Patents Assigned to Trustee
  • Quantum dot solar cell with quantum dot bandgap gradients
    Patent number: 8395042
    Abstract: Efficient photovoltaic devices with quantum dots are provided. Quantum dots have numerous desirable properties that can be used in solar cells, including an easily selected bandgap and Fermi level. In particular, the size and composition of a quantum dot can determine its bandgap and Fermi level. By precise deposition of quantum dots in the active layer of a solar cell, bandgap gradients can be present for efficient sunlight absorption, exciton dissociation, and charge transport. Mismatching Fermi levels are also present between adjacent quantum dots, allowing for built-in electric fields to form and aid in charge transport and the prevention of exciton recombination.
    Type: Grant
    Filed: March 24, 2009
    Date of Patent: March 12, 2013
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Honda Motor Co., Ltd
    Inventors: Neil Dasgupta, Friedrich B. Prinz, Timothy P. Holme, James F Mack
  • Printable semiconductor structures and related methods of making and assembling
    Patent number: 8394706
    Abstract: The present invention provides a high yield pathway for the fabrication, transfer and assembly of high quality printable semiconductor elements having selected physical dimensions, shapes, compositions and spatial orientations. The compositions and methods of the present invention provide high precision registered transfer and integration of arrays of microsized and/or nanosized semiconductor structures onto substrates, including large area substrates and/or flexible substrates. In addition, the present invention provides methods of making printable semiconductor elements from low cost bulk materials, such as bulk silicon wafers, and smart-materials processing strategies that enable a versatile and commercially attractive printing-based fabrication platform for making a broad range of functional semiconductor devices.
    Type: Grant
    Filed: October 11, 2011
    Date of Patent: March 12, 2013
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Ralph G. Nuzzo, John A. Rogers, Etienne Menard, Keon Jae Lee, Dahl-Young Khang, Yugang Sun, Matthew Meitl, Zhengtao Zhu, Heung Cho Ko, Shawn Mack
  • Nano-patterned electrolytes in solid oxide fuel cells
    Patent number: 8394550
    Abstract: A nano-patterned membrane electrode assembly (MEA) is provided, which includes an electrolyte membrane layer having a three-dimensional close-packed array of hexagonal-pyramids, a first porous electrode layer, disposed on a top surface of the electrolyte membrane layer that conforms to a top surface-shape of the three-dimensional close-packed array of hexagonal-pyramids, and a second porous electrode layer disposed on a bottom surface of said electrolyte membrane layer that conforms to a bottom surface-shape of the three-dimensional close-packed array of hexagonal-pyramids, where a freestanding nano-patterned MEA is provided.
    Type: Grant
    Filed: September 14, 2010
    Date of Patent: March 12, 2013
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Honda Motor Co., Ltd
    Inventors: Cheng-Chieh Chao, Yi Cui, Ching-Mei Hsu, Young Beom Kim, Friedrich B. Prinz
  • Methods and compositions for risk stratification
    Patent number: 8394599
    Abstract: The present invention provides an approach for the simultaneous determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of potentiators of cellular activation allows for characterization of such pathways and cell populations.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: March 12, 2013
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Omar D. Perez, Garry P. Nolan, Jonathan M. Irish
  • Imaging arrangements and methods therefor
    Patent number: 8395696
    Abstract: Image data is processed to facilitate focusing and/or optical correction. According to an example embodiment of the present invention, an imaging arrangement collects light data corresponding to light passing through a particular focal plane. The light data is collected using an approach that facilitates the determination of the direction from which various portions of the light incident upon a portion of the focal plane emanate from. Using this directional information in connection with value of the light as detected by photosensors, an image represented by the light is selectively focused and/or corrected.
