Abstract: At least one embodiment of the invention provides a photonic subsystem for integrating onto a photonic platform. The subsystem comprises a laser source and a plurality of optical components for focusing and directing a laser beam emitted from the laser source into a photonic platform. The laser source and plurality of optical components are mounted to a substrate and encapsulated.

Abstract: A seed coating composition comprising a mixture of a fungal root endophyte isolated from a root of the plant found in low-nutrient, drought-stressed or multiply-stressed conditions and a carrier medium for application of said composition to a target seed, wherein the endophyte is characterised in having a nuclear ribosomal internal transcribed spacer (nr ITS) with at least a 90% sequence identity to any one of SEQ ID NOs: 3 to 15.

Abstract: A delayed release coating includes a mixture of a first material selected from starch; amylose; amylopectin; chitosan; chondroitin sulfate; cyclodextrin; dextran; pullulan; carrageenan; scleroglucan; chitin; curdulan and levan, and a second material which has a pH threshold at about pH 5 or above. The delayed release coating is used to target release of a drug from a core to the intestine, particularly the colon.

Abstract: Aspects of the subject disclosure may include, for example, a method in which a processing system identifies a plurality of performance indicators comprising device performance indicators for a plurality of communication devices on a cellular network and network performance indicators for the cellular network. The method also includes obtaining historical data regarding the plurality of performance indicators for each of a series of time points during a past time period; the historical data for each of the plurality of performance indicators form an array of values for that performance indicator. The method further includes generating from each array a set of inputs to an algorithm for predicting a throughput of the cellular network during a future time period; the set of inputs comprises quantiles of the array, and the algorithm comprises a machine learning algorithm. Other embodiments are disclosed.

Abstract: A delayed release drug formulation includes a core and a coating. The coating includes a mixture of a first material selected from starch; amylose; amylopectin; chitosan; chondroitin sulfate; cyclodextrin; dextran; pullulan; carrageenan; scleroglucan; chitin; curdulan and levan, and a second material which has a pH threshold at about pH 5 or above. The delayed release drug formulation is used to target release of a drug from a core to the intestine, particularly the colon.

Abstract: Microwave resonance cavities and associated methods and apparatus are described. In one example, a cavity (100) comprises a first and a second input port (102, 104) for inputting microwave radiation at a first and a second frequency respectively. The microwave radiation at the first frequency may be to excite a sample in the cavity whereas the microwave radiation at the second frequency may be to interrogate a sample in the cavity for analysis. The cavity has dimensions such that it resonates at both the first and the second frequency.

Abstract: Methods and apparatus for analysis of nano-objects using wide-field bright field transmission techniques are described. Such methods may comprise acquiring a plurality of images of a sample (124) comprising a plurality of nano-objects using bright field illumination via a continuously variable spectral filter (114), and identifying a nano-object within the sample in the plurality of images, wherein the position of the nano-object changes between images. Using data extracted from the plurality of images, an extinction cross-section of the identified nano-object may be quantitatively determined.

Abstract: The present invention provides a method for performing high dynamic range optical image detection of a scene comprising: imaging incident light from a scene onto an object plane; determining the locations of those pixels in the object plane of higher brightness; detecting the optical irradiance values of those pixels of higher brightness to produce a first detected image; detecting the optical irradiance values of those pixels of lower brightness to produce a second detected image; and generating a high dynamic range optical irradiance map of the scene by combining the first detected image and the second detected image into a single image.

Abstract: Aspects of the subject disclosure may include, for example, a method in which a processing system identifies a plurality of performance indicators comprising device performance indicators for a plurality of communication devices on a cellular network and network performance indicators for the cellular network. The method also includes obtaining historical data regarding the plurality of performance indicators for each of a series of time points during a past time period; the historical data for each of the plurality of performance indicators form an array of values for that performance indicator. The method further includes generating from each array a set of inputs to an algorithm for predicting a throughput of the cellular network during a future time period; the set of inputs comprises quantiles of the array, and the algorithm comprises a machine learning algorithm. Other embodiments are disclosed.

Abstract: The present invention relates to the therapeutic uses of compositions containing antibody molecules and functional fragments thereof e.g antibody molecules and functional fragments capable of binding to tumor necrosis factor alpha (TNF?), in the topical treatment of inflammatory bowel diseases, including Crohn's disease and ulcerative colitis.

Abstract: A delayed release coating comprising a mixture of a first material selected from starch; amylose; amylopectin; chitosan; chondroitin sulfate; cyclodextrin; dextran; pullulan; carrageenan; scleroglucan; chitin; curdulan and levan, and a second material which has a pH threshold at about pH 5 or above, is used to target release of a drug from a core to the intestine, particularly the colon.

Abstract: The present invention discloses a method and system of providing a real time audification of neonatal EEG signals. The method comprises the steps of: receiving preprocessed neonatal EEG signals; changing a characteristic of the preprocessed signals in a phase vocoder; resampling the output signals from the vocoder to a predetermined audio frequency range; converting the resampled signals into stereo signals; and selecting a plurality of channels from the stereo signals as the output audio signals.

