Patents Assigned to Universität
  • SYSTEM, COMPONENTS AND METHOD FOR PARAMETRIC MOTION VECTOR PREDICTION FOR HYBRID VIDEO CODING
    Publication number: 20130279566
    Abstract: Parametric Motion Vector Prediction (PMVP) methodologies and components and systems for performing those methodologies are provided to more effectively and efficiently encode video content that includes complex motion such as zoom or rotation. By substituting the PMVP for a collocated MVP used in HEVC in order to reduce the amount of bit rate increase required when including the PMVP analysis in the bit stream. Further, compression of the motion vectors is provided in a three stage approach based on transformation, quantization and difference coding.
    Type: Application
    Filed: April 20, 2012
    Publication date: October 24, 2013
    Applicant: TECHNISCHE UNIVERSITAT BERLIN
    Inventors: Michael TOK, Alexander GLANTZ, Andreas KRUTZ, Thomas SIKORA
  • Beta-lactones as antibacterial agents
    Patent number: 8563598
    Abstract: The present invention relates to specific beta-lactone compounds and compositions thereof for the treatment of infections, such as, e.g., infections with bacteria or infections with protozoa, in particular infections with Gram-positive and/or Gram-negative bacteria and of infectious diseases caused by or related to Gram-positive and/or Gram-negative bacteria, and to the modulation of virulence of Gram-positive and/or Gram-negative bacteria or of protozoa by specific beta-lactone compounds. The invention further relates to the use of the compounds or compositions for preventing or eliminating biofilms.
    Type: Grant
    Filed: February 4, 2009
    Date of Patent: October 22, 2013
    Assignee: Ludwig-Maximilians-Universitat Munchen
    Inventors: Stephan A. Sieber, Thomas Böttcher
  • Biological active proteins having increased in vivo and/or in vitro stability
    Patent number: 8563521
    Abstract: Increased in vivo and/or in vitro stability is imparted to a biologically active protein by fusing to an amino acid sequence consisting of at least about 100 amino acid residues, which are Alanine, Serine and Proline, which form a random coil conformation. Specific examples are described. Also described are related nucleic acids, vectors and cells encoding such amino acids; compositions of biologically active proteins fused to a random coil domain, and methods of making and using the compounds and compositions of the invention.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: October 22, 2013
    Assignee: Technische Universitat Munchen
    Inventors: Arne Skerra, Ina Theobald, Martin Schlapschy
  • DIAMOND OPTICAL ELEMENT
    Publication number: 20130270991
    Abstract: A method of manufacturing an optical element, the method comprising: growing a first layer of single crystal diamond material via a chemical vapour deposition technique using a gas phase having a first nitrogen concentration; growing a second layer of single crystal diamond material over said first layer via a chemical vapour deposition technique using a gas phase having a second nitrogen concentration, wherein the second nitrogen concentration is lower than the first nitrogen concentration; forming an optical element from at least a portion of the second layer of single crystal diamond material; and forming an out-coupling structure at a surface of the optical element for increasing out-coupling of light.
    Type: Application
    Filed: August 2, 2011
    Publication date: October 17, 2013
    Applicants: Element Six Limited, UNIVERSITAT STUTTGART
    Inventors: Daniel James Twitchen, Joseph Michael Dodson, Matthew Lee Markham, Fedor Jelezko
  • Antigen-Specific T Cell Receptors and T Cell Epitopes
    Publication number: 20130273647
    Abstract: The present invention relates to efficient methods for providing antigen-specific lymphoid cells. These lymphoid cells may be used to provide antigen specific T cell receptors having a defined MHC restriction and to identify immunologically relevant T cell epitopes. Furthermore, the present invention relates to antigen-specific T cell receptors and T cell epitopes and their use in immunotherapy.
    Type: Application
    Filed: September 19, 2011
    Publication date: October 17, 2013
    Applicants: BIONTECH AG, TRON- Translationale Onkologie an der Universi- ttttatsmedzin der Johannes Gutenberg- UNiversitat, Universitatsmedizin der Johannes Gutterberg- Universital MAinz
    Inventors: Ugur Sahin, Ozlem Tureci, Petra Simon, Tana Omokoko
  • Immunological test for detecting autoantibodies against testicular antigens
    Patent number: 8557606
    Abstract: The present invention discloses an immunological test for the detection and specific determination of autoantibodies against testicular antigens which are associated with inflammation-related fertility disorders of male mammals in a biological sample of a male mammal, in particular the detection of testicular ER-60 autoantibodies and/or transferrin autoantibodies. The immunological test is utilized to detect the presence of immunologically-caused and infection-related infertility in male mammals, particularly in humans.