    Type: Grant
    Filed: April 1, 2011
    Date of Patent: March 12, 2013
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Yi-Ren Ng, Patrick M. Hanrahan, Marc A. Levoy, Mark A. Horowitz
  • Method to estimate 3D abdominal and thoracic tumor position to submillimeter accuracy using sequential x-ray imaging and respiratory monitoring
    Patent number: 8396270
    Abstract: A method of estimating target motion for image guided radiotherapy (IGRT) systems is provided. The method includes acquiring by a kV imaging system sequential images of a target motion, computing by the kV imaging system from the sequential images an image-based estimation of the target motion expressed in a patient coordinate system, transforming by the kV imaging system the image-based estimation in the patient coordinate system to an estimate in a projection coordinate system, reformulating by the kV imaging system the projection coordinate system in a converging iterative form to force a convergence of the projection coordinate system to output a resolved estimation of the target motion, and displaying by the kV imaging system the resolved estimation of the target motion.
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: March 12, 2013
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Paul J. Keall, Per Rugaard Poulsen, Byungchul Cho
  • Functional polyglycolide nanoparticles derived from unimolecular micelles
    Patent number: 8394914
    Abstract: Poly(glycolide) polymers are disclosed. The polymers generally include a glycolide-based polymer backbone that includes one or more functional groups such as alkynyl groups, hydrophilic organic triazole groups, hydrophobic organic triazole groups (also including amphiphilic organic triazole groups), di-triazole organic crosslinking groups, and triazole-substituted drug derivatives. The alkynyl groups provide reactive sites for further functionalization of the polymer, for example by reaction with azide derivatives. The polymers can further encapsulate a drug for delivery to a patient (i.e., as compared to drug derivatives that are covalently attached to the polymer). The polymers can be in the form of thermodynamically stable unimolecular micelles or crosslinked nanoparticles. The polymer compositions are completely biodegradable and hold great potential for use in biomedical applications.
    Type: Grant
    Filed: July 22, 2009
    Date of Patent: March 12, 2013
    Assignee: Board of Trustees of Michigan State University
    Inventors: Gregory L. Baker, Milton R. Smith, III, Erin Vogel
  • Separation and contrast enhancement of overlapping cast shadow components and target detection in shadow using polarization
    Patent number: 8396319
    Abstract: Shadow is an inseparable aspect of all natural scenes. When there are multiple light sources or multiple reflections several different shadows may overlap at the same location and create complicated patterns. Shadows are a potentially good source of information about a scene if the shadow regions can be properly identified and segmented. However, shadow region identification and segmentation is a difficult task and improperly identified shadows often interfere with machine vision tasks like object recognition and tracking. A shadow separation and contrast enhancement method based on the polarization of light is provided. Polarization information of scenes is captured by a polarization-sensitive camera and the scenes are processed to effectively separate shadows from different light sources.
    Type: Grant
    Filed: July 17, 2007
    Date of Patent: March 12, 2013
    Assignee: The Trustees Of The University Of Pennsylvania
    Inventors: Edward N. Pugh, Jr., Nader Engheta, Shih-Schon Lin, Konstantin Yemelyanov
  • High performance femoral knee prostheses
    Patent number: 8394147
    Abstract: Knee prostheses featuring components that more faithfully replicate the structure and function of the human knee joint in order to provide, among other benefits: greater flexion of the knee in a more natural way by promoting or at least accommodating internal tibial rotation in a controlled way, replication of the natural screw home mechanism, and controlled articulation of the tibia and femur respective to each other in a more natural way. In a preferred embodiment, such prostheses include an insert component disposed between a femoral component and a tibial component, the insert component preferably featuring among other things a reversely contoured posterolateral bearing surface that helps impart internal rotation to the tibia as the knee flexes.
    Type: Grant
    Filed: November 23, 2010
    Date of Patent: March 12, 2013
    Assignees: Smith & Nephew, Inc., The Trustees of the University of Pennsylvania
    Inventors: Jason Otto, Brian McKinnon, Dean Hughes, Michael Ries, Jan Victor, Johan Bellemans, Jonathan Garino, Timothy Wilton
  • Tibial component of high performance knee prosthesis
    Patent number: 8394148
    Abstract: Knee prostheses featuring components that more faithfully replicate the structure and function of the human knee joint in order to provide, among other benefits: greater flexion of the knee in a more natural way by promoting or at least accommodating internal tibial rotation in a controlled way, replication of the natural screw home mechanism, and controlled articulation of the tibia and femur respective to each other in a more natural way. In a preferred embodiment, such prostheses include an insert component disposed between a femoral component and a tibial component, the insert component preferably featuring among other things a reversely contoured posterolateral bearing surface that helps impart internal rotation to the tibia as the knee flexes.
