Patents Assigned to University of Jerusalem
  • COMPOUNDS AND USES FOR THE TREATMENT AND PREVENTION OF DISEASES AND CONDITIONS ASSOCIATE WITH OR AGGREVATED BY IMPARED MITOPHAGY
    Publication number: 20210253511
    Abstract: The present invention provides compounds and methods for the treatment and prevention of diseases and conditions associate with or aggravated by impaired mitophagy.
    Type: Application
    Filed: March 13, 2019
    Publication date: August 19, 2021
    Applicant: Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.
    Inventors: Shmuel BEN-SASSON, Einav GROSS
  • Processes for the preparation of heterocyclic scaffolds from alpha enaminones
    Patent number: 11091438
    Abstract: The present invention provides processes for the preparation of diverse heterocyclic scaffolds from alpha-enaminone building bloc of formula (I).
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: August 17, 2021
    Assignee: Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.
    Inventor: Dmitry Tsvelikhovsky
  • High performance method and system for performing fault tolerant matrix multiplication
    Patent number: 11080131
    Abstract: A computer implemented method for performing fault tolerant numerical linear algebra computation task consisting of calculation steps that include at least classic or fast matrix multiplication, according to which, a controller splits the task among P processors, which operate in parallel. Additional processors are assigned according to execution and resources parameters, which are also used to select a slice-coded recovery algorithm or a posterior-recovery algorithm for executing the task. Pipelined-reduce operations are used to generate error correcting codes to protect the input blocks and outer products from faults. Upon detecting faults in one or more processors, if the slice-coded recovery algorithm has been selected, a slice-coded recovery algorithm is executed to recover lost input blocks and outer products that.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: August 3, 2021
    Assignee: Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.
    Inventors: Oded Schwartz, Noam Birnbaum
  • Self-processing synthesis of hybrid nanostructures
    Patent number: 11078073
    Abstract: Provided is a self-processing synthesis of hybrid nanostructures, novel nanostructures and uses thereof in the construction of electronic and optoelectronic devices.
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: August 3, 2021
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Roie Yerushalmi, Yossef Paltiel, Ori Pinchas-Hazut, Sharon Waichman, Amir Ziv, Shira Yochelis
  • HAPLOID HUMAN EMBRYONIC STEM CELL LINES AND SOMATIC CELL LINES AND METHODS OF MAKING THE SAME
    Publication number: 20210230539
    Abstract: Haploid human embryonic stem cells and cell lines, haploid multipotent human cells, and haploid differentiated human cells are provided. In addition, methods of making and using the haploid human cells are provided.
    Type: Application
    Filed: December 15, 2020
    Publication date: July 29, 2021
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Dietrich M. EGLI, Nissim BENVENISTY, Ido SAGI
  • Methods for treatment of Prader-Willi syndrome
    Patent number: 11058652
    Abstract: The present disclosure provides pharmaceutical compositions comprising a fatty acid amide of an amino acid as defined herein, such as oleoyl-?-methyl-serine, or a stereoisomer or salt thereof, for improving, as in increasing or preventing loss of, bone mineral density and/or treating osteoporosis in patients suffering from Prader-Willi syndrome; and their methods of use.
    Type: Grant
    Filed: April 13, 2017
    Date of Patent: July 13, 2021
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Raphael Mechoulam, Joseph Tam, Reem Smoum, Saja Baraghithy
  • TWO DIMENSIONAL ORGANO-METAL HALIDE PEROVSKITE NANORODS
    Publication number: 20210188884
    Abstract: Organometal halide perovskites are provided as nanoparticles for the construction of efficient light harvesters in photovoltaic solar cells. Further provided are methods of manufacturing the nanoparticles and uses thereof.
    Type: Application
    Filed: March 8, 2017
    Publication date: June 24, 2021
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Lioz ETGAR, Sigalit AHARON
  • INDOLINE DERIVATIVES, COMPOSITIONS COMPRISING THEM AND USES THEREOF
    Publication number: 20210169850
    Abstract: The present invention is directed to indoline derivatives and salts thereof, compositions comprising them and uses thereof for the treatment of diseases and disorders associated with at least one of oxidative stress, an immune response, release of NO and release of pro-inflammatory cytokine.
    Type: Application
    Filed: January 19, 2017
    Publication date: June 10, 2021
    Applicants: Yissum Research Development Company of The Hebrew University of Jerusalem Ltd., BAR ILAN UNIVERSITY
    Inventors: Marta WEINSTOCK-ROSIN, Abraham NUDELMAN, Shani ZEELI
  • Air treatment systems and methods
    Patent number: 11027236
    Abstract: An air treatment unit may include an air inlet to receive a flow of input air for treatment and a reaction reservoir configured to hold an aqueous air treatment solution. The air treatment unit may also include an air dispersing element flow connected with the air inlet, wherein the air dispersing element is configured to convert at least a portion of the flow of input air into a plurality of microbubbles for introduction into the aqueous air treatment solution, such that an amount of one or more target gas species contained within the plurality of microbubbles is reduced through reaction with the aqueous air treatment solution. The unit may include an air outlet configured to output treated air from the reaction reservoir.
    Type: Grant
    Filed: June 28, 2017
    Date of Patent: June 8, 2021
    Assignees: Airovation Technologies Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Marat Maayan, Uri Stoin, Yoel Sasson, Doron Weinfeld
  • DERIVATIVES OF TRICYCLIC SPIROLACTONES AND USES THEREOF IN TREATMENT AND MANAGEMENT OF PAIN
    Publication number: 20210163437
    Abstract: The present application relates to derivatives of tricyclic spirolactones compounds of formula (I) and compositions thereof and uses thereof in treatment and management of pain. Formula (I).
