Abstract: The present invention relates to a powder for the preparation of three-dimensional objects comprising, or consisting of, supraparticles (8,9,10) comprising at least a first population of first primary particles, wherein the first primary particles are thermoplastic polymeric particles, wherein the first primary particles have a volume-averaged median particle diameter of from 10 to 2000 nm; wherein the primary particles are agglomerated and/or partially sintered together to form the supraparticles, and/or wherein the supraparticles have a volume-averaged median particle diameter of from 2.5 to 100 pm.

Abstract: A sensing arrangement and corresponding detector device includes a sensing area, for accommodating a sensing substance selected for experimenting an optical response as a response of an external stimulus; a light emitter, for emitting light towards said sensing area; a light receiver, for receiving a light from said sensing area; a substrate having a first substrate surface and a second substrate surface; wherein, said light emitter includes a first LED and the light receiver includes a second LED, both LEDs formed on the first substrate surface; and the sensing arrangement further includes a trench, formed between the first LED and the second LED.

Abstract: A method for aligning the positions and orientations of a real object and a virtual object in real space, the virtual object corresponding to a virtual replica of the real object, the method comprising visualizing at least one alignment feature superimposed on or replacing a representation of the virtual object in a field of view containing the real object, wherein the alignment feature is indicative of a position and orientation of the virtual object in real space, and wherein the at least one alignment feature complements a shape and/or surface pattern of the real object, such that the alignment feature and the real object form a composite object with complementing patterns and/or shapes in the field of view, when the real object and the virtual object are aligned.

Abstract: Disclosed are novel conjugates and processes for the preparation thereof.

Abstract: The present invention relates to the use of a porous polymer etched ion-track membrane as separator for batteries comprising a positive electrode, a negative electrode and a liquid electrolyte comprising at least one salt of a cationic ion in solution in a solvent, and to batteries comprising such a membrane as porous separator.

Abstract: The present disclosure relates to a routing circuit for routing signals between neuron circuits of an artificial neural network, the routing circuit comprising: a first memory cell (302) having an input coupled to a first input line (304) of the routing circuit and an output coupled to a first column line (308); a second memory cell (302) having an input coupled to a second input line (304) of the routing circuit and an output coupled to the first column line (308); and a first comparator circuit (310) configured to compare a signal (IREAD1) on the first column line (308) with a reference level, and to selectively assert a signal (VOUT1) on a first output line (312) of the routing circuit based on the comparison.

Abstract: The present invention relates to polypeptide consisting of three TNF homology domains of TNF-ligand family members proteins (THD) that specifically bind to the extracellular part of TNFR2, wherein C-terminal and N-terminal reference points are defined by consensus sequences. The THIDs are linked by short stretches of further C-terminal and/or N-terminal amino acids of the THD or variants thereof as well as by peptide linkers. These peptides have an improved stability. Furthermore the invention relates to polypeptide multimers comprising several of the polypeptides of the present invention.

Abstract: The present invention relates to a sigma-delta analogue-to-digital converter. The sigma-delta analogue-to-digital converter comprises a transconductance stage having first, second and third terminals. A capacitor is connected in parallel at the third terminal. Further, the sigma-delta analogue-to-digital converter comprises a quantiser at the third terminal of the transconductance stage with feedback by a voltage digital-to-analogue converter for feeding back a feedback signal to one of the terminals of the transconductance stage.

Abstract: The invention relates to a process for the preparation of acetals from carbon dioxide. The invention also relates to a mixture of phosphorus containing ligands comprising least one polydentate ligand and at least one monodentate ligand. Further, the invention also relates to the use of mixtures comprising at least one polydentate ligand and at least one monodentate ligand in transition metal complexes for the preparation of acetals.

Abstract: The present invention relates to a cluster of differentiation 98 heavy chain (CD98hc)-specific binding protein, wherein the CD98hc-specific binding protein is a lipocalin 2 (Lcn2)-derived binding protein and binds to CD98hc with a KD of 200 nM or lower.

Abstract: The present invention relates to the compound (4,5,5-trimethyl-3-methylenecyclopent-1-en-1-yl)methyl acetate and to an attractant composition for insects of the species Delottococcus aberiae comprising said compound. The present invention also relates to an attractant device for Delottococcus aberiae comprising said compound or said composition, and to a method for the control and/or monitoring of the populations of insects of the species Delottococcus aberiae.

