Patents Assigned to University College Dublin
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Patent number: 11962467Abstract: An embodiment includes a method for use in managing a cluster comprising a plurality of computers, each computer comprising at least one hardware processor coupled to at least one memory. The method comprises a computer-implemented manager: collecting access pattern data for the plurality of computers; based at least in part on the access pattern data, determining that at least a first one of the plurality of computers is overutilized; and responsive to determining that the first computer is overutilized, moving stored data from the first computer to at least a second one of the plurality of computers.Type: GrantFiled: August 14, 2017Date of Patent: April 16, 2024Assignees: International Business Machines Corporation, UNIVERSITY COLLEGE DUBLINInventors: Hitham Ahmed Assem Aly Salama, Teodora Sandra Buda, Patrick J. O'Sullivan, Philip Perry, Lei Xu
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Patent number: 11911407Abstract: The present invention relates to therapies and therapeutic agents for use in the treatment of cardiomyopathies. In particular, the invention is concerned with, but not limited to therapies and therapeutic agents for use in the treatment of hypertrophic cardiomyopathy. Such therapeutic agents comprise hypomethylating agents.Type: GrantFiled: April 17, 2018Date of Patent: February 27, 2024Assignee: UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELANDInventors: Chris Watson, John Baugh, Mark Ledwidge, Ken McDonald
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Publication number: 20240057624Abstract: Protein agglomeration is inhibited in a protein-containing liquid, within an industrial processing plant, using a microwave resonance cavity having an inlet conduit and an outlet conduit. The liquid is transported into and out of the cavity, and while within the cavity, it is exposed to a microwave electromagnetic field. This field exposure reduces the tendency of proteins within the liquid to agglomerate, and inhibits coagulation or protein deposition for an extended period of time after leaving the cavity.Type: ApplicationFiled: December 17, 2021Publication date: February 22, 2024Applicant: UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELANDInventor: Niall ENGLISH
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Publication number: 20240002947Abstract: A method for predicting risk of recurrence of cancer in an individual with cancer, the method comprising a step of assaying a cancer sample from the individual for positive expression of at least two genes or proteins encoded by those genes selected from the group consisting of FOXM1, UHRF1, PTTG1, E2F1, MYBL2, HMGB2, ATAD2, E2F8, ZNF367 and TCF19, wherein positive expression of the at least two genes correlates with increased risk of recurrence of cancer compared with an individual who does not exhibit positive expression of the at least two genes or proteins encoded by those genes.Type: ApplicationFiled: December 15, 2022Publication date: January 4, 2024Applicants: The Provost, Fellows, Scholars and Other Members of Board of Trinity College Dublin, University College Dublin, National University of Ireland, DublinInventors: Adrian Bracken, Fiona Lanigan, William Gallagher
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Publication number: 20230399671Abstract: The present invention relates to a cell, wherein the cell is modified to: reduce O-GalNAc galactosylation activity in the cell by reduction of functional COSMC molecular chaperone in the cell and/or by reduction of functional T-synthase in the cell; and overexpress ?1,4-galactosyltransferase in the cell; and associated methods, kits and uses.Type: ApplicationFiled: August 10, 2021Publication date: December 14, 2023Applicant: University College Dublin, National University of IrelandInventors: Ioscani JIMENEZ DEL VAL, Itzcóatl Arturo GOMEZ AQUINO
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Publication number: 20230361579Abstract: Provided are an apparatus and system for directing power flow between multiple devices, the apparatus comprising: one or more inlet ports for connection to one or more devices; a plurality of outlet ports configured for supplying electrical power; and a computing device configured to route power from the one or more inlet ports to the outlet ports. The system comprises a plurality of the apparatus connected to each other.Type: ApplicationFiled: July 13, 2023Publication date: November 9, 2023Applicant: University College Dublin, National University of Ireland, DublinInventors: Robert SHORTEN, Julia O’CONNELL, Barry CARDIFF, Giovanni RUSSO, Pietro FERRARO, Paul CUFFE
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Publication number: 20230360162Abstract: Serious gaming for interrelated critical infrastructure (CI) resilience improvement includes receiving from a serious gaming participant a selection of an anomalous event for a geographic region for which a hierarchy of CI elements has been modeled, and a specified change in allocation of at least one resource in a corresponding one of the CI elements. A previously determined cascading impact upon the CI elements resulting from the anomalous event is then retrieved and compared to a hypothetical cascading impact produced by a simulation of the model with the specified change. A visualization of the comparison is transmitted to the serious gaming participant so as to show the result of the hypothetical change in resources upon the cascading impact of the event in the hierarchy of CI elements.Type: ApplicationFiled: May 4, 2022Publication date: November 9, 2023Applicants: University College Dublin, Nurogames GmbHInventors: Páraic James Carroll, Daniel Patrick McCrum, Yash Shekhawat
