Patents Assigned to University
  • Enantioselective cross dehydrogenative coupling reactions and compounds synthesized by the reactions
    Patent number: 11174238
    Abstract: Disclosed are enantioselective cross dehydrogenative coupling reactions for synthesizing tetrahydropyran compounds. Novel tetrahydropyran compounds may be synthesized by the disclosed methods as well as tetrahydropyran precursor compounds for synthesizing various naturally occurring compounds. The enantioselective cross dehydrogenative coupling reactions utilize in situ Lewis Acid activation in combination with oxidative formation of an oxocarbenium ion to provide a highly efficient and selective coupling reaction for synthesizing tetrahydropyran compounds.
    Type: Grant
    Filed: December 11, 2019
    Date of Patent: November 16, 2021
    Assignee: Northwestern University
    Inventors: Karl A. Scheidt, Ansoo Lee, Richard C. Betori
  • Organic-inorganic hybrid nanoflower and preparation method thereof
    Patent number: 11174476
    Abstract: The technical field of enzyme immobilization, and particularly, an organic-inorganic hybrid nanoflower and a preparation method thereof. The organic-inorganic hybrid nanoflower is a flower-like immobilized enzyme formed by self-assembly of a layered rare earth compound as an inorganic carrier and a biological enzyme as an organic component. The layered rare earth compound is Ln2(OH)5NO3·nH2O, where Ln is one or more of La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, or Y, and n=1.1-2.5. The biological enzyme is one or more of ?-amylase, horseradish peroxidase, or laccase. A layered rare earth compound is used as the inorganic carrier for the organic biological enzyme to form the flower-like immobilized enzyme. The immobilized enzyme has better stability and higher catalytic performance when compared with a free enzyme.
    Type: Grant
    Filed: August 12, 2020
    Date of Patent: November 16, 2021
    Assignee: Guilin University of Technology
    Inventors: Xiaoli Wu, Ke Ren, Mengwu Wang, Zewen He, Shaoling Peng, Jichan Ning, Yuanli Liu
  • Electroacoustic transducer
    Patent number: 11178493
    Abstract: An electroacoustic transducer includes: a diaphragm; a magnetic circuit having a magnetic gap; a frame that holds the diaphragm and the magnetic circuit; a voice coil having one end portion positioned within the magnetic gap and the other end portion coupled to the diaphragm; and a low friction material that is disposed in a sliding portion formed by the voice coil and the magnetic circuit, and includes polymer compounds swollen with liquid.
    Type: Grant
    Filed: March 26, 2020
    Date of Patent: November 16, 2021
    Assignees: Panasonic Corporation, KYOTO UNIVERSITY, National University Corporation YOKOHAMA National University
    Inventors: Hidetoshi Hiraoka, Yoshinobu Tsujii, Keita Sakakibara, Ken Nakano
  • Selective activators of the intermediate conductance CA2+activated K+ channel KCa3.1 and their methods of use
    Patent number: 11173146
    Abstract: Benzoxazole and indole type KCa3.1 activators as well as the therapeutic uses of such compounds in human or animal subjects and their use in ex vivo preservation of organs or tissues.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: November 16, 2021
    Assignee: The Regents of the University of California
    Inventors: Heike Wulff, Nichole Coleman, Brandon M. Brown, Aida Olivan-Viguera, Ralf Kohler
  • Nanolipogel vehicles for controlled delivery of different pharmaceutical agents
    Patent number: 11173119
    Abstract: A “nanolipogel” is a delivery vehicle including one or more lipid layer surrounding a hydrogel core, which may include an absorbent such as a cyclodextrin or ion-exchange resin. Nanolipogels can be constructed so as to incorporate a variety of different chemical entities that can subsequently be released in a controlled fashion. These different incorporated chemical entities can differ dramatically with respect to size and composition. Nanolipogels have been constructed to contain co-encapsulated proteins as well as small hydrophobic drugs within the interior of the lipid bilayer. Agents incorporated within nanolipogels can be released into the milieu in a controlled fashion, for example, nanolipogels provide a means of achieving simultaneous sustained release of agents that differ widely in chemical composition and molecular weight. Additionally, nanolipogels can favorably modulate biodistribution.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: November 16, 2021
    Assignee: Yale University
    Inventors: Tarek M. Fahmy, Eric Stern, Richard A. Flavell, Jason Park, Alyssa Siefert, Stephen H. Wrzesinski
  • Solar cell
    Patent number: 11177398
    Abstract: A silicon solar cell with high photoelectric conversion efficiency is disclosed. A solar cell for converting light incident from an outside into electricity according to the present invention includes a substrate, a lower electrode, a ferroelectric layer, an auxiliary electrode, a first conductivity-type semiconductor layer, a second conductivity-type semiconductor layer, and an upper electrode. The lower electrode is formed on the substrate. The ferroelectric layer is formed on the substrate and outside the lower electrode. The auxiliary electrode is formed on the ferroelectric layer. The first conductivity-type semiconductor layer is formed on the lower electrode and the auxiliary electrode. The second conductivity-type semiconductor layer is formed on the first conductivity-type semiconductor layer, and is composed of a semiconductor of a second conductivity type opposite to a first conductivity type.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: November 16, 2021
    Assignee: University of Seoul Industry Cooperation Foundation
    Inventor: Byung-Eun Park
  • Systems and methods for a connected augmented environment
    Patent number: 11173408
    Abstract: Systems and methods presented herein include an amusement park system that includes an augmented experience system. The augmented experience system is configured to track guest interactions of a plurality of guests of an amusement park with one or more employees of the amusement park, one or more mobile devices, one or more wearable devices, one or more themed devices, or one or more physical objects disposed within a real-world environment of the amusement park. The augmented experience system is also configured to augment the real-world environment of the amusement park based at least in part on data relating to the guest interactions.