    Type: Grant
    Filed: October 22, 2009
    Date of Patent: October 15, 2013
    Assignee: Justus-Liebig-Universitat Giessen
    Inventors: Andreas Meinhardt, Monika Fijak
  • Photon pair source and method for its production
    Patent number: 8559479
    Abstract: The invention relates to a method for the production of a photon pair source, which generates entangled photon pairs, having at least one quantum dot, wherein in the method the operational behaviour of the photon pair source is determined by adjusting the fine structure splitting of the excitonic energy level of the at least one quantum dot. It is provided according to the invention for the fine structure splitting of the excitonic energy level to be adjusted by depositing the at least one quantum dot on a {111} crystal surface of a semiconductor substrate.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: October 15, 2013
    Assignee: Technische Universitat Berlin
    Inventors: Momme Winkelnkemper, Andrei Schliwa, Dieter Bimberg
  • Tripodal Bisphosphonate Derivatives
    Publication number: 20130267731
    Abstract: The present invention describes tripodal bisphosphonate derivatives with a flexible basic framework for the functionalisation of surfaces, and methods for their production and use. The central atom of the flexible framework is hereby a tertiary aliphatic carbon atom. A fourth remaining position of the flexible framework is suitable to be optionally functionalised by so-called click reactions, for example with biomolecules, polyethylene glycol or active agents.
    Type: Application
    Filed: September 7, 2011
    Publication date: October 10, 2013
    Applicant: JUSTUS-LIEBIG-UNIVERSITAT GIESSEN
    Inventors: Wolfgang Maison, Elisa Franzmann, Faiza Khalil
  • MEANS AND METHODS FOR DIAGNOSING CANCER USING AN ANTIBODY WHICH SPECIFICALLY BINDS TO BRAF V600E
    Publication number: 20130266962
    Abstract: The present invention relates to the field of diagnostic tests and diagnostic tools. Specifically, contemplated is to a method for diagnosing cancer in a sample of a subject suspected to suffer from cancer comprising contacting the sample with an antibody which specifically binds to the epitope characterized by SEQ ID NO 1 on a BRAF polypeptide under conditions which allow for binding of said antibody to the epitope and determining binding of the antibody to the epitope, whereby cancer is diagnosed. Further contemplated are antibodies which specifically bind to the epitope characterized by SEQ ID NO 1 on a BRAF polypeptide and a device or kit comprising such antibodies.
    Type: Application
    Filed: September 30, 2011
    Publication date: October 10, 2013
    Applicants: RUPRECHT-KARLS-UNIVERSITÄT HEIDELBERG, DEUTSCHES KREBSFORSCHUNGSZENTRUM
    Inventor: Ulrike Zentgraf
  • SYSTEM AND METHOD FOR THE SIMULTANEOUS, NON-INVASIVE ESTIMATION OF BLOOD GLUCOSE, GLUCOCORTICOID LEVEL AND BLOOD PRESSURE
    Publication number: 20130267796
    Abstract: System and method for the simultaneous and non-invasive estimation of blood glucose, glucocorticoid and pressure levels. It comprises an activity module detector for a digitalized signal acquired by a sensor, representing the distal heartbeat of a person, selecting a segment of consecutive signal samples of fixed duration Swindow(t) and using the same to generate sub-windows Sframe(t, n) of shorter duration; a signal processing module which receives the two signals Swindow(t) and Sframe(t, n) and which delivers a vector XF at its output with the parameters of a physiological model and module based on automatic learning, which receives the XF vector and information on a person's characteristics and provides an estimation of blood glucose levels (BGL), systolic pressure levels (SPL), diastolic pressure levels (DPL) and glucocorticoid levels (GCL) at its output.