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Publication number: 20230334038Abstract: Multi jurisdictional data sharing includes ingesting data sharing regulations for respectively different political jurisdictions and parsing each of the regulations into a corpus of regulatory text with portions of the corpus having been normalized into different sets of uniform regulations for corresponding ones of the different political jurisdictions. Each of the uniform regulations for each of the political jurisdictions is then matched with one or more applicable data sharing rules and a reference for each of the data sharing rules can be written to a data sharing rules table in association with one or more of the political jurisdictions determined to have uniform regulations matched to the one or more data sharing rules. Consequently, data sharing requests can be restricted as between organizations of one or more implicated political jurisdictions according to each matched data sharing rule in the data sharing rules table that had been associated with the political jurisdictions.Type: ApplicationFiled: April 13, 2022Publication date: October 19, 2023Applicants: University College Dublin, National University of Ireland, Dublin, Inlecom Group BVBAInventors: Ibad Kureshi, Raymond James Genoe, Robert Michael Dowdall, Cormac James Doherty, Antonios Mygiakis
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Publication number: 20230334168Abstract: Embodiments of the present invention provide a method, system and computer program product for tiered data sharing privacy assurance in responding for requests to inspect investigative data. In an embodiment of the invention, a method for tiered data sharing privacy assurance in responding for requests to inspect investigative data includes receiving a request to access investigative data and applying a privacy test to the request to determine if the request is specific for an individual or generic to any individual. On condition that the privacy test is determined to be generic, the request may be denied. But otherwise, on condition the test is determined to be specific, a data sharing rule that defines a degree to which the investigative data is to be shared may be applied and the request responded to according to the defined degree.Type: ApplicationFiled: April 13, 2022Publication date: October 19, 2023Applicants: University College Dublin, National University of Ireland, Dublin, Inlecom Group BVBAInventors: Ibad Kureshi, Raymond James Genoe, Robert Michael Dowdall, Cormac James Doherty, Antonios Mygiakis
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Patent number: 11780174Abstract: A surface preparation method (200) for a composite material (104) having an original surface (110), the material (104) comprising fibres (104a) within a matrix (104b), comprises removing (204) a surface portion of the matrix (104b) by plasma ablation so as to reveal and activate (206) a new surface (120) with at least a portion of a plurality of the fibres (104a) exposed thereon, without creating a residual heat-affected zone.Type: GrantFiled: November 2, 2018Date of Patent: October 10, 2023Assignee: University College Dublin, National University of IrelandInventors: Denis Dowling, James N. Barry
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Patent number: 11749998Abstract: Provided are an apparatus and system for directing power flow between multiple devices, the apparatus comprising: one or more inlet ports for connection to one or more devices; a plurality of outlet ports configured for supplying electrical power; and a computing device configured to route power from the one or more inlet ports to the outlet ports. The system comprises a plurality of the apparatus connected to each other.Type: GrantFiled: November 29, 2018Date of Patent: September 5, 2023Assignee: UNIVERSITY COLLEGE DUBLIN , NATIONAL UNIVERSITY OF IRELANDInventors: Robert Shorten, Julia O'Connell, Barry Cardiff, Giovanni Russo, Pietro Ferraro, Paul Dermot Cuffe
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Patent number: 11707519Abstract: Processes for the preparation of phosphorylated heptose compounds are provided. Embodiments of the invention relate to the chemical synthesis of heptopyranose phosphate compounds. Also, embodiments of the invention relate to the use of compounds according to the invention in modulating an immune response in a subject.Type: GrantFiled: May 11, 2018Date of Patent: July 25, 2023Assignees: UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, NATIONAL RESEARCH COUNCIL OF CANADAInventors: Andrew Cox, Janelle Sauvageau, Stefan Oscarson, Lorenzo Guazzelli
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Publication number: 20230181607Abstract: Disclosed herein, inter alia, are methods of using thiosaccharide compounds for treating coronavirus infection.Type: ApplicationFiled: May 11, 2021Publication date: June 15, 2023Applicants: The University of the Regents of California, University College DublinInventors: John Vincent Fahy, Irina Gitlin, Wilfred Raymond, Stefan Oscarson
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Patent number: 11666734Abstract: A stabilisation system for securing a medical device such as a catheter to tissue, in particular skin, the stabilisation system comprising a main body having a first section and a second section displaceable relative to one another to translate the system between an undeployed state and a deployed state, each section including an array of microneedles extending from a tissue contacting surface of the body and which penetrate the skin in response to the above displacement, the stabilisation system further comprising a closure member displaceable between an open position exposing a retention zone on the body and a closed position at least partially occluding the retention zone, within which retention zone the catheter or other medical device may be captured.Type: GrantFiled: April 16, 2019Date of Patent: June 6, 2023Assignee: UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLINInventors: Nicky Bertollo, Seamus Morris, Eoin O'Cearbhaill