Abstract: The invention relates to a method for diagnosing a tumour disease in an isolated sample, comprising the amplification of methylated DNA sequences, to a kit for diagnosing a tumour disease, and to the use of the method and/or of the kit for the diagnosis and/or progress control of a malignant tumour disease, in particular of prostate, breast, ovarian or colorectal carcinomas. The invention furthermore relates to a computer program product comprising risk score analysis commands for diagnosing a tumour disease, and to a data processing device.

Abstract: An electrode suitable for constructing an electrochemical double layer capacitor and/or supercapacitor is provided that includes an electrode material a metal organic framework (MOF), wherein the MOF includes an inorganic building unit including metal atoms selected from group 1 to group 12 elements, and functional groups of organic linkers including oxygen (O) and one or more atoms selected from the group comprising phosphorus (P), arsenic (As), antimony (Sb), silicon (Si), selenium (Se) and bismuth (Bi). The functional groups of the organic linkers can include phosphonate, arsonate, phosphonic acid, phosphinic acid, arsonic acids and/or arsenic acids, monoester and/or diester forms thereof. Further, the metal atoms may be selected from zinc (Zn), cadmium (Cd), copper (Cu), cobalt (Co), nickel (Ni), gold (Au) and silver (Ag). The use of the MOF as a semiconductor in semiconductor applications, a semiconductive device, such as a photovoltaic cell, including the MOF are also provided.

Abstract: The invention relates to a method for producing a bioartificial and primarily acellular fibrin-based construct, wherein a mixture of cell-free compositions containing fibrinogen and thrombin is applied to a surface and subsequently pressurised. An additional aspect of the invention is directed to such fibrin-based bioartificial acellular constructs obtained according to the invention, with improved biomechanical properties, as well as to the use of same in the field of implantology, cartilage replacement or tissue replacement.

Abstract: The present invention relates to methods and compositions for stimulating an immune response. In particular, the present invention relates to immunostimulatory RNA molecules comprising sequences derived from an Influenza A virus nucleoprotein-encoding RNA molecule that act as adjuvants and/or immunostimulatory agents to enhance host immune responses.

Abstract: The invention pertains to the technical fields of bioanalytics and agriculture, and relates to a method and to an assembly for in-ovo sexing of bird eggs. The aim of the present invention is to provide a method and an assembly by means of which in-ovo sexing of bird eggs is achieved with a stable predictive accuracy of the sex and which are simple and cost-effective. The aim is achieved using a method and an assembly in which a fertilised bird egg incubated for 3 to 9 days is irradiated with at least two light-emitting laser beam sources with different excitation waves after the shell is opened, the captured and processed fluorescence scattering spectra and Raman scattering spectra being used, as complementary spectra associated with the different excitation wavelengths, to determine a classification value, and the sex being determined by comparing the determined classification value with an intrinsically determined threshold value. The method and the assembly can be used for sexing farm poultry.

Abstract: The invention relates to an element (1) for compensation of tolerances and/or gap widths of a device, having a main body (2) which has at least one annular cross-sectional portion (3), wherein the cross-sectional portion (3) has, in its peripheral direction (4), at least one auxetic portion (5) which exhibits auxetic behavior in a radial direction (6) of the main body (2). The invention also relates to an engine (20) which comprises the element (1), to an assembly method for a shaft/hub connection (19) which has at least one element (1), and to an adaptation method for adapting a tolerance and/or a gap width in the engine (20).

Abstract: A cryostat for operation with liquid helium, may comprise a primary chamber with a main region and a pot region for containing a bath of liquid helium-4, primary inlet means for introducing liquid helium-4 and primary outlet means for releasing gaseous helium-4, the primary inlet means comprising a transfer line extending into the primary region. The cryostat may be configured for operation under a continuous supply of liquid helium-4 and at a reduced helium-4 pressure, whereby gaseous helium-4 is pumped off through the outlet means. The primary chamber may comprise a baffle structure arranged between the pot region and the main region, the baffle structure defining at least one flowpath for the flow of gaseous helium-4, each flowpath forming a detoured connection between the pot region and the main region.

Abstract: The present invention relates to a microfluidic device (1; 8) for the production of cellular spheroids comprising at least one chamber (2; 9) comprising a fluid inlet (3) for introducing fluid into the chamber (2; 9) and a fluid outlet (4) for removing said fluid from the chamber (2, 9), wherein said at least one chamber (2; 9) comprises a base formed by a substrate (5; 10) comprising at least two recesses (6; 11) to collect a fluid comprising biological cells when the substrate (5, 10) is contacted with the fluid, wherein the size of the at least two recesses (6; 11) decreases from the fluid inlet (3) to the fluid outlet (4) of the at least one chamber (2; 9).

Abstract: In various embodiments a module for generating an interference pattern for producing a digital holographic image is provided.