Abstract: The invention relates to a block co-polymer film having different morphologies within said film, uses thereof and processes for its preparation.
Type:
Application
Filed:
July 29, 2019
Publication date:
April 14, 2022
Applicant:
Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.
Inventors:
Roy SHENHAR, Elisheva MICHMAN, Marcus MULLER
Abstract: A method of preparing a bacterial composition is disclosed. The method comprises: (a) in vitro co-culturing beneficial bacteria with biofilm-producing bacteria in a growth substrate under conditions that generate a biofilm which comprises the beneficial bacteria and the non-pathogenic bacteria; and (b) isolating the biofilm from the growth substrate.
Type:
Grant
Filed:
May 29, 2017
Date of Patent:
April 12, 2022
Assignees:
The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center), Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
Abstract: Provided are methods for extraction of various agents, e.g. active agent, from a plant source, specifically with the use of extraction formulations which are based on micellar liquid systems.
Type:
Application
Filed:
December 7, 2021
Publication date:
March 24, 2022
Applicant:
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
Abstract: Methods of generating organoids on multi-well plates are provided by depositing a polymeric solution comprising cells under conditions which result in a homogenous population of organoids, which can be used for high throughput analysis for drug screening and for determining treatment regimens of a drug.
Type:
Application
Filed:
August 22, 2021
Publication date:
February 10, 2022
Applicant:
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
Abstract: A guided tracheal intubation system using an autonomous modulated light source, outputting modulated illumination at a constant level, and externally applied to the subject's larynx region. An optical imaging system receives a video stream from within the subject's throat, including modulated illumination from the subject's trachea. A display control system performs signal processing on the modulated content of the images, and outputs frames of those images in which the intensity level of illumination from the trachea can be controlled without any need to change the illumination output from the modulated light source. The light source has no connection with the rest of the system, and need contain no more than a battery, a power supply circuit and a light source. It can therefore be of low cost and can be made disposable, such as in the form of an adhesive patch applied to the subject's neck.
Type:
Grant
Filed:
May 16, 2014
Date of Patent:
February 8, 2022
Assignees:
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Hadasit Medical Research Services and Development Ltd.
Abstract: Described herein are methods of enhancing formation and/or growth of an adventitious root in a plant and/or plant tissue, and/or for promoting grafting unification, enhancing fruit size and/or reducing flowering in a plant. The method comprises contacting at least a portion of the plant and/or plant tissue with a compound having Formula I: wherein X, Y and R1-R7 are as defined herein. Further described are compositions for enhancing formation and/or growth of an adventitious root in a plant and/or plant tissue, and/or for promoting grafting unification, enhancing fruit size and/or reducing flowering in a plant, comprising the abovementioned compound and a horticulturally acceptable carrier. Novel compounds having Formula I are also described herein.
Type:
Application
Filed:
October 18, 2021
Publication date:
February 3, 2022
Applicants:
The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization, Ramot at Tel-Aviv University Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
Inventors:
Einat SADOT, Roy WEINSTAIN, Joseph RIOV, Leor ESHED-WILLIAMS
Abstract: The inventors of the technology disclosed herein have developed triblock copolymers of lactide-containing polyesters and poly(ethylene glycol), PEG, having thermoresponsive properties.
Type:
Application
Filed:
November 14, 2019
Publication date:
January 27, 2022
Applicant:
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
Abstract: The present invention provides pyrazole derivatives, e.g., a compound of Formula (I), and their uses in methods of treating malignant disease and disorders and methods for treating inflammatory diseases and disorders.
Type:
Application
Filed:
July 26, 2021
Publication date:
January 20, 2022
Applicant:
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
Inventors:
Dansu Li, Irit Snir-Alkalay, Joseph P. Vacca, Yinon Ben-Neriah, Avanthika Venkatachalam
Abstract: An enriched population of connective tissue cells that are capable of anchorage-independent growth are provided. Compositions comprising those cells, as well as methods of producing those cells are also provided.
Type:
Application
Filed:
November 7, 2019
Publication date:
December 23, 2021
Applicant:
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
Abstract: The invention provides compositions comprising at least one cannabinoid compound, for use in the method of treating and preventing a disease, condition or symptom caused by, or associated with fungi, bacteria and microbes.
Type:
Application
Filed:
October 30, 2019
Publication date:
December 9, 2021
Applicant:
Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.
Abstract: A method for reducing renal tissue toxicity in a subject caused by a kidney damaging agent is disclosed. The method comprises administering to the subject: (i) a kidney damaging agent; and (ii) an inhibitor of glucose reabsorption.
Type:
Application
Filed:
August 22, 2021
Publication date:
December 9, 2021
Applicant:
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
Abstract: Provided is a novel photoinitiator in the form of a hybrid nanoparticle constructed of a semiconductor and metallic regions, and uses thereof.
Type:
Grant
Filed:
August 27, 2019
Date of Patent:
December 7, 2021
Assignee:
Yissum Research Development Company of the Hebrew
University of Jerusalem Ltd.
Abstract: An optically active structure and a display device are presented. The device utilized an optically active structure comprising liquid crystal material and a plurality of nanorods configured to emit light in one or more predetermined ranges in response to pumping light. Variation in orientation of the liquid crystal varies orientation of the nanorods and modulated light emission therefrom.
Type:
Grant
Filed:
September 20, 2015
Date of Patent:
November 16, 2021
Assignees:
Yissum Research Development Company Of The Hebrew
University of Jerusalem Ltd., Merck Patent GmbH
Inventors:
Uri Banin, Hagai Arbell, Bernhard Rieger, Ming-Chou Wu
Abstract: Small molecule inhibitors (SMIs) of the Prolactin receptor, pharmaceutical compositions of the SMIs, and methods for treating patients suffering from disorders characterized increased expression or excitation of the Prolactin receptor, including breast cancer, prostate cancer and nociceptive pain disorders such as migraine headache, by administering pharmaceutical compositions of SMIs are provided.
Type:
Grant
Filed:
September 8, 2017
Date of Patent:
November 9, 2021
Assignees:
University of Cincinnati, University of Texas System, The Hebrew University of Jerusalem
Inventors:
Nira Ben-Jonathan, Eric R. Hugo, Edward J. Merino, Abraham J. Domb, Armen N. Akopian
Abstract: Compositions that include certain phenyl substituted cyclohexenyl compounds are administered to a subject in a method for treating obesity or an associated disease or disorder or in a method of reducing food consumption or body weight.
Type:
Grant
Filed:
February 12, 2019
Date of Patent:
October 19, 2021
Assignee:
Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.
Abstract: Provided are methods for disrupting biofilms and/or preventing the formation of biofilms. Further provided are random-sequence peptide mixtures for use in disrupting bacterial biofilms. The random-sequence peptides include hydrophobic and/or cationic amino acids, and the ratio of the total hydrophobic and cationic amino acids in the mixture is predefined.
Type:
Grant
Filed:
February 2, 2017
Date of Patent:
August 31, 2021
Assignee:
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
Abstract: The present invention provides pyrazole pyrimidine derivatives which inhibit Casein kinase I (CKI) and/or Interleukin-1 receptor-associated kinase 1 (IRAKI) and methods of their manufacture, compositions comprising them and uses thereof in methods of treating malignant disease and disorders and methods for treating inflammatory diseases and disorders.
Type:
Application
Filed:
March 29, 2021
Publication date:
August 19, 2021
Applicant:
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
Inventors:
Yinon Ben-Neriah, Guy Brachya, Ido Burstain, Waleed Minzel, Irit Snir-Alkalay, Joseph P. Vacca, Dansu Li