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Patent number: 11642076Abstract: An oral appliance (100) comprising a sensing arrangement (101) disposed in proximity to at least one part of a facial muscle complex of a user. A method of controlling the oral appliance (100) comprising sensing, with the sensing arrangement (101), the at least one part of the facial muscle complex being brought towards the sensing arrangement; and in response to sensing the at least one part of the facial muscle complex being brought towards the sensing arrangement (101), controlling the oral appliance (100) to perform an action. An external processing unit (200) is arranged to interact with the oral appliance (100) in response to the oral appliance (100) performing the action.Type: GrantFiled: March 21, 2018Date of Patent: May 9, 2023Assignee: UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLINInventors: Frank Dillon, Eoin O'Cearbhaill, Kevin Krieger
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Publication number: 20230046326Abstract: The present disclosure relates to a phase-locked loop (PLL) based on a charge-sharing locking technique, capable of both fractional-N and integer-N operation. The PLL comprises a voltage pre-setting stage; an oscillator: a shared capacitive load; and a switching network configured for selectively connecting the voltage pre-setting stage to the shared capacitive load during a voltage pre-setting stage for applying an expectant voltage to the capacitive load. The switching network is being further configured for selectively connecting the capacitive load to the oscillator during a charge-sharing locking stage for correcting a phase error in response to a difference between the expected voltage of the capacitor and the voltage of the oscillator. Frequency-tracking and waveform-learning stages are also provided for maintaining PVT (process, voltage, temperature) robustness and for suppressing fractional-N spur, respectively.Type: ApplicationFiled: January 14, 2021Publication date: February 16, 2023Applicant: UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELANDInventors: Yizhe HU, Teerachot SIRIBURANON, Robert Bodgan STASZEWSKI
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Publication number: 20230028696Abstract: The invention relates to a method of determining the likelihood of an individual transitioning to a first episode of psychosis (FEP), the method comprising determining the level of selected markers in a bodily fluid sample from the individual, wherein the increase or decrease in the markers is predictive of the individual transitioning to a first episode of psychosis (FEP). The invention also relates to a method of predicting the functional outcome for an individual following a first episode of psychosis (FEP), the method comprising determining the level of selected markers in a bodily fluid sample from the individual, wherein the increase or decrease in the markers is predictive of an increased risk of functional disability outcome for the individual.Type: ApplicationFiled: December 23, 2020Publication date: January 26, 2023Applicants: THE ROYAL COLLEGE OF SURGEONS IN IRELAND, UNIVERSITY COLLEGE DUBLINInventors: David COTTER, David MONGAN, Mary CANNON, Gerard CAGNEY
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Patent number: 11552645Abstract: The present invention provides a fractional-N frequency synthesizer comprising a divider controller comprising a multistage noise Shaping (MASH) digital delta-sigma modulator comprising L error feedback modulator (EFM) stages, wherein the jth EFM stage is configured to receive as an input the sum of the error of the preceding EFM stage and a high amplitude dither signal derived from the error of the kth EFM stage, where 1?j?k?L.Type: GrantFiled: June 16, 2021Date of Patent: January 10, 2023Assignee: University College DublinInventors: Dawei Mai, Michael Peter Kennedy
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Publication number: 20220338464Abstract: A lung perfusion solution comprises a base solution comprising a physiological mixture of electrolytes and buffers, 3.5-5.5% (w/v) a first macromolecule having a molecular weight of 40-100 KDa, and an amount of a second, high molecular weight, macromolecule sufficient to adjust the relative viscosity of the solution to 2.0-3.0.Type: ApplicationFiled: December 3, 2021Publication date: October 27, 2022Applicant: UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLINInventors: Paul MCLOUGHLIN, Simon COYLE ROWAN
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Patent number: 11477666Abstract: In one example embodiment, a method includes obtaining sets of input data and an objective, the sets of input data including values of wireless network communication parameters, generating sets of output data for the sets of input data in accordance with the objective, generating a mapping of the sets of input data to the sets of output data and training a network controller using the mapping.Type: GrantFiled: February 15, 2018Date of Patent: October 18, 2022Assignee: UNIVERSITY COLLEGE DUBLIN NATIONAL UNIVERSITY OF IRELAND, DUBLINInventors: Stepan Kucera, Holger Claussen, David Lynch, David Fagan, Michael Fenton, Michael O'Neill