Patents Assigned to University
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Publication number: 20210308287Abstract: Disclosed herein are methods preparing a purified, carrier-free 68Ga solution. Tire present disclosure also provides systems for preparing a purified, carrier-free 68Ga solution. The present disclosure also provides compositions comprising the purified, carrier-free 68Ga solutions disclosed herein. Also provided are methods of administering compositions of the present disclosure to a patient in need thereof, for example, for imaging a disease or disorder, such as cancer.Type: ApplicationFiled: August 2, 2019Publication date: October 7, 2021Applicant: Board of Regents, The University of Texas SystemInventors: Mai LIN, Carlos E. GONZALEZ-LEPERA
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Publication number: 20210310046Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.Type: ApplicationFiled: December 15, 2020Publication date: October 7, 2021Applicant: University of WashingtonInventors: Georg Seelig, Richard Muscat, Alexander B. Rosenberg
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Publication number: 20210310074Abstract: The application provides methods of prognosing and classifying uterine serous carcinoma (USC) patients into poor survival groups or good survival groups and for predicting response to therapy by way of a multigene signature. The application also includes kits and computer products for use in the methods of the application.Type: ApplicationFiled: February 11, 2021Publication date: October 7, 2021Applicant: Augusta University Research Institute, Inc.Inventors: Jin-Xiong She, Lynn Tran
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Publication number: 20210307611Abstract: a) A Gabor domain optical coherence microscopy (GD-OCM) system providing high resolution of structural and motion imaging of objects such as tissues is combined with the use of reverberant shear wave fields (RevSW) or longitudinal shear waves (LSW) and two novel mechanical excitation sources: a coaxial coverslip excitation (CCE) and a multiple pronged excitation (MPE) sources providing structured and controlled mechanical excitation in tissues and leading to accurate derivation of elastographic properties. Alternatively, general optical computed tomography (OCT) is combined with RevSW or LWC in the object to derive elastographic properties. The embodiments include (a) GD-OCM with RevSW; (b) GD-OCM with LSW; (c) General OCT with RevSW; and General OCT with LSW.Type: ApplicationFiled: April 2, 2020Publication date: October 7, 2021Applicant: University of RochesterInventors: Jose Fernando ZVIETCOVICH ZEGARRA, Jannick P. Rolland, Cristina Canavesi, Kevin J. Parker
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Publication number: 20210308319Abstract: An absorbable medical article comprising: an absorbable polymeric substrate; and an absorbable composition disposed on at least a portion of a surface of the substrate, wherein the absorbable composition comprises: (i) at least one absorbable coating polymer distinct from the substrate and (ii) a colorant that is miscible with the absorbable coating polymer.Type: ApplicationFiled: August 1, 2019Publication date: October 7, 2021Applicant: University of Pittsburgh - Of the Commonwealth System of Higher EducationInventors: Eric J. Beckman, Joseph P. Rubin, Stephen D. Cummings
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Publication number: 20210310174Abstract: Disclosed is an integrated washing and spinning tub and an energy-saving and healthy household washing machine with a tub replacing function. The integrated washing and spinning tub comprises a water holding tub, a spinning tub is arranged in the water holding tub, and the water holding tub and the spinning tub are connected in a sliding groove mode. The energy-saving and healthy household washing machine with a tub replacing function comprises a washing machine shell, the integrated washing and spinning tub is arranged in the washing machine shell, a spring telescopic support corresponding to the integrated washing and spinning tub is arranged on the inner wall of the upper portion of the washing machine shell, a support frame is arranged at the bottom of the integrated washing and spinning tub, and a reduction gear and a motor which are connected are arranged on the support frame.Type: ApplicationFiled: March 31, 2021Publication date: October 7, 2021Applicant: Zhejiang UniversityInventors: De DING, Junxiang YU, Yiqun JIN
