Abstract: Embodiments for implementing intelligent classification of region of interest in an organism in a computing environment by a processor. Time series data of a contrast agent in one or more regions of interest captured from multispectral image streams may be collected. The one or more regions of interest may be classified into one of a plurality of classes by applying one or more perfusion models, representing spatio-temporal behavior of the contrast agent reflected by the time series data, and by using a machine learning operation.

Abstract: A seed coating composition comprising a mixture of a fungal root endophyte isolated from a root of the plant found in low-nutrient, drought-stressed or multiply-stressed conditions and a carrier medium for application of said composition to a target seed, wherein the endophyte is characterised in having a nuclear ribosomal internal transcribed spacer (nr ITS) with at least a 90% sequence identity to any one of SEQ ID NOs: 3 to 15.

Abstract: Embodiments for implementing intelligent risk detection and mitigation in a transport network by a processor. Data gathered from a plurality of data sources relating to an entity and a selected region of interest may be analyzed. Behavior of an entity, in relation to a risk event, may be learned and interpreted based on a plurality of identified contextual factors, geographical data, current data, historical data, a learned risk event model, or a combination thereof. One or more mitigation actions may be performed to mitigate risk of occurrence or a possible negative impact of the risk event caused at least in part by the behavior of the entity.

Abstract: Processes for the preparation of phosphorylated heptose compounds are provided. Embodiments of the invention relate to the chemical synthesis of heptopyranose phosphate compounds. Also, embodiments of the invention relate to the use of compounds according to the invention in modulating an immune response in a subject.

Abstract: Angiotensin (1-7) analogs are provided. The analogs contain one or more substitutions with non-natural amino acid cis-3-(aminomethyl)cyclobutanecarboxylic acid (ACCA). Also provided are methods of making such analogs and methods for using such analogs as therapeutic compositions to treat or prevent various diseases or conditions.

Abstract: A method for predicting risk of recurrence of cancer in an individual with cancer, the method comprising a step of assaying a cancer sample from the individual for positive expression of at least two genes or proteins encoded by those genes selected from the group consisting of FOXM1, UHRF1, PTTG1, E2F1, MYBL2, HMGB2, ATAD2, E2F8, ZNF367 and TCF19, wherein positive expression of the at least two genes correlates with increased risk of recurrence of cancer compared with an individual who does not exhibit positive expression of the at least two genes or proteins encoded by those genes.

Abstract: A novel and useful time mode analog to digital converter (ADC) that employs injection locking to overcome the nonlinearities of the voltage controlled oscillator (VCO). The oscillator's frequency is modulated using injection locking rather than varying its supply voltage. The oscillator is injection locked with a vector modulated signal, the frequency of which is derived from the oscillator itself. The output of the oscillator is modulated by the input voltage Vin(t). The output of the modulator is at the same frequency as the oscillator with an envelope (i.e. amplitude) determined by Vin(t). This signal is injected back into the oscillator at one or more points. The frequency of the oscillator ?out(t) changes in order to satisfy the Barkhausen criteria for oscillation. Alternatively, each stage of a ring oscillator (RO) incorporates its own mixer (i.e.

Abstract: In an approach for determining the illumination necessary along a vehicle's planned trajectory, a processor receives information relevant to the trajectory of a vehicle. A processor estimates the position of the vehicle at the particular time on the trajectory of the vehicle, using the data from the sensors. A processor estimates an illumination of the trajectory of the vehicle, using the model of the illumination of the road network and the data from the sensors, wherein a threshold is employed. A processor determines the threshold is exceeded. A processor changes a setting of the at least one headlight on the vehicle. A processor determines the threshold is exceeded. A processor alerts the user of the vehicle when adjustments to the at least one headlight that are necessary to illuminate the trajectory of the vehicle exceed physical limitations of the at least one headlight.

Abstract: A method for predicting risk of recurrence of cancer in an individual with cancer, the method comprising a step of assaying a cancer sample from the individual for positive expression of at least two genes or proteins encoded by those genes selected from the group consisting of FOXM1, UHRF1, PTTG1, E2F1, MYBL2, HMGB2, ATAD2, E2F8, ZNF367 and TCF19, wherein positive expression of the at least two genes correlates with increased risk of recurrence of cancer compared with an individual who does not exhibit positive expression of the at least two genes or proteins encoded by those genes.

Abstract: A role of sharing broker can be activated on a first mobile device, the role of sharing broker brokering sharing of network resources of at least a first network among a plurality of other mobile devices. Data usage by the first mobile device on at least the first network can be monitored. Responsive to the data usage by the first mobile device on at least the first network exceeding a threshold value, an amount of data usage on at least the first network being shared by the first mobile device among the plurality of other mobile devices can be adjusted.

Abstract: There are provided, inter alia, methods for decreasing mucus elasticity or decreasing mucus viscosity in a subject in need thereof, the methods including administering to the subject an effective amount of a thiosaccharide mucolytic agent, and compounds and pharmaceutical compositions useful for the methods.

