Abstract: The present invention relates to a novel bacterial strain isolated from groundwater. The invention also relates to bacterial extracts and to the use of same in the context of the treatment of inflammations. More particularly, the present invention relates to novel compositions of interest in the treatment and the prevention of inflammatory disorders, notably dermatological pathologies.

Abstract: A process for depositing a layer on at least part of the surface of a substrate by at least partially submerging the substrate in a solution having a solvent and at least one compound intended to form the layer, then drying the substrate, the drying being at least partially carried out in an atmosphere that is isolated from the solution. The submersion in the solution and the drying of the substrate are carried out in the same controlled-atmosphere enclosure.

Abstract: A measurement device for measuring activity of the spinal cord of a vertebrate. The device includes at least one main probe (1) shaped to be fastened to a spinous process (2) of a vertebra (3) and to hold in position on opposite sides of the vertebra at least one emitter (6) for emitting a wave capable of interacting with the spinal cord (7) and at least one associated receiver (8) for receiving the wave that has interacted with the spinal cord and for generating a signal representative of the activity of the spinal cord.

Abstract: The present invention relates to the use of the incretin hormones glucagon-like peptide-1 or GLP-1 and glucose-dependent insulinotropic polypeptide or GIP, or of analogues thereof, in particular the analogues resistant to dipeptidyl peptidase IV, in the treatment of osteoarthritis, in particular for inhibiting or slowing down cartilage destruction.

Abstract: A method of fabricating an elongate structure having a steerable end, the structure including a flexible longitudinal body associated with at least one actuator member having at least one shape memory alloy wire or “SMAW” extending along the body and anchored thereto at its ends, and associated with a mechanism for heating it in controlled manner. The method includes the following steps: inserting at least one of the ends of the SMAW in tubes; crimping the tubes onto the ends of the SMAW; and securing the tubes to the body in such a manner that the wire extends along the body.

Abstract: The present invention relates to a novel bacterial strain isolated from groundwater. The invention also relates to bacterial extracts and to the use of same in the context of the treatment of inflammations. More particularly, the present invention relates to novel compositions of interest in the treatment and the prevention of inflammatory disorders, notably dermatological pathologies.

Abstract: The invention relates to polymer particles in the form of filaments formed by block copolymers, as well as to the use thereof as rheology modifiers for aqueous or organic solutions. A first aspect of the invention relates to filamentous polymer particles having a length/diameter ratio greater than 100, said particles being formed by block copolymers synthesized by controlled radical emulsion polymerization in emulsion, performed using at least one hydrophobic monomer in the presence of a water-soluble marcoinitiator. The invention is characterized in that the filamentous particles are obtained in an aqueous medium for the synthesis of said block copolymers, performed by heating the reaction medium to a temperature of 60 to 120° C., the final block copolymer containing between 10 and 50 mol. % of the water-soluble macroinitiator and the hydrophobic monomer conversion rate being at least 50%.

Abstract: The invention relates to a method for detecting a physiological state of a patient deviating from a reference physiological state, in which, after having determined, in each of Q frequency bands, R reference matrices PRq,r with qe[1 . . . Q] and r?[1 . . . R] which correspond to the reference physiological state, the following steps are repeated in a loop: carrying out measurements, in M time segments, of an electroencephalographic signal; filtering and centering the measurements in Q frequency bands to obtain and determine M×Q scaled matrices of spatial covariance; for each time segment m, calculating a deviation from the reference physiological state, and comparing each of the deviations from the reference physiological state to a predefined threshold. The invention also relates to a monitoring device applying said method.

Abstract: A compound of formula (I-1) wherein n equals 0 or 1, Z represents O or S, R1 represents one group chosen among the group consisting of hydrogen, C1-C7 alkyl, substituted, or not, by a halogen, a hydroxyl or a —O—R12 group, wherein R12 is a C1-C7 alkyl, a group —CH2—O—CO—R5 wherein R5 is chosen among a hydrogen atom and a C1-C7 alkyl, substituted or not by at least one halogen, a group —O—R13, wherein R13 is chosen among hydrogen and a C1-C7 alkyl, an amine or a —CH2— amine, R?1 represents a group chosen among hydrogen and —O—R14, wherein R14 is chosen among hydrogen and a C1-C7 alkyl, and R2 is chosen among the group consisting of a C1-C7 alkyl, a C3-C6 cycloalkyl, an aryl group, and an heteroaryl group for the treatment of pathologies involving excess activity of at least one member of the kallikrein family.

Abstract: The invention relates to peptides useful for inhibiting IGF-1 activity and their use as agents for inhibition of in vitrocell proliferation and for treatment of various diseases.

