Abstract: A system for producing dry nanoparticles from a liquid includes a closed tubing system which incorporates a mister, heater and an electrostatic collector therein. The system is able to produce dry nanoparticles from liquid-suspensions and from solvent solutions.

Abstract: Disclosed are inhibitors of human galactokinase of formula (I) that are useful in treating or preventing a galactokinase mediated disease or disorder, e.g., galactosemia. Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one inhibitor of the invention, and a method of treating or preventing such disease or disorder in a mammal. Formula (I).

Abstract: Implementations herein relates to effect-directed identification of targeted and non-targeted androgen disruptors. The implementations include primary separation, androgenic activity testing, high throughput separation and preparation of toxicants, active component scanning based on high performance liquid chromatography-time of flight mass spectrometry, targeted screening of suspicious androgenic substances, non-target identification of androgenic compounds combining mass spectrum, chromatography and toxicity characteristics and toxicity confirmation. The implementations perform separation using SPE and preparative separation in series to obtain high throughput separation fractions, utilize DMSO as a protective agent to optimize concentration of second fractions, utilize target databases to achieve target identification of key toxicants.

Abstract: A zinc anode material for secondary cells includes zinc-containing particles that are coated with a coating composition containing at least one oxide of a metal selected from titanium, zirconium, magnesium, tin and yttrium. The surface localization ratio of the coating composition of Equation (1) ranges from 1.6 to 16. In Equation (1), the surface metal atomic ratio of the coating composition is represented by Equation (2), and the bulk metal atomic ratio of the coating composition is represented by Equation (3).

Abstract: Compounds suitable for use in providing male contraception, an assay method for identifying such compounds, and methods of providing contraception using the compounds, are provided. In one embodiment, the compounds described herein mimic the binding of anti-EPPIN antibodies to EPPIN, and thus inhibit the forward motility of sperm in humans and other primates. In another embodiment, the compounds described herein inhibit or enhance EPPIN-semenogelin binding, and inhibit forward motility of sperm. The assays described herein identify compounds which inhibit sperm motility, and can be carried out in a high throughput manner, using labeled recombinant EPPIN and semenogelin. The compounds can be used in oral or transdermal compositions to temporarily and reversibly inhibit male fertility. They can also be used in addition to, or in place of, spermicides in spermicidal compositions, such as those used in conjunction with condoms, diaphragms, and spermicidal jellies.

Abstract: A photon counting system is provided. The photon counting system comprises an analog domain and a digital domain in communication with the analog domain. A detector is configured to detect photons. An analog digital converter is provided in the digital domain, while an amplifier circuit is provided in the analog domain that is configured to receive the detector's output, wherein the amplifier circuit's output is in communication with the analog digital converter. The output of the analog digital converter is in communication with a signal processing system that may perform accumulation of signals and store them in memory.

Abstract: The present disclosure relates to a communication scheme for combining an IoT technology and a 5G communication system for supporting a higher data transmission rate beyond a 4G system, and a system therefor. The present disclosure may be applied to a smart service (for example, a smart home, a smart building, a smart city, a smart car or connected car, healthcare, digital education, retail business, a security and security related service, or the like) on the basis of a 5G communication technology and an IoT related technology.

Abstract: Embodiments of the disclosure relate to selective metal silicide deposition methods. In one embodiment, a substrate having a silicon containing surface is heated and the silicon containing surface is hydrogen terminated. The substrate is exposed to sequential cycles of a MoF6 precursor and a Si2H6 precursor which is followed by an additional Si2H6 overdose exposure to selectively deposit a MoSix material comprising MoSi2 on the silicon containing surface of the substrate.

Abstract: A method for manufacturing a freestanding film having at least one population of through holes cumulatively totaling at least 1% of the film area, wherein the standard deviation of hole diameters is less than 25% and a thickness less than 25 micrometers, The film provides a carrier substrate, a photo-curable material, a release agent and deposits a photo-curable material on the substrate, selectively curing the material and leaving uncured material in the pattern of holes, dissolving away the uncured material and removing the cured material from the carrier substrate. Methods and apparatus are described.

Abstract: A method for independent real and reactive power flow control without sensing receiving end voltage in a power flow controller (PFC) includes calculating a first reference phase angle, calculating a first reference voltage, modifying the first reference phase angle calculated using a first phasor modifier, calculating a first reference current for a first terminal, calculating a second reference phase angle for current through the first terminal, calculating a second reference voltage across a second CMI by subtracting voltages at the first terminal and a second terminal, and controlling the first CMI and the second CMI for controlling the power flow through the PFC.