    Type: Application
    Filed: May 17, 2018
    Publication date: June 3, 2021
    Applicant: Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.
    Inventors: Dmitry TSVELIKHOVSKY, Avi PRIEL
  • Lipid-polymer conjugates, their preparation and uses thereof
    Patent number: 11013811
    Abstract: This invention provides low molecular weight lipid-GAG and phospholipids-GAG conjugates and methods of use thereof in suppressing, inhibiting, preventing, or treating a pathogenic effect on a cell, including, inter alia, infection with intracellular pathogens.
    Type: Grant
    Filed: October 27, 2014
    Date of Patent: May 25, 2021
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Saul Yedgar, Yuval Cohen, Joseph V. Bondi
  • PROCESS FOR FABRICATING CONDUCTIVE PATTERNS ON 3-DIMENSIONAL SURFACES BY HYDRO-PRINTING
    Publication number: 20210153345
    Abstract: Provided is a process for fabricating a conductive pattern on a three-dimensional (3D) object, involving hydroprinting a 2-dimensional (2D) conductive planar pattern on a 2D sacrificial substrate, and transferring the pattern to the 3D object.
    Type: Application
    Filed: March 8, 2018
    Publication date: May 20, 2021
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Shlomo MAGDASSI, Michael LAYANI, Gabriel SAADA
  • SYSTEM AND METHOD FOR USE IN FRET MICROSCOPY
    Publication number: 20210140889
    Abstract: A system and method are presented, for monitoring and/or imaging of a sample. The system comprises: a light unit configured for illuminating the sample in at least two different wavelength ranges; a collection unit configured for collecting a light emitted from the sample in at least a third wavelength range and directing said emitted light towards at least one detector; and an activation unit configured for providing activation signal to selectively activate at least a portion of fluorescent substance in the sample; and a processing circuitry configured for operating the light unit to determine a selected temporal illumination profile of said at least two different wavelength ranges and for operating the activation unit for controllable activation.
    Type: Application
    Filed: January 14, 2021
    Publication date: May 13, 2021
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Eilon SHERMAN, Shai TSIPSHTEIN
  • 3D POLYMERIZABLE CERAMIC INKS
    Publication number: 20210139720
    Abstract: Provided are formulations and processes for manufacturing 3D objects, the formulations being free of particulate materials and used in low temperature 3D printing processes.
    Type: Application
    Filed: January 19, 2021
    Publication date: May 13, 2021
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd
    Inventors: Shlomo MAGDASSI, Ido COOPERSTEIN, Efrat SHUKRUN
  • TOPICAL DELIVERY SYSTEMS FOR ACTIVE COMPOUNDS
    Publication number: 20210137829
    Abstract: Provided concerns viscous or gelled delivery systems based on oily nano-domains dispersed in a viscosified/gelled continuous aqueous phase, and suitable for prolonged and/or sustained topical delivery of various active compounds.
    Type: Application
    Filed: March 7, 2018
    Publication date: May 13, 2021
    Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Lyotropic Delivery Systems Ltd
    Inventors: Nissim GARTI, Sharon GARTI LEVI
  • DRUG DELIVERY SYSTEMS
    Publication number: 20210128534
    Abstract: A novel platform for manufacturing storage stable and effective drug delivery systems.
    Type: Application
    Filed: February 26, 2019
    Publication date: May 6, 2021
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Simon BENITA, Taher NASSAR, Leslie REBIBO, Amit BADIHI
  • Methods of modulating stomata conductance and plant expression constructs for executing same
    Patent number: 10975385
    Abstract: A method of regulating plant stomata conductance is provided. The method comprises modulating in the plant the level and/or activity of a type B hexokinase in a guard cell specific manner, thereby regulating plant conductance.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: April 13, 2021
    Assignees: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center), Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: David Granot, Gilor Kelly, Menachem Moshelion
  • Haploid human embryonic stem cell lines and somatic cell lines and methods of making the same
    Patent number: 10961503
    Abstract: Haploid human embryonic stem cells and cell lines, haploid multipotent human cells, and haploid differentiated human cells are provided. In addition, methods of making and using the haploid human cells are provided.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: March 30, 2021
    Assignees: New York Stem Cell Foundation, Inc., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Dietrich M. Egli, Nissim Benvenisty, Ido Sagi
  • Process for treating plastic waste
    Patent number: 10961368
    Abstract: Processes of treating plastic waste that include converting one or more plastic polymers into a liquid form either by dissolving in an organic solvent or by melting, and degrading the polymer(s) with the aid of alkali hydroxide and hydrogen peroxide are described. The processes can be performed in the presence of a phase transfer catalyst.
    Type: Grant
    Filed: January 3, 2017
    Date of Patent: March 30, 2021
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Yoel Sasson, Uri Stoin
  • NANOPARTICLES AND FORMULATIONS FOR PRINTING
    Publication number: 20210087302
    Abstract: A method for generating reactive species in a medium in which light irradiates the medium including a nanoparticle. A photoinitiator composed of semiconductor nanoparticles for photo-polymerization and 2D and 3D printing.
    Type: Application
    Filed: February 6, 2019
    Publication date: March 25, 2021
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Uri BANIN, Shlomo MAGDASSI, Nir WAISKOPF, Lior Efraim VERBITSKY