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Publication number: 20210310266Abstract: A double variable sliding isolator including a bottom sliding plate, a top sliding plate, and a friction piece is provided. The bottom sliding plate has a bottom sliding surface that has at least two curvatures. The top sliding plate is disposed over the bottom sliding plate and has a top sliding surface that has at least two curvatures. The friction piece is disposed between the top sliding plate and the bottom sliding plate and the friction piece is in contact with the bottom sliding surface and the top sliding surface. When an external force is applied to the bottom sliding plate and the top sliding plate, the bottom sliding plate and the top sliding plate will generate a relative displacement, so that the friction piece slides along the bottom sliding plate and the top sliding plate.Type: ApplicationFiled: April 6, 2020Publication date: October 7, 2021Applicants: National Cheng-Kung University, WELL-LINK INDUSTRY Co.,LTDInventors: Lyan-Ywan Lu, Han-Wei Huang, Chun-Lung Lee
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Publication number: 20210309683Abstract: Disclosed is a method for synthesizing an 0-antigen saccharide chain of Helicobacter pylori serotype O:6 using seven glycosylation building blocks. Inexpensive and easily available D-glucosamine, D-galactose, D-mannose and L-fucose are used as starting materials, and seven glycosylation building blocks are obtained through a series of chemical reactions. The saccharide building blocks are then selectively linked together to produce O-antigen oligosaccharide chains of Helicobacter pylori serotype O:6 with different saccharide configuration through a series of glycosylation reactions. Also disclosed is a method to assemble an amino linker at the reducing end of the O-antigen saccharide chain of Helicobacter pylori serotype O:6, and the synthesized oligosaccharide chain with an amino linker can be coupled to a carrier molecule or immobilized on a matrix.Type: ApplicationFiled: April 2, 2021Publication date: October 7, 2021Applicant: JIangnan UniversityInventors: Jian Yin, Jing Hu, Guangzong Tian
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Publication number: 20210308520Abstract: A treadmill may be configured for gait training and/or therapy with attachable/detachable barriers affixable to a belt and/or with a vertical obstacle module and/or with sensor systems, but without requiring hoists, harnesses, attachments to the treadmill or base, or frame, and/or excessively high treadmill frames, such as those that exceed the height of the person on the treadmill. The barriers on the belt are configured to modify movement of only one foot of a person on the treadmill. The treadmill may use a single, integral belt. Methods of gait training and/or therapy may involve such treadmills without excessive expense and without excessive modification of standard treadmill equipment.Type: ApplicationFiled: June 22, 2021Publication date: October 7, 2021Applicant: King Abdulaziz UniversityInventors: Nazeeh ALOTHMANY, Ehab Hafiz WALI, Abdulhameed ALKHATEEB, Umar ALABASI, Mirza PASOVIC
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Publication number: 20210313561Abstract: A positive electrode for a solid-state lithium battery, the positive electrode including: a positive active material; and a first solid electrolyte, wherein a ratio ? of an average particle diameter of the positive active material to an average particle diameter of the first solid electrolyte is 3???40, wherein the positive active material has an average particle diameter of 1 ?m to 30 ?m, and wherein the first solid electrolyte has an average particle diameter of 0.1 ?m to 4 ?m.Type: ApplicationFiled: June 15, 2021Publication date: October 7, 2021Applicants: Samsung Electronics Co., Ltd., The Regents of the University of CaliforniaInventors: Qingsong Tu, Tan Shi, Gerbrand Ceder, Lincoln Miara
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Publication number: 20210309577Abstract: A method of producing polycrystalline Y3Ba5Cu8Oy (Y-358) whereby powders of yttrium (III) oxide, a barium (II) salt, and copper (II) oxide are pelletized, calcined at 850 to 950° C. for 8 to 16 hours, ball milled under controlled conditions, pelletized again and sintered in an oxygen atmosphere at 900 to 1000° C. for up to 72 hours. The polycrystalline Y3Ba5Cu8Oy thus produced is in the form of elongated crystals having an average length of 2 to 10 ?m and an average width of 1 to 2 ?m, and embedded with spherical nanoparticles of yttrium deficient Y3Ba5Cu8Oy having an average diameter of 5 to 20 nm. The spherical nanoparticles are present as agglomerates having flower-like morphology with an average particles size of 30 to 60 nm. The ball milled polycrystalline Y3Ba5Cu8Oy prepared under controlled conditions shows significant enhancement of superconducting and flux pinning properties.Type: ApplicationFiled: June 21, 2021Publication date: October 7, 2021Applicant: Imam Abdulrahman Bin Faisal UniversityInventor: Yassine SLIMANI
