Abstract: A diagnostic sensor device has a semiconductor chip having a distal end physically configured to fit into a power and data socket conforming to a non-proprietary standard, and having exposed pads for engagement with corresponding conductors of such a socket. At its proximal end the chip has at least one sensor for contact with an analyte. The device may be manufactured in a single integrated process to provide a wafer which is diced to provide the individual devices.

Abstract: Embodiments for implementing intelligent risk detection and mitigation in a transport network by a processor. Data gathered from a plurality of data sources relating to an entity and a selected region of interest may be analyzed. Behavior of an entity, in relation to a risk event, may be learned and interpreted based on a plurality of identified contextual factors, geographical data, current data, historical data, a learned risk event model, or a combination thereof. One or more mitigation actions may be performed to mitigate risk of occurrence or a possible negative impact of the risk event caused at least in part by the behavior of the entity.

Abstract: Methods and apparatus for analysis of nano-objects using wide-field bright field transmission techniques are described. Such methods may comprise acquiring a plurality of images of a sample (124) comprising a plurality of nano-objects using bright field illumination via a continuously variable spectral filter (114), and identifying a nano-object within the sample in the plurality of images, wherein the position of the nano-object changes between images. Using data extracted from the plurality of images, an extinction cross-section of the identified nano-object may be quantitatively determined.

Abstract: The present invention provides a method for performing high dynamic range optical image detection of a scene comprising: imaging incident light from a scene onto an object plane; determining the locations of those pixels in the object plane of higher brightness; detecting the optical irradiance values of those pixels of higher brightness to produce a first detected image; detecting the optical irradiance values of those pixels of lower brightness to produce a second detected image; and generating a high dynamic range optical irradiance map of the scene by combining the first detected image and the second detected image into a single image.

Abstract: Processes for the preparation of phosphorylated heptose compounds are provided. Embodiments of the invention relate to the chemical synthesis of heptopyranose phosphate compounds. Also, embodiments of the invention relate to the use of compounds according to the invention in modulating an immune response in a subject.

Abstract: Angiotensin (1-7) analogs are provided. The analogs contain one or more substitutions with non-natural amino acid cis-3-(aminomethyl)cyclobutanecarboxylic acid (ACCA). Also provided are methods of making such analogs and methods for using such analogs as therapeutic compositions to treat or prevent various diseases or conditions.

Abstract: A delayed release coating includes a mixture of a first material selected from starch; amylose; amylopectin; chitosan; chondroitin sulfate; cyclodextrin; dextran; pullulan; carrageenan; scleroglucan; chitin; curdulan and levan, and a second material which has a pH threshold at about pH 5 or above. The delayed release coating is used to target release of a drug from a core to the intestine, particularly the colon.

Abstract: Aspects of the subject disclosure may include, for example, a method in which a processing system identifies a plurality of performance indicators comprising device performance indicators for a plurality of communication devices on a cellular network and network performance indicators for the cellular network. The method also includes obtaining historical data regarding the plurality of performance indicators for each of a series of time points during a past time period; the historical data for each of the plurality of performance indicators form an array of values for that performance indicator. The method further includes generating from each array a set of inputs to an algorithm for predicting a throughput of the cellular network during a future time period; the set of inputs comprises quantiles of the array, and the algorithm comprises a machine learning algorithm. Other embodiments are disclosed.

Abstract: The present invention relates to the therapeutic uses of compositions containing antibody molecules and functional fragments thereof e.g antibody molecules and functional fragments capable of binding to tumor necrosis factor alpha (TNF?), in the topical treatment of inflammatory bowel diseases, including Crohn's disease and ulcerative colitis.

Abstract: A delayed release coating comprising a mixture of a first material selected from starch; amylose; amylopectin; chitosan; chondroitin sulfate; cyclodextrin; dextran; pullulan; carrageenan; scleroglucan; chitin; curdulan and levan, and a second material which has a pH threshold at about pH 5 or above, is used to target release of a drug from a core to the intestine, particularly the colon.

Abstract: The present invention discloses a method and system of providing a real time audification of neonatal EEG signals. The method comprises the steps of: receiving preprocessed neonatal EEG signals; changing a characteristic of the preprocessed signals in a phase vocoder; resampling the output signals from the vocoder to a predetermined audio frequency range; converting the resampled signals into stereo signals; and selecting a plurality of channels from the stereo signals as the output audio signals.

Abstract: A method for predicting risk of recurrence of cancer in an individual with cancer, the method comprising a step of assaying a cancer sample from the individual for positive expression of at least two genes or proteins encoded by those genes selected from the group consisting of FOXM1, UHRF1, PTTG1, E2F1, MYBL2, HMGB2, ATAD2, E2F8, ZNF367 and TCF19, wherein positive expression of the at least two genes correlates with increased risk of recurrence of cancer compared with an individual who does not exhibit positive expression of the at least two genes or proteins encoded by those genes.

