Abstract: The present disclosure a leak-proof lost-circulation control water-based drilling fluid composition and preparation method and use thereof.

Abstract: Provided herein, inter alia, are methods and compounds for inhibiting K-Ras and for treating cancer.

Abstract: The present invention provides a system and method for automation of the creation of a software application as a combination of microservices by extraction of discrete elements of software functionality from a monolithic architectures using dynamic and static analysis of code and non-code-related artefacts; forming them into microservices such that the software application is recreated as serverless hardware infrastructure while also validating the transformed code. In many cases, serverless microservices will significantly reduce the hardware requirement for software systems.

Abstract: The present invention relates to a composition for preventing, improving or treating muscle atrophy, which includes Gryllus bimaculatus, and more particularly, a Gryllus bimaculatus powder or Gryllus bimaculatus protein extract, as an active ingredient, and a method of preparing the same. The composition according to the present invention is effective in inhibiting the expression of muscle atrophy-associated key transcription factors, such as FoxO3 and MuRF-1, and is expected to be effectively used in muscle atrophy, various diseases caused thereby, muscle aging, undernourished patients, growing children and the elderly.

Abstract: An atomizing apparatus for film formation enabling high-quality thin film formation with suppressed particle adhesion, including: a raw-material container accommodating a raw-material solution; a cylindrical member connecting inside the raw-material container to an outer unit, and disposed so a lower end of the cylindrical member does not touch a liquid surface of the raw-material solution in the container; an ultrasound generator having at least one source emitting ultrasound; and a liquid tank where the ultrasound propagates the raw-material solution through a middle solution. The generation source is outside the liquid tank and has a center between a plane extending from an inner side wall of the raw-material container and a plane extending from an outer side wall of the cylindrical member. A center line of an ultrasound-emitting surface of the ultrasound generation source is designated as u, wherein the center line u does not intersect the cylindrical member side wall.

Abstract: In most buildings energy for space heating and cooling can be used to maintain the thermal comfort of the building's human occupants by maintaining the interior air temperature at a set point. If one could maintain the human occupant's thermal comfort while decreasing the heating or increasing the cooling set point, energy savings are possible. Many embodiments implement methods and systems of tunable emissivity surfaces in improving building efficiency. Several embodiment implement tuning the thermal emissivity of interior building surfaces at long-wave infrared wavelengths to maintain thermal comfort.

Abstract: Therapeutics and methods of treating COVID-19 in a patient in need thereof comprising administering a pharmaceutically effective dose of a therapeutic, wherein the therapeutic contains an ACE2 externalizer, and the ACE2 externalizer is one of diminazene, diminazene aceturate, or a pharmaceutically acceptable salt, solvate, ester, amide, clathrate, stereoisomer, enantiomer, or prodrug thereof.

Abstract: A number of improvements are provided relating to computer aided surgery utilizing an on tool tracking system. The various improvements relate generally to both the methods used during computer aided surgery and the devices used during such procedures. Other improvements relate to the structure of the tools used during a procedure and how the tools can be controlled using the OTT device. Still other improvements relate to methods of providing feedback during a procedure to improve either the efficiency or quality, or both, for a procedure including the rate of and type of data processed depending upon a CAS mode.

Abstract: The invention provides methods for using F16 isoindole small molecules for treatment of solid tumors, particularly brain cancers, such as glioblastoma multiforme (GBM). F16 isoindole is an inhibitor of angiogenesis and is capable of antagonizing tumor vasculature. The invention also provides pharmaceutical compositions including F16 isoindole small molecules.

Abstract: Systems and method for video communication using text-based compression in accordance with embodiments of the invention are illustrated. One embodiment includes a method for video communication using text-based compression, where the method includes receiving a file comprising captured audio-video content, encoding captured audio-video content to a text transcript using an encoder, transmitting initialization data, and the text transcript to a decoder, initializing a facial animation model and a text-to-speech (TTS) system using the initialization data, and reconstructing an animated version of the captured audio-video content using the text transcript, the facial animation model and the TTS system at the decoder.

Abstract: A method for assessing drug-resistant microorganism includes the following steps. A model establishing step is performed so as to obtain an antibiotic resistance assessing classifier. A test sample is provided. A sample pre-processing step is performed so as to obtain a processed sample. An analysis step is performed so as to obtain a target mass spectrum data. A spectrum pre-processing step is performed so as to obtain a normalized target mass spectrum data. A feature extraction step is performed so as to obtain a spectrum feature. An assessing step is performed, wherein the spectrum feature is analyzed by the antibiotic resistance assessing classifier so as to output an assessed result of drug-resistant microorganism, and the assessed result of drug-resistant microorganism is for assessing whether the test microorganism is a drug-resistant microorganism or not.