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Publication number: 20210310924Abstract: Time multiplexing an electromagnetic trap beam may be used to generate trap shapes/geometries to trap one or more particles with one electromagnetic beam by directing the electromagnetic beam at a pattern of different locations with sufficient rapidity to form an effective shape/geometry. Additionally, multiplexing an electromagnetic trap beam may be used to shutter trapping electromagnetic radiation to protect a viewer, use the same beam for multiple functions, move and organize particles, and generate illumination effects.Type: ApplicationFiled: March 15, 2021Publication date: October 7, 2021Applicant: Brigham Young UniversityInventors: Daniel Smalley, Braden Huffman, Stephen Griffith
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Publication number: 20210312612Abstract: A method and apparatus uses multi-material decomposition of three or more material components to generate material-component images from spectral images reconstructed from spectral computed tomography data. In three-component material decomposition e.g., the Mendonça method is used for multi-material decomposition when the attenuation values satisfy an assumed volume fraction condition (i.e., for a given voxel, the attenuation values are within a triangle having vertices given by unit volume fractions of three respective material components). However, when the volume fraction condition fails (e.g., the attenuation values are outside the triangle), either a shortest-Hausdorff-distance method or a closest-edge method is used for multi-material decomposition. For example, the attenuation values of the voxel are projected onto a lower-dimensional space (e.g., the space of a closest edge) and decomposed into a pair/single material component(s) of the lower-dimensional space.Type: ApplicationFiled: April 3, 2020Publication date: October 7, 2021Applicants: The University of Chicago, CANON MEDICAL SYSTEMS CORPORATIONInventors: Dimple MODGIL, Patrick La Riviere, Yan Liu, Zhou Yu
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Publication number: 20210311213Abstract: A method and system for generating a hybrid positron emission tomography (PET) scanner are disclosed herein. An imaging system receives, from the hybrid PET scanner, a first set of image data of an object corresponding to high-resolution, low-sensitivity image data. The imaging system receives, from the hybrid PET scanner, a second set of image data of the object corresponding to low-resolution, high-sensitivity image data. The imaging system converts the second set of image data from low-resolution, high-sensitivity image data to high-resolution, high-sensitivity image data. The imaging system combines the high-resolution, high-sensitivity image data with the high-resolution, low-sensitivity image data. The imaging system generates an image of an object based on the combined high-resolution, high-sensitivity image data and the high-resolution, low-sensitivity image data, or high-resolution, high-sensitivity image data only.Type: ApplicationFiled: April 6, 2021Publication date: October 7, 2021Applicant: The Board of Regents of the University of Texas SystemInventor: Yiping Shao
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Publication number: 20210311218Abstract: The present method predicts and separates dispersive surface waves from seismic data using dispersion estimation and is completely data-driven and computer automated and no human intervention is needed. The method is capable of predicting and suppressing surface waves from recorded seismic data without damaging the reflections. Nonlinear signal comparison (NLSC) is used to obtain a high resolution and accurate dispersion. Based on the dispersion, surface waves are predicted from the field recorded seismic data. The predicted surface waves are then subtracted from the original data.Type: ApplicationFiled: August 7, 2019Publication date: October 7, 2021Applicant: University of Houston SystemInventors: Yingcai Zheng, Hao Hu
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Publication number: 20210310910Abstract: Herein are innovations that enable facile cryo-EM analysis of diverse samples. Methods of functionalizing sample grids for cryo-EM are described, including methods of creating high quality graphene oxide films on cryo-EM substrates. The cryo-EM sample substrates are functionalized with affinity molecules that efficiently concentrate sample molecules and other specimen types on the grid, away from the air-water interface. Affinity groups include amines and proteins such as tagging system proteins and peptides that can be used to capture diverse sample types with high affinity. Optionally, spacers such as PEG chains are used to place sample particles away from the substrate surface, reducing substrate-induced artifacts.Type: ApplicationFiled: August 19, 2019Publication date: October 7, 2021Applicant: The Regents of the University of CaliforniaInventors: Feng Wang, David Agard, Yifan Cheng, Eugene Palovcak