Abstract: In an approach for determining the illumination necessary along a vehicle's planned trajectory, a processor receives information relevant to the trajectory of a vehicle. A processor estimates the position of the vehicle at the particular time on the trajectory of the vehicle, using the data from the sensors. A processor estimates an illumination of the trajectory of the vehicle, using the model of the illumination of the road network and the data from the sensors, wherein a threshold is employed. A processor determines the threshold is exceeded. A processor changes a setting of the at least one headlight on the vehicle. A processor determines the threshold is exceeded. A processor alerts the user of the vehicle when adjustments to the at least one headlight that are necessary to illuminate the trajectory of the vehicle exceed physical limitations of the at least one headlight.

Abstract: A method for detecting an analyte in a sample, the method comprising contacting the analyte in a sample with nanoparticles comprising a capture probe for capturing said analyte, the capture probe being configured to act as a center for controlled aggregation of nanoparticles with said analyte to form an aggregate of predefined form, detecting the analyte by detecting the shape and/or size of the aggregate is provided. Also provided are nanoparticles comprising a capture probe for capturing an analyte, wherein the capture probe is configured to act as a center for controlled aggregation of nanoparticles with the analyte to form an aggregate of particular detectable size and/or shape, and an assay.

Abstract: Embodiments for data replication in a distributed file system environment by a processor. Data replication of one or more files that are more frequently used as compared to other files in a plurality of files may be increased according to hot data detected from one or more queries to a distributed file system.

Abstract: A first mobile device determines a second mobile device losing connectivity to a second network or a communication link between the second mobile device and the second network degrading below a threshold value, the second mobile device assigned a role of sharing broker that brokers sharing of network resources of at least a first network among a plurality of other mobile devices via the second network, the first mobile device and the plurality of other mobile devices participating in a sharing group. Responsive to the determination, the role of sharing broker is activated on the first mobile device.

Abstract: A novel and useful time mode analog to digital converter (ADC) that employs injection locking to overcome the non-linearities of the voltage controlled oscillator (VCO). The oscillator's frequency is modulated using injection locking rather than varying its supply voltage. The oscillator is injection locked with a vector modulated signal, the frequency of which is derived from the oscillator itself. The output of the oscillator is modulated by the input voltage Vin(t). The output of the modulator is at the same frequency as the oscillator with an envelope (i.e. amplitude) determined by Vin(t). This signal is injected back into the oscillator at one or more points. The frequency of the oscillator ?out(t) changes in order to satisfy the Barkhausen criteria for oscillation. Alternatively, each stage of a ring oscillator (RO) incorporates its own mixer (i.e.

Abstract: There is provided a method of aggregating a plurality of beads in a magnetic bead aggregation assay for subsequent analysis comprising: —providing magnetic beads comprising a capture probe for binding with said target analyte; —reacting the magnetic beads with the sample including a target analyte in a reaction chamber aggregating the magnetic beads in the presence of a magnetic field with the target analyte to allow formation of magnetic bead aggregates having physical properties detectable to enable characterization of the aggregates on an aggregate by aggregate basis using a detector to measure the physical properties of the aggregates. Further provided are a method and system for detecting analytes in a sample by characterizing the magnetic bead aggregates on an aggregate by aggregate basis by measuring physical properties of the aggregates.

Abstract: Embodiments for testing embedded systems and their applications in an Internet of Things (IoT) environment by a processor, denoted as a Hardware-in-the-Loop as a Service (HiLaaS). In a simulated environment, one or more simulated entities and one or more real entities in a networked system may be tested in real-time according to received control parameters, for a price. The price is estimated by the system, based on other parameters, and offered to the user to accept or reject. Alternatively, the user may specify the price, the system estimates control parameters, and the user can accept or reject the control parameters. One or more properties of the one or more entities, the network system, or combination thereof may be estimated based on the testing of the one or more simulated entities, when the price and control parameters are accepted.

Abstract: A sleep monitoring system includes an ECG device and a respiration inductance plethysmogram which monitor cardiac activity and physical respiration respectively and feed representative signals to a digital data processor. Operations process the beat interval data, while in a second thread, operations independently process the amplitude modulation of the ECG data caused by the respiratory motion of the subject. The inductance plethysmogram device provides an input to the processor which represents respiration as directly monitored independently of the ECG. Operations process this direct respiration data independently and in parallel, in a third thread. All extracted features are fed to a classifier which in step combines selected combinations of features to make decisions in real time.

Abstract: A novel and useful mm-wave frequency generation system is disclosed that takes advantage of injection locking techniques to generate an output oscillator signal with improved phase noise (PN) performance and power efficiency. Low frequency and high frequency DCOs as well as a pulse generator make up the oscillator system. A fundamental low frequency (e.g., 30 GHz) signal and its sufficiently strong higher (e.g., fifth) harmonic (e.g., 150 GHz) are generated simultaneously in a single oscillator system. The second high frequency DCO having normally poor phase noise is injected locked to the first low frequency DCO having good phase noise. Due to injection locking, the high frequency output signal generated by the second DCO exhibits good phase noise since the phase noise of the second DCO tracks that of the first DCO.