Abstract: The present invention relates to the field of sustainable agriculture. Specifically, the invention provides microbial compositions and methods useful for the production of crop plants. In particular, the compositions and methods disclosed herein are useful for enhancing plant growth and/or plant yield as well as for promoting cold and salt tolerance.

Abstract: A light sensing device includes: a light sensitive layer having a phosphor with two different types of lanthanides dopant ions, switching between a first state and a second state; one or more optical filters on top of the light sensitive layer. When the dopant ions are in the second state after exposure of the light sensitive layer to the second light energy, the light sensitive layer measures a first light intensity of light of the first light energy. When the dopant ions are in the first state after exposure of the light sensitive layer to the first light energy, the light sensitive layer measures a second light intensity of light of the second light energy.

Abstract: The disclosure includes a system for photoacoustic inspection of an object. The system includes a broadband emission source configured to generate an emission beam, a direction apparatus including at least one spectrum splitter configured to split the emission beam into at least a first and a second component, the direction apparatus being configured to sequentially direct the respective components to N respective locations on the object at N times to generate N respective acoustic waves within the object. The N respective locations and N times are such that the respective N acoustic waves at least semi-constructively interfere to generate a respective propagating acoustic wave within the object. The system also includes a vibration sensing system configured to detect said respective propagating acoustic waves at a respective detection location on the object.

Abstract: Polyoxazoline polymers, polymer combinations, and compositions comprising those polymers or combinations of polymers are disclosed. The invention further relates to the use of said polyoxazoline polymers, said combinations and compositions comprising such polymers and combinations for the sustained release of one or more active ingredients, in particular one or more active pharmaceutical ingredients. It further relates to the use of polyoxazoline polymers or polymer combinations as drug carrier.

Abstract: A filter includes cascaded building blocks, for filtering an incoming signal. Each building block has first and second delay elements. A first scaling device is between an input node of the first delay element and an output node of the second delay element, and a second scaling device is between an output node of the first delay element and an input node of the second delay element. The building block has a cross scaling device between the output nodes of the first delay element and of the second delay element, and/or between the input nodes of the first delay element and of the second delay element. The building block is configured such that, in operation, incoming signals at the input node and output node of the second delay element are summed together.

Abstract: The present invention provides means and methods for the production in eukaryotic cells of homogeneous forms of small glycan structures which carry terminal galactose residues. In addition, the invention provides glycan-conjugates based on specific coupling with galactose residues present on the recombinant glycoproteins.

Abstract: The invention relates to a method to deink and/or to delaminate plastic material, preferably to a method to deink and delaminate plastic material in a single step. The method comprises the step of contacting the plastic material with an amine or a composition comprising said amine, wherein the amine comprises a nitrogen atom having at least one hydrocarbon substituent comprising an acyclic or cyclic alkyl group. The total number of carbon atoms of all hydrocarbon substituents of the nitrogen atom is at least (5).

Abstract: The present invention relates to a modified cytokine of the TNF superfamily, with reduced activity to its receptor, wherein said modified cytokine is specifically delivered to target cells. Preferably, said modified cytokine is a single chain variant of the TNF superfamily, even more preferably, one or more of the chains can-y one or more mutations, resulting in a low affinity to the receptor, wherein said mutant cytokine is specifically delivered to target cells. The targeting is realized by fusion of the modified cytokine of the TNF superfamily to a targeting moiety, preferably an antibody or antibody-like molecule. The invention relates further to the use of such targeted modified cytokine of the TNF superfamily to treat diseases.

Abstract: The disclosure relates to the field of reducing malodor, which is due to bacterial conversion of molecules that are present in sweat. Indeed, the disclosure describes acids, which steer the microbiome by inhibiting the growth of specific malodor-producing bacteria and/or promoting the growth of bacteria known to be beneficial in relation to malodor. The acids of the disclosure can thus be used in deodorants, washing powders, clothing finishing agents or any method to reduce malodor. The disclosure thus relates to a topical composition or textile finisher for use as a prebiotic.

Abstract: The invention relates to an admixture for a cementitious material suitable to influence the rheological properties of the cementitious material. The admixture includes a compound having a backbone chain provided with at least one first functionality and at least one second functionality. The at least one first functionality is adapted to adsorb to the cement particles of the cementitious material. The at least one second functionality is adapted to respond to an external trigger signal of an electric field, a magnetic field or an electromagnetic field, thereby influencing the rheological properties of the cementitious material. The rheological properties are influenced by influencing the interaction of the at least one first functionality with the cement particles and/or by influencing the interparticle interaction between the cement particles. The invention further relates to a cementitious material including such admixture.

Abstract: The present invention relates to solution electrospun fibers comprising a ingredient in an amorphous form, compositions and their manufacturing process thereof. More specifically, the present invention relates to solution electrospun fibers and a compositions comprising at least one of said fibers, said fiber obtained by solution electrospinning a ingredient with a polymer.

