Patents Assigned to University
  • Patent number: 11141491
    Abstract: Currently, the present invention provides a pH-sensitive lipid nanoparticle, comprising: a nanoparticle core composed of a mixture of lipid and/or surfactant, and the surface of the nanoparticle core comprising: a imine-omPEG, the imine is a pH-sensitive linker; and a PEG-peptide, wherein the peptide is selected from the group consisting of a RF peptide, a K peptide, and a H peptide; wherein the RF peptide is a potent CPP, the K peptide is a mitochondria-targeting peptide and the H peptide is a cancer specific binding peptide; a lipid, inside the nanoparticle core; wherein the lipid nanoparticle encapsulating a targeting agent.
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: October 12, 2021
    Assignee: National Yang Ming Chiao Tung University
    Inventor: Yu-Li Lo
  • Patent number: 11142909
    Abstract: Disclosed are methods for incorporating core materials such as phase change materials or admixtures into building materials like concrete. The methods use cenospheres, which are then etched and loaded with the core material. The composition can also be coated with a thin film. Compositions containing cenospheres loaded with the various core materials are disclosed, as are building materials containing such compositions.
    Type: Grant
    Filed: September 17, 2019
    Date of Patent: October 12, 2021
    Assignee: The Board of Trustees of the University of Alabama
    Inventor: Jialai Wang
  • Patent number: 11143169
    Abstract: Actuators (artificial muscles) comprising twist-spun nanofiber yarn or twist-inserted polymer fibers generate torsional actuation when powered electrically, photonically, chemically, thermally, by absorption, or by other means. These artificial muscles utilize coiled yarns/polymer fibers and can be either neat or comprising a guest. In some embodiments, the actuator system includes a twisted and coiled polymer fiber actuator, and at least one of (i) wire connections that enable electrical heating of the twisted and coiled polymer fiber actuator, (ii) a radiation source and radiation pathway that enables photothermal heating of the twisted and coiled polymer fiber actuator, and (iii) a delivery system for delivering chemicals whose reaction produces heating of the twisted and coiled polymer fiber actuator.
    Type: Grant
    Filed: October 9, 2019
    Date of Patent: October 12, 2021
    Assignee: Board of Regents, The University of Texas System
    Inventors: Na Li, Carter S. Haines, Marcio D. Lima, Monica Jung DeAndrade, Shaoli Fang, Jiyoung Oh, Mikhail E. Kozlov, Dongseok Suh, Ray H. Baughman
  • Patent number: 11145636
    Abstract: A method for making inkjet-printed encapsulated quantum dots and a light conversion unit using the inkjet-printed encapsulated quantum dots are disclosed. The light conversion unit comprises: a substrate, a light convertor carrying layer having several accommodating grooves, several first micro encapsulated QD structures, and several second micro encapsulated QD structures. In case of letting the substrate has a hydrophobic surface, at least one inkjet-printing nozzle is utilized for injecting a first QDs solution and a second QDs solution into the accommodating grooves by a form of droplet, such that one third of the accommodating grooves are formed with the first micro encapsulated QD structure, and another one third of the accommodating grooves formed with the second micro encapsulated QD structure. Moreover, a micro LED display panel having the light conversion unit exhibits a color gamut that is approximately 110% NTSC.
    Type: Grant
    Filed: July 2, 2020
    Date of Patent: October 12, 2021
    Assignee: National Tsing Hua University
    Inventors: Hsueh-Shih Chen, Shih-Jung Ho
  • Publication number: 20210309681
    Abstract: A preparation method and use of a graphite felt (GF)-supported metal-organic framework (MOF) cathode material is disclosed. The preparation method includes the following steps: preparing an iron salt, Pluronic F127, a weak acid, 2-aminoterephthalic acid, and a carbon felt; adding the iron salt and Pluronic F127 to deionized water and stirring a resulting mixture; adding the weak acid and 2-aminoterephthalic acid to the mixture, and stirring a resulting mixture to obtain an MOF precursor solution; adding the MOF precursor solution together with a pretreated carbon felt to a reactor, and sealing the reactor for hydrothermal reaction; and washing and vacuum drying a reaction product to obtain the cathode material. With a porous structure and a large specific surface area (SSA), the cathode material significantly increases the output of H2O2 when used in an electric Fenton system.