    Type: Grant
    Filed: November 23, 2010
    Date of Patent: March 12, 2013
    Assignees: Smith & Nephew, Inc., The Trustees of the University of Pennsylvania
    Inventors: Jason K. Otto, Brian McKinnon, Dean Hughes, Michael Ries, Jan Victor, Johan Bellemans, Jonathan Garino, Timothy Wilton
  • Sensitization of tumor cells to radiation therapy through the administration of endothelin agonists
    Patent number: 8394757
    Abstract: Methods to sensitize tumor cells to radiation therapy through the administration of an endothelin agonist such as the ETB agonist IRL1620.
    Type: Grant
    Filed: August 27, 2007
    Date of Patent: March 12, 2013
    Assignees: Spectrum Pharmaceuticals, Inc., The Board of Trustees of the University of Illinois
    Inventors: Anil Gulati, Guru Reddy, Luigi Lenaz
  • Detecting and sorting methylated DNA using a synthetic nanopore
    Patent number: 8394584
    Abstract: Provided are methods for detecting, characterizing or separating DNA based on methylation. Heterogeneous DNA populations are separated based on DNA methylation by providing a membrane having a nanopore through which an electric field is applied. DNA of interest is introduced, and for a given threshold voltage across the nanopore, only DNA having a methylation parameter of interest may transit the pore, thereby facilitating detection, characterization, or separation of DNA based on methylation. The methods are optionally used to detect a disease state that is associated with DNA methylation including, but not limited to, cancer.
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: March 12, 2013
    Assignees: The Board of Trustees of the University of Illinois, The Johns Hopkins University
    Inventors: Gregory Timp, Winston Timp, Andrew Feinberg, Utkur Mirsaidov
  • Control of chemical reactions using isotachophoresis
    Patent number: 8394251
    Abstract: Isotachophoresis (ITP) is exploited to control various aspects of chemical reactions. In a first aspect, at least one of the reactants of a chemical reaction is confined to an ITP zone, but the resulting product of the chemical reaction is separated from this ITP zone by the ITP process. In a second aspect, one or more reactants of a chemical reaction are confined to an ITP zone, and one or more other reactants of the chemical reaction are not confined to this ITP zone. In a third aspect, ITP is employed to confine at least one reactant of a chemical reaction to an ITP zone, and at least one reactant of the chemical reaction is delivered to the ITP zone in two or more discrete doses. These aspects are especially relevant to performing polymerase chain reactions using chemical denaturants as opposed to thermal cycling.
    Type: Grant
    Filed: October 7, 2009
    Date of Patent: March 12, 2013
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Juan G. Santiago, Alexandre Persat
  • Assembly of quasicrystalline photonic heterostructures
    Patent number: 8394708
    Abstract: A method and system for assembling a quasicrystalline heterostructure. A plurality of particles is provided with desirable predetermined character. The particles are suspended in a medium, and holographic optical traps are used to position the particles in a way to achieve an arrangement which provides a desired property.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: March 12, 2013
    Assignees: New York University, The Trustees of Princeton University
    Inventors: David G. Grier, Yael Roichman, Weining Man, Paul Michael Chaikin, Paul Joseph Steinhardt
  • Synthesis of nanoparticles by fungi
    Patent number: 8394421
    Abstract: Systems and methods for synthesizing silver nanoparticles (SNPs) using Trichoderma fungi have been developed. In an aspect, Trichoderma reesei was used for the extracellular synthesis of silver nanoparticles. In the biosynthesis of metal nanoparticle by a fungus, one or more enzymes or metabolites are produced that reduce a salt to its metallic solid nanoparticles through a catalytic process.
