Abstract: A dry adhesive includes a first plurality of fiber segments mechanically interlocked with a second plurality of fiber segments. A dry adhesive can include a first plurality of fibers mechanically interlocked with a second plurality of fibers or a single plurality of fibers having a first end region mechanically interlocked with a second end region. The fiber segments and fibers can be aligned, electrospun nanofibers. One or more continuous and scalable methods of making aligned fibers are also provided. One or more apparatuses are also provided.

Abstract: The invention relates to the inhibition of expression of mutant KRAS sequences using RNA interference, antisense oligonucleotides, and chemically-modified oligonucleotides.

Abstract: Methods and devices for tissue remodeling and repair of collagenous tissues, including tendons, ligaments, and bone, as well as scalable connective tissue manufacturing, are provided. Collagen fibers are assembled by extensional strain-induced flow crystallization of collagen monomers. Extensional strain also drives the fusion of already formed short collagen fibrils to produce long-range, continuous fibers. Wearable devices for controlled tissue remodeling and wound healing deliver a tissue remodeling solution to a tissue repair site. The remodeling solution, together with appropriate application of strain to the tissue remodeling site, accelerate healing, prevent injury, and reduce scar formation.

Abstract: A hybrid method and system for data encryption significantly reduces the computational cost of encryption and reduces the cost of the processors needed to perform encryption and decryption.

Abstract: A method for making blackbody radiation source is provided. A blackbody radiation cavity and a carbon nanotube array located on a substrate are provided. A black lacquer layer is coated on an inner surface of the blackbody radiation cavity. A pressure is applied to the carbon nanotube array to form a carbon nanotube paper. The carbon nanotube paper is placed on the black lacquer layer. The substrate is peeled off to make the carbon nanotube paper bond to the black lacquer layer. An adhesive tape is placed on the carbon nanotube paper. And then the adhesive tape peeling off to separate carbon nanotubes in the carbon nanotube paper from the adhesive tape and bond to the black lacquer layer, the carbon nanotubes vertically aligned and forms the carbon nanotube array.

Abstract: The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA or RNA-targeting systems comprising a novel DNA or RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.

Abstract: Cytotoxic compounds containing a phenyl core, amide link(s), an imidazolinone or a propenamide moiety. Also described are pharmaceutical compositions incorporating the cytotoxic compounds and methods for treating cancer. These compounds are cytotoxic against breast, prostate, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.

Abstract: A method, system, and apparatus for remote patient monitoring or tracking sepsis-related indicators or markers in ambulatory patients or outpatients. The method, system, and apparatus is devised or configured to provide remote patient monitoring of patient vitals signs for determining the risk for sepsis.

Abstract: The disclosure relates to compounds and compositions for bone formation, fracture treatment, bone grafting, bone fusion, cartilage maintenance and repair and methods related thereto. In certain embodiments, the disclosure relates to compositions comprising one or more compound(s) disclosed herein, such as clotrimazole, honokiol, magnolol, tacrolimus, pimecrolimus, sirolimus, everolimus, temsirolimus, spironolactone, fluticasone, fluticasone propionate, fluticasone furoate, linezolid, telmisartan, chlorambucil, retinol, isotretinoin, acitretin, etretinate, retinoic acid (tretinoin), teniposide, mitomycin C, cytarabine, decitabine, vinblastine, vincristine, vindesine, vinorelbine, valrubicin, doxorubicin, daunorubicin, epirubicin, idarubicin, mitoxantrone, pixantrone, plicamycin, pazopanib, topotecan, camptothecin, irinotecan, sunitinib, derivatives, or salt thereof, for use in bone growth processes.

Abstract: Methods of forming graphene may include reacting a dispersed mixture, comprising fly ash, a charged heteroaromatic compound, particularly a pyridinium compound, such as a 1-(4-pyridyl)-pyridinium salt, and a solvent, particularly an alcohol, such as ethanol, with a polymeric oxidizing agent, preferably polymer-supported pyridinium chlorochromate, to form a second mixture; and contacting the second mixture at a temperature of 120 to 180° C. with a gas stream comprising at least 0.1 vol. % CH4 and at least 10 vol. % H2 to form graphene on the fly ash. Methods of managing waste may comprise using fly ash waste to produce graphene. Devices for implementing such methods may involve steel cylindrical reaction vessels including a cover through which a valve-stoppable pipe is fed, which reaction vessel is at least partially surrounded by a heating device, and suitable for handling solvent and fly ash, as well as for receiving gas inflow through the pipe.

Abstract: Methods and software utilizing artificial neural networks (ANNs) to estimate density and/or flow (speed) of objects in one or more scenes each captured in one or more images. In some embodiments, the ANNs and their training configured to provide reliable estimates despite one or more challenges that include but are not limited to, low-resolution images, low framerate image acquisition, high rates of object occlusions, large camera perspective, widely varying lighting conditions, and widely varying weather conditions. In some embodiments, fully convolutional networks (FCNs) are used in the ANNs. In some embodiments, a long short-term memory network (LSTM) is used with an FCN. In such embodiments, the LSTM can be connected to the FCN in a residual learning manner or in a direct connected manner. Also disclosed are methods of generating training images for training an ANN-based estimating algorithm that make training of the estimating algorithm less costly.