    Type: Application
    Filed: November 30, 2011
    Publication date: October 10, 2013
    Applicant: UNIVERSITAT POLITECNICA DE CATALUNYA
    Inventor: Enric Enric Monte Moreno
  • METHOD AND AGENTS FOR PRODUCING N-ACETYLNEURAMINIC ACID (NEUNAC)
    Publication number: 20130266987
    Abstract: The invention relates to an isolated nucleic acid molecule comprising at least one promoter that is active in fungal cells of the trichoderma species, wherein a nucleic acid sequence encoding an N-acetylglucosamine-2-epimerase and/or an N-acetylneuraminic acid synthase is operatively bound to each promoter. The at least one promoter that is active in fungal cells is a constitutive promoter.
    Type: Application
    Filed: December 22, 2011
    Publication date: October 10, 2013
    Applicant: TECHNISCHE UNIVERSITÄT WIEN
    Inventors: Astrid Mach-Aigner, Robert Mach, Matthias G. Steiger
  • DERIVATIVES OF STEROID BENZYLAMINES, HAVING AN ANTIPARASITIC ANTIBACTERIAL, ANTIMYCOTIC AND/OR ANTIVIRAL ACTION
    Publication number: 20130266645
    Abstract: The present invention relates to compounds derived from steroids of the general formula (I) wherein L represents a linker and R# represents a steroid residue, the use of compounds of the general formula (I) in medicine and for the prophylaxis and/or the treatment of infectious diseases. Furthermore described are pharmaceutical compositions containing at least one compound of the general formula (I). A further aspect of the invention relates to the synthesis of said compounds of the general formula (I).
    Type: Application
    Filed: October 6, 2011
    Publication date: October 10, 2013
    Applicant: Justus-Liebig-Universitat Giessen
    Inventors: Katja Becker, Reimar Krieg, Bruno Schönecker
  • GENERATION OF NANODISPERSE INCLUSIONS IN A HIGH-VISCOSITY MATRIX
    Publication number: 20130260133
    Abstract: The invention relates to a process for generating a porous material having homogeneous, gas-containing inclusions in the micrometer and sub-micrometer range, and also to the material produced by such process.
    Type: Application
    Filed: December 1, 2011
    Publication date: October 3, 2013
    Applicant: UNIVERSITAT ZU KOLN
    Inventors: Reinhard Strey, Alexander Müller
  • USE OF PROKARYOTIC SPHINGOSINE-1-PHOSPHATE LYASES AND OF SPHINGOSINE-1-PHOSPHATE LYASES LACKING A TRANSMEMBRANE DOMAIN FOR TREATING HYPERPROLIFERATIVE AND OTHER DISEASES
    Publication number: 20130259851
    Abstract: The present invention relates to the use of prokaryotic sphingosine-1-phosphate lyases (S1PL) and S1PLs that lack a transmembrane domain or of a nucleic acid encoding such an S1PL in the prevention or treatment of a disease condition associated with elevated levels of sphingosine-1-phosphate (S1P), and for which S1P elevation is directly or indirectly causative. In addition, the invention relates to a new product in the form of S1PL lacking the N-terminal loop domain.
    Type: Application
    Filed: November 30, 2011
    Publication date: October 3, 2013
    Applicants: UNIVERSITAT ZURICH, UNIVERSITAT BERN
    Inventors: Uwe Zangemeister-Wittke, Andrea Huwiler, Markus G. Grutter, Florence Bourquin
  • Distributive resistive mixer
    Patent number: 8547158
    Abstract: The invention relates to devices comprising field effect transistors to detect the power of an electromagnetic high frequency signal VRF. According to the prior art, the high frequency signal is coupled into the gate G and via a capacitor CGD into the drain D of the field effect transistor FET, the gate G being biased with a direct voltage Vg which corresponds to the threshold value of the FET transistor. The resulting current at the source S contains a direct current portion Ids which is proportional to the square of the amplitude of the high frequency signal. The operating frequency of said power detectors is limited to a few gigahertz (GHz) by the discrete arrangement and especially by the predetermined gate length of the field effect transistor. The aim of the invention is to improve a resistive mixer in such a manner that it can be operated at high gigahertz and terahertz frequencies.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: October 1, 2013
    Assignee: Johann Wolfgang Goeth-Universität Frankfurt a.M.
