Abstract: A method for determining a length of a span of electrically conductive material, comprising a first voltage measurement across the entire span, and a second voltage measurement across a constant-length segment of the span. The dual measurements allow the calculation of the span length in a manner that is robust to many disturbances including ambient temperature, material temperature, and material stress and fatigue.
Type:
Grant
Filed:
May 12, 2017
Date of Patent:
November 5, 2019
Assignee:
Auburn University
Inventors:
Austin R. Gurley, David G. Beale, Royall M. Broughton
Abstract: Protein polymer-gold nanoparticles, compositions comprising protein polymer-gold nanoparticles, and uses of protein polymer-gold nanoparticles. A protein polymer-gold nanoparticle comprises a gold core and a plurality of protein polymer molecules coordinated to the gold core via a poly-histidine tag present on each protein polymer molecule. A protein polymer molecule comprises one or more elastin-like polypeptide domain and a coiled-coil region of Cartilage Oligomeric Matrix Protein domain or a variant thereof. For example, the protein polymer-gold nanoparticles can be used in methods of small molecule delivery to an individual.
Type:
Grant
Filed:
January 6, 2017
Date of Patent:
November 5, 2019
Assignee:
New York University
Inventors:
Jin Kim Montclare, Joseph Frezzo, Min Dai, Raymond Chen
Abstract: A dental treatment method is provided. In this method, a tooth of a patient is extracted and prepared to provide a root part. A root canal in the extracted tooth is prepared and treated. A post of an abutment is fitted into the root canal to attach the root part to the abutment. The abutment having the root part is attached to a dental implant. With the root part attached to the abutment, periodontal connective tissue maintains the jaw bone associated with the extracted tooth, without significant hard tissue loss.
Type:
Grant
Filed:
March 14, 2014
Date of Patent:
November 5, 2019
Assignee:
The Research Foundation for The State University of New York
Abstract: Disclosed are various examples related to ion or particle spectrometry utilizing a monolithic collimator and energy analyzer. In one example, a particle selection device includes a single substrate including a curved channel energy analyzer section and a straight channel collimator section, wherein particles pass through the collimator section and enter the energy analyzer section of the substrate. The channel outlets in the collimator section are aligned with the channel inlets of the energy analyzer section. Electric and/or magnetic fields can be applied across the channels of the energy analyzer for ion or particle discrimination. A particle detector at the outlet of the energy analyzer section can provide indications of detected ions and/or particles.
Type:
Grant
Filed:
April 4, 2017
Date of Patent:
November 5, 2019
Assignee:
West Virginia University
Inventors:
Earl Scime, Amy M. Keesee, Matthew Phillip Dugas, Steven Brian Ellison, Joseph Christopher David Tersteeg, Drew B. Elliott
Abstract: Genetically modified non-human animals expressing human EPO from the animal genome are provided. Also provided are methods for making non-human animals expressing human EPO from the non-human animal genome, and methods for using non-human animals expressing human EPO from the non-human animal genome. These animals and methods find many uses in the art, including, for example, in modeling human erythropoiesis and erythrocyte function; in modeling human pathogen infection of erythrocytes; in in vivo screens for agents that modulate erythropoiesis and/or erythrocyte function, e.g. in a healthy or a diseased state; in in vivo screens for agents that are toxic to erythrocytes or erythrocyte progenitors; in in vivo screens for agents that prevent against, mitigate, or reverse the toxic effects of toxic agents on erythrocytes or erythrocyte progenitors; in in vivo screens of erythrocytes or erythrocyte progenitors from an individual to predict the responsiveness of an individual to a disease therapy.
Type:
Grant
Filed:
May 18, 2015
Date of Patent:
November 5, 2019
Assignees:
Regeneron Pharmaceuticals, Inc., Yale University, Institute for Research in Biomedicine (IRB)
Inventors:
Andrew J. Murphy, Sean Stevens, Richard Flavell, Markus Gabriel Manz, Liang Shan
Abstract: Methods, systems, and devices are disclosed for implementing electro-optical modulators in which a resonating cavity structure is coupled to a transmission waveguide. In one example, the resonating structure includes a ring resonator whose coupling strength is controlled via an electrical control signal. The ring resonator is made of a capacitor comprising monolayer graphene sheets separated by a thick layer of dielectric material.
Abstract: The present invention relates to a wavelength-tunable type etalon comprising a liquid crystal layer, which comprises: a first substrate; a second substrate; a reflective coating film; a transparent electrode; an alignment layer, which is independently formed while covering the opposing surface of the transparent electrode; a liquid crystal layer, which is disposed in a space between each of the alignment layer s; and a sealing member, which is provided for sealing of the liquid crystal layer; and a method for manufacturing the same.