    Type: Application
    Filed: March 18, 2021
    Publication date: October 7, 2021
    Applicant: Tongji University
    Inventors: Ying WANG, Fengting LI, Bincheng XU
  • Publication number: 20210313016
    Abstract: A processing workflow centered on machine-learning algorithms that identifies a number of chemical features that can best distinguish the presence or absence of a chemical source. These chemical features are a chemical fingerprint that is unique to each source. The analysis workflow is rapid (e.g., fingerprints can be generated in minutes). The analysis workflow has wide-ranging applications such as detecting markers of pollution sources in rivers and fish tissues, forest pathogen outbreaks, and hard-to-diagnose diseases.
    Type: Application
    Filed: March 29, 2021
    Publication date: October 7, 2021
    Applicant: Oregon State University
    Inventor: Gerrad Jones
  • Publication number: 20210310895
    Abstract: Robotic devices that can be utilized on pipes of any material and of a variety of pipe diameters are provided. The robotic device utilizes a ducted fan to create the normal forces needed to adhere to any part of a pipe. The chassis of the device can be segmented to allow for application on various diameter pipes.
    Type: Application
    Filed: April 2, 2021
    Publication date: October 7, 2021
    Applicant: The Florida International University Board of Trustees
    Inventors: Dwayne E. McDaniel, Mackenson Telusma, Leonel E. Lagos
  • Publication number: 20210309544
    Abstract: A denitrification system for removing nitrates in a water body by electrocatalytic hydrogen evolution and catalytic hydrogenation is disclosed. The denitrification system includes an electrolytic cell and a three-electrode system inserted into the electrolytic cell. The electrolytic cell contains electrolyte solution, and the denitrification catalyst is dispersed and suspended in the electrolyte solution. The three-electrode system includes a working electrode, a counter electrode and a reference electrode. The counter electrode adopts Pt sheet, the working electrode adopts the catalyst Ni3S2—NF, and the preparation steps of the catalyst Ni3S2—NF are as follows: (i) cutting a certain size nickel mesh and cleaning it; (ii) adding the cleaned nickel mesh into thiourea solution; (iii) reacting under hydrothermal conditions, and washing and drying to obtain the catalyst Ni3S2—NF.
    Type: Application
    Filed: August 27, 2020
    Publication date: October 7, 2021
    Applicant: Tongji University
    Inventors: Jianwei FAN, Zhangqiang HU, Weixian ZHANG, Xianqiang RAN, Wei TENG
  • Publication number: 20210311046
    Abstract: Among the various aspects of the present disclosure is the provision of a method of reducing interference (e.g., the Hook effect) in an immunoassay (e.g., a single-step homogeneous turbidometric or nephelometric immune assay).
    Type: Application
    Filed: April 7, 2021
    Publication date: October 7, 2021
    Applicant: Washington University
    Inventors: Mark A. Zaydman, Jonathan R. Brestoff Parker, Ann Marie Gronowski
  • Publication number: 20210311063
    Abstract: A reliable assay to specifically detect CD155 in tissue sections has widespread use because CD155 is expressed widely among tumor types. Additionally, detected expression of CD 155 in glioblastoma cells is at levels commensurate with susceptibility to PVSRIPO (a poliovirus construct) infection and killing. An anti-CD155 antibody can achieve mono-specific detection of CD155 in immunoblots of tumor homogenates and immunohistochemistry of tumor formalin fixed, paraffin embedded sections. The assay can be used to determine appropriate use of PVSRIPO in oncolytic immunotherapy against cancers.
    Type: Application
    Filed: October 2, 2017
    Publication date: October 7, 2021
    Applicant: Duke University
    Inventors: Darell D. Bigner, Vidyalakshmi Chandramohan, Matthias Gromeier
  • Publication number: 20210311075
    Abstract: Provided herein are methods for determining whether a subject has an increased likelihood of having a disorder related to abnormal intracellular calcium store discharge. In some embodiments, the method is useful for determining whether the subject has an increased likelihood of having a neurodegenerative disease, skeletal muscle disease, cardiac muscle disease, autoimmune disease, cancer, diabetes, or has been exposed to an environmental pollutant. Kits are also provided herein.