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Publication number: 20210311248Abstract: An interferometric optical fibre sensor comprises optical fibre defining an optical circuit configured to propagate a first optical wave via an environment in which the optical fibre can be exposed to a stimulus that modifies the first optical wave, and a second optical wave, and to combine the first optical wave and the second optical wave to create an interference signal containing information about the stimulus, wherein optical fibre propagating either or both of the first optical wave and the second optical wave comprises hollow core optical fibre configured to propagate the optical wave or waves by an antiresonant optical guidance effect.Type: ApplicationFiled: August 5, 2019Publication date: October 7, 2021Applicant: University of SouthamptonInventors: Austin Taranta, Eric Numkam-Fokoua, Francesco Poletti, David Neil Payne
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Publication number: 20210311066Abstract: Enzymes that reduce specific metal or metalloid ions to insoluble form are important to science. Peptides isolated from yeast- and phage-display libraries can affect the size and morphology of inorganic materials during their synthesis. Herein, an Se binding peptide was fused to an enzyme capable of reducing selenite (SeO32?) to a Se0 nanoparticle (SeNP). The fusion of the Se binding peptide to the metalloid reductase provided size control of the resulting SeNP. The SeNP product also remains associated to the enzyme fusion. The Se binding peptide fusion to the enzyme increases the enzyme's SeO32? reductase activity. Modification of enzyme activity was absent, and the size control of particles was diminished when the Se binding peptide was added exogenously to the reaction mixture. Binding of the peptide is attributed to His based ligation that results in a conformational change to the peptide.Type: ApplicationFiled: August 9, 2019Publication date: October 7, 2021Applicant: Colorado State University Research FoundationInventors: Christopher J. ACKERSON, Zachary BUTZ, Richard NEMETH, Ryan RISKOWSKI, Kanda BORGOGNONI
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Publication number: 20210310700Abstract: The present invention discloses a radiative cooling device and a method of manufacturing the same. Specifically, the radiative cooling device according to an embodiment of the present invention includes a reflective layer formed on a substrate and responsible for reflecting sunlight having wavelengths corresponding to ultraviolet, visible, and near-infrared regions; and a radiative cooling layer formed on the reflective layer and responsible for absorbing sunlight having a wavelength corresponding to a mid-infrared region and emitting the sunlight as heat, wherein the radiative cooling layer includes a first radiation layer including an uneven pattern; and a second radiation layer formed on the first radiation layer and having a refractive index different from that of the first radiation layer.Type: ApplicationFiled: October 14, 2020Publication date: October 7, 2021Applicant: Korea University Research and Business FoundationInventors: Heon LEE, Pil-Hoon JUNG, Soomin SON, Dongwoo CHAE, Yuting LIU
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Publication number: 20210311021Abstract: Systems and methods are provided for simultaneously assaying cell adhesion or cell rolling for multiple cell specimens. One embodiment provides a system for assaying adhesion or cell rolling of multiple cell specimens that includes a confocal imaging system containing a parallel plate flow chamber, a pump in fluid communication with the parallel plate flow chamber via a flow chamber inlet line and a cell suspension in fluid communication with the parallel plate flow chamber via a flow chamber outlet line. The system also includes a laser scanning system in electronic communication with the confocal imaging system, and a computer in communication with the confocal imaging system and laser scanning system. In certain embodiments, the laser scanning system emits multiple electromagnetic wavelengths simultaneously it cause multiple fluorescent labels having different excitation wavelength maximums to fluoresce.Type: ApplicationFiled: November 28, 2016Publication date: October 7, 2021Applicant: King Abdullah University of Science and TechnologyInventors: Jasmeen Merzaban, Ayman F. Abuelela, Amal J. Ali