Type:
Grant
Filed:
July 12, 2017
Date of Patent:
November 5, 2019
Assignee:
Research & Business Foundation Sungkyunkwan University
Abstract: A method of predicting a disease or condition of a cornea or an anterior segment of an eye includes inputting input data into an AI model, processing the input data, and generating a set of scores and outputting a prediction. The input data may be representative of a cornea or anterior segment of an eye. Processing the input data may include processing the data through the plurality of convolutional layers, the fully connected layer, and the output layer. Each score of the set of scores may be generated by a corresponding node in the output layer. The output prediction may be related to the cornea or anterior segment of the eye represented by the input data processed through the AI model. The prediction may be determined by at least one score of the set of scores.
Type:
Grant
Filed:
July 27, 2018
Date of Patent:
November 5, 2019
Assignee:
University of Miami
Inventors:
Mohamed Abou Shousha, Amr Saad Mohamed Elsawy
Abstract: Novel microlens array architectures for enhanced light outcoupling from light emission are provided. Organic light emitting devices (OLEDs) that include an outcoupling layer including these novel microlens array architectures and method for fabricating such OLEDs are provided. These devices may be used to provide OLEDs with optimized light extraction.
Type:
Grant
Filed:
May 22, 2014
Date of Patent:
November 5, 2019
Assignees:
Universal Display Corporation, Kent State University
Inventors:
Yue Cui, Deng-ke Yang, Ruiqing Ma, Gregory McGraw, Julia J. Brown
Abstract: The present disclosure provides a depth filter medium comprising at least one elastomeric nonwoven web strengthened by combination with one or more structural support layers. The resulting material is particularly useful in the field of filtration, wherein particulates captured within the elastomeric nonwoven web can be readily released, such as by applying pressure to the web through backwashing. The elastomeric nonwoven web advantageously can stretch under such pressure and return substantially to its original structure and shape upon the removal of the pressure, rendering the filter available for reuse.
Abstract: Methods for treating a telomerase-expressing cell characterized by an over-activation of telomerase in a subject in need thereof comprising administering a pharmaceutical composition comprising a first amount of a 6-mercaptopurine analog, and a second amount of a telomerase inhibitor, wherein the first amount and the second amount together comprises an amount effective to reduce stability of telomere length and to induce cell death in the telomerase-expressing cell are provided. The methods can be used to treat patients with lung cancer, colon cancer, or cervical cancer.
Type:
Grant
Filed:
April 8, 2014
Date of Patent:
November 5, 2019
Assignee:
The Board of Regents of the University of Texas System
Abstract: A power controller for an AC power converter connected in series with a load and receiving power from or delivering power to a power source, the power controller comprising: a radial control block controlling a radial component of an electrical parameter of the AC power converter; and a chordal control block controlling a chordal component of the electrical parameter of the AC power converter. Also provided is a power system comprising one or more loads each connected in series to a power converter each controlled by a power controller as described above. There is also provided a method of controlling an AC power converter connected in series with a load and receiving power from a power source, the method comprising: controlling a radial component of an electrical parameter of the AC power converter; and controlling a chordal component of the electrical parameter of the AC power converter.
Type:
Grant
Filed:
November 13, 2014
Date of Patent:
November 5, 2019
Assignee:
The University of Hong Kong
Inventors:
Kwan Tat Mok, Siew Chong Tan, Shu Yuen Ron Hui
Abstract: Processes and reaction mixtures including non-aqueous solvent mixtures are presented. Non-aqueous solvent mixtures including fluoride salt and non-aqueous solvent combinations are provided that possess high fluoride ion concentrations useful for a range of applications, including organic synthesis. Further non-aqueous solvent mixtures are provided including a salt possessing a non-fluoride anion and a non-aqueous solvent that, when contacted with aqueous fluoride-containing reagents, extract fluoride ions to form non-aqueous fluoride-ion solutions possessing high fluoride-ion concentrations. The salts include an organic cation that does not possess a carbon in the ?-position or does not possess a carbon in the ?-position having a bound hydrogen. This salt structure facilitates its ability to be made anhydrous without decomposition. Example anhydrous fluoride salts include (2,2-dimethylpropyl)trimethylammonium fluoride and bis(2,2-dimethylpropyl)dimethylammonium fluoride.
Type:
Grant
Filed:
August 4, 2016
Date of Patent:
November 5, 2019
Assignees:
California Institute of Technology, The Regents of the University of California
Inventors:
Simon C. Jones, Victoria K. Davis, Christopher M. Bates, Nebojsa Momcilovic, Brett M. Savoie, Michael A. Webb, Thomas F. Miller, III, Robert H. Grubbs, Jennifer M. Murphy
Abstract: A calorimeter head and an associated system are provided. The calorimeter head provides symmetric circumferential laminar flow parallel to the bottom plane of a substrate plate of the calorimeter head. The calorimeter head defines a cavity which employs multiple tangentially arranged inlets for receipt of a flow of coolant from a control unit of the system.
