Abstract: Provided is a hydrogen generating apparatus adaptable to fluctuating hydrogen demand, particularly by enabling large-scale hydrogen production, generating pure hydrogen at a high yield. The hydrogen generating apparatus 1 includes a tabular dielectric body 2 having a first surface 11 with a source gas flow channel 13 formed as a recess and a second surface 12 approximately parallel to the first surface 11, a grounding electrode 3, a hydrogen flow channel plate 4 with a hydrogen flow channel 18 and a hydrogen outlet 19, being arranged on a first surface 11 side of dielectric body 2, a hydrogen separation membrane 5 between source gas flow channel 13 and hydrogen flow channel 18, and a high-voltage power supply 6 that causes electric discharge in source gas flow channel 13 between hydrogen separation membrane 5 and grounding electrode 3. Hydrogen separation membrane 5 transmits hydrogen generated by electric discharge in source gas flow channel 13 into hydrogen flow channel 18.

Abstract: The subject invention provides novel devices and methods for the detection and quantification of neutrophil elastase activity in biological samples.

Abstract: The invention provides a capillary isoelectric focusing (cIEF) system based on a sandwich injection method for automated chemical mobilization. This system was coupled with an electrokinetically pumped nanoelectrospray interface to a mass spectrometer. The nanoelectrospray emitter employed an acidic sheath electrolyte. To realize automated focusing and mobilization, a plug of ammonium hydroxide was first injected into the capillary, followed by a section of mixed sample and ampholyte. As focusing progressed, the NH3H2O section was titrated to lower pH buffer by the acidic sheath buffer. Chemical mobilization started automatically once the ammonium hydroxide was consumed by the acidic sheath flow electrolyte.

Abstract: A transparent panel is provided. The transparent panel includes a polarization plate, a transparent diffusion plate which is disposed on one side of the polarization plate and is configured to transmit light incident from a side of the polarization plate and to reflect and diffuse a light incident from an opposite side of the polarization plate, a ¼ wavelength plate which is disposed on one side of the transparent diffusion plate and is configured to convert a polarization direction of an incident light, and a lens part which is disposed on one side of the ¼ wavelength plate. The lens part includes a lens array comprising a birefringent material having different refractive indexes according to a polarization direction of an incident light, and a refractive index alignment member configured to transmit or refract the light according to a polarization direction of a light that penetrates the lens array.

Abstract: The present invention relates to a polyarylene sulfide resin, a method for producing the same, a poly(arylene sulfonium salt), and a method for producing the same. The production method comprises a step of obtaining a poly(arylene sulfonium salt) comprising a terminal group including at least one functional group selected from the group consisting of a carboxy group, a hydroxy group and an amino group, and a step of dealkylating or dearylating the poly(arylene sulfonium salt) to obtain a polyarylene sulfide resin, and a polyarylene sulfide resin comprising a terminal group including a functional group obtainable by the production method.

Abstract: An improved inflow performance model that provides the performance of oil wells having any slant angle within the entire azimuth of 0-90 degrees, in saturated and under saturated reservoirs. A generalized model is formulated by normalizing the coefficients of inflow performance relationship (IPR) model by performing a linear regression analysis. The generalized model is further modified to account for skin factor and is also integrated with a straight line IPR to be suitable for determining the performance of under saturated oil wells. For the case of flowing bottom-hole pressures above bubble point pressure, the straight line IPR model is used to determine the flow rate of the oil well, whereas for the case of having bottom-hole pressure below the bubble point pressure, the generalized IPR model is used to determine the flow rate performance of the well.

Abstract: The present invention is directed to transduced T cells expressing at least 100,000 molecules of human somatostatin receptor 2 (SSTR2), which improves PET/CT imaging sensitivity. The present invention is also directed to transduced T cells expressing SSTR2 and chimeric antigen receptor (CAR). In one embodiment, the CAR is specific to human ICAM-1 and the CAR comprises a binding domain that is scFv of anti-human ICAM-1, or an I domain of the ?L subunit of human lymphocyte function-associated antigen-1. In another embodiment, the CAR is specific to human CD19, and the CAR comprises a binding domain that is scFv of anti-human CD19. The present invention is further directed to using the above transduced T cells for monitoring T cell distribution in a patient by PET/CT imaging and/or treating cancer.

Abstract: An antenna device is provided. The antenna device includes a first radiating conductor including a feeding portion and a radiating portion extending from the feeding portion, the feeding portion including a feeding terminal and a shorting pin, a ground electrically connected with the first radiating conductor via the shorting pin and configured to provide a reference potential for the first radiating conductor, and a first switch circuit provided on a side of the radiating portion and configured to selectively connect the radiating portion with the ground. The first radiating conductor is configured to form at least part of an inverted-F antenna structure when the first switch circuit is open and to form at least part of a loop antenna structure when the first switch circuit is closed.

Abstract: The present invention provides modified metformin compounds, particularly mito-metformin compounds, and pharmaceutical compositions thereof. Methods of using the compounds to provide neuroprotection and in the treatment and/or prevention of neurodegenerative diseases are also described.