    Type: Grant
    Filed: August 17, 2020
    Date of Patent: November 16, 2021
    Assignee: Universal City Studios LLC
    Inventors: Neil Andrew Leiba, Wei Cheng Yeh, Travis Jon Cossairt, Erica Lynn McCay
  • Keratin bioceramic compositions
    Patent number: 11173233
    Abstract: A malleable bone graft composition is described. The composition comprises: (a) keratose; (b) particulate filler; (c) antibiotic; and (d) water. The invention may be provided in sterile form in an container, and optionally lyophilized. Methods of treating a fracture with such compositions are also described.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: November 16, 2021
    Assignee: Wake Forest University Health Sciences
    Inventor: Mark E. Van Dyke
  • Venturi vacuum drawback assemblies and dual orifice venturi valve assemblies
    Patent number: 11175086
    Abstract: A venturi vacuum drawback assembly includes a fluid supply passage that supplies the fluid to the device, a fluid return passage that returns the fluid to the device, a shutoff valve positioned on the fluid supply passage, a bypass passage, a bypass valve positioned on the bypass passage, and a venturi valve positioned on the bypass passage downstream of the bypass valve. The bypass passage includes an inlet and an outlet. The inlet is connected to the fluid supply passage upstream of the shutoff valve, and the outlet connected to the fluid return passage. The venturi valve includes a venturi inlet, a venturi outlet, and a primary orifice positioned between the venturi inlet and the venturi outlet. The primary orifice is connected to a drawback opening on the fluid supply passage by a conduit. The drawback opening of the fluid supply passage is positioned downstream of the shutoff valve.
    Type: Grant
    Filed: March 25, 2020
    Date of Patent: November 16, 2021
    Assignee: Universal Flow Monitors, Inc.
    Inventors: Lars O. Rosaen, Peter E. Hackett
  • Three stack hybrid white OLED for enhanced efficiency and lifetime
    Patent number: 11177452
    Abstract: OLEDs containing a stacked hybrid architecture including a phosphorescent organic emissive unit and two fluorescent organic emissive units are disclosed. The stacked hybrid architecture includes a plurality of electrodes and a hybrid emissive stacked disposed between at least two of the electrodes. The stack contains at least three emissive units and at least two charge generation layers. At least one of the three emissive units is a phosphorescent organic emissive unit and at least two of the three emissive units are fluorescent organic emissive units. More specifically, the two fluorescent organic emissive units may be blue organic emissive units that emit light from the same or different color regions.
    Type: Grant
    Filed: January 9, 2017
    Date of Patent: November 16, 2021
    Assignee: Universal Display Corporation
    Inventors: Michael Stuart Weaver, Julia J. Brown
  • Fluorine and hydrogen-based adhesive compositions and methods of making the same
    Patent number: 11174418
    Abstract: Embodiments of the present disclosure pertain to adhesive compositions that include a fluorinated molecule and a hydrogen-containing molecule that are non-covalently associated with one another. The molecules may be non-covalently associated with one another through dipole-dipole interactions that create a fluorine-hydrogen electronegativity difference between at least some of the fluorine atoms of the fluorinated molecule and at least some of the hydrogen atoms of the hydrogen-containing molecule. The fluorinated molecule and the hydrogen-containing molecule may be in different phases, such as a liquid phase for one molecule and a solid phase for the other molecule. Additional embodiments pertain to methods of enhancing an adhesiveness of a surface by applying an adhesive composition of the present disclosure to the surface.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: November 16, 2021
    Assignees: William Marsh Rice University, Board of Regents of the University of Texas System
    Inventors: Alin C. Chipara, Mircea Chipara, Chandra S. Tiwary, Pulickel M. Ajayan
  • Method and apparatus for differentiating between human and electronic speaker for voice interface security
    Patent number: 11176960
    Abstract: A system for distinguishing between a human voice generated command and an electronic speaker generated command is provided. An exemplary system comprises a microphone array for receiving an audio signal collection, preprocessing circuitry configured for converting the audio signal collection into processed recorded audio signals, energy balance metric determination circuitry configured for calculating a final energy balance metric based on the processed recorded audio signals, and energy balance metric evaluation circuitry for outputting a command originator signal based at least in part on the final energy balance metric.