Type:
Grant
Filed:
April 21, 2017
Date of Patent:
November 5, 2019
Assignee:
Board of Trustees of Northern Illinois University
Inventors:
Federico M. Sciammarella, Joseph S. Santner, Matthew J. Gonser, Justin Whiting, Daniel Nikolov
Abstract: A functionalized magnetic nanoparticle including an organometallic sandwich compound and a magnetic metal oxide. The functionalized magnetic nanoparticle may be reacted with a metal precursor to form in a catalyst for various C—C bond forming reactions. The catalyst may be recovered with ease by attracting the catalyst with a magnet.
Type:
Grant
Filed:
October 4, 2018
Date of Patent:
November 5, 2019
Assignee:
King Fahd University of Petroleum and Minerals
Inventors:
M. Nasiruzzaman Shaikh, Md. Abdul Aziz, Aasif Helal
Abstract: This invention relates to a system and methods for determining the placement of an object in a distributed key-value store by mapping the object to nodes in multidimensional hyperspace. A search function supports efficient object retrieval, even when the search query requests multiple objects and specifies them through non-primary keys. In response to a search query, the search is translated into hyperregions in the hyperspace to determine the set of nodes that hold the queried data object. The number of contacted nodes and the number of scanned objects are significantly reduced in comparison to prior art techniques.
Type:
Grant
Filed:
September 21, 2015
Date of Patent:
November 5, 2019
Assignee:
Cornell University
Inventors:
Emin Sirer, Nicole L. Caruso, Bernard Wong, Robert Escriva
Abstract: A device is described that can include a probe, a mobile device, and at least one processor. The probe can examine a corresponding anatomical part of a body. The mobile device can have a camera to take an image of the anatomical part of the body. The mobile device can execute a patient-application to process the image. The at least one processor can be configured to transmit the processed image to a server via a communication network. Related apparatuses, systems, methods, techniques and articles are also described.
Type:
Grant
Filed:
February 26, 2018
Date of Patent:
November 5, 2019
Assignee:
The Aga Khan University
Inventors:
Saleem Sayani, Muhammad Abdul Muqeet, Hafiz Imtiaz Ahmed
Abstract: Provided herein are materials for the promotion of tissue regeneration, and methods of promoting tissue regeneration and wound healing therewith. In particular, materials displaying laminin-derived peptide sequences that facilitate cell migration into the material, and methods of use thereof, are provided.
Type:
Grant
Filed:
May 12, 2016
Date of Patent:
November 5, 2019
Assignee:
Northwestern University
Inventors:
Yunxiao Zhu, Zdravka Cankova, Milan Mrksich, Guillermo A. Ameer
Abstract: The present invention includes methods of making, and compositions comprising, a uniformly lethal filovirus for outbred small mammals by mutation of the viral genome through serial passages in a small mammal, the method comprising the steps of: obtaining a filovirus strain from a human subject; passing the filovirus strain one or more times by intramuscular injection of one or more filovirus infected tissues into an inbred small mammal until uniform lethality is obtained; passing the filovirus strain in one or more human cell lines; passing the filovirus strain one or more times by intraperitoneal injection of one or more filovirus infected tissues into an outbred small mammal until uniform lethality is obtained; and isolating the uniformly lethal filovirus obtained thereby.
Type:
Grant
Filed:
September 9, 2016
Date of Patent:
November 5, 2019
Assignee:
Board of Regents, The University of Texas System
Inventors:
Joan B. Geisbert, Chad E. Mire, Thomas W. Geisbert, Robert W. Cross
Abstract: The present disclosure provides an aluminum alloy with enhanced penetration resistance for a heat exchanger, the alloy containing copper (Cu), silicon (Si), and iron (Fe) equal to or smaller than predetermined contents respectively, and further containing zirconium (Zr) and the remainder being aluminum (Al). Further, the present disclosure provides an aluminum extruded tube and/or an aluminum fin with enhanced penetration resistance made of the alloy respectively. Further, the present disclosure provides a heat exchanger comprising the tube and/or fin. Addition and content-control of the alloy element may spread corrosion initiations and suppress intergranular corrosion to create uniform corrosion. In this manner, the present alloy have superior corrosion resistance compared to pitting corrosion of a previous alloy for a heat exchanger, and, at the same time, have an extrusion rate equal to that of the previous A1070.
Type:
Grant
Filed:
September 26, 2014
Date of Patent:
November 5, 2019
Assignee:
Research & Busines Foundation Sungkyunkwan University