Abstract: There is provided novel small molecule E3 ubiquitin ligase protein binding ligand compounds, having utility in PROteolysis Targeted Chimeras (PROTACs), as well as processes for the preparation thereof, and use in medicine. There is particularly provided PROTACs which bind to a protein within the bromo- and Extra-terminal (BET) family of proteins, and especially to PROTACs including novel small molecule E3 ubiquitin ligase protein binding ligand compounds which selectively induce degradation of the BRD4 protein within the bromodomain of the BET family of proteins.

Abstract: It is an object to provide a novel wet wiper in which a sterilization effect and a wiping/cleaning effect are maintained even when the wet wiper is stored for a long period of time. A wet wiper is provided which includes: a fabric; and a chlorine-based treatment agent included in the fabric, wherein the chlorine-based treatment agent includes at least one of chlorous acid (HClO2), chlorite ion (ClO2?), and chlorine dioxide (ClO2) as an effective chlorine component.

Abstract: A wood heating system comprises an electric power source, a first electrode assembly, a second electrode assembly, and a control system. The first electrode assembly is connected to the electric power source and is adapted to make electrical contact with a first end of a wood length to apply electric power to the wood length. The first electrode assembly comprises at least two electrode segments. The second electrode assembly is adapted to make electrical contact with a second end of the wood length. The control system is adapted to selectively connect/disconnect electric power flow between the electric power source and at least one electrode segment of the first electrode assembly.

Abstract: A system for stimulating tissue generally comprises a resorbable implant. The resorbable implant includes a substrate, at least one contact, and a transceiver, wherein the substrate, the at least one contact, and the transceiver are resorbable. The system also includes a controller configured to communicate with the transceiver of the resorbable implant and a power supply connected to the controller. The controller delivers power to the resorbable implant from the power supply. The resorbable implant delivers electrical stimulation to tissue when the resorbable implant receives power.

Abstract: The present invention relates to a loaded-to-frame detection equipment for backfill grouting of a shield tunnel, including an automatic loaded-to-frame transmission apparatus, a ground penetrating radar, and an intelligent backfill grouting processing and analysis software. The equipment is integrated by using software and hardware, and can implement real-time visual detection of a backfill grouting layer in a shield construction process. The loaded-to-frame automatic transmission apparatus mainly includes a track, a synchronous belt, a transmission mechanism, a servo machine, and a drive and reducer; and a new air-coupled radar detection apparatus is carried on the loaded-to-frame automatic transmission apparatus and is installed on a shield frame. With the shield performs tunneling, circular detection on a grouting body of the shield and visual layered display of the grouting body are implemented.

Abstract: A novel alga mutant having improved pigment productivity is provided. The mutant can be used to produce carotenoid-based pigments, particularly, xanthophyll by using a small amount of energy, and thus can effectively produce pigment on an industrial level. In addition, the mutant can be used as a source for foods, health functional foods, and medications which contain a pigment. Further, when account is taken of the physiological characteristics of the euryhaline microalgae Dunaliella and the geological characteristics of Korean, the three sides of which are in contact with the sea, sea-water can be used as a culture medium, with the expectation of reducing the cost and leading to the development of related industries.

Abstract: A planetary gear device configured by combining a plurality of planetary gear mechanisms includes first and second planetary gear mechanisms sharing a carrier, wherein each planetary gear mechanism is composed of an internal gear Ik (k is an integer equal to or larger than 2) and a planetary gear Pk which is engaged with the internal gear Ik and revolves in a circumferential direction of the internal gear, the planetary gear Pk of each planetary gear mechanism is composed of a spur gear in the form of an external gear, the planetary gears Pk of the planetary gear mechanisms share a central axis or have central axes integrally connected to integrally rotate on a common rotation central axis line or are integrated with each other to integrally rotate on the common rotation central axis line in order to configure the entire planetary gear device as a two-stage gear mechanism, the planetary gear device is configured such that the number of teeth zp1 of a first planetary gear constituting the first planetary gear

Abstract: Disclosed are methods for minimizing x-ray scattering artifacts, the method comprising: contacting an object with an x-ray scattering mitigation material. The contacting can comprise coating the x-ray scattering material on the object, including spraying a solution of suspension of an x-ray scattering mitigation material onto the object or dry powder coating the object with a x-ray scattering mitigation material. Alternatively, the contacting can comprise immersing the object in a fluid comprising the x-ray scattering material. The fluid can be a gas, a liquid, or a gel. The disclosed x-ray scattering mitigation material can be optimized for mitigating Compton radiation scattering or for mitigating Rayleigh radiation scattering. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: Acinetobacter lysin polypeptides and variants peptides with killing activity against gram negative bacteria. Methods for treating bacterial infections or bacterial colonization using Acintobacter lysin polypeptides.