Abstract: Dry adhesives and methods for forming dry adhesives. A method of forming a dry adhesive structure on a backing material, comprises: forming a template backing layer of energy sensitive material on the backing material; forming a template layer of energy sensitive material on the template backing layer; exposing the template layer to a predetermined pattern of energy; removing a portion of the template layer related to the predetermined pattern of energy, and leaving a template structure formed from energy sensitive material and connected to the substrate via the template backing layer.

Abstract: In some implementations, the present solution can determine a first structural vector of a first chemical based on a chemical structure of the first chemical. The system can also determine first target vector of the first chemical based on at least one gene target for the first chemical. The system can use the structural vector and the target vector to generate a toxicity predictor score for the first chemical.

Abstract: A biometric information display apparatus (30) for displaying a measurement result obtained by measuring a biometric signal, includes a maximum value calculation unit (63) configured to calculate a maximum value of the measurement result in a certain period of time for at least one of blocks into which a measurement area, in which the biometric signal is measured, is divided, a determination unit (64) configured to determine whether a measurement value in the at least one of blocks is greater than or equal to a threshold value obtained by multiplying the maximum value by a fractional value, the fractional value being determined in advance, and a display control unit configured to display, in response to an occurrence of an event in which the measurement value is determined to be greater than or equal to the threshold value, the measurement result in such a manner as to indicate the occurrence of the event.

Abstract: An elastic wave cloaking lattice-based metamaterial for cloaking an object within a void includes a lattice of connected unit cells arranged to form a void, each unit cell comprising a mass and a plurality of connecting springs, the mass coupled by the plurality of connecting springs to masses in adjacent unit cells, the plurality of connecting springs comprising at least two large springs of a first length and at least two short springs of a second length, the first length greater than the second length, the springs and masses having relational and mechanical characteristics to facilitate elastic wave cloaking in the totality of the lattice. The lattice as a whole has metamaterial properties resulting from the positional relationship and mechanical properties of masses and connecting springs of the unit cells such that the lattice at least partially cloaks an object or material portioned within the void from elastic waves.

Abstract: The present invention provides a method for eddy current thermography defect reconstruction based on electrical impedance tomography, first, obtaining a thermal reference image of temperature change with time by acquiring a thermogram sequence S of the specimen in the process of heating and fitting a curve for pixels of each location of the thermogram sequence S, then, creating a current matrix and a magnetic potential matrix, and calculating the satisfied conductivity distribution through iterations, so as a reconstructed image is obtained, then taking the low conductivity area of the reconstructed image as the defect profile, thus the defect profile is identified and quantified.

Abstract: A power divider includes an input capacitor, and first and second transmission lines (TLs). The first TL includes an input portion (IP), a transmission portion (TP) and an output portion (OP). The second TL includes a TP and an OP. The IP is for receiving an input signal, and is connected to the TPs of the first and second TLs. For each of the first and second TLs, the TP has a length that is one-twelfth of a target wavelength, and is connected to the OP. The OPs of the first and second TLs are for cooperatively outputting a pair of output signals which are in-phase and each of which has a frequency equal to that of the input signal. The input capacitor is connected between ground and the IP.

Abstract: Provided is a memory management system based on a non-uniform memory access, which includes: a first persistent memory disposed in a first node; a second persistent memory disposed in a second node physically distinguished from the first node; a first journaling process disposed in the first persistent memory; and a second journaling process disposed in the second persistent memory.

Abstract: A two-stage medical image registration method based on progressive images (PIs) to solve the technical problem of low registration accuracy of traditional image registration methods includes: merging a reference image with a floating image to generate multiple intermediate PIs; registering, by a speeded-up robust features (SURF) algorithm and an affine transformation, the floating image with the intermediate PIs to acquire coarse registration results; registering, by the SURF algorithm and the affine transformation, the reference image with the coarse registration results to acquire fine registration results; and comparing the fine registration results of the intermediate PIs, which are acquired by iteration, and selecting an optimal registration result as a final registration image. The method can achieve multimodal registration for brain imaging with MI, NCC, MSD, and NMI superior to those of the existing registration algorithms.

Abstract: Systems and methods for automatic intravenous injection in accordance with embodiments of the invention are illustrated. One embodiment includes a method for automatically injecting a needle into a vein. The method includes steps for identifying an injection position using a first set of one or more sensors, positioning an injection mechanism at the identified injection position, and vertically inserting a needle until entry in a vein is detected using a second set of one or more sensors.