    Type: Grant
    Filed: July 29, 2009
    Date of Patent: March 12, 2013
    Assignee: The Board of Trustees of the University of Illinois
    Inventor: G. Ali Mansoori
  • GNA11 MUTATIONS IN MELANOMA
    Publication number: 20130058938
    Abstract: The present invention provides methods of detecting mutations in a GNA11 gene in a melanocytic neoplasm for diagnostic and prognostic purposes. The invention further provides methods of treating such melanocytic neoplasm by modulating the activity of the mutated GNA11 gene.
    Type: Application
    Filed: October 29, 2010
    Publication date: March 7, 2013
    Applicants: The Regents of the University of California, The Board of Trustees of the Leland Stanford Junior University, The University of British Columbia
    Inventors: Boris C. Bastian, Catherine D. Van Raamsdonk, Gregory S. Barsh
  • PHOTOCATALYTIC DISINFECTION OF IMPLANTED CATHETERS
    Publication number: 20130060188
    Abstract: An implantable catheter is provided that may be disinfected without removal from the body of a patient, using a photocatalytic method to activate a reaction on the catheter surface that generates oxidizing agents in the form of Reactive Oxygen Species (“ROS”) and thus destroy microorganisms in a biofilm that is present or forming. A catheter system includes the implantable catheter, a light source, and a source of power operably connected to the light source. Methods are also provided for disinfecting the implantable catheter in vivo.
    Type: Application
    Filed: June 20, 2012
    Publication date: March 7, 2013
    Applicants: The Board of Trustees of the Leland Stanford Junior University, SRI International
    Inventors: William Bedwell, Lorenza Moro, Eric A. Arons, Pablo E. Garcia, Osita Onugha, Sanjeev Dutta, Sarah Young, Karen F. Shakespear, Janus A.J. Haagensen
  • SYSTEMS, DEVICES, AND METHODS FOR CONTINUOUS-TIME DIGITAL SIGNAL PROCESSING AND SIGNAL REPRESENTATION
    Publication number: 20130057423
    Abstract: Systems, devices, and methods for continuous-time digital signal processing and signal representation are disclosed. This includes a continuous-time analog-to-digital converter that is configured to receive an analog signal and convert it to a continuous-time digital signal without using a clock or any type of sampling. This A/D conversion can include a per-level representation and a per-edge representation of the analog signal to produce a digital signal. The digital signal can then be processed in a continuous-time signal processor. The continuous time signal representation and processing can have benefits such a providing filters in high frequency applications where sampling is not practical.
    Type: Application
    Filed: October 12, 2010
    Publication date: March 7, 2013
    Applicants: Commissariat A L'Energie Atomique, The Trustees of Columbia University in the City of New York
    Inventors: Mariya Kurchuk, Colin Weltin-Wu, Yannis Tsividis, Dominique Morche, David Lachartre
  • METHOD AND APPARATUS FOR EXAMINING INNER EAR
    Publication number: 20130060131
    Abstract: An apparatus, for examining an inner ear is provided. An endoscope is provided, comprising a wave guide and an end piece comprising an end window to be placed a first distance from an inner ear, wherein the waveguide focuses light to create a focal plane the first distance from the end window. An optical coherence tomography (OCT) system is connected to a second end of the wave guide and comprises an imaging system connected to the OCT system for generating an image of the inner ear.
    Type: Application
    Filed: August 30, 2012
    Publication date: March 7, 2013
    Applicants: The Texas A&M University System, The Board of Trustees of the Leland Stanford Junior University
    Inventors: John S. Oghalai, Brian Edward Applegate, Simon Shang Gao, Patrick David Raphael
  • SPANNING-TREE PROGRESSION ANALYSIS OF DENSITY-NORMALIZED EVENTS (SPADE)
    Publication number: 20130060775
    Abstract: Methods and systems for determining progression and other characteristics of microarray expression levels and similar information, alternatively using a network or communications medium or tangible storage medium or logic processor.
    Type: Application
    Filed: March 2, 2012
    Publication date: March 7, 2013
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Peng Qiu, Andrew J. Gentles, Sylvia K. Plevritis, Garry Nolan, Karen Sachs