    Type: Grant
    Filed: June 18, 2019
    Date of Patent: November 16, 2021
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Patrick G. Traynor, Logan E. Blue, Luis Vargas
  • Dual-layer insole apparatuses for diabetic foot lesion prevention and related methods
    Patent number: 11172731
    Abstract: Dual-layer insole apparatuses for diabetic foot lesion prevention and related methods are provided. Some insole apparatuses have a body defining a plurality of cavities configured to be coupled to a fluid source. The fluid source can deliver fluid to vary internal pressures of the cavities. The body further defines an insole-shaped structure.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: November 16, 2021
    Assignees: The Board of Regents of the Universsity of Texas Systems, The University of North Texas Health Science Center At Fort Worth
    Inventors: Muthu B. J. Wijesundara, Wei Carrigan, Ryan Landrith, Metin Yavuz
  • Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria
    Patent number: 11174288
    Abstract: Disclosed are peptides comprising an amphiphilic backbone and a cationic heparin-binding motif peptide. The peptides can be used in methods of antimicrobial treatment.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: November 16, 2021
    Assignee: Northeastern University
    Inventors: Run Chang, Keerthana Subramanian, Mian Wang, Thomas J. Webster
  • Biogas upgrading technology for power generation
    Patent number: 11174163
    Abstract: A method for powering an internal combustion engine or other device powered by combustion includes a step of feeding a first stream of biogas to a catalytic reforming reactor in which the first stream contacts oxygen to form a first product stream comprising synthesis gas. The first product stream is combined with a second stream of biogas to form a second product stream. The second product stream is provided to a device powered by combustion. A system implementing the method is also provided.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: November 16, 2021
    Assignees: University of Southern California, ES Engineering Services, LLC
    Inventors: Theodore Tsotsis, Richard Prosser, Mingyuan Cao, Sasan Dabir
  • Methods of diagnosing and treating cancer comprising ME1
    Patent number: 11175296
    Abstract: The present disclosure provides a method of determining treatment for cancer comprising identifying the absence of malic enzyme 1 (ME1) and treating with an inducer of ferroptosis.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: November 16, 2021
    Assignee: Washington University
    Inventors: Brian Van Tine, Sara S. Lange, Jeff Kremer
  • Polymer-clay composite and organoclay
    Patent number: 11173230
    Abstract: The invention relates to a polymer-clay composite material comprising clay nanoparticles and a polymer, and wherein (a) the polymer comprises phosphate and/or phosphonate ligands; or (b) the polymer-clay composite further comprises linker molecules comprising a phosphate or phosphonate ligand, wherein the linker molecules are arranged to be anchored to the polymer. The invention further relates to organoclays, BMP-clay composite material. Uses, treatments, and manufacturer of the material are also provided.
    Type: Grant
    Filed: February 12, 2019
    Date of Patent: November 16, 2021
    Assignee: University of Southampton
    Inventors: Richard Oreffo, Jonathan Dawson, David Gibbs, Jons Hilborn, Dmitri Ossipov
  • LC-based optical display system
    Patent number: 11175536
    Abstract: An optically active structure and a display device are presented. The device utilized an optically active structure comprising liquid crystal material and a plurality of nanorods configured to emit light in one or more predetermined ranges in response to pumping light. Variation in orientation of the liquid crystal varies orientation of the nanorods and modulated light emission therefrom.
    Type: Grant
    Filed: September 20, 2015
    Date of Patent: November 16, 2021
    Assignees: Yissum Research Development Company Of The Hebrew University of Jerusalem Ltd., Merck Patent GmbH
    Inventors: Uri Banin, Hagai Arbell, Bernhard Rieger, Ming-Chou Wu
  • Apparatus and method for calibrating or resetting a charge detector
    Patent number: 11177122
    Abstract: A CDMS may include an ELIT having a charge detection cylinder (CD), a charge generator for generating a high frequency charge (HFC), a charge sensitive preamplifier (CP) having an input coupled to the CD and an output configured to produce a charge detection signal (CHD) in response to a charge induced on the CD, and a processor configured to (a) control the charge generator to induce an HFC on the CD, (b) control operation of the ELIT to cause a trapped ion to oscillate back and forth through the CD each time inducing a charge thereon, and (c) process CHD to (i) determine a gain factor as a function of the HFC induced on the CD, and (ii) modify a magnitude of the portion of CHD resulting from the charge induced on the CD by the trapped ion passing therethrough as a function of the gain factor.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: November 16, 2021
    Assignee: The Trustees Of Indiana University
    Inventors: Martin F. Jarrold, Andrew W. Alexander, Aaron R. Todd
  • Engineered bacteria for production and release of therapeutics
    Patent number: 11174486
    Abstract: Some embodiments described herein relate to cells which have been genetically engineered to release a polypeptide when a population of the cells reaches a desired density. In some embodiments, the released polypeptide may be a therapeutic polypeptide. In some embodiments, the therapeutic polypeptide kills tumor cells or which inhibits the growth of tumor cells.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: November 16, 2021
    Assignees: The Regents of the University of California, Massachusetts Institute of Technology
    Inventors: Jeff Hasty, Lev Tsimring, Muhammad Omar Din, Arthur Prindle, Sangeeta Bhatia, Tal Danino