Abstract: This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as neoplasia of the upper or lower gastrointestinal tract, pancreas, and/or bladder.

Abstract: An augmented reality system includes a first scene and a second scene. Further, the augmented reality system includes a partially reflective surface positioned relative to the first scene, the second scene, and an audience to facilitate viewing of one of the first scene or the second scene through the partially reflective surface and to facilitate reflection of the other of the first scene or the second scene toward the audience as augmented reality imagery. A sensor of the augmented reality system is designed to detect and generate data indicative of a characteristic of the first scene, and a correlative effect system is operable to receive the data and adjust the second scene based thereon.

Abstract: The present invention is provided with an imaging unit (10) that has an imaging head (11) to be inserted into the digestive tract (112) and images a living body by applying a laser to the digestive tract (112) via the imaging head (11); a control unit (50) for controlling the imaging head (11) to move inside the digestive tract (112); and an image processing unit (70) for processing an image captured by the imaging unit (10). The imaging unit (10) captures a plurality of imaging regions (P) to be imaged along with the movement of the imaging head (11) such that a portion of adjacent imaging regions (P1, P2) overlap, and the image processing unit (70) overlaps regions (Pa) in which the plurality of imaging regions (P1, P2) are overlapped to generate a composite image.

Abstract: Provided are methods for producing mesoporous nanoparticles that can, once loaded, retain small or large molecules (e.g., molecules having a molecular weight that is less or greater than about 900 Da) until release is desired, upon which time the mesoporous nanoparticles can release the loaded molecule in a controlled manner for a desired period of time, including an extended period of time. Also disclosed are methods for treating a subject comprising administering to the subject a mesoporous nanoparticle according to the present disclosure.

Abstract: A universal color coding system, and a system and a method of manipulating colors using such color coding system. The color coding system includes a color mapper arranged to map a plurality of colors with a plurality of numerical codes, wherein the each of the plurality of numerical codes is a unique integer determined based on a combination of prime numbers.

Abstract: Various liquid and semisolid lubricant compositions are provided, in particular lubricant compositions containing oil from the seeds of the Brassicaceae Orychophragmus violaceus, preferably those that have been esterified with one or more fatty acids such as palmitoleic acid, oleic acid, linoleic acid, lauric acid, palmitic acid, stearic acid, or a combination thereof. In various aspects, lubricant compositions are provided that include a petroleum or a synthetic base oil and about 40% or less by weight of a liquid lubricant composition containing oil from the seeds of the Brassicaceae Orychophragmus violaceus, preferably those that have been esterified with one or more fatty acids. In various aspects, semisolid lubricant composition are provided containing an emulsion of (i) a thickener and (ii) an oil from the seeds of the Brassicaceae Orychophragmus violaceus, preferably those that have been esterified with one or more fatty acids.

Abstract: Methods are provided for treating a subject with a therapeutic dose of anti-CD47 agent by administering a primer agent prior to administering a therapeutically effective dose of an anti-CD47 agent to the subject.

Abstract: A medication bottle includes an outer container wall, an inner container wall and a fluid, such as an aversive liquid, located between the walls. In another aspect, the fluid is located within separate compartments or channels located between the walls where the walls contact or are secured to each other. A further aspect provides a removeable cap including multiple sensors, at least one of which is a biometric sensor.

Abstract: Provided herein is a method for automatically controlling inspired oxygen delivery, including: receiving signals representing a plurality of input oxygen saturation (SpO2) values for a patient; generating control values based on the input SpO2 values and a target SpO2 value; and generating output inspired oxygen concentration (FiO2) values based on the control values and reference inspired oxygen concentration (rFiO2) values; wherein the control values include: immediate control values, generated based on the input SpO2 values, the target SpO2 value, and an immediate gain coefficient; accumulation control values, generated based on the input SpO2 values, the target SpO2 value, and an accumulation gain coefficient; and predictive control values, generated based on the input SpO2 values, the target SpO2 value, and a predictive gain coefficient; wherein the immediate gain coefficient is determined based on the rFiO2 value; and wherein a non-linear compensation weighting is applied to the accumulation control val

Abstract: Disclosed herein is a vaccine comprising a Middle East Respiratory Syndrome coronavirus (MERS-CoV) antigen. The antigen can be a consensus antigen. The consensus antigen can be a consensus spike antigen. Also disclosed herein is a method of treating a subject in need thereof, by administering the vaccine to the subject.

Abstract: Selected artifacts, which may be based on distortions or selected attenuation features, may be reduced or removed from a reconstructed image. Various artifacts may occur due to the presence of a metal object in a field of view. The metal object may be identified and removed from a data that is used to generate a reconstruction.

Abstract: The disclosure describes a tunneling field effect transistor having an overlapping structure between the source and drain regions providing a greater tunneling area. The source or drain region may be a doped region in a semi-conductive substrate. The other source or drain region may be formed by epitaxial deposition over the doped region. The gate is formed over the epitaxial region where the doped and epitaxial regions overlap. The doped region may be formed in a fin structure with the epitaxial region and gate being formed on the top and sides of the fin.

Abstract: The present disclosure provides compositions, methods, and devices for sensing, detecting, and/or selectively capturing phosphate from water. An exemplary method includes: contacting a ligand or a rare earth metal complex of a ligand as described herein with an aqueous phosphate-containing medium at a pH of 5 to 12 under conditions sufficient to bind phosphate (e.g., reversibly bind phosphate). In certain embodiments, the method further includes releasing the bound phosphate by contacting the bound phosphate complex with an aqueous medium at a pH of 0 to 4 under conditions sufficient to release the bound phosphate.

Abstract: An organic light emitting diode device comprising: a light emitting layer or layers combining both an emissive material comprising a boron subphthalocyanine, or first emitting layer component, that emits substantially orange light; and an emissive material emitting blue light, or second emitting layer component; wherein in combination, the first emitting layer component and the second emitting layer component, in combination, produces an overall white or near-white light emission.

Abstract: The presently disclosed subject matter provides a coating composition which allows for the co-delivery of two or more bioactive agents with independent control of loading level and release profile for each bioactive agent, an implantable medical device coated with the coating composition, and methods for preparing the coating composition.

Abstract: An engine room undercover assembly for a vehicle includes an aerofin mounted on a lower side surface of the undercover to guide airflow under an undercover. In the engine room undercover assembly, the aerofin is configured to maintain a state of being inserted and folded into the undercover when the vehicle is stopped or travels at a speed of less than or equal to a predetermined speed. When the vehicle travels at the speed greater than the predetermined speed, the aerofin protruded to the outside of the undercover to guide the airflow under the undercover.

Abstract: A method for producing soluble PDIA2, compositions containing it, and methods for its use.

Abstract: Contact of endothelial cells with inhibitors of inhibin and/or the alpha subunit of inhibin can be utilized to modify the activity of endothelial cell expression products including SMAD 1/5. Methods can also include inhibiting Alk1 and/or endoglin as components of inhibin-activated pathway of SMAD 1/5 signaling. Methods can be combined with other anti-angiogenesis therapies such as anti-VEGF therapies. Methods can be utilized in treatment of inhibin-expressing cancers (e.g., ovarian cancer, pancreatic cancer) as well as other pathologies such as preeclampsia and PCOS.

Abstract: An operation method of an optimal route searching device includes: acquiring topology transformed map information; extracting a plurality of candidate routes based on the topology transformed map information; calculating a travel cost for each of the plurality of candidate routes based on a cost function; and determining a candidate route corresponding to a lowest cost one of the calculated travel costs as a travelling route.