    Type: Application
    Filed: January 29, 2020
    Publication date: October 7, 2021
    Applicant: The Regents of the University of California
    Inventor: Alla F. FOMINA
  • Publication number: 20210310918
    Abstract: A specimen heating apparatus includes a heater unit configured to heat a test specimen held in a material testing machine, a heater holding unit configured to hold the heater unit in a set position relative to the test specimen for heating, a specimen temperature measurement unit attached to the heater unit and configured to measure temperature of the test specimen when the heater unit is in the set position, a temperature controller configured to control heating of the heater unit in response to a temperature measured by the specimen temperature measurement unit, and a thermal insulation unit configured to cover the heater unit, wherein the heater holding unit holds the heater unit in such a way that the heater unit is allowed to be brought to and removed from the set position while the test specimen is being held in the material testing machine.
    Type: Application
    Filed: June 21, 2021
    Publication date: October 7, 2021
    Applicant: King Abdulaziz University
    Inventor: Mohammed ALGARNI
  • Publication number: 20210307589
    Abstract: A medical device includes an elongate body and an inflatable balloon attached to and partially surrounding at least a section of the elongate body. The inflatable balloon is selectively inflatable between a deflated state and an inflated state. Engagement between the balloon and a physiological lumen is provided, in part, by multiple protrusions extending from the inflatable balloon and having various physical and functional characteristics. In certain implementations, the balloon may be configured to exhibit various separation forces by applying different strains to the balloon, such as by varying the degree to which the balloon is inflated or deflated.
    Type: Application
    Filed: June 22, 2021
    Publication date: October 7, 2021
    Applicant: The Regents of the University of Colorado, a Body Corporate
    Inventors: Mark E. Rentschler, Steven A. Edmundowicz, Karl Johannes
  • Publication number: 20210310928
    Abstract: An open-ended hollow coaxial cable resonator probe configured to receive an aerosol sample for analysis. A metal post shorts the resonator's inner and outer conductors. A metal plate is spaced apart from an open end of the resonator by a dielectric layer that contains the received aerosol sample. Interrogator circuitry coupled to the resonator transmits an electromagnetic wave within the resonator and generates an electric field at the open end of the resonator. The interrogator circuitry is responsive to the generated electric field for determining a resonance frequency and an impedance of the resonator when the aerosol sample is present in the dielectric layer and is configured to identify virus particles in the aerosol sample as a function of the determined resonance frequency and impedance. A portable aerosol analyzer comprises the open-ended hollow coaxial cable resonator and a mouthpiece through which a subject expels a breath sample into the open end of the resonator.
    Type: Application
    Filed: March 23, 2021
    Publication date: October 7, 2021
    Applicant: The Curators of the University of Missouri
    Inventors: Jie Huang, Chen Zhu, Rex E. Gerald, II
  • Publication number: 20210307597
    Abstract: An oral and oropharyngeal cancer screening system and associated methods are disclosed. In at least one embodiment, the screening system provides an at least one oral and oropharyngeal cancer screening device configured for selectively capturing images of an oropharyngeal area of an at least one patient. The screening device provides an elongate, relatively compact housing, a distal end of the housing being selectively bendable. An imaging module is positioned within the housing, the imaging module providing a lens, an at least one light source, and an imaging sensor positioned in the distal end of the housing. A user application resides in memory on an at least one user device in selective communication with the at least one screening device. The user application is configured for receiving images captured by the at least one screening device and recording risk factors, automatically analyzing the captured images and potential health-risk factors to screen for OPML and oral and oropharyngeal risk.
    Type: Application
    Filed: July 22, 2019
    Publication date: October 7, 2021
    Applicants: The Regents of the University of California, Arizona Board of Regents on Behalf of the University of Arizona
    Inventors: Petra Beate Wilder Smith, Rongguang Liang
  • Publication number: 20210313120
    Abstract: The disclosed photoconverter is related to the technology of thin-film hybrid semiconductor photoconverters. Thin-film hybrid photoconverters with heterojunctions and layers is modified with Ti3C2Tx MXenes for use in visible sunlight spectrum and UV-IR regions (380 to 780 nm). The device with absorber layer of metal-organic APbX3 perovskites was fabricated in n-i-p and p-i-n configurations, including structures with carbon electrodes, and stabilized characteristics were stabilized by introduction of thin Ti3C2Tx MXene layers (5-50 nm) at the junction and contact interfaces, i.e., APbX3 perovskite absorber layer/MXene, electron transport layer/MXene, cathode electrode/MXene, as well as by doping of carbon electrode for reduction of the work function by incorporating of MXenes into the bulk of material with appropriate weight percentage for providing ohmic contact with higher efficiency of charge collection.
