Abstract: The present invention relates to a technical idea of monitoring a heart condition by analyzing biosignals measured using a sensor device for detecting a heart condition. In a method of monitoring a heart condition according to one embodiment of the present invention, electrocardiogram signals are measured from a user, feature information is extracted by performing machine learning of the time domain of the measured electrocardiogram signals, a plurality of cardiac abnormality type models are determined by performing machine learning of the extracted feature information, classification accuracy for the determined cardiac abnormality type models is calculated, and a cardiovascular disease of the user is determined using the determined cardiac abnormality type models and public cardiovascular disease data based on the calculated accuracy. That is, the present invention relates to a technique for assisting medical diagnosis.

Abstract: A retrofitting method for a beam with an opening is disclosed. The retrofitting method provides a hoop cooperated with an inclined stirrup to form a reinforcement set. The hoop is used to enclose the opening; and the reinforcement set may be selectively adjusted according to the distance between the edge of opening and a column face. The retrofitting method and reinforcement set are not only suitable for openings located in the non-plastic hinge zone of the beam, but also suitable for the openings located in the plastic hinge zone.

Abstract: The present disclosure provides gene edited modified immune cells or precursors thereof (e.g., gene edited modified T cells) comprising an exogenous T cell receptor (TCR) and/or a chimeric antigen receptor (CAR) having specificity for a target antigen, and an insertion and/or deletion in one or more endogenous gene loci, wherein the endogenous gene loci encode regulators of T cell function, thereby resulting in immune cells having enhanced function. Compositions and methods of treatment are also provided. The present invention provides methods of screening for TCR- or CAR-T cells with enhanced immune function (e.g., T cell efficacy, T cell memory, and/or T cell persistence).

Abstract: A global navigation satellite system (GNSS) spoofing detection and classification technique is provided. An optimization problem is formulated at the baseband correlator domain by using an optimization algorithm such as the Least Absolute Shrinkage and Selection Operator (LASSO) algorithm, for example. A model of correlator tap outputs of the intended received signal is created to form a dictionary of pre-computed waveform functions (e.g., triangle-like-shaped functions). Sparse signal processing can be leveraged to choose a decomposition of pre-computed waveform functions from the dictionary. The optimal solution of this minimization problem can discriminate the presence of a potential spoofing attack peak by observing the decomposition of two different code-phase values (authentic and spoofed) in a sparse vector output. A threshold can be used to mitigate false alarms. Furthermore, a variation of the minimization problem can be provided that enhances the dictionary to a higher resolution.

Abstract: Responsive or degradable branched polymers may be prepared by the free radical polymerisation of a multivinyl monomer in the presence of a chain transfer agent, using a source of radicals, wherein the extent of propagation is controlled relative to the extent of chain transfer to prevent gelation of the polymer. The multivinyl monomer may comprise a cleavable group, for example an ester, or a multiplicity of such groups, between two vinyl groups. Said monomer may be a macromonomer containing multiple cleavage sites.

Abstract: The invention discloses a plant thermo-sensitive male sterile gene mutant tms15 and uses thereof. The nucleotide sequence of the plant thermo-sensitive male sterile gene mutant tms15 is SEQ ID No. 1. The inventor screened the thermo sensitive genic male sterile mutant tms15 by EMS mutagenesis of Zhonghua 11, which showed a male sterile phenotype under high temperature conditions (>28° C.) and restored fertility under low temperature conditions (22˜24° C.). The cytological results shows that the sporogenous cells in tms15 plants proliferated excessively and the tapetum cells are also vacuolized abnormally under high temperature. The normal proliferation of sporogenous cells and the normal development of tapetal cells are restored to some extent after low temperature treatment.

Abstract: Methods of cleanup for hydraulic fracturing operations using a polymeric thickening agent may include use of exothermically reactive salts. For example, a method of cleanup may include use of a first fluid including a first exothermically reactive salt and a second fluid including a second exothermically reactive salt. Upon introduction into a subterranean reservoir, exothermically reactive salts may undergo an exothermic reaction to generate heat, and such heat generated from the exothermic reaction may break a polymeric thickening agent and decrease viscosity thereof.

Abstract: A cell evaluation method includes acquiring a first evaluation index and a first index calculated using the first evaluation index with respect to comparative target cells in a culture process including a cell differentiation-inducing process in which cell differentiation is induced, calculating a second index on the basis of the first evaluation index with respect to evaluation target cells different from the comparative target cells, and evaluating differentiation of the evaluation target cells by comparing the first index with the second index.

Abstract: The present invention relates to the field of biomarkers. More specifically, the present invention relates to the use of biomarkers to predict post-traumatic stress disorder (PTSD). In one embodiment, a method for predicting PTSD in a subject comprises the steps of (a) measuring the DNA methylation level of a CpG dinucleotide in the 3? untranslated region of SKA2; (b) identifying the genotype at a SNP within the 3? UTR of SKA2, and (c) predicting PTSD in the subject using a prediction algorithm.

Abstract: An air handler unit for use with residential heating, ventilation, and air conditioning (HVAC) systems. The air handler unit has high resistance mediums (HRMs) coupled closely to a wide-angle vane-diffuser mixed-flow fan system. The HRMs are placed immediately upstream and downstream of the wide-angle vane-diffuser mixed-flow fan to form a closely coupled, compact air handler that provides significant efficiency and noise benefits.

