Abstract: The present prevent relates to a method of sparsifying a channel using beamforming in a wireless communication system, the method including inserting pilot symbols into resources allocated among resource elements constituting a time-frequency grid; calculating beamforming weights for sparsifying a beamformed time-domain channel; and beamforming frequency-domain channels of a plurality of antennas mapping the pilot symbols by using the beamforming weights.

Abstract: Herein is described kinetic assay, in which individual binding events are detected and monitored during sample incubation. This method uses interferometric reflectance imaging to detect thousands of individual binding events across a multiplex solid phase sensor with a large area. A dynamic tracking procedure is used to measure the duration of each event. From this, the total rates of binding and de-binding as well as the distribution of binding event durations are determined. Systems and components for performing the kinetic assay are also described.

Abstract: A compound having a formula M(LA)x(LB)y(LC)z, where ligand LA is ligand LB is and LC is is disclosed.

Abstract: A cycloidal rotor air vehicle includes an airframe, a first cycloidal rotor assembly supported by the airframe and configured to rotate about a first axis of rotation relative to the airframe, the first cycloidal rotor assembly including a blade having a longitudinal axis oriented parallel to the first axis of rotation, a first motor configured to rotate the first cycloidal rotor assembly about the first axis of rotation, a first servo coupled to the blade of the first cycloidal rotor assembly and configured to adjust the pitch of the blade, and a control system supported on the airframe and configured to control the operation of the first motor and the first servo.

Abstract: There is provided herein a roof for a reactor vessel that utilizes a weighted floating cover. The cover is free to move up and down within the vessel as the fluid level changes during the operational cycle. In some embodiment, the cover itself is not directly connected to the reactor vessel or its sidewall, but instead is held in place and supported from above by truss-like support members that permit movement of the cover in concert with the changing fluid level in the vessel. In an embodiment, the support members are anchored proximate to the top of the reactor vessel.

Abstract: A system for providing neurostimulation includes an external device (“external exciter”) and an implanted device. The external exciter includes an energy source which inductively powers the implanted device. Examples of such external exciters include devices having at least one of: ultrasonic transducers, Radio Frequency (RF) transmitters, and solar cells. The implanted device includes circuitry that limits its maximum energy output to a predetermined saturation threshold such that excess stimulation from the external exciter does not raise the output of the implanted device beyond the saturation threshold. The output signal of the external exciter is then pulse-width modulated in order to produce a desired amount of output stimulation from the implanted device to stimulate the bioelectrically excitable tissue at a desired level.

Abstract: Methods and apparatus for separating, concentrating and/or detecting molecules based on differences in binding affinity to a probe are provided. The molecules may be differentially modified. The molecules may be differentially methylated nucleic acids. The methods can be used in fields such as epigenetics or oncology to selectively concentrate or detect the presence of specific biomolecules or differentially modified biomolecules, to provide diagnostics for disorders such as fetal genetic disorders, to detect biomarkers in cancer, organ failure, disease states, infection or the like.

Abstract: The present invention provides a genetically recombinant vaccinia virus effective in preventing or treating cancer. Specifically, the present invention provides a recombinant vaccinia virus lacking functions of VGF and O1L and having a gene encoding B5R in which an SCR domain has been deleted. Specifically, the present invention provides a vaccinia virus comprising two polynucleotides, a polynucleotide encoding IL-7 and a polynucleotide encoding IL-12; a combination kit of two vaccinia viruses, a vaccinia virus comprising a polynucleotide encoding IL-7 and a vaccinia virus comprising a polynucleotide encoding IL-12; and use of the two vaccinia viruses in combination.

Abstract: A composition of matter for tissue engineering is disclosed. The composition comprises a plurality of electrospun albumin fibers, wherein an outer surface of the composition comprises a pattern of ridges or indentations, wherein the ridges or indentations are wider than the diameter of a single electrospun albumin fiber of the plurality of electrospun albumin fibers.

Abstract: Nanocomposite films comprising carbon nanotubes dispersed throughout a polymer matrix and further comprising at least two surfaces with differing amounts of carbon nanotubes and differing electrical resistivity values are provided. Nanocomposite films comprising a polymer layer, a conductive nanofiller layer, and a polysaccharide layer having antistatic properties are provided. In particular, nanocomposites comprising polyvinyl alcohol as the polymer, graphene as the conductive nanofiller and starch as the polysaccharide are provided. In addition, processes for forming the nanocomposites, methods for characterizing the nanocomposites as well as applications in or on electrical and/or electronic devices are provided.

Abstract: Products, compositions, systems, and methods for modifying a target structure which mediates or is associated with a biological activity, including treatment of conditions, disorders, or diseases mediated by or associated with a target structure, such as a virus, cell, subcellular structure or extracellular structure. The methods may be performed in situ in a non-invasive manner by application of an initiation energy to a subject thus producing an effect on or change to the target structure directly or via a modulation agent. The methods may further be performed by application of an initiation energy to a subject in situ to activate a pharmaceutical agent directly or via an energy modulation agent, optionally in the presence of one or more plasmonics active agents, thus producing an effect on or change to the target structure. Kits containing products or compositions formulated or configured and systems for use in practicing these methods.

