Patents Assigned to University of Jerusalem
  • Publication number: 20220112342
    Abstract: The invention relates to a block co-polymer film having different morphologies within said film, uses thereof and processes for its preparation.
    Type: Application
    Filed: July 29, 2019
    Publication date: April 14, 2022
    Applicant: Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.
    Inventors: Roy SHENHAR, Elisheva MICHMAN, Marcus MULLER
  • Patent number: 11297868
    Abstract: A method of preparing a bacterial composition is disclosed. The method comprises: (a) in vitro co-culturing beneficial bacteria with biofilm-producing bacteria in a growth substrate under conditions that generate a biofilm which comprises the beneficial bacteria and the non-pathogenic bacteria; and (b) isolating the biofilm from the growth substrate.
    Type: Grant
    Filed: May 29, 2017
    Date of Patent: April 12, 2022
    Assignees: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center), Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Moshe Shemesh, Ram Reifen
  • Publication number: 20220088099
    Abstract: Provided are methods for extraction of various agents, e.g. active agent, from a plant source, specifically with the use of extraction formulations which are based on micellar liquid systems.
    Type: Application
    Filed: December 7, 2021
    Publication date: March 24, 2022
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Nissim GARTI, Sharon GARTI LEVI, Rotem EDRI
  • Publication number: 20220042975
    Abstract: Methods of generating organoids on multi-well plates are provided by depositing a polymeric solution comprising cells under conditions which result in a homogenous population of organoids, which can be used for high throughput analysis for drug screening and for determining treatment regimens of a drug.
    Type: Application
    Filed: August 22, 2021
    Publication date: February 10, 2022
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Yaakov NAHMIAS, Avner EHRLICH, Muneef AYYASH
  • Patent number: 11241147
    Abstract: A guided tracheal intubation system using an autonomous modulated light source, outputting modulated illumination at a constant level, and externally applied to the subject's larynx region. An optical imaging system receives a video stream from within the subject's throat, including modulated illumination from the subject's trachea. A display control system performs signal processing on the modulated content of the images, and outputs frames of those images in which the intensity level of illumination from the trachea can be controlled without any need to change the illumination output from the modulated light source. The light source has no connection with the rest of the system, and need contain no more than a battery, a power supply circuit and a light source. It can therefore be of low cost and can be made disposable, such as in the form of an adhesive patch applied to the subject's neck.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: February 8, 2022
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Hadasit Medical Research Services and Development Ltd.
    Inventors: Itai Hayut, Elchanan Fried, Yaakov Nahmias, Tommy Weiss-Sadan, Ariel Shrem
  • Publication number: 20220030866
    Abstract: Described herein are methods of enhancing formation and/or growth of an adventitious root in a plant and/or plant tissue, and/or for promoting grafting unification, enhancing fruit size and/or reducing flowering in a plant. The method comprises contacting at least a portion of the plant and/or plant tissue with a compound having Formula I: wherein X, Y and R1-R7 are as defined herein. Further described are compositions for enhancing formation and/or growth of an adventitious root in a plant and/or plant tissue, and/or for promoting grafting unification, enhancing fruit size and/or reducing flowering in a plant, comprising the abovementioned compound and a horticulturally acceptable carrier. Novel compounds having Formula I are also described herein.
    Type: Application
    Filed: October 18, 2021
    Publication date: February 3, 2022
    Applicants: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization, Ramot at Tel-Aviv University Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Einat SADOT, Roy WEINSTAIN, Joseph RIOV, Leor ESHED-WILLIAMS
  • Publication number: 20220023308
    Abstract: Provided is based on the discovery of novel agonists for PPAR-? which are proposed for use in medicine.
    Type: Application
    Filed: November 28, 2019
    Publication date: January 27, 2022
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Amiram GOLDBLUM, Jianwei CHE, Anwar RAYAN, Binyamin DAADOOSH, David MARCUS
  • Publication number: 20220025129
    Abstract: The inventors of the technology disclosed herein have developed triblock copolymers of lactide-containing polyesters and poly(ethylene glycol), PEG, having thermoresponsive properties.
    Type: Application
    Filed: November 14, 2019
    Publication date: January 27, 2022
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Abraham J. DOMB, Noam STEINMAN
  • Publication number: 20220017493
    Abstract: The present invention provides pyrazole derivatives, e.g., a compound of Formula (I), and their uses in methods of treating malignant disease and disorders and methods for treating inflammatory diseases and disorders.
    Type: Application
    Filed: July 26, 2021
    Publication date: January 20, 2022
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Dansu Li, Irit Snir-Alkalay, Joseph P. Vacca, Yinon Ben-Neriah, Avanthika Venkatachalam
  • Publication number: 20220008381
    Abstract: Provided are cannabinoid-loaded formulations, as well as processes for their preparation.
