Patents Assigned to Universiteit Gent
  • Patent number: 11368164
    Abstract: An interleaver for combining at least two incoming signals into an analog output signal includes at least a first signal path and a second signal path. Each signal path has: an input terminal, a first gain stage for multiplying a signal coming from the input terminal with a first gain (a) to obtain a first signal, a mixer and a second gain stage for multiplying a signal coming from the input terminal with a second gain (b) before or after mixing it with a clock signal to obtain a second signal, an adder for adding the first and second signal to obtain an output signal of the signal path wherein the first and second gain are different from zero. The interleaver comprises an adder for adding the output signals from the signal paths.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: June 21, 2022
    Assignees: UNIVERSITEIT GENT, IMEC VZW
    Inventors: Guy Torfs, Hannes Ramon, Xin Yin
  • Patent number: 11360262
    Abstract: An integrated wavelength-selective filter device comprises a first optical element, for directing received radiation into a direction defined by a first angle, and a second optical element being a diffractive element configured for diffracting the directed radiation under a second angle. The second angle is such that for a single reference wavelength the diffracted radiation is directed into a propagation medium for advancing therein towards a predetermined position on the first optical element or on a further optical element for filtering radiation having a wavelength substantially matching the reference wavelength from radiation having a substantially different wavelength. The propagation medium is formed from a material that is different from any material of the substrate of the first and the second optical element.
    Type: Grant
    Filed: December 31, 2018
    Date of Patent: June 14, 2022
    Assignees: UNIVERSITEIT GENT, IMEC VZW
    Inventors: Roeland Baets, Eva Ryckeboer, Abdul Rahim, Anton Vasiliev, Xiaomin Nie
  • Patent number: 11358997
    Abstract: The present invention relates to a fusion protein comprising at least two cytokines, of which at least one is a modified cytokine with a strongly reduced binding affinity to its receptor, or to one of its receptors. Preferably, both cytokines are connected by a linker, preferably a GGS linker. The invention relates further to said fusion protein for use in treatment of diseases.
    Type: Grant
    Filed: August 14, 2018
    Date of Patent: June 14, 2022
    Assignees: VIB VZW, Universiteit Gent, Centre National De La Recherche Scientifique, Université De Montpellier, Centre Hospitalier Regional Universitaire de Montpellier
    Inventors: Jan Tavernier, Jennyfer Bultinck, Sarah Gerlo, Gilles Uze, Franciane Paul, Yann Bordat
  • Patent number: 11357853
    Abstract: A treatment of cancer, particularly the treatment of neuroblastoma. Indeed, the discloses that a particular long non-coding RNA (lncRNA) is specifically up-regulated in neuroblastoma cells as compared to other cancer cells and that high expression of the lncRNA correlates with a lower survival probability. Inhibition of this lncRNA in neuroblastoma cells leads to a reduction in cell growth and induction of apoptosis and is a novel therapeutic strategy in the treatment of neuroblastoma.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: June 14, 2022
    Assignee: Universiteit Gent
    Inventors: Dries Rombaut, Pieter Mestdagh, Steve Lefever
  • Patent number: 11357102
    Abstract: In a first aspect, the present disclosure relates to a method for designing a pattern of a stress relief layer for a flat device to be transformed into a shape-retaining non-flat device by deformation of the flat device. The flat device (and thus also the non-flat device) may comprise at least two components and at least one electrical interconnection between two components. In a second aspect, the present disclosure is related to a method of manufacturing a shape-retaining non-flat device by deformation of a flat device, wherein the flat device is attached to a patterned stress relief layer designed in accordance with the first aspect of the present disclosure. In preferred embodiments, the stress relief layer is a thermoplastic layer or a layer comprising a thermoplastic material and deformation of the flat device comprises deformation by a thermoforming process, after attachment of the flat device to the stress relief layer.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: June 7, 2022
    Assignees: IMEC VZW, Universiteit Gent
    Inventor: Andres Felipe Vasquez Quintero
  • Patent number: 11356683
    Abstract: A transcoder for transcoding a basic representation of a videostream into one or more arbitrary representations comprises: a receiver adapted for receiving the basic representation and at least one frame information set comprising one or more frame information packets; a decoder adapted for decoding the basic representation; a re-encoder adapted for selecting at least one frame information set and for selecting one or more frame information packets from this at least one frame information set for forming a arbitrary representation, the re-encoder is adapted for extracting coding information from the frame information packets, and for re-encoding the decoded basic representation using the coding information thereby obtaining the one or more arbitrary representations.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: June 7, 2022
    Assignees: UNIVERSITEIT GENT, IMEC VZW
    Inventors: Johan De Praeter, Glenn Van Wallendael, Peter Lambert
  • Publication number: 20220169604
    Abstract: The present invention in general relates to the field of bioconjugation. More in particular, the invention relates to novel bioconjugation reactants based on an ?,? unsaturated ?-hydroxylactam structure, amongst others allowing a higher degree of functionalization compared to classical bioconjugation reactants such as maleimide. The present invention also provides methods of preparing the novel bioconjugation reactants, as well as uses thereof in human and/or veterinary medicine; and conjugation processes.
