Abstract: Disclosed herein is a polysaccharide aerogel comprising cotton cellulose fibres and a method of preparing the polysaccharide aerogel. The method comprises: mixing cotton cellulose fibres and a cross-linker to form a mixture; sonicating the mixture; freezing the sonicated mixture; and freeze drying the frozen mixture to form an aerogel. A further embodiment provides a polysaccharide aerogel comprising cotton cellulose fibres and paper cellulose fibres in a weight ratio of 1:1 to 1:6 and a method of preparation thereof wherein in the mixing step, the paper cellulose fibres are added to the cotton cellulose fibres to form a mixture.

Abstract: Methods for the recovery of lipids, sugars, and proteins from microbial biomass by enzymatic digestion are disclosed. The methods involve treating microalgae with a fungal acid protease, or with a mixture of at least one protease and at least one amylase.

Abstract: An attraction system includes a fluid source configured to emit a fluid stream with a geometry that facilitates internal reflection, a transmitter configured to transmit a signal through the fluid stream such that the signal is enclosed in the fluid stream via internal reflection and the signal comprises a parameter, a sensor configured to receive the signal via the fluid stream and provide data indicative of the parameter, and a control system communicatively coupled to the sensor. The control system includes a processor and a memory, and the memory includes instructions that cause the processor to receive the data indicative of the parameter from the sensor, and operate the attraction system based on the parameter.

Abstract: Aspects of the present disclosure include compositions that make use of phosphorus and/or nucleobase protecting groups which find use in the synthesis of long polynucleotides. Phosphorus protecting groups are provided that help increase the stepwise coupling yield and/or phosphorous protecting groups that can be removed during the oxidation step. Amidine nucleobase protecting groups are provided that find use in the subject compositions and methods which provides for e.g., increased resistance to depurination during polynucleotide synthesis. In some instances, the methods and compositions disclosed herein utilize a combination of the phosphorus and amidine nucleobase protecting groups in the synthesis of polynucleotides having a sequence of 200 or more monomeric units in length. Also provided are methods for synthesizing a polynucleotide (e.g., a DNA) using one or more compounds disclosed herein.

Abstract: The present invention relates to novel oligonucleotides comprising at least one locked nucleoside and at least one triazole inter-nucleoside linkage linkage of Formula A or Formula B and methods of making the same.

Abstract: A nanoparticle with tunable radial gradients of compositions extending from the center of the nanoparticles. The nature of the gradient preserves the metallic state of the nanoparticles, the diffusion of the constituents, and the oxidation of the interface. The gradients can be purposely varied to allow for specific applications in fields ranging from corrosion, magnetics, information technology, imaging, electromagnetic absorption, coating technologies, and immuno-precipitation. The nanoparticles can be easily used to advance many areas of industry, technology, and life sciences.

Abstract: Fidelity-driven runtime thermal management for near-sensor architectures is provided. In this regard, a runtime controller is provided for controlling an operational mode of a vision or imaging system driven by fidelity demands. The runtime controller is responsible for guaranteeing the fidelity demands of a vision application and coordinating state transfer between operating modes to ensure a smooth transition. Under this approach, the vision application only needs to provide the runtime controller with high-level vision/imaging fidelity demands and when to trigger them. The runtime controller translates these demands into effective thermal management. To do this, the runtime controller applies application-specific requirements into appropriate policy parameters and activates temperature reduction mechanisms, such as clock gating and task offload.

Abstract: A dual-gate transistor and its production method are disclosed. An auxiliary gate is connected to the power supply of the integrated circuits, to form thick and high square-shaped potential barrier of minority carriers adjacent to the drain electrode, while the potential barrier is transparent for the majority carriers from the source electrodes. The potential barrier can effectively inhibit reverse minority carrier tunneling from the drain electrode at large drain-source voltage. The transistor can be easily turned on at small drain-source voltage, without significantly decreasing the on-state current. The dual-gate transistor can significantly suppress ambipolar behavior with increased current on/off ratio and reduced power consumption, and maintain the high performance. Based on transistors, strengthened CMOS circuits can have high noise margin, low voltage loss, reduced logic errors, high performance and low power consumption.

Abstract: A system includes a medium disposed on a base, a plurality of transducers coupled to the base, and a controller communicatively coupled to the plurality of transducers such that each individual transducer of the plurality of transducers is individually addressable by the controller. The controller is configured to receive feedback and to instruct at least some of the individual transducers of the plurality of transducers to activate to move the medium on the base to create a shaped surface based on the feedback.

Abstract: A chemical vapor deposition process comprising heating a porous metal template at a temperature range of 500 to 2000° C.; and passing a gas mixture comprising a carrier gas carrying along a vapor of an organometallic compound and at least one of a carbon precursor gas and a boron nitride precursor gas through the heated metal template is provided. The heating temperature causes the decomposition of the organometallic compound vapor into metal particles, the carbon precursor gas into graphene domains, and/or the boron nitride precursor gas into hexagonal-boron nitride domains. The graphene domains and/or the hexagonal-boron nitride domains nucleate and grow on the metal particles and the metal template to form a three-dimensional interconnected porous network of graphene and/or the hexagonal-boron nitride. A foam-like structure produced by a process as described above is also provided.