Abstract: The present invention provides a lipid nanoparticle comprising a fentanyl hapten, and a T helper peptide and/or an adjuvant, wherein the fentanyl hapten is conjugated to the outer surface of the lipid nanoparticle, and wherein the T helper peptide and/or the adjuvant is/are encapsulated within the lipid nanoparticle. The invention further provides a pharmaceutical composition comprising the lipid nanoparticle and uses thereof for inducing an immune response against fentanyl and the prevention or treatment of a fentanyl abuse disorder or a fentanyl addiction or a fentanyl overdose in a subject. Further provided herein is a method for preparing the lipid nanoparticle of the invention.

Abstract: The present invention is in the field of auditory devices. In particular, the present invention provides a method for converting an auditory stimulus to a processed auditory output. The present invention also relates to uses of the method, auditory devices configured to perform the method, and computer programs configured to perform the method for converting an auditory stimulus to a processed auditory output.

Abstract: The invention relates to a hafnium (IV) oxide (HfO2) nanoparticle nanocrystal comprising or having a diameter equal or less than (?) 15 nm, stabilized by a plurality of dispersant molecules attached to its surface. The dispersant molecules comprise of a catechol or gallol surface adsorption moiety and an oligo (ethyleneglycol) moiety. The invention further relates to a composition of such nanoparticles in stable colloidal suspension at physiological pH, and the use of the composition in medical treatment and diagnostic applications, particularly to enhance radiotherapy and as an X ray contrast agent. In yet another aspect, the invention provides a method for manufacturing compositions and nanoparticles according to the invention.

Abstract: The present disclosure relates to a method of analyzing a biofluid of a subject for the presence of bacterial extracellular vesicles (EV), the method comprising the steps of a) extracting bacterial EV from the biofluid, b) analyzing the bacterial EV-extracted molecular patterns for the presence of a disease marker, wherein the disease marker is a disease-specific molecular pattern of the subject; and the subject comprising patients diagnosed with HIV, IBD or cancer or the subject receiving a treatment.

Abstract: The disclosure relates to the treatment of blindness due to age-related presbyopia, age-related macular degeneration (AMD), diabetic retinopathy (DR) and/or diabetic macular edema (DME) in a human or animal. Age-related presbyopia is the loss of accommodation in any individual more than 40-50 years old, currently treated by reading glasses. AMD is the most common cause of irreversible loss of sight in persons >65 years in the western world. At this time, no treatment is available for the dry form of AMD. The dry form of AMD is characterized by vision threatening Drüsen, which are (sub)retinal accumulations of advanced glycation end products (AGEs) and fluorophores. DR and DME are the most common cause of irreversible loss of sight in persons <65 years in the western world. Current therapies for age-related presbyopia, AMD, DR and DME are disappointing and do not prevent the evolution to vision impairment, atrophy or blindness.

Abstract: The present invention relates to a mutant plant Cinnamoyl-CoA Reductase (CCR) protein capable of restoring the yield penalty in plants with lignin traits such as ccr-related deficiencies and methods and uses thereof. More specifically, the invention relates to plants lacking functional wild type CCR protein but having a weak ccr allele resulting in lower lignin amounts and increased saccharification, further accompanied by plant growth restoration of the lignin modification-induced dwarfism.

Abstract: An overload clutch comprising an input flange and an output flange, said clutch being configured to transmit torque between the input flange and the output flange and to disengage the clutch when the torque exceeds a predetermined threshold, characterised in, that the clutch comprises one or more sensing means at least partially integrated in at least one of the input and output flanges, and that the one or more sensing means are adapted to jointly determine the torque applied to transmitted between the input flange and the output flange of the clutch and to detect the disengagement of the clutch. A device comprising the clutch, a gear unit connected to the input flange, and a motor connected to the gear unit, configured to provide torque to the input flange through the gear unit.

Abstract: The present invention relates to antibodies and antigen-binding fragments that bind specifically to amino peptidase N, fusion constructs and uses thereof, in particular for the targeted delivery of molecules. More specific, the invention provides methods for vaccination, in particular oral vaccination inducing both mucosal and systemic immune responses and methods for treating, reducing or preventing gastrointestinal diseases using said antibodies or fragments.

Abstract: An X-ray detection system is described having a solid-state detector module including a plurality of detector tiles at a first side thereof for directly detecting X-ray radiation. The detector module has a plurality of interstitial areas separating adjacent tiles of the detector module, and at least one actuator for inducing motion of the detector module to a plurality of detection positions along a trajectory with respect to a stationary reference frame while the detector module is operated in an exposure mode. The spatial extent of the trajectory in the stationary reference frame is at least as large as the largest interstitial area, and the detector module is adapted for acquiring a plurality of frames in the exposure mode at a frame acquisition rate at least a factor of 100 faster than the inverse of a predetermined exposure time for the exposure mode.