    Type: Application
    Filed: February 28, 2020
    Publication date: June 2, 2022
    Applicant: Universiteit Gent
    Inventors: Annemieke Madder, Ewout De Geyter, Eirini Antonatou, Sabina Smolen, Dimitris Kalaitzakis, Georgios Vassilikogiannakis
  • Patent number: 11349729
    Abstract: An enhancement device (10, 116) for enhancing service requests (120) and a method of allocating network resources to a network service in a communication network is provided. The communication network comprises network resources capable of providing a network service specified in a service request issued by a client. The service request (120) comprises a direct part (121) and an indirect part (122), while the indirect part comprises at least one allocation condition.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: May 31, 2022
    Assignees: KONINKLIJKE KPN N.V., IMEC VZW, UNIVERSITEIT GENT
    Inventors: Wouter Tavernier, Didier Colle
  • Patent number: 11339124
    Abstract: The present invention relates to 3-(benzylamino)-4-(cyclohexylamino)-N-(2-(piperazin-1-yl)ethyl)benzenesulfonamide derivatives and related ferrostatin-1 (Fer-1) analogues as cell death inhibitors by inhibition of ferroptosis and/or oxytosis for the treatment of stroke, myocardial infarction, diabetes, sepsis, the prevention of transplant rejection, neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, multiple sclerosis, Huntington's disease, dementia with Lewy bodies and Friedreich's ataxia. The present invention further relates to pharmaceutical compositions of these compounds and discloses methods for making the compounds and the corresponding intermediate.
    Type: Grant
    Filed: February 5, 2019
    Date of Patent: May 24, 2022
    Assignees: UNIVERSITEIT ANTWERPEN, VIB VZW, UNIVERSITEIT GENT
    Inventors: Peter Vandenabeele, Tom Vanden Berghe, Koen Augustyns, Sam Hofmans, Pieter Van Der Veken, Lars Devisscher
  • Patent number: 11342995
    Abstract: A communication system includes a base station, at least one remote radio head, and at least one channel. The base station has at least two digital modulators adapted for modulating a first and a second incoming radio signal to obtain a first and a second quantized signal, a multiplexer for interleaving the quantized signals, and a transmitter adapted for transmitting the resulting quantized signal over the channel to the remote radio head. The remote radio head includes a receiver adapted for capturing the quantized signal, a clock extraction module adapted for converting the signal from the receiver into a clock signal, a demultiplexer for splitting the quantized signal using the clock signal to obtain at least two quantized signals, and a filter adapted for removing quantization noise from the quantized signal from the receiver or the demultiplexer.
    Type: Grant
    Filed: October 8, 2019
    Date of Patent: May 24, 2022
    Assignees: UNIVERSITEIT GENT, IMEC VZW
    Inventors: Guy Torfs, Piet Wambacq
  • Patent number: 11336236
    Abstract: A transimpedance amplifier is provided for converting a current between its two input terminals to a voltage over its two output terminals comprising a high-speed level shifter configured for creating a difference in input DC voltage and for being transparent for alternating voltages, an input biasing network configured for reverse biasing a photodiode connected to at least one of the input terminals and transparent for a feedback signal from the feedback network which is differentially and DC-coupled with the output terminals of the voltage amplifier and outputs of the feedback network are differentially and DC-coupled with the input biasing network of which outputs are coupled with inputs of the level shifter which is differentially and DC-coupled with input terminals of the voltage amplifier.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: May 17, 2022
    Assignees: UNIVERSITEIT GENT, IMEC VZW
    Inventors: Joris Lambrecht, Hannes Ramon, Bart Moeneclaey, Xin Yin
  • Patent number: 11336337
    Abstract: A multi-user access node for receiving concurrent signals which are carrying redundant chip sequences at a baseband rate, the access node including: a plurality of antennas organized in an antenna configuration; a main transceiver comprising an analog receiver and an ADC for converting an incoming signal into a digital signal which comprises the incoming chip sequences; a switch for switching the transceiver between the plurality of antennas; a controller configured for: initializing the multi-user access node by switching the transceiver between the plurality of antennas to capture a spatial character of the different users based on unique initialization chip sequences from the different users, separating collided chip sequences transmitted by different users by switching the transceiver between the plurality of antennas according to a scrambling sequence and by using the spatial character in combination with the applied scrambling sequence.
    Type: Grant
    Filed: April 30, 2021
    Date of Patent: May 17, 2022
    Assignees: UNIVERSITEIT GENT, IMEC VZW
    Inventor: Xianjun Jiao
  • Patent number: 11332554
    Abstract: The invention entails the combination of basic catalysts, specifically guanidine-based catalysts, such as TBD, in conjunction with functionalized amines having a hydrogen bond donating or accepting functionality, to facilitate the accelerated transamidation of polymer compounds with non-activated ester side chains.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: May 17, 2022
    Assignee: Universiteit Gent
    Inventors: Richard Hoogenboom, Joachim Van Guyse
  • Patent number: 11298057
    Abstract: A spectroscopic laser sensor based on hybrid III-V/IV system-on-a-chip technology. The laser sensor is configured to either (i) be used with a fiber-optic probe connected to an intravenous/intra-arterial optical catheter for direct invasive blood analyte concentration level measurement or (ii) be used to measure blood analyte concentration level non-invasively through an optical interface attached, e.g., to the skin or fingernail bed of a human. The sensor includes a III-V gain-chip, e.g., an AlGaInAsSb/GaSb based gain-chip and a photonic integrated circuit, with laser wavelength filtering, laser wavelength tuning, laser wavelength monitoring, laser signal monitoring and signal output sections realized on a chip by combining IV-based semiconductor substrates and flip-chip AlGaInAsSb/GaSb based photodetectors and embedded electronics for signal processing.