Abstract: The present disclosure relates generally to compounds having activity as voltage-gated sodium channel blockers and their use in the field of therapeutic treatment, including the therapy or management of conditions associated with excessive, unwanted, inadequate or otherwise undesirable sodium ion passage through cellular membranes via voltage-gated sodium channels. In some embodiments, the disclosure relates to aryloxy-substituted amines for use as sodium channel blockers or modulators. Methods for their manufacture and compositions containing the compounds are also disclosed.

Abstract: Some embodiments include a genetically engineered cell comprising a nucleic acid encoding a detectable polypeptide operably linked to the Msi1 or Msi2 promoter and genetically engineered organisms comprising these genetically engineered cells.

Abstract: A system in accordance with present embodiments includes a plurality of wearable devices and a virtual queue control system configured to maintain respective virtual queues for respective attractions and in communication with the plurality of virtual queuing attraction stations. The virtual queue control system is configured to receive communications from the plurality of virtual queuing stations and add guests to the respective virtual queues based on the communications.

Abstract: Two isoforms of thyroid receptor alpha (THR?1 and THR?2) have been found to be associated with the growth of cancer. Use of inhibitors of THR?1 (Formula I) and/or agonists of THR?2 (Formula II) in the treatment of such cancers is disclosed. Treatment of other disorders associated with such receptors is also contemplated, as is the use of diagnostic methods for predicting therapeutic outcomes based on the levels of expression of THR?1 and THRa?2 in a tissue sample.

Abstract: The impact of plastid size change in both monocot and dicot plants has been examined. In both, when plastid size is increased there is an increase in biomass relative to the parental lines. Thus, provided herein are methods for increasing the biomass of a plant, comprising decreasing the expression of at least one plastid division protein in a plant. Optionally, the level of chlorophyll in the plant is also reduced.

Abstract: A method of fabricating an electrical circuit assembly on a flexible substrate comprises: identifying one or more bending-sensitive elements of an electrical circuit assembly, each bending-sensitive element having a performance that varies when said bending-sensitive element is flexed; splitting said one or more bending-sensitive elements into a first portion and a second portion, wherein the first portion and the second portion are functionally equivalent and together equate to said bending-sensitive element; printing the first portion of said bending-sensitive element on a first surface of the flexible substrate; printing the second portion of said bending-sensitive element on a second surface of the flexible substrate, diametrically opposite the first portion such that bending of the flexible substrate has an opposite effect on each of the first and second portions thereby serving to substantially cancel the effect on each portion out; and electrically connecting the first portion and the second portion.

Abstract: The present disclosure describes systems and method for generating surgical maps that provide a surgeon with information regarding the placement of features of interest. More particularly, the system is configured to display optical coherence tomography (OCT) images to a medical professional. The medical professional can select anatomical features, biomarkers, and other features of interest within each of the OCT images. The system can then translate the location of the features of interest within the OCT images to an en face image to generate a map of the features that the medical professional can use for surgical guidance.

Abstract: The present disclosure relates to methods and systems for signal processing using coordinate descent technique for solving technical implementation problems that are expressed as unit-modulus least squares (UMLS) and unit-modulus quadratic program (UMQP) problems. Embodiments provide for iteratively minimizing an objective function of a signal vector associated with a UMLS/UMQP problem expression over a set of coordinates of the signal vector to a convergence point. The objective function is minimized with respect to a vector element corresponding to a selected coordinate index, while other vector elements that do not correspond to the selected coordinate index are fixed. Accordingly, at each iteration, minimizing the objective function involves a solution to a one-dimensional univariate quadratic minimization. Embodiments also provide various coordinate index selection rules that include a cyclic CD rule (CCD), a randomized CD rule (RCD), randomly permuted CD rule (RPCD), and a greedy CD rule (CCD).

Abstract: Gene-modified, lymphoid-tissue-homing dendritic cells that comprise a 1-alpha-hydroxylase gene and a retinaldehyde dehydrogenase 2 gene, where the 1-alpha-hydroxylase gene is expressed to produce functional 1-alpha-hydroxylase enzyme and the retinaldehyde dehydrogenase 2 gene is expressed to produce functional retinaldehyde dehydrogenase 2 gene enzyme. A method for treating one or more than one inflammation-related condition or disease, the method comprising administering gene-modified, lymphoid-tissue-homing dendritic cells that comprise a 1-alpha-hydroxylase gene and a retinaldehyde dehydrogenase 2 gene, where the 1-alpha-hydroxylase gene is expressed to produce functional 1-alpha-hydroxylase enzyme and the retinaldehyde dehydrogenase 2 gene is expressed to produce functional retinaldehyde dehydrogenase 2 gene enzyme.

Abstract: Systems and methods for utilizing cooperation facilitators to achieve joint message and network state cooperation in accordance with various embodiments of the invention are disclosed. One embodiment of the invention includes: a plurality of transmitters; a receiver that has access to at least partial network state information and that includes a decoder configured to decode signals received via a multiple terminal channel from the plurality of transmitters using the at least partial network state information; and a cooperation facilitator. In addition, at least some of the plurality of transmitters are configured to transmit message information to the cooperation facilitator and the cooperation facilitator is configured to generate cooperation parameters based upon the message information and the manner in which state information is utilized by the receiver to decode signals received via the multiple terminal channel.

Abstract: This disclosure includes a method for pushing an active agent into a patient's ear via the device. The agent can be pushed to a treatment site.