    Type: Application
    Filed: September 28, 2021
    Publication date: January 13, 2022
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Nissim GARTI, Sharon GARTI LEVI, Rotem EDRI
  • Publication number: 20210395690
    Abstract: An enriched population of connective tissue cells that are capable of anchorage-independent growth are provided. Compositions comprising those cells, as well as methods of producing those cells are also provided.
    Type: Application
    Filed: November 7, 2019
    Publication date: December 23, 2021
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Yaakov NAHMIAS, Merav Cohen
  • Publication number: 20210379010
    Abstract: The invention provides compositions comprising at least one cannabinoid compound, for use in the method of treating and preventing a disease, condition or symptom caused by, or associated with fungi, bacteria and microbes.
    Type: Application
    Filed: October 30, 2019
    Publication date: December 9, 2021
    Applicant: Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.
    Inventors: Doron STEINBERG, Raphael MECHOULAM
  • Publication number: 20210379094
    Abstract: A method for reducing renal tissue toxicity in a subject caused by a kidney damaging agent is disclosed. The method comprises administering to the subject: (i) a kidney damaging agent; and (ii) an inhibitor of glucose reabsorption.
    Type: Application
    Filed: August 22, 2021
    Publication date: December 9, 2021
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Yaakov NAHMIAS, Avner EHRLICH, Aaron COHEN
  • Patent number: 11193034
    Abstract: Provided is a novel photoinitiator in the form of a hybrid nanoparticle constructed of a semiconductor and metallic regions, and uses thereof.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: December 7, 2021
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Uri Banin, Hermona Soreq, Shlomo Magdassi, Nir Waiskopf, Yuval Ben-Shahar, Amol Ashok Pawar, Shira Halivni
  • Patent number: 11175536
    Abstract: An optically active structure and a display device are presented. The device utilized an optically active structure comprising liquid crystal material and a plurality of nanorods configured to emit light in one or more predetermined ranges in response to pumping light. Variation in orientation of the liquid crystal varies orientation of the nanorods and modulated light emission therefrom.
    Type: Grant
    Filed: September 20, 2015
    Date of Patent: November 16, 2021
    Assignees: Yissum Research Development Company Of The Hebrew University of Jerusalem Ltd., Merck Patent GmbH
    Inventors: Uri Banin, Hagai Arbell, Bernhard Rieger, Ming-Chou Wu
  • Patent number: 11168061
    Abstract: Small molecule inhibitors (SMIs) of the Prolactin receptor, pharmaceutical compositions of the SMIs, and methods for treating patients suffering from disorders characterized increased expression or excitation of the Prolactin receptor, including breast cancer, prostate cancer and nociceptive pain disorders such as migraine headache, by administering pharmaceutical compositions of SMIs are provided.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: November 9, 2021
    Assignees: University of Cincinnati, University of Texas System, The Hebrew University of Jerusalem
    Inventors: Nira Ben-Jonathan, Eric R. Hugo, Edward J. Merino, Abraham J. Domb, Armen N. Akopian
  • Patent number: 11149014
    Abstract: Compositions that include certain phenyl substituted cyclohexenyl compounds are administered to a subject in a method for treating obesity or an associated disease or disorder or in a method of reducing food consumption or body weight.
    Type: Grant
    Filed: February 12, 2019
    Date of Patent: October 19, 2021
    Assignee: Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.
    Inventors: Ruth Gallily, Raphael Mechoulam, Aviva Breuer
  • Publication number: 20210299157
    Abstract: The technology concerns topical formulations including nanocellulose materials for application on a skin or tissue of a subject.
    Type: Application
    Filed: August 6, 2019
    Publication date: September 30, 2021
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Oded SHOSEYOV, Tal BEN SHALOM
  • Patent number: 11103547
    Abstract: Provided are methods for disrupting biofilms and/or preventing the formation of biofilms. Further provided are random-sequence peptide mixtures for use in disrupting bacterial biofilms. The random-sequence peptides include hydrophobic and/or cationic amino acids, and the ratio of the total hydrophobic and cationic amino acids in the mixture is predefined.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: August 31, 2021
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventor: Zvi Hayouka
  • Publication number: 20210251992
    Abstract: The present invention provides pyrazole pyrimidine derivatives which inhibit Casein kinase I (CKI) and/or Interleukin-1 receptor-associated kinase 1 (IRAKI) and methods of their manufacture, compositions comprising them and uses thereof in methods of treating malignant disease and disorders and methods for treating inflammatory diseases and disorders.
    Type: Application
    Filed: March 29, 2021
    Publication date: August 19, 2021
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Yinon Ben-Neriah, Guy Brachya, Ido Burstain, Waleed Minzel, Irit Snir-Alkalay, Joseph P. Vacca, Dansu Li