Abstract: The present invention relates to an apparatus for the treatment of a brain affection, which comprises at least one implantable generator (4) made of non-ferromagnetic material comprising a casing (7), an ultrasound generating treating device (11) positioned into said casing to induce brain affection treatment by emission of ultrasound waves, and means for fastening the implantable casing into the skull. The apparatus further comprises a power controller (PwC) to supply electricity to the treating device of the implantable generator and to set and control its working parameters, and connecting means (6) to connect the power controller and the treating device of the implantable generator. A method for treating a brain affection with such an apparatus is also disclosed.

Abstract: A miniaturized scanning system to generate movement of a flexible device positioned at a distal part of a medical tool. The miniaturized scanning system includes an inner shaft with a longitudinal axis, adapted to guide said flexible device along the longitudinal axis, an abutment comprising an external surface and adapted to maintain said device, and a pusher mechanism adapted to engage with said abutment. The miniaturized scanning system includes at least one end portion adapted to contact said external surface of the abutment at a contact point, wherein said end portion is configured to translate along said longitudinal axis of the inner shaft and wherein the translation of said end portion results in a bending of the device in a bending plane defined by the longitudinal axis of the inner shaft and said contact point.

Abstract: A surgical instrument having an elongated arm and a distal end mounted with a pivot joint on the elongated arm. A drive shaft substantially coaxial with the elongated arm forms a universal joint facing the pivot joint. A distal tool is securely fastened on the drive shaft and rotatively mounted on and in the extension of the distal end of the elongated arm, such that the distal tool has two rotational degree of freedom, distinct and independent of each other, one being around an axis substantially perpendicular to the longitudinal axis of the elongated arm and the other being around an axis substantially collinear to an own axis of the distal tool. The elongated arm includes a plurality of linking elements mounted in series to form the pivot joint. The universal joint is a Cardan joint.

Abstract: The present invention relates to a method of vaccination via hair follicles that makes it possible to target vaccine components to the antigen-presenting cells in order to induce a protective and effective immune response against pathogens.

Abstract: A method for estimating an optical, electromagnetic or acoustic image having at least the successive steps of: scattering an incident optical, electromagnetic or acoustic signal using a multiple scattering medium corresponding to a known transmission matrix stored into a memory of an imaging system; measuring the scattered signal using a detector array and storing the measurements into the memory of the imaging system; and determining an estimated image having a number of image elements that is greater than the number of measurements, at full spatial bandwidth. The estimated image is determined from the measurements and the transmission matrix using a sparsity-promoting algorithm.

Abstract: The invention relates to a titanium based polycarboxylate inorganic-organic hybrid solid material that has a pseudo-cubic crystalline structure, to a method for preparing the same using a solvo-thermal procedure, and to the uses thereof in particular for the storage of gases, the adsorption of liquids, the separation of liquids or gases, and the applications thereof in optics or catalysis, in the biomedical (controlled release drug), cosmetic fields, etc.

Abstract: The percutaneous probe, made in MRI-compatible materials, comprises: a body percutaneously inserted into the tissue of a patient's body organ (8) having a region (10) to be analyzed, treated and monitored during a single medical procedure; at least one information collection sensing device (30,33,34); treatment application transducers (30) 360° disposed to emit focused or defocused therapeutic ultra-sound waves. The computerized system comprises a parametrizable command device (50) adapted to simulate then command a generation of the therapeutic ultra-sound waves, and to monitor the treatment by thermal MRI images.

Abstract: The invention relates to a peptide comprising the following amino acid sequence Thr-Phe-Leu-Lys or Thr-Phe-Leu-Lys-Cys, useful as a CCR2 non competitive antagonist peptide.

Abstract: The invention relates to a device for viewing a digital image comprising means (2) for viewing at least one portion of the digital image. According to the invention, the viewing means include a viewing mask (2) held by a stand (3) such that the viewing mask (2) is used at the eye level of a user such that same can bring his/her eyes closer to the viewing mask in order to examine the portion of the digital image displayed, the viewing mask comprising side extensions (6g, 6d) for protecting the user from outer visual interferences, and in that the viewing device further includes at least one movement handling device (7, 200) that can be controlled by the user in order to control virtual movement of the digital image such that the user is able to view another portion of the digital image.

Abstract: The invention relates to an assistive device for positioning a medical instrument (2) inserted into a natural duct (100) or an artificial duct of a patient relative to an internal organ (P) of a patient, wherein the device comprises a support (1) that is to be inserted at least in part into the body of the patient and supports the medical instrument, means for moving the support, wherein said movement means comprise an articulated arm (9) that includes a plurality of degrees of freedom for moving a proximal end (1a) of the support, means for acquiring images of the internal organ for positioning the medical instrument relative to the internal organ, wherein the image acquisition means comprise a probe (5) supported by the support such that the medical instrument and the probe are rigidly connected, and a control unit (10) for controlling the movement means, which is connected to the image acquisition means and comprises image analyzing means (11) for generating control commands for the articulated arm in orde