Patents Assigned to TNO
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Patent number: 6916388Abstract: The present invention is directed to a solid propellant for rocket motors, gas generators and comparable devices, comprising a cured composition of hydrazinium nitroformate and an unsaturated hydroxyl terminated hydrocarbon compound.Type: GrantFiled: May 19, 1999Date of Patent: July 12, 2005Assignee: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNOInventors: Jeroen Louwers, Antonius Eduard Dominicus Maria Van Der Heijden, Petrus Johannes Maria Elands
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Patent number: 6904399Abstract: Disclosed is a simulation based environment that allows a product based engineer, with a modest understanding of complex software programs, to use complex math models. The system provides an interface by which basic component models can be used within the simulation. Allowances are made for particular variables to be adaptable by the product based engineer.Type: GrantFiled: April 23, 2002Date of Patent: June 7, 2005Assignees: Key Safety Systems, Inc., TNO Madymo North AmericaInventors: John Cooper, Paul Francis Altamore, William Edward Rockwell
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Patent number: 6882895Abstract: A method for manufacturing a product having locally specific properties, the geometric form of which is described by a collection of polygonal basic figures in particular in STL (structural triangulation language), comprises the following steps: selecting the above basic figures a face part composed of coherent basic figures, adding to that face part at least one specific property, which during the manufacture of the product is to be given to the part thereof that comprises the above face part, optionally repeating the above process steps for other face parts to be selected, and manufacturing the product on the basis of the then obtained model information by means of a technique adding material in layers or in a die molding process, which includes giving the associated specific property during the building up in layers of at least the part of the product that comprises the above face part or during the injection molding.Type: GrantFiled: November 1, 2000Date of Patent: April 19, 2005Assignee: Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek TnoInventors: German Enrique Knoppers, Jeroen van den Hout
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Patent number: 6867026Abstract: The present invention describes a protein having glucosyltransferase activity. This protein is derived from lactobacilli, which are food-grade microorganisms with the Generally Recognized As Safe (GRAS) status. The protein produces a glucan with a unique structure having 4-linked, 6-linked and 4,6-linked anhydroglucose units or in the presence of suitable acceptors, oligosaccharides. According to the invention lactobacilli capable of producing this glucan using the novel glucosyltransferase can be used as a probiotic or symbiotic.Type: GrantFiled: November 29, 2001Date of Patent: March 15, 2005Assignee: Nederlandse Organisatie Voor Toegepast Natuurwetenschappelijk Onderzoek TNOInventors: Gerritdina Hendrika Van Geel-Schutten, Lubbert Dijkhuizen, Hakim Rahaoui, Robert-Jan Leer
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Patent number: 6841016Abstract: The invention is directed to a process for the production of crystalline energetic materials having improved stability and/or decreased sensitivity by crystallization of the energetic materials with ultrasonic vibration having a frequency of between 10 and 100 kHz.Type: GrantFiled: March 2, 2000Date of Patent: January 11, 2005Assignee: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNOInventors: Wilhelmina Helena Maria Veltmans, Franciscus Johannes Maria Wierckx
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Patent number: 6831173Abstract: A process for producing aldehydes, and/or carboxylic acids is described, in which a primary alcohol, especially a carbohydrate, is oxidized using a catalytic amount of a nitrosonium compound obtained by oxidizing a nitroxyl compound in the presence of an enzyme compound capable of oxidation. Further described are oxidized carbohydrates containing at least 1 cyclic monosaccharide chain group carrying a carbaldehyde group per 25 monosaccharide units and per molecule.Type: GrantFiled: November 26, 2001Date of Patent: December 14, 2004Assignee: Nederlandse Organisatie voor Toegepast-Natuurwetenschappelijk Onderzoek TNOInventors: Jan Matthijs Jetten, Ronald Tako Marinus Van Den Dool, Wim Van Hartingsveldt, Mario Tarcisius Raymundus Van Wandelen
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Patent number: 6815489Abstract: The invention relates to a method for preparing a composition for coating, wherein a layered, inorganic filler is subjected to an ion exchange with a modifier, which modifier comprises at least two ionic groups, which groups are separated from each other by at least four atoms, and wherein the modified filer, together with a polymer, is dispersed in a diluent.Type: GrantFiled: May 13, 2002Date of Patent: November 9, 2004Assignee: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNOInventors: Hartmut Rudolf Fischer, Lawrence Fabian Batenburg, Harmen Anne Meinema, Marinus Pieter Hogerheide, Cornelis Hermanus Arnoldus Rentrop
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Patent number: 6811599Abstract: A biodegradable thermoplastic material comprising a natural polymer, a plasticizer and an exfoliated clay having a layered structure and a cation exchange capacity of from 30-250 milliequivalents per 100 grams and a process of preparing a biodegradable thermoplastic material comprising preparing a suspension of clay, combining said suspension with a natural polymer and a plasticizer and extruding the resultant composition at a temperature of 35-200° C.Type: GrantFiled: December 9, 2002Date of Patent: November 2, 2004Assignee: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNOInventors: Hartmut Rudolf Fischer, Sabine Fischer
