Abstract: The present invention is in the field of auditory devices. In particular, the present invention provides a method for converting an auditory stimulus to a processed auditory output. The present invention also relates to uses of the method, auditory devices configured to perform the method, and computer programs configured to perform the method for converting an auditory stimulus to a processed auditory output.

Abstract: The invention relates to a method for layer-by-layer deposition of concrete by providing extrudable concrete. A first flow comprising a binder material and water and a second flow comprising a carrier material, an additional component and water are mixed in a static mixer to form a third flow of extrudable concrete. The material of the second flow has a shorter initial setting time than the material of the first flow. The first flow has a first viscosity V1 and the second flow has a second viscosity V2 so that the ratio V1/V2 ranges between 1/40 and 40. The third flow has a viscosity larger than the viscosity of the first flow and the second flow and a yield stress larger than the yield stress of the first flow and the second flow. The material of the third flow has an initial setting time shorter than initial setting time of the first flow. The invention further relates to a system to extrude concrete, in particular for layer-by-layer deposition of concrete.

Abstract: A device for detecting points and/or regions of rotational electrophysiological activity in or on a heart comprises an input for receiving spatiotemporal electrophysiological data corresponding to a plurality of spatial locations in or on the heart, a time feature extractor for providing time values indicative of times of occurrence of a predetermined feature of a plurality of electric potential waveforms at the spatial location, a mapping unit for providing pairs of adjacent spatial locations; a directed graph generator for generating a directed graph comprising directed edges; a topological feature analyzer.

Abstract: The present invention is directed to an anti-adsorption solution for the analysis of peptides. Also a process for the preparation of such an anti-adsorption solution and the use of said anti-adsorption solution are described.

Abstract: The present invention relates to synthetic receptors for ionophoric compounds, such as ionophoric toxins. Hence, the invention provides synthetic molecules capable of binding different ionophoric compounds, thereby being suitable for use in the detection, isolation and detoxification of such ionophoric compounds. The present invention further provides the use of such synthetic receptors in human and veterinary medicine, such as in the diagnosis, prevention and/or treatment of disorders caused by such ionophoric compounds. Finally, the invention provides methods of preparing such synthetic receptors for ionophoric compounds.

Abstract: The invention relates to a composition comprising an epoxy-derived covalent adaptable network, preferably an epoxy vitrimer comprising at least one unit of formula (I) The invention further relates to a method for preparing a composition comprising an epoxy-derived covalent adaptable network by contacting at least one amine comprising primary, at least one vinylogous precursor comprising vinylogous precursor groups and at least one epoxide comprising epoxide groups whereby the number of amine groups, the number of vinylogous precursor groups and the number of epoxide groups is controlled.

Abstract: The present invention is in the field of hearing tests. In particular, the present invention relates to systems and methods for determining the integrity of Auditory Nerve Fibers (ANFs) and/or afferent Auditory Nerve Synapses (ANSs) and/or inner-hair cells (IHC) in a subject.

Abstract: The present invention relates to a method for recovering N, K, and P from liquid waste stream, preferably from a stream of urine, or from a stream comprising excreta (e.g. faeces, manure, digestate, fertilizer), or from (concentrated) wastewater, for example, municipal (e.g. sewage, septic) and/or industrial wastewater (e.g. food and feed industry, agriculture, mining, etc.); more preferably from urine, such as human or animal urine; most preferably from human urine.

Abstract: The invention relates to a cyclic method of producing a hydrogen rich and/or a carbon monoxide rich stream using different materials, a first solid material, a second solid material and a CO2 sorbent material. In a first step a first gas stream comprising steam and at least one reductant is brought in contact with the three materials resulting in a hydrogen rich outlet stream. In a second step, the captured CO2 from the first step is released and converted to CO to produce a CO rich outlet stream. The invention further relates to an installation for producing a hydrogen rich and/or carbon monoxide rich stream.

Abstract: The present invention relates to the field of biochemistry, more particularly to proteomics, more particularly to protein sequencing, even more particularly to single molecule peptide sequencing. The invention discloses methods for single molecule protein sequencing and/or amino acid identification using cleavage inducing agents which are not specific for one particular amino acid, cleave polypeptides step by step from the N-terminus onwards and provide information on the identity of the cleaved amino acids based on the reaction kinetics.

Abstract: The invention relates to a cyclic method for capturing and utilizing CO2 contained in a gas stream. The method uses three different materials, a first solid material, a second solid material and a CO2 sorbent material. In a first step a first gas stream comprising CO2 and at least one reductant is brought in contact with the three materials, resulting in an outlet stream comprising water. In a second step, the captured CO2 from the first step is released and converted to CO to produce a CO rich outlet stream. The invention further relates to an installation for capturing and utilizing CO2.