    Type: Application
    Filed: September 20, 2019
    Publication date: October 7, 2021
    Applicant: Natonal University of Science and Technology MISIS
    Inventors: Anna Ivanovna PAZNIAK, Danila Sergeevich SARANIN, Dmitry Sergeevich MURATOV, Pavel Andreevich GOSTISHCHEV, Sergei Ivanovich DEDENKO, Denis Valerievich KUZNETSOV, Al'do Dl CARLO
  • Publication number: 20210307779
    Abstract: A thrombectomy device includes a handle at a proximal end portion of the device, a cage at a distal end portion of the device, the cage being moveable between an expanded orientation and a contracted orientation, and a first tube extending from the proximal end portion of the device to at least a proximal end portion of the cage. The device also includes a second tube extending from the proximal end portion of the device to at least a distal end portion of the cage, and a self-adjusting control assembly including a biasing element coupled to one of the first tube or the second tube. The biasing element exerts an axial force to urge the cage toward the expanded orientation.
    Type: Application
    Filed: April 30, 2021
    Publication date: October 7, 2021
    Applicant: National University of Irland, Galway
    Inventors: Mark BRUZZI, Saeid Kasiri Ghahi, Paul Heneghan
  • Publication number: 20210312183
    Abstract: A system and method are provided for accurately recognizing actions and estimating action intensity. To enable the system to deal with the uncertainty and varied nature inherent in action recognition and intensity indexing, the system is a hybrid system that combines the concept of fuzzy logic and deep recurrent neural networks. The methodology is an attentive neuro-fuzzy system designed to recognize qualitative differences in human actions and to self-adapt to different intensities. The model of the system and method utilizes recurrent neural networks to detect actions from spatio-temporal patterns of human poses, in tandem with an adaptive fuzzy inference system to learn the various human motions used to perform actions with different intensities and then estimate the action's intensity. The integrated model can successfully learn the unique way a specific action with a certain intensity is performed and can estimate the intensity of the respective action.
    Type: Application
    Filed: April 5, 2021
    Publication date: October 7, 2021
    Applicant: Board of Regents, The University of Texas System
    Inventors: Nihar Shrikant Bendre, Nima Ebadi, Peyman Najafirad
  • Publication number: 20210313015
    Abstract: The present invention provides a method for obtaining a specifically-shaped crystal (specifically, spherocrystal) of a compound with good reproducibility. This method for producing a specifically-shaped crystal (specifically spherocrystal) of a compound comprises: (1) a step for preparing a supersaturated solution of a compound having a degree of supersaturation equal to or higher than a critical degree of supersaturation; and (2) a step for precipitating a specifically-shaped crystal (specifically spherocrystal) of a compound from the supersaturated solution.
    Type: Application
    Filed: August 21, 2019
    Publication date: October 7, 2021
    Applicants: TOWA PHARMACEUTICAL CO., LTD., The University of Tokyo
    Inventors: Junpei Sukegawa, Daigo Araki, Shunpei Suzuki, Masaki Minami, Takuma Onai, Fumihiro Wakita, Chao Liu, Eiichi Nakamura, Koji Harano
  • Publication number: 20210308278
    Abstract: The present invention provides a nanogel nasal vaccine that induces cell-mediated immunity. Specifically, the present invention relates to a vaccine preparation comprising a complex of a nanogel, a vaccine antigen, and an adjuvant, wherein the vaccine preparation can efficiently induce the cell-mediated immunity, and can also induce a systemic and mucosal immune response.
    Type: Application
    Filed: August 2, 2019
    Publication date: October 7, 2021
    Applicants: The University of Tokyo, HANAVAX INC.
    Inventors: Yoshikazu YUKI, Rika NAKAHASHI, Hiroshi KIYONO