Abstract: A platinum(II) complex loaded on a mesosilicalite nanocarrier having a hierarchical silicalite characterized by a molar ratio of aluminum to silica in a range of 1:3000 to 1:1000. The hierarchical silicalite includes mesopores of a hexagonal structure, and micropores of silicalite structure with a microporous volume in the range of 0.05 cc/g to 0.1 cc/g. The mesosiliclite nanocarrier loaded with the platinum(II) complex is suitable for treatment of cancer, in particular, breast, cervical, and colon cancers.

Abstract: Due to potential sampling errors (due to small tissue samples not necessarily directly from the developing tumor) and limited optical resolution (˜1 micron), cancer may be missed or detected too late for optimal treatment, or conservative interpretation of indeterminate findings could lead to unnecessary surgery. The novel technology herein—Spatial-domain Low-coherence Quantitative Phase Microscopy (SL-QPM)—can detect structural alterations within cell nuclei with nanoscale sensitivity (0.9 nm) (or nuclear nano-morphology) for “nano-pathological diagnosis” of cancer. SL-QPM uses original, unmodified cytology and histology specimens prepared with standard clinical protocols and stains. SL-QPM can easily integrate in existing clinical pathology laboratories. Results quantified the spatial distribution of optical path length or refractive index in individual nuclei with nanoscale sensitivity, which could be applied to studying nuclear nano-morphology as cancer progresses.

Abstract: The present disclosure describes the thermodynamic design and concentrations necessary to design probe compositions with desired optimal specificity that enable enrichment, detection, quantitation, purification, imaging, and amplification of rare-allele-bearing species of nucleic acids (prevalence <1%) in a large stoichiometric excess of a dominant-allele-bearing species (wildtype). Being an enzyme-free and homogeneous nucleic acid enrichment composition, this technology is broadly compatible with nearly all nucleic acid-based biotechnology, including plate reader and fluorimeter readout of nucleic acids, microarrays, PCR and other enzymatic amplification reactions, fluorescence barcoding, nanoparticle-based purification and quantitation, and in situ hybridization imaging technologies.

Abstract: This invention relates to the field of energy storage devices, and especially electrochemical energy storage devices where an electroactive moiety is chemically attached to a conductive polymer In particular, the invention relates to the design and fabrication of electrodes for the use in electrochemical storage devices having an electrochemically active conjugate. The electrochemically active conjugate preferably has an electroactive moiety selected from electroactive metal center, an electroactive organic species, or an electroactive non-metal species. Depending on the selected electroactive moiety, it can be attached either directly or through an appropriate linker to the conductive polymer.

Abstract: A flexible and stretchable fabric based electrode-polymer electrolyte battery described herein comprises at least one electrochemical cell. The electrochemical cell comprises a first stretchable electrode having a first active material coupled with a first stretchable fabric current collector, a second stretchable electrode having a second active material coupled with a second stretchable fabric current collector, a stretchable separator configured between the first and second electrodes, and at least one stretchable encapsulant material, wherein the stretchable material encapsulates the electrochemical cell and is capable of reversible bending, twisting, folding and stretching.

Abstract: A method of killing bacteria and an antibiotic kit are provided herein. The method includes treating the bacteria with a DNA condensation-inducing compound; and subsequently treating the bacteria with an Eis inhibitor. The kit includes a DNA condensation-inducing compound packaged together with an Eis inhibitor.

Abstract: The invention provides amphiphilic liquid crystalline brush block copolymers that can readily self-assemble to nanoparticles in aqueous solutions and also allow for encapsulation of hydrophobic pharmaceutically active molecules.

Abstract: Systems and methods for determining optimal temporal patterns of neural stimulation are disclosed. According to an aspect, a method includes selecting a temporal pattern for neural stimulation. The method also includes determining a mutation type for altering a pattern of pulses of the temporal pattern. The method also includes identifying a location within the pattern of pulses of the temporal pattern to alter based on the determined mutation type. The method further includes altering the pattern of pulses of the temporal pattern based on the identified location and mutation type for application of the altered temporal pattern to a subject.

Abstract: The invention discloses a fixed bed counter-current regeneration device for ion exchange resin and the method of use, relates to the field of ion exchange resin regeneration. The device comprises a cyclone separator, a regeneration reactor, a fully mixed resin reactor, a desorption solution storage tank, and a regenerant storage tank, wherein the cyclone separator is placed on top of the regeneration reactor, the upper part of the cyclone separator is connected to the fully mixed resin reactor.

Abstract: Solid oxide fuel cells that include an alumina substrate as support are described. The alumina substrate supported SOFCs can exhibit desirable electrochemical characteristics including high performance at intermediate temperatures and excellent thermal stability. The alumina substrate support is formed according to a modified phase-inversion process that forms a series of aligned micro-channels extending from a first side to a second opposite side of the support enabling gas distribution between an electrode (e.g., an anode) located on one side of the alumina substrate and the other, opposite side of the alumina substrate.