Abstract: A method for monitoring a fetal heart rate may include the steps of: acquiring fetal heart rate monitoring data; determining a fetal heart rate value by dividing the acquired fetal heart rate monitoring data by a predetermined time interval; and determining a fetal state by applying, to the determined fetal heartbeat value, a learned artificial intelligence algorithm using a learning database including the fetal heartbeat monitoring data pre-acquired in association with a plurality of fetuses.

Abstract: Disclosed are an oral fixation device for radiation therapy and an oral fixation method in treatment of a lip cancer. The oral fixation device for radiation therapy includes a first spacer including a first insert inserted between a first lip portion and a first gum portion, and a teeth support coupled to the first spacer at a side of the first spacer disposed inwardly of an oral cavity, wherein teeth or a gum of a patient is supported on the teeth support, wherein a first spacer has a specific thickness to maintain a specific spacing between the first lip portion and the first gum portion, wherein the first lip portion includes a treatment target portion to be subjected to the radiation therapy.

Abstract: A method for predicting brain disease state change is disclosed. The method includes acquiring test images obtained by capturing a portion of a human brain at a time interval, performing a pre-processing procedure of converting the test images into test voxels configured to be processed for image analysis, wherein a respective test voxel of the test voxels is composed of three-dimensional voxel units, mapping first and second test voxels selected from the test voxels acquired from a patient, with each other on a three-dimensional voxel unit, wherein the first test voxel is acquired at a first time-point and the second test voxel is acquired at a second time-point, generating a voxel-based data-set based on the mapped first and second test voxels, extracting a change in the test voxels using a deep neural network, and generating a state change probability model based on the change in the test voxels.

Abstract: A method for detecting disease using a manometry includes obtaining pressure values from each of the plurality of pressure sensors during a pre-set time, obtaining a three-dimensional pressure distribution showing the changes in the pressure values according to location and time by using the time, the pressure values, and locations in which the pressure sensors are disposed within the arbitrary location section, and calculating the volume integral value of the interest location which is predetermined in accordance with the disease, in the three-dimensional pressure distribution.

Abstract: A method for predicting a pulmonary disease includes acquiring a three-dimensional computed tomography (CT) image from two-dimensional CT images, each of which captures a respective body position of a first patient, dividing the three-dimensional CT image into a plurality of regions to obtain region-based three-dimensional CT images configured to be used for fractal analysis, calculating a region-based fractal dimension value indicating a fractal complexity of a respective region-based three-dimensional CT image among the generated region-based three-dimensional computed tomography images, adding additional information to the region-based fractal dimension value to generate high-dimensional data, and generating status information of the first patient based on the complexity of the generated high-dimensional data.

Abstract: The present invention relates to a method for lysing pathogen lysis and a method for extracting nucleic acid using zinc oxide nanostar, and the method for extracting nucleic acid using zinc oxide nanostar according to the present invention can extract nucleic acids by lysing cells of a pathogen without using a lysis buffer and can extract nucleic acid of high-purity and high-concentration by preventing nucleic acid degradation and fragmentation through various substances including salts contained in the lysis buffer at high concentration. In addition, the zinc oxide nanostar of the present invention (200 to 900 nm) has superior cell lysis capacity compared to the conventional zinc oxide nanoparticles (20 to 50 nm), thereby increasing the nucleic acid extraction efficiency and can extract at room temperature without a heating step to use as a field diagnostic method.

Abstract: Disclosed are a radiotherapy assistant apparatus for modulating a build-up region of a photon beam for a radiotherapy, a radiotherapy system including the radiotherapy assistant apparatus, and method for the radiotherapy system. The radiotherapy assistant apparatus for modulating a build-up region of a photon beam for a radiotherapy, including at least: a magnetic field generator that generates a magnetic field that has a direction perpendicular to a movement direction of the photon beam, the magnetic field generator is disposed on a movement route along which the photon beam moves toward a target portion of the radiotherapy; and a magnetic field intensity adjuster that adjusts an intensity of the magnetic field generated by the magnetic field generator. The magnetic field generator disperses secondary electrons that have particular energy levels equal to or lower than a preset value.

Abstract: A method for detecting disease using a manometry includes obtaining pressure values from each of the plurality of pressure sensors during a pre-set time, obtaining a three-dimensional pressure distribution showing the changes in the pressure values according to location and time by using the time, the pressure values, and locations in which the pressure sensors are disposed within the arbitrary location section, and calculating the volume integral value of the interest location which is predetermined in accordance with the disease, in the three-dimensional pressure distribution.

Abstract: Disclosed are an oral fixation device for radiation therapy and an oral fixation method in treatment of a lip cancer. The oral fixation device for radiation therapy includes a first spacer including a first insert inserted between a first lip portion and a first gum portion, and a teeth support coupled to the first spacer at a side of the first spacer disposed inwardly of an oral cavity, wherein teeth or a gum of a patient is supported on the teeth support, wherein a first spacer has a specific thickness to maintain a specific spacing between the first lip portion and the first gum portion, wherein the first lip portion includes a treatment target portion to be subjected to the radiation therapy.