Abstract: A form of a color-changeable plastic includes: a first conductive electrode layer; a color change layer disposed on the first conductive electrode layer, configured to cover a top surface of the first conductive electrode layer, and made of a substance that changes color depending on whether a voltage is applied; a second conductive electrode layer disposed on the color change laver, configured to cover a top surface and side surfaces of the color change layer, and configured to change the color of the color change layer with the first conductive electrode layer when the voltage is applied; and a conductive guide disposed at at least one of the first conductive electrode layer or the second conductive electrode layer, and configured to guide a movement of electrons and a color change direction of the color change layer when the voltage is applied.

Abstract: A plasma activated water production system includes a plasma reactor and a membrane concentrator. The plasma reactor includes an internal cavity, at least one electrically-conductive inlet capillary and outlet capillary. A mixing chamber has a feed gas inlet, a liquid inlet, and a mixed gas and liquid outlet. A power source is provided. The plasma reactor propagates a plasma discharge between the inlet capillary and the outlet capillary. A membrane concentrator includes a water flow channel with a water inlet and a water outlet, a dry gas inlet and a humidified gas outlet. An ion selective membrane is provided, and water will pass through the membrane into the dry gas, and the water leaving the membrane concentrator will have increased concentrations of nitrates, nitrites and hydrogen peroxide. An electrodialysis embodiment and a method of generating plasma activated with increased concentration of nitrates, nitrites and hydrogen peroxide are also disclosed.

Abstract: This disclosure pertains to a non-living biological product. Particularly, exosomes derived from stem cells can help restore heart function. According to certain embodiments, a fluid-induced shear stress mechanical stimulation process of stem cells is used to augmented quantity and quality of exosomes produced from stem cells. These exosomes serve as a therapeutic agent for the regenerative repair of diseases, such as diseased heart tissues. Therefore, compositions comprising the exosomes derived from stem cells and methods of treating a degenerative disease by administering the exosomes isolated from stem cells are also provided.

Abstract: A composite structural element includes a concrete member and a hollow member covering a part of a length of the concrete member. The concrete member has a first end, a second end, and a first elongated body extending between the first and second ends. The first elongated body has a first length between the first and second ends thereof. The hollow member has a first open end, a second open end, and a second elongated body extending between the first and second open ends. The second elongated body has a second length that is shorter than the first length. The hollow member may include a plurality of studs and a stiffener on its interior, in contact with the concrete member.

Abstract: The present invention relates to a biomarker composition for diagnosing and predicting prognosis of prostate cancer, and that the detection rate and expression level of gene combination composed with AR (Androgen receptor), AR-V7 (Androgen receptor variant 7), EpCAM (Epithelial cell adhesion molecule) in blood tumor cells (CTC) isolated from patients, Epithelial cell adhesion molecule), KRT-19 (Cytokeratin 19), PSA (Prostate specific antigen), and PSMA (Prostate specific membrane antigen) in circulating tumor cells (CTCs) isolated from patients is related to the level of malignancy in prostate cancer is confirmed and thus the gene combination provides as a biomarker for prostate cancer diagnosis and a biomarker for prognosis prediction of prostate cancer.

Abstract: Drying polar solvents which do not form hydrogen bonds with a wet gel or aerogel, or eutectics or solvent mixtures with the drying solvents, are utilized in a solvent exchange with wet gels used in the formation of aerogels. Preferably the drying solvents are non-polar solvents. The drying solvent or solvent mixtures results in profoundly less shrinkage, thereby allowing for the production of aerogels of preferred materials properties.

Abstract: Disclosed is a rare earth complex having a rare earth ion and a phosphine oxide ligand that is coordinated with the rare earth ion and is represented by the following formula (I): wherein R1, R2, R3, R4, R5, and R6 each independently represent an alkyl group which may have a substituent.

Abstract: Disclosed is a biped robot and multi-configuration robot capable of being spliced autonomously, and a control method of the multi-configuration robot. The biped robot comprises a torso, arms, legs, a tolerance docking sleeve, and a torso docking device. The arms are correspondingly arranged at the left and right sides of the torso, and two legs are arranged at the lower side of the torso. The tolerance docking sleeve is movably arranged at the rear side of the torso through a base, and the torso docking device is fixed to the front side of the torso. Single biped robots in the present disclosure can form a multi-configuration legged combined body in a self-organization and reconstruction mode so as to achieve bipedal, quadrupedal, hexapodal and other multi-legged configurations. The motion stability and the load capacity of the legged robot are improved through the splicing combination of the modular legged robots.

Abstract: The present invention provides a flocculant for catalytic decomposition of flue gas desulfurization wastewater treatment. The flocculant includes polyacrylamide, inorganic polymer, and an inorganic compound with low molecular weight. In the condition of using proper components, the flocculant has significant wastewater treatment performance.

Abstract: Provided is a method for producing a stem cell-derived lacrimal gland tissue, the method comprising isolating SSEA4 and CD104 double positive cells from a self-formed ectodermal autonomous multi-zone (SEAM) cell population derived from pluripotent stem cells and three-dimensionally culturing the isolated cells in a medium with epidermal growth factor (EGF) and a ROCK inhibitor to produce a cell population expressing a lacrimal gland-related protein. The present invention provides a lacrimal gland organoid produced from pluripotent stem cells including iPS cells and thus is very useful for cell-based regenerative therapy for lacrimal gland-related diseases and cell-based research on the diseases.