Abstract: A classifying device for classifying cells in real-time, comprising: as alignment unit configured to align a cell to be classified along the cell's major axis; and a classifying unit configured to classify the aligned cell using a multilayer perceptron, MLP; wherein the MLP classifies the aligned cell based on one or more images of the aligned cell. By executing the classifying device, an improved and efficient cell classification in real-time based on cell images can be provided, while labelling of the cells to be classified can be avoided.

Abstract: A method of preparing a mesoporous carbon composite material having a mesoporous carbon phase and preformed metal nanoparticles located within the mesoporous carbon phase. The present invention also relates to a mesoporous carbon composite material and to a substrate having a film of such mesoporous carbon composite material.

Abstract: The operation of a hybrid powertrain system is optimized with respect to a desired state-of-charge trajectory, taking account of the estimated anticipated vehicle drive power. The hybrid powertrain system has an internal combustion engine and an electrically operated torque machine. The internal combustion engine and the torque machine are controlled by a control device and are connected to an output element via a hybrid transmission. Before the start of the prediction period ?t, an experience-based state-of-charge trajectory for the anticipated route, covering at least the prediction period ?t, is retrieved from an external database. The desired state-of-charge trajectory is established based on the experience-based state-of-charge trajectory by modifying it with at least one optimization constraint.

Abstract: An amphiphilic copolymer includes a first block, a second block and a linker covalently linking the first block with the second block, wherein the first block is a hydrophilic dendritic polyglycerol derivative having a polyglycerol backbone and carrying a plurality of sulfate or sulfonate residues substituting hydroxyl groups of the polyglycerol backbone, wherein the second block is a hydrophobic block comprising a polymer chosen from the group consisting of polycaprolactone, a polylactic acid polymer, and a copolymer of lactic acid and glycolic acid. The linker comprises a hydrocarbon having at least six consecutive methylene residues and a cleavable entity. The linker is devoid of a triazole-containing residue resulting from a reaction between an alkyne and an azide.

Abstract: The invention relates to an element in the shape of a sensor, an active electronic component, a switch, a circuit, or an electric conducting path for integration into a surrounding medium. The element is penetrable by the surrounding medium and has a porous, non-conductive substrate and at least one circuit trace made of conductive material present on the substrate. The openings of the substrate are open in an area of the circuit trace. The use and manufacture of the element are also provided.

Abstract: A dual-mode microwave applicator for treating tissue comprises a control unit, a rod-shaped element, a coaxial line, and a metal sleeve. The control unit controls the applicator in an application mode and a sensing mode. In the application mode microwave radiation is applied and during the sensing mode tumorous tissue is detected. The rod-shaped element comprises a tip. The coaxial line is formed in the rod-shaped element to relay microwaves to the tip for treatment of the tissue. The coaxial line comprises an inner conductor and an outer conductor. The outer conductor includes a slot of a slot length formed at a slot distance from the tip. The metal sleeve at a sleeve distance from the slot. The sleeve distance is about 0.55 mm, the slot length is about 1.75 mm, and the slot distance is about 7.7 mm.

Abstract: A method for recycling powdered paint waste is provided in which, the powdered paint waste is being treated with the aid of a reactant in such a way that its adhesion to surfaces and especially to metal surfaces is reduced or eliminated. The treatment of the powdered paint waste allows the powdered paint waste to be additionally processed under the influence of heat and to use it as a starting material in various recycling processes or in other processes.

Abstract: The invention relates to an internal combustion engine that comprises a first Brayton cycle comprising a mixed ionic-electronic conducting (MIEC) membrane that separates the O2 from the air such that the suctioned air current is free from N2; a second Brayton cycle combined in a binary manner with the first Brayton cycle and nested with a cycle selected from an Otto cycle and a diesel cycle performed by means of oxy-combustion. The second Brayton cycle transmits mechanical energy and thermal energy from exhaust gases to the first Brayton cycle. The first Brayton cycle provides to the second Brayton cycle compressed O2 from the MIEC membrane. By means of the present engine, the NOx emission into the atmosphere is prevented by the separation of N2 in the MIEC membrane.

Abstract: The invention relates to a plenoptic ocular device intended to be coupled in an ocular port of an optical instrument configured to generate a real image of a sample on a focal plane situated in a region close to said ocular port, said plenoptic ocular device being configured to capture said real image, generate a set of elemental images and send them to recording means with spatial discretisation which in turn comprises communication means configured to transmit the set of elemental images to external image processing means.

Abstract: The present invention relates to a recombinant virus of the family Paramyxoviridae comprising an expressible polynucleotide encoding at least one of (i) a tumor antigen, (ii) a fragment of a tumor antigen, and (iii) a variant of (i) or (ii). The present invention further relates to a polynucleotide encoding said recombinant virus of the family Paramyxoviridae and to a host cell comprising said recombinant virus of the family Paramyxoviridae and/or said polynucleotide encoding said recombinant virus of the family Paramyxoviridae. Moreover, the present invention relates to a method for activating immune cells with antitumor activity in a sample comprising cancer cells and to further means, methods, and uses related to the present invention.

