, 2006
    Assignee: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO
    Inventors: Arjen Johannes Kruithof, Pieter Jan W. Blom, Paulus Statius R. Kosters, Paulus Josephus T. Bussmann
  • Microbiological information system
    Publication number: 20060009912
    Abstract: The present invention relates to an apparatus and a method for the classification of microorganisms. In particular, the invention relates to an apparatus and method for the classification of microorganisms with annotation of clinically and/or industrially relevant information. An apparatus according to the invention comprises a measuring apparatus for classifying a microorganism according to distinctive features, a database containing clinically and/or industrially relevant information of a plurality of microorganisms, and a calculation unit for comparing the results from the measuring apparatus to the information in the database for the annotation of the clinically and/or industrially relevant information to the microorganism, and in which the measuring apparatus, the database and the data analysis apparatus are provided with input and output means.
    Type: Application
    Filed: April 24, 2003
    Publication date: January 12, 2006
    Applicant: Nederlandse Oranisatie Voor Toegepastnatuurwetenschappelijk Onderzoek TNO
    Inventors: Henricus Thijsen, Roy Montijn, Frank Schuren
  • Method for preventing the formation of spots at the surface of mushrooms and mushrooms thereby obtained
    Publication number: 20050287255
    Abstract: The invention relates to a method for preventing at least the formation of spots at the surfaces of edible mushrooms such as ordinary button mushrooms. Further, the invention relates to mushrooms with a longer time of sale. By means of the invention, it has appeared possible to prolong the period between harvesting and the formation of a substantial amount of brown spots at the surface of a number of mushrooms of good quality by more than a week with respect to unthreaded mushrooms. The mushrooms are exposed to UV-light.
    Type: Application
    Filed: September 12, 2003
    Publication date: December 29, 2005
    Applicant: Nederlandse Organisatie voor toegepastnatuurwetenschappelijk Onderzoek TNO
    Inventor: Servatius Notermans
  • Noise reduction panel arrangement and method of calibrating such a panel arrangement
    Patent number: 6959092
    Abstract: Noise reduction arrangement including: a plurality of actuators (3(n)) for generating secondary noise (ps) to reduce primary noise (pp) and being located in a first surface; a plurality of errors sensors (2(m)) located in a second surface parallel to the first surface for sensing a total amount of noise resulting from the primary noise after being reduced by the secondary noise; a plurality of control elements (5(i)) for controlling the actuators (3(n)) based on the sensor outputs, wherein the distance (d) between the first and second surfaces is such that reduction in power RP of the total amount of noise relative to the primary noise within a predetermined frequency band is within the following range: 0.9×RPmax?RP?RPmax in which RPmax is the maximum obtainable reduction in power of the total amount of noise relative to the primary noise, both RP and RPmax being expressed in decibel.
    Type: Grant
    Filed: October 28, 1999
    Date of Patent: October 25, 2005
    Assignee: Nederlandse Organisatie voor Toegepast-Natuurwetenschappelijk Onderzoek TNO
    Inventors: Arthur Perry Berkhoff, Michiel Wilbert Rombout Maria Van Overbeek, Nicolaas Jan Doelman
  • Method for making a dental element
    Patent number: 6955776
    Abstract: The present invention relates to a method for fabricating a functional dental element, such as a crown. According to the invention, use is made of a three-dimensional printing technique. The major advantages of the invention are that no mold is needed anymore, which entails a considerable saving of costs, that a great accuracy is achieved, and that the element can be made of different materials.
    Type: Grant
    Filed: August 24, 2000
    Date of Patent: October 18, 2005
    Assignee: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO
    Inventor: Frits Kornelis Feenstra
  • Method for making a dental element
    Patent number: 6921500
    Abstract: The present invention relates to a method for fabricating a functional dental element, such as a crown. According to the invention, use is made of a three-dimensional printing technique. The major advantages of the invention are that no mold is needed anymore, which entails a considerable saving of costs, that a great accuracy is achieved, and that the element can be made of different materials.
    Type: Grant
    Filed: August 24, 2000
    Date of Patent: July 26, 2005
    Assignee: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO
    Inventor: Frits Kornelis Feenstra