    Inventors: Ullrich Pfeiffer, Erik Oejefors, Hartmut G. Roskos, Alvydas Lisauskas
  • Chimeric human beta defensins
    Patent number: 8546525
    Abstract: The invention relates to a nucleic acid molecule selected from the group comprising a) a nucleic acid molecule having one of the nucleotide sequences presented in SEQ ID:NO 4 to SEQ ID:NO 8, b) a nucleic acid molecule that codes for a peptide having one of the amino acid sequences presented in SEQ ID:NO 12 to SEQ ID:NO 16, c) a nucleic acid molecule, the complementary strand of which hybridizes to a nucleic acid molecule according to a) or b) and which codes for a peptide having antimicrobial activity, and d) a nucleic acid molecule, the nucleotide sequence of which deviates from the nucleotide sequence of a nucleic acid molecule according to c) because of the degenerated genetic code.
    Type: Grant
    Filed: November 20, 2010
    Date of Patent: October 1, 2013
    Assignee: Christian-Albrechts-Universität zu Kiel
    Inventor: Joachim Grötzinger
  • RECOMBINANT EQUINE HERPESVIRUS-1 VACCINE CONTAINING MUTATED GLYCOPROTEIN C AND USES THEREOF
    Publication number: 20130251747
    Abstract: The present invention provides compositions or vaccines that contain a recombinant EHV-1 that elicit an immune response in animals against equine herpesvirus, including compositions comprising said recombinant EHV-1, methods of vaccination against equine herpesvirus, and kits for use with such methods and compositions.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 26, 2013
    Applicants: FREIE UNIVERSITÄT BERLIN, MERIAL LIMITED
    Inventors: Jean Christophe Audonnet, Jules Maarten Minke, Nikolaus Osterrieder, Guanggang Ma
  • LIPOSOMES CONTAINING PERMEATION ENHANCERS FOR ORAL DRUG DELIVERY
    Publication number: 20130251783
    Abstract: The present invention relates to liposomal compositions and their application for delivery of pharmaceuticals for the treatment of disease.
    Type: Application
    Filed: September 14, 2012
    Publication date: September 26, 2013
    Applicants: Universitat Heidelberg, MULLER-BORE & PARTNER
    Inventors: Johannes Parmentier, Gert Fricker, Felix Gropp, Klaus Hartmann
  • NITRIC OXIDE DONORS IN THERAPY OF NITRIC OXIDE DEFICIENCY-INDUCED DISTURBANCES OF CEREBRAL MICROCIRCULATION
    Publication number: 20130252959
    Abstract: The present invention relates to nitric oxide releasing compounds and their use in the prevention, amelioration and/or therapy of nitric oxide (NO) deficiency induced disturbances of the cerebral microcirculation. The NO deficiency induced disturbances of the cerebral microcirculation may be due to an intracranial hemorrhage or stroke and can cause cerebrovascular spasms (or cerebral vasospasms) (CVS) and/or malperfusion of brain parenchyma caused by blood vessel and blood flow dysregulation which, in turn, can cause secondary neurological deficiencies (DIND) and/or brain infarction. Particularly, the present invention relates to the prevention, amelioration and/or therapy of delayed cerebral vasospasm-associated disorders after survived subarachnoidal hemorrhage by applying a NO-donor, most preferably Molsidomine.
    Type: Application
    Filed: November 25, 2011
    Publication date: September 26, 2013
    Applicant: West-Falische Wilhelms-Universitat Munster
    Inventors: Angelika Ehlert, Christoph Schmidt
  • BONE MARROW APLASIA WITH HAEMORRHAGIC DISEASE IN CALVES CAUSED BY NOVEL PATHOGEN
    Publication number: 20130251719
    Abstract: The present invention refers to a novel circovirus as causative agent of bone marrow aplasia with haemorrhagic disease in cattle. The present invention provides novel nucleic acid and protein sequences for diagnostic and therapeutic uses.
    Type: Application
    Filed: October 22, 2010
    Publication date: September 26, 2013
    Applicants: Tiergesundheitsdienst Bayern E.V., Universitat Leipzig
    Inventors: Hermann Muller, Mohammad Yahya Halami, Jens Bottcher, Eva Kappe, Benjamin Schade