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Patent number: 6812272Abstract: The invention relates to a nanocomposite material on the basis of a clay having a layered structure and a cation exchange capacity of from 30 to 250 milliequivalents per 100 gram, a polymeric matrix and a block copolymer or a graft copolymer, which block copolymer or graft copolymer comprises one or more first structural units (A), which are compatible with the clay, and one or more second structural units (B), which are compatible with the polymeric matrix.Type: GrantFiled: November 1, 2002Date of Patent: November 2, 2004Assignee: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNOInventor: Hartmut Rudolf Fischer
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Publication number: 20040185537Abstract: The present invention describes two novel proteins having fructosyltransferase activity. Both enzymes are derived from lactobacilli, which are food-grade micro-organisms with the Generally Recognized As Safe (GRAS) status. One of these proteins produces an inulin and fructo-oligosaccharides, while the other produces a levan and fructo-oligosaccharides. According to the invention lactobacilli capable of producing an inulin and/or a levan and/or fructo-oligosaccharides using one or both of the fructosyltransferases can be used as a probiotic or a symbiotic.Type: ApplicationFiled: March 4, 2004Publication date: September 23, 2004Applicant: NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNOInventors: Sacha Adrianus Fokke Taco Van Hijum, Gerritdina Hendrika Van Geel-Schutten, Lubbert Dijkhuizen, Hakim Rahaoui
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Patent number: 6781740Abstract: The present invention relates to an achromatic phase shift device (1) for introducing a wavelength independent optical phase shift in a first optical beam (40) during operation, comprising at least one dispersive element (55k) formed by first refractive means (2k) and second refractive means (4k), the first refractive means (2k) having a first refractive means input plane (6) for receiving the first optical beam (40) and a first refractive means output plane (8) being at a predetermined angle (&bgr;) to each other, the second refractive means (4k) having a second refractive means input plane (10) and a second refractive means output plane (12) being positioned parallel to the first refractive means input plane (6). The device may comprise further pairs (55k) of respective first and second refractive means (2k, 4k). The present invention also relates to an interferometer comprising at least one achromatic phase shift device.Type: GrantFiled: June 12, 2002Date of Patent: August 24, 2004Assignee: Nederlandse Organisatie voor Toegepast-Natuurwetenschappelijk Onderzoek (TNO)Inventors: Josephus Johannes Maria Braat, Hendrik Bokhove
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Patent number: 6775565Abstract: Imaging apparatus for representing an image of concentration ratios between a first and a second substance in a region of interest of an object, with different measuring values being represented with different colors and/or gray shades. The apparatus comprises a light source capable of irradiating the object with light, which light comprises at least three wavelengths &lgr;1, &lgr;2 and &lgr;3, &lgr;3 being an isobestic wavelength, &lgr;1 being a wavelength at which the first substance has a lower absorption than the second substance, and &lgr;2 being a wavelength at which the first substance has a higher absorption than the second substance. The apparatus further comprises detection means comprising a matrix of pixel detectors, for representing a virtually instantaneous image of the region of interest.Type: GrantFiled: April 18, 2002Date of Patent: August 10, 2004Assignee: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNOInventor: Fokko Pieter Wieringa
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Patent number: 6743364Abstract: Method and system for processing and evaluating data from combination chromatographic and mass spectrometric data. The methods and system comprise data smoothing and determination of an quality factor for a chromatogram of a data set based on a determined entropy value. In one embodiment, the methods and system further comprise data baseline correction prior to entropy value determination. In a further embodiment, a correlation is determined between chromatograms processed according to the invention and one or more chromatograms of one or more data sets. Preferably, said correlation is performed using a multivariate analysis.Type: GrantFiled: August 2, 2001Date of Patent: June 1, 2004Assignee: Nederlandse Organisatie voor Toegepast-Natuurwetenschappelijk Onderzoek TNOInventor: Jan van der Greef
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Patent number: 6742330Abstract: A diesel powered vehicle is provided with an SCR system which uses an external reducing reagent to convert NOx emissions in a manner which accounts for the effects of NOx transient emissions on the reducing catalyst. Actual NOx emissions produced by the engine are filtered using a variable NOx time constant in turn correlated to the reductant/NOx storage capacity of the reducing catalyst at its current temperature to account for changes in the SCR system attributed to NOx transient emissions. Catalyst temperature is filtered using a variable catalyst time constant corresponding to current space velocity of the exhaust gas to account for changes in the catalyst temperature attributed to NOx transient emissions. The reductant is metered on the basis of the filtered, corrected NOx concentration applied at a NSR ratio based, in turn, on the filtered, corrected reducing catalyst temperature.Type: GrantFiled: April 26, 2002Date of Patent: June 1, 2004Assignees: Engelhard Corporation, TNO AutomotiveInventor: Mathijs Van Genderen