    Type: Grant
    Filed: July 7, 2021
    Date of Patent: April 12, 2022
    Assignees: Brolis Sensor Technology, UAB, Universiteit Gent, IMEC VZW
    Inventors: Augustinas Vizbaras, Kristijonas Vizbaras, Ieva {hacek over (S)}imonytė, Günther Roelkens
  • Patent number: 11293138
    Abstract: The present invention provides a post-fabrication modification approach for the fabrication of colored and chromic materials and sensors using plasma surface modification to covalently bind the coloring agent to the substrate, thus avoiding leaching of the dye. Advantageously, in said methods, said coloring agent is a dye or pigment linked to a radical sensitive functional group, such as an alkenyl or alkynyl functional group, and is applied to the substrate prior to the gas plasma treatment. The methods envisaged herein are generic in nature, which allow the covalent immobilization of various dyes on different materials. The covalently coated materials after plasma surface modification, particularly the covalently coated chromic materials and sensors, can be used in many different applications, such as protective textile and wound dressing applications.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: April 5, 2022
    Assignee: UNIVERSITEIT GENT
    Inventors: Richard Hoogenboom, Gertjan Vancoillie
  • Patent number: 11293012
    Abstract: The present application relates to the field of glyco-engineering and, more specifically, to eukaryotic cells wherein both an endoglucosaminidase is present and made deficient in UDP-galactose 4-epimerase (GalE). Typically, a glycoprotein is also present in the cells. These cells can be used to deglycosylate or partly deglycosylate the (exogenous) glycoprotein, in particular, without the need for adding an extra enzyme. Methods are also provided for the application of these cells in protein production.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: April 5, 2022
    Assignees: VIB VZW, Universiteit Gent
    Inventors: Nico Callewaert, Leander Meuris, Francis Santens
  • Patent number: 11293872
    Abstract: A laser ablation probe comprises a tubular element adapted for conducting a carrier fluid in a substantially laminar flow. The tubular element comprises a fluid inlet and a fluid outlet arranged at opposite end portions of the tubular element for enabling the carrier fluid to flow through the tubular element. The tubular element further comprises a central portion having an aperture defined therein for admitting an aerosol generated by laser ablation from a material sample into the carrier fluid flow when this sample is positioned outside the tubular element at a distance in the range of 0 ?m to 100 ?m from the aperture.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: April 5, 2022
    Assignee: UNIVERSITEIT GENT
    Inventors: Frank Vanhaecke, Stijn Van Malderen
  • Patent number: 11248057
    Abstract: The present application relates, in part, to agents that bind CD20 and their use as therapeutic agents. The present application further relates to pharmaceutical compositions comprising the CD20 binding agents and their use in the treatment of various diseases.
    Type: Grant
    Filed: March 7, 2017
    Date of Patent: February 15, 2022
    Assignees: VIB VZW, Universiteit Gent
    Inventors: Jan Tavernier, Anje Cauwels, José Van Der Heyden
  • Patent number: 11249371
    Abstract: A dispersive optical phased array for two-dimensional scanning is disclosed herein. The array comprises antenna blocks positioned adjacent one another. The antenna blocks comprise a plurality of antennas positioned adjacent one another and a plurality of delay lines to couple a coherent source signal to each of the antennas within the block, each delay line having an optical path length. Each of the antenna blocks acts as a dispersive phased array. The antenna blocks are arranged such that the blocks form a larger phased array where the antennas between the blocks are in phase for a discrete set of wavelengths. All antennas over the dispersive phased array can experience the same phase difference such that the beams of the individual antenna blocks align with one of the diffraction orders of the array of blocks.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: February 15, 2022
    Assignees: IMEC vzw, Universiteit Gent
    Inventor: Wim Bogaerts
  • Patent number: 11242511
    Abstract: The disclosure relates to a cytoplasmic protein complex comprising: (a) a first recombinant fusion protein comprising a kinase, fused to a first interaction polypeptide; and (b) a second recombinant fusion protein comprising a domain comprising a reporter phosphorylation site, whereby the domain is fused to a second interaction polypeptide. The disclosure relates further to a method to detect compound-compound-interaction using the cytoplasmic protein complex, and to cells comprising such cytoplasmic protein complex.
    Type: Grant
    Filed: February 25, 2019
    Date of Patent: February 8, 2022
    Assignees: VIB VZW, Universiteit Gent
    Inventors: Jan Tavernier, Samuel Lievens