Abstract: Instruments, assemblies and methods are provided for undertaking imaging techniques (e.g., microscopic imaging techniques). The present disclosure provides improved imaging techniques, equipment and systems. More particularly, the present disclosure provides advantageous microscopy/imaging assemblies with single-frame sample autofocusing using multi-LED illumination. The present disclosure provides for assemblies and methods for single-frame rapid sample autofocusing without a z-scan. Potential applications for the disclosed assemblies/methods include, without limitation, whole slide imaging, optical metrology, wafer inspection, DNA sequencing and other high-throughput imaging applications where the sample may need to be scanned over a large field of view. The assemblies/methods advantageously utilize multiple LEDs for sample illumination. A captured image includes multiple copies of the sample, and one can recover the distance between these copies. The distance is directly related to the defocus distance.

Abstract: Compounds comprising a ligand LA selected from the group consisting of Formula I and Formula II may be useful as blue phosphorescent materials in OLED devices. The materials were determined computationally to have appropriate triplet energies for use as blue emitters and to possess sufficient chemical stability for use in devices.

Abstract: Various embodiments relate to a compound of the formula (I): wherein X, X1, R1—R4 and R7 are defined herein, as well as pharmaceutical compositions comprising compounds of the formula (I) and methods of treating an HIV infection comprising administering a therapeutically effective amount of one or more compounds of formula (I), or a pharmaceutical compositions comprising compounds of the formula (I), to a patient in need thereof.

Abstract: The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels.

Abstract: A battery includes: 1) an anode; 2) a cathode; 3) a separator disposed between the anode and the cathode, wherein the separator includes at least one functional layer; and 4) a sensor connected to the at least one functional layer to monitor an internal state of the battery.

Abstract: Systems, devices, and techniques are provided for operating a display and/or an illumination source based upon the direction of a user's gaze and/or a desired illumination level in a monitored area. One or more elements may be controlled with sensor input and application lighting preferences. For example, when a user receives a video call, light may be activated to illuminate their face. When the user is looking at the display, the display will be at the brightness necessary for the lighting conditions. When the user looks away from the screen, the screen may dim further and the lighting elements for the desk can brighten. Similarly, embodiments may adjust the lighting in a monitored location based upon lighting levels identified in other areas.

Abstract: A rehabilitation system includes a portable patient workstation configured to facilitate in-home rehabilitation therapy. In some embodiments, the workstation includes a computer configured to host computer-based activities that provide rehabilitative exercise to a patient when the patient participates in the activities, a monitor electrically connected to the computer and configured to display screens of the computer-based activities, a table upon which the monitor can be supported, a tabletop console supported on the table, the console including multiple integral user interface devices that are connected to the computer and adapted to receive patient inputs while the patient is participating in the activities, and a network interface device with which data can be transmitted and received by the patient workstation via a network.

Abstract: Adaptive windowing of insufficient cyclic prefix (CP) for joint minimization of intersymbol interference (ISI) and adjacent channel interference (ACI) is provided. The proposed subcarrier specific windowing scheme improves the signal-to-interference ratio (SIR) even when the cyclic prefix (CP) is insufficient. Average optimal window lengths depend only on the power density profiles (PDPs), and although instantaneous optimal window lengths depend on users' channel impulse responses (CIRs), fluctuation is little. Therefore, subcarrier specific windowing outperforms fixed windowing, even with outdated window lengths in the case of powerful interferers.

Abstract: The presently disclosed subject matter relates to a method for predicting increased risk of obesity on a non-obese subject. More particularly, the presently disclosed subject matter relates to a method of predicting increased risk of obesity in a non-obese subject by determining a level of neurotensin expression in a biological sample from the subject and comparing the level of neurotensin expression in the sample with a control level. The presently disclosed subject matter further relates to a method of preventing and/or treating obesity in a subject in need thereof by administering to the subject an effective amount of an agent that inhibits neurotensin.

Abstract: Three dimensional printed objects having surface coatings, such as a hydrophobic coating or metalized surface, 3D printed substrates having an outer surface that can be tuned by application of such a coating, and methods for the fabrication of such objects and substrates are described. A surface initiator is incorporated into the 3D substrate during layer-by-layer printing, and the surface coated by surface-initiated atom transfer radical polymerization (SI-ATRP).