Abstract: Disclosed are a method for designing dental prosthesis, an apparatus for the same, and a recording medium for recording the same. According to the method, sore spots on which a patient may feel pain due to wearing a dental prosthesis are predicted based on a sore spot distribution model which has been modeled with a plurality of data, and the dental prosthesis is digitally designed based on the predicted results. Accordingly, it is possible to improve the prediction accuracy of sore spots and rapidly design the prosthesis which is more appropriate for the patient.

Abstract: A method for diagnosing follicular thyroid carcinoma is described. The method measures protein expression levels of an aminoacyl-tRNA synthetase (ARS) or an aminoacyl-tRNA synthetase complex-interacting multifunctional protein (AIMP) in a sample, such as a thyroid tissue sample, from a subject suspected of having follicular thyroid carcinoma. The protein expression levels of ARS or AIMP are compared to the measured protein expression levels in a control.

Abstract: The present invention relates to a method for providing an ultrasonic image analysis and, more particularly, a method for providing information, which is helpful in diagnosing a disease of a fetus, by extracting a placenta part from an ultrasonic image and analyzing, by using a deep learning engine, a correlation among microscopic images for a placenta.

Abstract: Provided is a peptide for targeting gastric cancer, a composition for diagnosing radioresponsiveness-dependent gastric cancer using the peptide, and a drug delivery use of the peptide, wherein a functional peptide capable of targeting cancer has been discovered so as to implement personalized diagnosis and treatment for individual patients having cancer, consideration of problems occurring during treatment in which treatment cases of respective patients differ due to different therapeutic responses resulting from genetic differences in the individual patients.

Abstract: The present disclosure relates to a method, an apparatus and a computer program for noninvasively determining a cause of a blood pressure change. The method includes at least: obtaining maximum amplitudes of heart sounds; monitoring changes in the maximum amplitudes; estimating change amounts of indexes on a myocardial contractile force and on vascular resistance, based on increasing or decreasing of a blood pressure of the patient, and the changes in the maximum amplitudes; and determining the cause of the blood pressure change of the patient as an effect of at least one of alpha action, alpha blockage, beta action and beta blockage, based on results of the estimation of the first change amount of the first index, the second change amount of the second index and the third change amount of the third index.

Abstract: A stent for anastomosis of different kinds of organs includes a main body, and at least one fixing unit provided in the main body. At least a portion of the main body is inserted into one of different kinds of organs to be anastomosed with each other, and the rest of the main body is inserted into the other of the different kinds of organs. A distance between the different kinds of organs under the anastomosis is maintained by the fixing units.

Abstract: The present disclosure relates to an apparatus for closed reduction of a bone fracture. The apparatus includes at least: a pulling adaptor including: a handle configured to be gripped by an operator; an insertion rod that is extended from the handle in a longitudinal direction of the handle, and configured to be inserted into the bone fracture which is depressed in at least one area thereof; and a pulling lug that is bent and extended from an end of the insertion rod such that a longitudinal direction of the pulling lug is perpendicular to a longitudinal direction of the insertion rod or such that the pulling lug is inclined with respect to the insertion rod, the pulling lug being configured to be inserted into the at least one depressed area of the bone fracture, in order to pull the bone fracture.

Abstract: The present description relates to a frequency-based wake-up device and a sensor communication device using such the same. The present invention comprises: a RF signal to voltage converter for receiving a wireless signal including a first signal and a second signal and converting the frequency of the preamble to voltage to generate a driving voltage and provide the same; a decoder activated by the driving voltage and extracts ID information of the sensor communication device by decoding the second signal; and a signal processor that is activated by the driving voltage and compares the extracted ID information of the sensor communication device by the decoder with pre-stored ID information of a pre-determined sensor communication device and notifies of reception of a wake-up signal when the extracted ID information and the pre-stored ID information are the same.

Abstract: The present invention relates to method for simulating mandibular movements, device for the same and recording medium for recording the same. With the method for simulating mandible movements according to the present invention, it is possible to perform the simulation directly on the medical image of the patient and thus simulate the mandibular movements more closely to the actual situation. Therefore, the inaccurate mechanical approximation of the mandibular movement with the articulator according to the conventional art is overcome. In addition, according to the present invention, it is possible to simulate mandibular movements customized to the various states of the patient and specific clinical cases.

Abstract: Provided are a pharmaceutical composition including a Crepidiastrum denticulatum extract as an active ingredient; and a method for preventing or treating ischemia-reperfusion injury in a subject by using a food composition or the pharmaceutical composition.

Abstract: Disclosed is a method of monitoring consciousness, the method including sensing at least two brainwave signals, extracting respective phase signals from the sensed brainwave signals, calculating entropy based on a variety in a change in terms of a phase difference between the extracted phase signals, and assessing a state of consciousness based on the calculated entropy.