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Patent number: 6733988Abstract: The invention uses the existence of tissue-specific telopeptide lysyl hydroxylases, enzymes that hydroxylate lysine residues of the telopeptides of collagen, and the discovery that collagen molecules cross-linked by hydroxyallysine (derived from telopeptide hydroxylysine) are less susceptible to degradation/turnover than collagen molecules cross-linked by means of allysine (derived from telopeptide lysine) due to a different intrafibrillar packing of said collagen molecules. Further, the invention contemplates that one of the characteristics of collagen in scars and other fibrotic tissues is an increase in hydroxyallysine derived cross-links (making the collagen less susceptible to proteolytic breakdown), that this increase in hydroxyallysine cross-links is due to increased levels of telopeptide lysyl hydroxylase, and that telopeptide lysyl hydroxylase plays an important role in the excessive accumulation of collagen in fibrosis/scarring.Type: GrantFiled: November 29, 1999Date of Patent: May 11, 2004Assignee: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNOInventors: Johannes Maria TeKoppele, Rudolf Antonius Bank
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Patent number: 6730502Abstract: The present invention describes two novel proteins having fructosyltransferase activity. Both enzymes are derived from lactobacilli, which are food-grade micro-organisms with the Generally Recognized As Safe (GRAS) status. One of these proteins produces an inulin and fructo-oligosaccharides, while the other produces a levan and fructo-oligosaccharides. According to the invention lactobacilli capable of producing an inulin and/or a levan and/or fructo-oligosaccharides using one or both of the fructosyltransferases can be used as a probiotic or a symbiotic.Type: GrantFiled: November 29, 2001Date of Patent: May 4, 2004Assignee: Nederlandse Organisatie voor Toegepast - Natuurwetenschappelijk Onderzoek TNOInventors: Sacha Adrianus Fokke Taco Van Hijum, Gerritdina Hendrika Van Geel-Schutten, Lubbert Dijkhuizen, Hakim Rahaoui
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Patent number: 6723524Abstract: An immunoassay, e.g. ELISA, method and kit for determining (preferably quantitatively) an analyte adsorbed at a surface or present in a liquid sample, comprising binding the analyte to a solid phase, attaching a marker to the analyte, and detecting marker attached to the solid-phase. The invention proposes to use a combination of marker and detection (e.g. an enzyme-substrate combination) which is capable of producing a precipitate on a solid phase which carries the marker and to detect the binding of analyte to the solid phase by in-situ determining the change in surface mass of the solid phase due to the formation of the precipitate. Ellipsometry is an example of a technique suitable for determining the change of surface mass of the solid phase, which could be made of a silicon- or chromium-sputtered glass slide The invention shortens the assay time and/or improves the assay sensitivity, and allows to measure extremely low surface concentrations of analytes of interest.Type: GrantFiled: May 31, 2000Date of Patent: April 20, 2004Assignee: Nederlandse Organisatie voor toegepastnatuurwetenschappelijk Onderzoek TNOInventors: Willem Theodoor Hermens, Markus Robers, Cornelis Erik Hack, Lucien Adrianus Aarden
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Patent number: 6716355Abstract: The following process steps are carried out in order to purify a liquid by membrane distillation, in particular to produce desalinated water from seawater or brackish water or process water: passing a relatively warn vaporising stream of liquid (retentate stream) over a porous membrane, vapour flowing via the pores of the membrane to the other side of said membrane, and condensing said vapour on a relatively cool condenser surface to give a distillate stream, said condenser surface forming the non-porous separation between a feed stream to be purified and said distillate steam, which feed stream is in counter-current with the retentate stream so that an appreciable proportion of the latent heat will be transferred via vapour to the feed stream, and a gas gap with a width of less than 5 mm being present between the porous membrane and the condenser surface.Type: GrantFiled: March 13, 2002Date of Patent: April 6, 2004Assignee: Nederlands Organisatie voor Toegepast-Natuurwetenshappelijk Onderzoek TNOInventors: Jan Hendrik Hanemaaijer, Jan Willem Van Heuven
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Patent number: 6712012Abstract: A control system for an incineration plant, comprising an incineration furnace with a combustion path along which the material to be burned is transported, air supply means, a steam generator, and control means with a steam controller and an oxygen controller which, depending on respectively the generated amount of steam and the oxygen in the furnace, generate control signals for adjusting the size and/or speed of a stream of material in the furnace and/or adjusting the air supplied. The control signals control the generated amount of steam to a first adjusting value and via air supplied the amount of oxygen to a second adjusting value.Type: GrantFiled: September 3, 2002Date of Patent: March 30, 2004Assignee: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNOInventor: Lambertus Bernardus Maria van Kessel
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Patent number: 6712131Abstract: The exchanger is made from a number of tubes sealingly connected to a pipe plate which is further connected to an enclosure. The pipe plate is realized by positioning enclosure and tubes in a mould and pouring a ceramic slurry which is subsequently sintered.Type: GrantFiled: November 27, 2000Date of Patent: March 30, 2004Assignee: Nederlandse Organisatie Voor Toegepast - Natuurwetenschappelijk Onderzoek TNOInventors: Hendrik Willem Brinkman, Harrie Gorter, Rinse Alle Terpstra, Johannes Coenradus Theodorus Van Der Heijde, Joost Petrus Gerardus Maria Van Eijk, Godefridus Hendricus Maria Gubbels