Abstract: A method for preventing counterfeiting of an object (e.g. paper) is described. The method comprises capturing an image of at least a portion of the object, wherein the portion of the object whose image is captured is at least partially transparent, and wherein the captured image includes features of the internal structure of the object (e.g. the texture of the paper resulting from the arrangement of fibres from which the paper is made). The method further comprises generating, based on the image, a code that encodes features of the internal structure of the object, and recording the code. Generating the code may comprise applying a filter to the image to obtain a filtered image, and processing the filtered image to obtain a binary code. The filter may be a Gabor filter, and processing the filtered image may comprise applying a Gray code to the filtered image. The method may further comprise encrypting the binary code, and recording the code may comprise recording the encrypted binary code.

Abstract: Disclosed are systems, components of systems, and methods for sensing extracellular ligands and/or modulating expression of an endogenous or exogenous gene in a cell. In some embodiments, the disclosed systems and methods comprise or utilize first and second exogenous extracellular sensors and/or nucleic acid sequences encoding the first and second exogenous extracellular sensors, wherein the first exogenous extracellular sensor comprises: a) a ligand binding domain; b) a transmembrane domain; c) a protease cleavage site; and d) a functional domain comprising an RNA-binding subdomain fused to a transcription regulatory subdomain; and the second exogenous extracellular sensor comprises: e) a ligand binding domain, f) a transmembrane domain, and g) a protease domain that cleaves the protease cleavage site of the first exogenous extracellular receptor.

Abstract: The use of microresonators with sharp corners (rectangular and square-shaped) can be limited by severe energy loss at the corners. The effect of incorporating fillet design at sharp corners (rounding of corners) of such single mode optical microresonators is described. The effect on quality factor, free spectral range (“FSR”), and energy loss for varying values of fillet radii are quantified and compared with standard circular microring resonator. It is shown that the selection of optimum fillet radius for sharp-cornered microresonators provide higher quality factor than that of the conventional circular resonators.

Abstract: In the present invention, a mass and heat exchange system and method are disclosed, wherein water is preferentially absorbed by a non-toxic, non-corrosive liquid desiccant after passing through a hydrophilic, non-porous membrane, and embodiments wherein mixing stages are provided to reduce the surface concentration of water at the desiccant-membrane interface are also provided.

Abstract: A true random number generator with a dynamic compensation capacity comprises a loop control logic, a shift register, a sensitive amplifier and a load matching unit. The sensitive amplifier comprises a first PMOS transistor, a second PMOS transistor, a third PMOS transistor, a fourth PMOS transistor, a first NMOS transistor, a second NMOS transistor and two NMOS arrays. Each NMOS array comprises a third NMOS transistor, a fourth NMOS transistor, a fifth NMOS transistor, a sixth NMOS transistor, a seventh NMOS transistor, an eighth NMOS transistor, a ninth NMOS transistor, a tenth NMOS transistor, an eleventh NMOS transistor, a twelfth NMOS transistor and a thirteenth NMOS transistor. The load matching unit comprises a first D flip-flop and a second D flip-flop and is configured at an output terminal and an inverted output terminal of the sensitive amplifier. The true random number generator has the advantages of simple feedback regulation and high robustness.

Abstract: Methods for inducing growth inhibition or apoptosis of Bcl-2-expressing cells and treatments of Bcl-2 expressing cancers are provided. Additionally, assays for agents that can induce apoptosis of Bcl-2 expressing cells are disclosed.

Abstract: The present disclosure relates to thin-film solar cells with improved efficiency and methods for producing thin-film solar cells having increased efficiency. In certain embodiments, thin-film solar cells having an efficiency of over 21%, over 20%, over 19%, over 15%, over 10%, etc. has been obtained using the methods of the disclosure. In certain aspects, the methods of the disclosure use passivation, passivating oxides, and/or doping treatments in increase the efficiency of the thin-film solar cells; e.g., CdTe-based thin-film solar cells.

Abstract: Provided are a compound of chemical formula 1 or 2 and a use thereof. The compound can be advantageously used in the prevention or treatment of metabolic diseases including type 2 diabetes, insulin resistance, or obesity, on the basis of a mechanism of autophagy activation through the promotion of lysosome production.

Abstract: A novel means that can suppress development of arteriosclerotic lesions and treat arteriosclerosis is disclosed. An antiarteriosclerotic agent according to the present invention comprises, as an active ingredient, a substance which selectively suppresses B2 cells. The substance which selectively suppresses B2 cells is, for example, an anti-CD23 antibody. A first aspect of the method of assisting in determining a condition of arteriosclerosis according to the present invention comprises measuring expression of at least one gene selected from particular gene groups using a sample isolated from a subject. A second aspect of the method comprises measuring the level of IgG3 and/or the level of total IgG in a serum sample isolated from a subject.