Abstract: A tunnel field effect transistor (100) comprises a source region (102), a drain region (104), and a channel region (106) formed of a single material, in particular a half-metal. The channel extends between the source region and the drain region. The channel region (106) and the drain region (104) are smaller than a threshold size in a first dimension. The threshold size is the size required for the material to exhibit sufficient quantum confinement such that a non-zero band gap results and the material becomes a semiconductor. The source region (102) is larger than this threshold size in the first dimension and is thus metallic.

Abstract: There is provided a method for distinguishing between sepsis and systemic inflammatory response syndrome (SIRS) in a patient, comprising: (i) determining the amount of one or more biomarker for sepsis, and one or more biomarker for SIRS in a sample obtained from a patient, wherein the one or more biomarker for sepsis is selected from the group consisting of: ITGB3, ITGA2B, MYL9, LCN2, TREML1, LCN15, CMTMS, PPBP, and PF4; and the one or more biomarker for SIRS is selected from the group consisting of: PLA2G7, ARHGEF10L, MYCL, TGFBI, and GPR124, (ii) comparing the amount of the one or more biomarker for sepsis determined in said sample in (i) to a corresponding reference value representative of a healthy individual, (iii) comparing the amount of the one or more biomarker for SIRS determined in said sample in (i) to a corresponding reference value representative of a healthy individual; wherein the patient is diagnosed as having sepsis, when an increase is observed in the one or more biomarker for sepsis, and no

Abstract: A novel and useful time mode analog to digital converter (ADC) that employs injection locking to overcome the nonlinearities of the voltage controlled oscillator (VCO). The oscillator's frequency is modulated using injection locking rather than varying its supply voltage. The oscillator is injection locked with a vector modulated signal, the frequency of which is derived from the oscillator itself. The output of the oscillator is modulated by the input voltage Vin(t). The output of the modulator is at the same frequency as the oscillator with an envelope (i.e. amplitude) determined by Vin(t). This signal is injected back into the oscillator at one or more points. The frequency of the oscillator ?out(t) changes in order to satisfy the Barkhausen criteria for oscillation. Alternatively, each stage of a ring oscillator (RO) incorporates its own mixer (i.e.

Abstract: Aspects of the subject disclosure may include, for example, a method in which a processing system identifies a plurality of performance indicators comprising device performance indicators for a plurality of communication devices on a cellular network and network performance indicators for the cellular network. The method also includes obtaining historical data regarding the plurality of performance indicators for each of a series of time points during a past time period; the historical data for each of the plurality of performance indicators form an array of values for that performance indicator. The method further includes generating from each array a set of inputs to an algorithm for predicting a throughput of the cellular network during a future time period; the set of inputs comprises quantiles of the array, and the algorithm comprises a machine learning algorithm. Other embodiments are disclosed.

Abstract: In an approach for determining the illumination necessary along a vehicle's planned trajectory, a processor receives information relevant to the trajectory of a vehicle. A processor estimates the position of the vehicle at the particular time on the trajectory of the vehicle, using the data from the sensors. A processor estimates an illumination of the trajectory of the vehicle, using the model of the illumination of the road network and the data from the sensors, wherein a threshold is employed. A processor determines the threshold is exceeded. A processor changes a setting of the at least one headlight on the vehicle. A processor determines the threshold is exceeded. A processor alerts the user of the vehicle when adjustments to the at least one headlight that are necessary to illuminate the trajectory of the vehicle exceed physical limitations of the at least one headlight.

Abstract: A method for the early prediction of risk of hypertensive disorders in pregnant women, including for example eclampsia, mild pre-eclampsia, chronic hypertension, EPH gestosis, gestational hypertension, superimposed pre-eclampsia, HELLP syndrome, or nephropathy.

Abstract: A nested mixed-radix DDSM can guarantee zero systematic frequency error when used as a divider controller in a fractional-N frequency synthesizer is described. This disclosure presents a nested cascaded mixed-radix DDSM architecture which can also guarantee zero systematic frequency error. In addition, the disclosure allows one to use higher order auxiliary modulators and shaped dither signal to eliminate feedthrough spurs completely. By increasing the number of levels in the cascade, the moduli of the individual modulator stages can be reduced, thereby increasing the speed of the synthesizer.

Abstract: An intravascular cell therapy device comprises a scaffold (2, 12) that is radially adjustable between a contracted orientation suitable for transluminal delivery to a vascular locus and an expanded orientation, and a biodegradable matrix provided on at least a portion of the scaffold that is suitable for seeding with cells and degrades in a vascular environment. The scaffold is configured to have a distal piercing tip (5) when in a deployed orientation. The scaffold comprises a plurality of sidewall panels (3, 13, 14) arranged around a longitudinal axis of the scaffold, and adjustable couplings (4) between the panels configured for adjustment between an expanded configuration and a contracted orientation, and in which each sidewall panel comprises a matrix suitable for seeding with cells.