Abstract: The invention relates to a SLED device emitting light from a substrate side, configured to suppress lasing, and comprising a reflective element (55) on a front surface of a substrate (22) configured to redirect an optical beam (light) onto a back surface of the substrate (22). In one embodiment the device can be used for making a compact RGB (red-green-blue) projector.

Abstract: A tunnel field effect transistor (100) comprises a source region (102), a drain region (104), and a channel region (106) formed of a single material, in particular a half-metal. The channel extends between the source region and the drain region. The channel region (106) and the drain region (104) are smaller than a threshold size in a first dimension. The threshold size is the size required for the material to exhibit sufficient quantum confinement such that a non-zero band gap results and the material becomes a semiconductor. The source region (102) is larger than this threshold size in the first dimension and is thus metallic.

Abstract: An isolated mammalian progenitor cell or its progeny, isolated from articular cartilage, is disclosed. Further is disclosed an equine progenitor cell isolated from the surface zone of equine articular cartilage tissue and uses thereof. Also disclosed are a method of tissue repair, a medicament, and a method of treating mammalian cartilage damage using such progenitor cells or progeny.

Abstract: According to an embodiment, a hearing aid system is disclosed. The system includes a speech processor communicatively coupled to a microphone. The speech processor is configured to process a microphone signal received at the speech processor for producing an electrical stimulation signal and an acoustic stimulation signal. The speech processor is also configured to generate a modified acoustic stimulation signal by modifying the acoustic stimulation signal at least for a part of a residual frequency range of a patient in dependence on effect of an implantable electrode array on mechanical properties of cochlea of the patient. The system also includes a first unit and a second unit.

Abstract: There is provided a method for distinguishing between sepsis and systemic inflammatory response syndrome (SIRS) in a patient, comprising: (i) determining the amount of one or more biomarker for sepsis, and one or more biomarker for SIRS in a sample obtained from a patient, wherein the one or more biomarker for sepsis is selected from the group consisting of: ITGB3, ITGA2B, MYL9, LCN2, TREML1, LCN15, CMTMS, PPBP, and PF4; and the one or more biomarker for SIRS is selected from the group consisting of: PLA2G7, ARHGEF10L, MYCL, TGFBI, and GPR124, (ii) comparing the amount of the one or more biomarker for sepsis determined in said sample in (i) to a corresponding reference value representative of a healthy individual, (iii) comparing the amount of the one or more biomarker for SIRS determined in said sample in (i) to a corresponding reference value representative of a healthy individual; wherein the patient is diagnosed as having sepsis, when an increase is observed in the one or more biomarker for sepsis, and no

Abstract: A novel and useful time mode analog to digital converter (ADC) that employs injection locking to overcome the nonlinearities of the voltage controlled oscillator (VCO). The oscillator's frequency is modulated using injection locking rather than varying its supply voltage. The oscillator is injection locked with a vector modulated signal, the frequency of which is derived from the oscillator itself. The output of the oscillator is modulated by the input voltage Vin(t). The output of the modulator is at the same frequency as the oscillator with an envelope (i.e. amplitude) determined by Vin(t). This signal is injected back into the oscillator at one or more points. The frequency of the oscillator ?out(t) changes in order to satisfy the Barkhausen criteria for oscillation. Alternatively, each stage of a ring oscillator (RO) incorporates its own mixer (i.e.

Abstract: Aspects of the subject disclosure may include, for example, a method in which a processing system identifies a plurality of performance indicators comprising device performance indicators for a plurality of communication devices on a cellular network and network performance indicators for the cellular network. The method also includes obtaining historical data regarding the plurality of performance indicators for each of a series of time points during a past time period; the historical data for each of the plurality of performance indicators form an array of values for that performance indicator. The method further includes generating from each array a set of inputs to an algorithm for predicting a throughput of the cellular network during a future time period; the set of inputs comprises quantiles of the array, and the algorithm comprises a machine learning algorithm. Other embodiments are disclosed.

Abstract: In an approach for determining the illumination necessary along a vehicle's planned trajectory, a processor receives information relevant to the trajectory of a vehicle. A processor estimates the position of the vehicle at the particular time on the trajectory of the vehicle, using the data from the sensors. A processor estimates an illumination of the trajectory of the vehicle, using the model of the illumination of the road network and the data from the sensors, wherein a threshold is employed. A processor determines the threshold is exceeded. A processor changes a setting of the at least one headlight on the vehicle. A processor determines the threshold is exceeded. A processor alerts the user of the vehicle when adjustments to the at least one headlight that are necessary to illuminate the trajectory of the vehicle exceed physical limitations of the at least one headlight.