Abstract: The present invention relates to the field of non-viral vectors and pharmaceutical compositions comprising polypropyleneimine and a nucleic acid, and their use in human or veterinary medicine. More precisely, the present invention relates to pharmaceutical compositions comprising a polymer or co-polymer of polypropyleneimine for delivery or transfection of a nucleic acid, e.g. RNA. The pharmaceutical compositions described herein are particularly useful for (nucleic acid) vaccination, nucleic acid-based protein therapy, nucleic-acid based protein replacement therapy, gene editing, base editing, cell therapy, immunotherapy, stem cell therapy, regenerative medicine, gene silencing, nucleic acid inhibition or protein inhibition.

Abstract: A method and a system for recovering nitrogen, and optionally phosphorus and/or potassium, from a liquid waste stream, such as a stream of urine or manure, or human urine is described. The method comprises passing the waste stream through a multi-compartment electrodialysis bipolar membrane (EDBM) system.

Abstract: The disclosure relates to a mixture of bacteria belonging to at least six or seven different and specific bacterial species preferably for use in preventing or treating gastro-intestinal disorders. Preferably, the mixture of bacteria is grown together in a fermenter prior to administering the mixture to a subject in order to prevent or treat the disorder.

Abstract: A non-surgical treatment of cataract in a human or animal. The invention specifically relates to the administration of a deglycating enzyme and its cofactor(s), which results in the deglycation of the lens crystallins. The disclosure thus relates to a minimal invasive type of treatment of cataract, which is easier and cheaper compared to existing surgical methods.

Abstract: A method for requesting a plurality of chunks by a streaming client on the basis of a single request message is described, wherein said chunks are defined on the basis of a manifest file comprising chunk identifiers for determining at least one delivery node for delivering chunks defined by said chunk identifiers to said client, wherein said method comprises: determining on the basis of said manifest file a first request message for requesting a first plurality of chunks, said first request message comprising one or more first chunk template parameters and a first chunk template, preferably an URL chunk template, comprising one or more chunk template parameters fields; sending said first request message to a first network node, wherein said first network node is configured for determining a first plurality of chunk identifiers, preferably a first plurality of URLs, associated with said first plurality of chunks on the basis of said first chunk template and said one or more first chunk template parameters; and

Abstract: An object classification system for classifying objects is described. The system comprises an imaging region adapted for irradiating an object of interest, an arrayed detector, and a mixing unit configured for mixing the irradiation stemming from the object of interest by reflecting or scattering on average at least three times the irradiation after its interaction with the object of interest and prior to said detection.

Abstract: A device for bringing a target medium into contact with a carrier fluid comprises a chamber comprising a circumferential wall, a bottom wall and a top wall forming an enclosure for containing the target medium while contacting the carrier fluid, the chamber being substantially rotationally symmetric with respect to an axis of symmetry and adapted for remaining mechanically static in operation of the device. The device comprises a fluid inlet for injecting the carrier fluid into the chamber in a substantially tangential direction with respect to an inner surface of the circumferential wall, and an outlet. The device comprises a fluid distributor in the chamber for enabling the injected carrier fluid to pass through the distributor in a substantially inward radial direction, the distributor being substantially rotationally symmetric and adapted for rotating around the axis when driven by a transfer of momentum between the injected carrier fluid and the distributor.

Abstract: An electrical machine (1) comprising: a rotatable drive shaft having a rotational axis (15); a rotor assembly (2) connected to the drive shaft, the rotor assembly 2 arranged to generate a static rotor magnetic field; a primary stator assembly (4), comprising a plurality of stator coils (5a, 5b) arranged to generate a rotating stator magnetic field for interacting with the static rotor magnetic field of the rotor assembly (2) such as to rotate the rotor assembly (2) along the rotational axis (15), and a secondary stator assembly (7) arranged to generate a static stator magnetic field; wherein the electrical machine (1) comprises a magnetic torsion spring (9) formed by the interaction of the static stator magnetic field with the static rotor magnetic field.

Abstract: The present application relates to the field of glyco-engineering, more specifically to glyco-engineering of Fc-containing molecules, such as antibodies. It is shown herein that Fc-containing molecules with a specific glycosylation pattern have a considerably longer circulating half-life in vivo, without having an altered binding affinity for their respective antigen. This has therapeutic implications in reducing the frequency with which these molecules need to be administered, without affecting therapeutic efficacy. Also, cells are provided that can produce the Fc molecules with the desired glycosylation pattern.