Abstract: Lattice structure with piezoelectric behavior characterized in that the lattice structure (1) comprises a periodic succession of unitary cells (10), wherein each unitary cell (10) is made of a dielectric material, is bending or torsion dominated and comprises nanometric structural connectors (11) connected to each other through nodes (12) defining a non-centrosymmetric shape having a topological constraint that induces torsion or bending of said structural connectors (11); and wherein the unitary cells (10) are connected to each other at least in series defining a continuous electric potential accumulation path with two opposed ends (2, 3), the unitary cells (10) being arranged within the lattice structure (1) in a non-centrosymmetric disposition accumulating and conducting without cancellation the electric gradient generated on each unitary cell (10) through the lattice structure (1) to said two opposed ends (2, 3).

Abstract: A method for coating one or more channels of a sample using a vapor deposition includes alternatingly supplying at least two gaseous precursor to one or more channels defined in a sample through at least one feed line that is connected to a first channel end of the one or more channels. An adjustable pressure gradient is generated and conducts the at least two gaseous precursors along a first flow direction (SR1) from the at least one feed line to a first discharge line through the one or more channels. The at least two gaseous precursor and reaction products are discharged from the one or more channels through a first discharge line that is connected to a second channel end of the one or more channels of the sample. Non-reacted precursors and reaction products are discharged through a second discharge line that is connected to the first channel end.

Abstract: The present invention relates to a compound, which can be used in the prevention and treatment of infections with pathogenic Neisseria species, in particular N. gonorrhoeae and N. meningitidis (the gonococcus and the meningococcus, respectively), and other pathogenic bacteria (e.g. Haemophilus species or Moraxella catarrhalis), and which can be used for disinfecting a substrate from said bacteria. Moreover, the present invention relates to a corresponding pharmaceutical composition comprising said compound.

Abstract: The present invention relates to a flatbed air-liquid interface exposure module for exposing a plurality of cells at an air-liquid interface to nanoparticles, the flatbed air-liquid interface exposure module comprising a moisturizing section, an exposure section, and an aerosol duct. Further provided are related systems and methods.

Abstract: In a method for setting up a pipeline section of a pipe system in a heat network, which is provided for transferring a heat transfer fluid between a heat provider and a heat consumer, the pipeline section is subdivided into segments in a segmentation step. A segment characteristic variable is determined for each segment based on a physical soil characteristic variable. The determined segment characteristic variables of two adjacent segments differ by more than a predefined segment characteristic variable difference value. In a bedding determination step, segment embedding of a pipeline segment, introduced in the trench in this segment, in a water-permeable segment bedding material is predefined for each segment such that a heat loss of the heat transfer fluid transferred in the pipeline segment, which is averaged over the segment and is based on a unit of length, is lower than a predefined heat loss limit value.

Abstract: The present invention relates to polymeric particles comprising a biodegradable polymer, and at least one microorganism in a total concentration of at least 108 CFU/g dry weight that is stable for at least 35 weeks at 30° C. and optionally additional carriers and additives as well as to methods for producing polymeric particles and use thereof.

Abstract: Conjugates comprising a targeting moiety specific for the CXCR4 and based on the polyphemusin-derived peptide and a therapeutic or imaging agent are provided. Therapeutic and diagnostic methods with the conjugates which require specific targeting to CXCR4+cells are provided as well.

Abstract: Aspects of the present disclosure include conformationally restricted analogs of catecholamine type compounds (e.g., isoprenaline, adrenaline, noradrenaline) which activate ?2AR with high selectivity over ?1AR. The subject beta-2 selective adrenergic receptor agonist compounds may serve as bronchiodilators and find use in the treatment of a variety of bronchoconstrictive diseases and conditions. Also provided are compositions and methods for treating preterm labor. A method of treating acute asthma including administration of a subject compound to a subject in need thereof is provided. The subject method can provide for reduced undesirable side effects associated with non-selective ?-adrenergic receptor agonism, such as inotropic and chronotropic effects that leads to elevated blood pressure. The compounds can also be used to prevent or treat heart failure. Kits and compositions for practicing the subject methods are also provided.

Abstract: A method and an apparatus for processing an object by generation of laser radiation as a collimated laser beam, influencing the intensity distribution and/or the phase progression over the cross section of the laser beam, splitting the laser beam into two partial beams, and deflection and focusing of the partial beams so that the partial beams are superimposed in a processing zone in the material of the object.

Abstract: The invention relates to a method for actively balancing a rotor (1), comprising: providing a device with a rotor (1) that can be rotated around an axis of rotation and a mechanism (2) allocated to the rotor (1) for actively balancing, in which a magnetic fluid (7) is received in a fluid chamber (6) formed on the rotor (1), which partially fills the fluid chamber (6) and contains at least one of the following fluids: ferrofluid and magnetorheological fluid; holding the magnetic fluid (7) by means of a permanent magnetic field of a permanent magnet (5) arranged on the rotor (1) in an initial position in the fluid chamber (6); rotating the rotor (1) around the axis of rotation (3), and passing the fluid chamber (6) and permanent magnet (5) by an electrical exciter system with a fixedly arranged electromagnet (8) during the rotation of the rotor (1), wherein the permanent magnetic field of the permanent magnet (5) and an electromagnetic field of the electromagnet (8) here overlap in an activated state for active